Market Value1,568,369,000
Total Holdings216
File Date2014-02-14
Original Filing (Click here)

All hedge funds or institutions that manage over $100M are required by the SEC to file quarterly reports on their holdings. These reports are called 13F reports. However, the filings are required the following quarter from the reporting period, which means that by the time the filing is made (and we see them), the information could be five months old.

For funds with long term positions that make few trades, the holdings might closely resemble their current holdings, even after several months. However, for funds that have high turnover, the holdings data we see might differ significantly from their current holdings. Institutions are required to report CALL and PUT options, and those positions are identified in the table. However, they are not required to report short positions.

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Security Imputed
Share Price
Prev
Shares
Current
Shares
Change
(Percent)
Prev Value
(USD x1000)
Current Value
(USD x1000)
Change
(Percent)
CYTR / LadRx Corp Call
NWBO / Northwest Biotherapeutics, Inc.
INSM / Insmed Incorporated Put
INSM / Insmed Incorporated Call
INSM / Insmed Incorporated
WINT / Windtree Therapeutics, Inc. Call
EXEL / Exelixis, Inc.
EXEL / Exelixis, Inc. Call
UNXLQ / Uni-Pixel, Inc. Put
GEVA / Synageva Biopharma Corp Call
GEVA / Synageva Biopharma Corp
ATHX / Athersys, Inc. Put
CNAT / Conatus Pharmaceuticals Inc.
MRK / Merck & Co., Inc. Call
MRK / Merck & Co., Inc. Put
UTHR / United Therapeutics Corporation
UTHR / United Therapeutics Corporation Call
DCTH / Delcath Systems, Inc.
TEVA / Teva Pharmaceutical Industries Limited - Depositary Receipt (Common Stock)
TEVA / Teva Pharmaceutical Industries Limited - Depositary Receipt (Common Stock) Put
ADXSW / Advaxis, Inc. Warrants
ANIP / ANI Pharmaceuticals, Inc.
ANTH / Anthera Pharmaceuticals, Inc. Call
AVNR / Avanir Pharmaceuticals Inc Call
ENTA / Enanta Pharmaceuticals, Inc.
EXEL / Exelixis, Inc. Put
US60877T1007 / Momenta Pharmaceuticals, Inc. Put
PCYC / Pharmacyclics
PGNX / Progenics Pharmaceuticals, Inc. Put
RNA / Avidity Biosciences, Inc. Put
SPDR S&P BIOTECHNOLOGY / ETF Put (78464A950)
STAA / STAAR Surgical Company Call
TRANSCEPT PHARMACEUTICALS INC / (89354M106)
WCG / Wellcare Health Plans, Inc. Put
SLXP / Salix Therapeuticals, Inc.
US0153511094 / Alexion Pharmaceuticals, Inc. Call
LUMO / Lumos Pharma, Inc. Call
LUMO / Lumos Pharma, Inc.
NKTR / Nektar Therapeutics
NKTR / Nektar Therapeutics Call
NKTR / Nektar Therapeutics Put
CYTR / LadRx Corp
BBI / Brickell Biotech Inc
GERN / Geron Corporation Call
TGTX / TG Therapeutics, Inc.
BMRN / BioMarin Pharmaceutical Inc.
ARNA / Arena Pharmaceuticals Inc
ARNA / Arena Pharmaceuticals Inc Call
ARNA / Arena Pharmaceuticals Inc Put
ECYT / Endocyte, Inc. Put
PCYC / Pharmacyclics Put
ANTH / Anthera Pharmaceuticals, Inc.
ACRX / Talphera, Inc. Call
INCY / Incyte Corporation Call
CLSN / Imunon Inc Put
CLDX / Celldex Therapeutics, Inc.
CLDX / Celldex Therapeutics, Inc. Call
CLDX / Celldex Therapeutics, Inc. Put
MDVN / Medivation, Inc. Call
MDVN / Medivation, Inc. Put
SLS / SELLAS Life Sciences Group, Inc. Call
INCY / Incyte Corporation Put
ACHV / Achieve Life Sciences, Inc.
ACHV / Achieve Life Sciences, Inc. Put
AMPE / Ampio Pharmaceuticals, Inc.
AMPE / Ampio Pharmaceuticals, Inc. Put
