Market Value12,071,272,000
Total Holdings133
File Date2016-02-16
Original Filing (Click here)

All hedge funds or institutions that manage over $100M are required by the SEC to file quarterly reports on their holdings. These reports are called 13F reports. However, the filings are required the following quarter from the reporting period, which means that by the time the filing is made (and we see them), the information could be five months old.

For funds with long term positions that make few trades, the holdings might closely resemble their current holdings, even after several months. However, for funds that have high turnover, the holdings data we see might differ significantly from their current holdings. Institutions are required to report CALL and PUT options, and those positions are identified in the table. However, they are not required to report short positions.

Click the link icon to see the full transaction history.

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Security Imputed
Share Price
Prev
Shares
Current
Shares
Change
(Percent)
Prev Value
(USD x1000)
Current Value
(USD x1000)
Change
(Percent)
MGNX / MacroGenics, Inc.
BCRX / BioCryst Pharmaceuticals, Inc.
GBT / Global Blood Therapeutics Inc.
XNPT / XenoPort, Inc.
VTAE / Vitae Pharmaceuticals, Inc.
ONCE / Spark Therapeutics, Inc.
AERI / Aerie Pharmaceuticals Inc
ABUS / Arbutus Biopharma Corporation
CNCE / Concert Pharmaceuticals Inc
IRWD / Ironwood Pharmaceuticals, Inc.
CYCCP / Cyclacel Pharmaceuticals, Inc. - Preferred Stock
FMI / Foundation Medicine, Inc.
BTX.WS / BioTime, Inc. Warrants exp. 2018-10-01
ABBV / AbbVie Inc.
PTN / Palatin Technologies, Inc.
CMRX / Chimerix, Inc.
PGNX / Progenics Pharmaceuticals, Inc.
OSIR / Osiris Therapeutics, Inc.
NBRV / Nabriva Therapeutics Plc
45337CAK8 / Incyte Corporation Bonds 0.375% 11/15/2018
09061GAD3 / BioMarin Pharmaceutical Inc. Bond 1.875% 4/23/2017
ALDR / Alder BioPharmaceuticals, Inc.
GNMX / Aevi Genomic Medicine, Inc.
032420101 / Anacor Pharmaceuticals, Inc.
032420AC5 / Anacor Pharmaceuticals Inc. Bond 2.0% 15 OCT 2021
FLXN / Horizon Funds - Horizon Flexible Income ETF
PRQR / ProQR Therapeutics N.V.
DMTX / Dimension Therapeutics, Inc.
Arrowhead Research Corp. / (042797209)
375558AP8 / Gilead Sciences, Inc. Bond 1.625% 5/1/16
ARCT / Arcturus Therapeutics Holdings Inc.
JUNO / Juno Therapeutics, Inc.
LGND / Ligand Pharmaceuticals Incorporated
WINT / Windtree Therapeutics, Inc.
US00767EAB83 / Aegerion Pharmaceuticals, Inc. 2.0% Bond due 2019-08-15
451731103 / Ignyta, Inc.
IMDZ / Immune Design Corp.
OMER / Omeros Corporation
NDRM / NeuroDerm Ltd.
04269XAA3 / Array BioPharma Inc. Bonds 3.0% 6/1/2020
MDWD / MediWound Ltd.
ECYT / Endocyte, Inc.
BLPH / Bellerophon Therapeutics, Inc.
30161QAC8 / Exelixis, Inc. Bond
SVRA / Savara Inc.
220480AB3 / Amrn 3.5 1/32 Bond
US00448Q2012 / Achillion Pharmaceuticals, Inc.
FOMX / Foamix Pharmaceuticals Ltd.
INSM / Insmed Incorporated
ACAD / ACADIA Pharmaceuticals Inc.
AAAP / Advanced Accelerator Applications S.A
IDRA / Idera Pharmaceuticals, Inc.
ALNY / Alnylam Pharmaceuticals, Inc.
QLGN / Qualigen Therapeutics, Inc.
IMGN / ImmunoGen, Inc.
TRIL / Trillium Therapeutics Inc
SGMO / Sangamo Therapeutics, Inc.
VIRX / Viracta Therapeutics, Inc.
TGTX / TG Therapeutics, Inc.
STML / Stemline Therapeutics, Inc.
HALO / Halozyme Therapeutics, Inc.
CRIS / Curis, Inc.
MDVN / Medivation, Inc.
CYTR / LadRx Corp
74365AAB7 / Protalix BioTherapeutics, Inc. Bonds 4.5% 9/15/18
GHDX / Genomic Health, Inc.
CLLS / Cellectis S.A. - Depositary Receipt (Common Stock)
ZGNX / Zogenix Inc
US0153511094 / Alexion Pharmaceuticals, Inc.
LRMR / Larimar Therapeutics, Inc.
EPZM / Epizyme Inc
NBSE / NeuBase Therapeutics, Inc.
0HBB / Aimmune Therapeutics Inc
DYAX / Dyax Corp.
AGIO / Agios Pharmaceuticals, Inc.
DERM / Journey Medical Corporation
XLRN / Acceleron Pharma Inc
45337CAL6 / Incyte Corporation Bonds 1.25% 11/15/2020
BDSI / Biodelivery Sciences International
TRVN / Trevena, Inc.
MCRB / Seres Therapeutics, Inc.
/ Achaogen Inc
09061GAE1 / BioMarin Pharmaceutical Inc. Bond 0.75% 10/15/2018
US189464AB64 / Clovis Oncology, Inc. 2.5% 9/15/2021
ITCI / Intra-Cellular Therapies, Inc.
CLVS / Clovis Oncology Inc
GILD / Gilead Sciences, Inc.
SGYPQ / SYNERGY PHARMACEUTICALS INC DEL
CERS / Cerus Corporation
IONS / Ionis Pharmaceuticals, Inc.
KPTI / Karyopharm Therapeutics Inc.
GLPG / Galapagos NV - Depositary Receipt (Common Stock)
QURE / uniQure N.V.
AUPH / Aurinia Pharmaceuticals Inc.
ADAP / Adaptimmune Therapeutics plc - Depositary Receipt (Common Stock)
LOXO / Loxo Oncology, Inc.
MRNS / Marinus Pharmaceuticals, Inc.
ASMB / Assembly Biosciences, Inc.
US00484MAA45 / Acorda Therapeutics, Inc. Bond 1.750% 6/1
INCY / Incyte Corporation
AKTX / Akari Therapeutics, Plc - Depositary Receipt (Common Stock)
TENX / Tenax Therapeutics, Inc.
/ Array BioPharma, Inc.
ISEE / IVERIC bio Inc
ASND / Ascendis Pharma A/S - Depositary Receipt (Common Stock)
US33830X1046 / Five Prime Therapeutics Inc
APTO / Aptose Biosciences Inc.
MTEM / Molecular Templates, Inc.
ALDX / Aldeyra Therapeutics, Inc.
LJPC / La Jolla Pharmaceutical Co.
CPRX / Catalyst Pharmaceuticals, Inc.
SRRA / Sierra Oncology Inc
DSCI / Derma Sciences, Inc.
ACOR / Acorda Therapeutics, Inc.
BLCM / Bellicum Pharmaceuticals, Inc.
IOVA / Iovance Biotherapeutics, Inc.
CCXI / ChemoCentryx Inc
ENTA / Enanta Pharmaceuticals, Inc.
NVAX / Novavax, Inc.
RARE / Ultragenyx Pharmaceutical Inc.
NBIX / Neurocrine Biosciences, Inc.
76028H209 / Repros Therapeutics, Inc.
LIFE / aTyr Pharma, Inc.
NVTA / Invitae Corporation
DVAX / Dynavax Technologies Corporation
BLUE / bluebird bio, Inc.
BMRN / BioMarin Pharmaceutical Inc.
TARA / Protara Therapeutics, Inc.
XNCR / Xencor, Inc.
ALKS / Alkermes plc
AMRN / Amarin Corporation plc - Depositary Receipt (Common Stock)
SAGE / Sage Therapeutics, Inc.
AFMD / Affimed N.V.
HRTX / Heron Therapeutics, Inc.
NTRA / Natera, Inc.
ARAV / Aravive, Inc.
DBVT / DBV Technologies S.A. - Depositary Receipt (Common Stock)
SGEN / Seagen Inc
MRTX / Mirati Therapeutics, Inc.
NLTX / Neoleukin Therapeutics, Inc.