ARROWHEAD RESEARCH CORP / Call (042797909)
ARROWHEAD RESEARCH CORP / Put (042797959)
PATI / Patriot Transportation Holding, Inc.
CHTP / Chelsea Therapeutics International, Ltd.
CHELSEA THERAPEUTICS INTERNATIONAL LTD / Put (163428955)
DNDN / Put
WINT / Windtree Therapeutics, Inc.
DYAX / Dyax Corp. Call
ENTREMED INC / (29382F202)
HALO / Halozyme Therapeutics, Inc. Call
HZNP / Horizon Therapeutics Plc Put
IDIX / Idenix Pharmaceuticals Inc Call
IMUC / EOM Pharmaceuticals Holdings, Inc.
INTERMUNE INC / Call (45884X903)
INTERMUNE INC / Put (45884X953)
KYTH / Kythera Biopharma
LGNXZ / Ligand Pharmaceuticals Incorporated - Equity Right Call
OREX / Orexigen Therapeutics, Inc. Call
PRNAF / Alterity Therapeutics Limited Call
PRTA / Prothena Corporation plc
RMTI / Rockwell Medical, Inc. Put
STAA / STAAR Surgical Company Put
STML / Stemline Therapeutics, Inc.
SGYPW / Synergy Pharmaceuticals, Inc., Warrants
TRGT / Targacept
TRGT / Targacept Call
ABUS / Arbutus Biopharma Corporation
TEVA / Teva Pharmaceutical Industries Limited - Depositary Receipt (Common Stock) Call
TROV / TrovaGene, Inc.
TWTR / Twitter Inc
TWTR / Twitter Inc Put
VENTRUS BIOSCIENCES INC / Put (922822951)
ZGNX / Zogenix Inc
RIGL / Rigel Pharmaceuticals, Inc.
MRTX / Mirati Therapeutics, Inc.
NUPATHE INC / (67059M100)
NUPATHE INC / Put (67059M950)
OCRX / Ocera Therapeutics, Inc.
ACHV / Achieve Life Sciences, Inc. Call
GERN / Geron Corporation
US00448Q2012 / Achillion Pharmaceuticals, Inc.
ECYT / Endocyte, Inc.
SQNM / Sequenom, Inc.
DNDN /
VNDA / Vanda Pharmaceuticals Inc.
AEGR / Aegerion Pharmaceuticals, Inc.
AVNR / Avanir Pharmaceuticals Inc
MDVN / Medivation, Inc.
CASC / Cascadian Therapeutics, Inc.
/ VIVUS, Inc. Call
/ VIVUS, Inc. Put
018490100 / Allergan plc Put
OREX / Orexigen Therapeutics, Inc. Put
SQNM / Sequenom, Inc. Call
SQNM / Sequenom, Inc. Put
CBST / Call
CBST / Put
ECYT / Endocyte, Inc. Call
76028H209 / Repros Therapeutics, Inc. Call
76028H209 / Repros Therapeutics, Inc. Put
ACAD / ACADIA Pharmaceuticals Inc. Call
ACAD / ACADIA Pharmaceuticals Inc. Put
KERX / Keryx Biopharmaceuticals, Inc. Call
KERX / Keryx Biopharmaceuticals, Inc. Put
AEGR / Aegerion Pharmaceuticals, Inc. Call
AEGR / Aegerion Pharmaceuticals, Inc. Put
BMYMP / Bristol-Myers Squibb Company - Preferred Security Call
BMYMP / Bristol-Myers Squibb Company - Preferred Security Put
EXAS / Exact Sciences Corporation Call
ONTY / Oncothyreon, Inc. Call
US60877T1007 / Momenta Pharmaceuticals, Inc. Call
GSK / GSK plc - Depositary Receipt (Common Stock) Call
GSK / GSK plc - Depositary Receipt (Common Stock) Put
INVA / Innoviva, Inc. Call
EW / Edwards Lifesciences Corporation Call
AVNR / Avanir Pharmaceuticals Inc Put
ALXA / Alexza Pharmaceuticals, Inc. Call
MLNT / Melinta Therapeutics, Inc.
ZIOP / Alaunos Therapeutics Inc Call
ZIOP / Alaunos Therapeutics Inc Put
GERN / Geron Corporation Put
02318X100 / Ambit Biosciences Corp
ARCT / Arcturus Therapeutics Holdings Inc.
TRANSCEPT PHARMACEUTICALS INC / (89354M956)
AASTROM BIOSCIENCES INC / (00253U305)
CORONADO BIOSCIENCES INC / Call (21976U909)
CORONADO BIOSCIENCES INC / Put (21976U959)
ELAN CORPORATION PLC / ADR Call (284131908)
ISHARES MSCI JAPAN ETF / ETF Put (464286958)
TRANSCEPT PHARMACEUTICALS INC / Put (89354M956)
AASTROM BIOSCIENCES INC / (00253U305)
ARROWHEAD RESEARCH CORP / (042797909)
CORONADO BIOSCIENCES INC / (21976U909)
CORONADO BIOSCIENCES INC / (21976U959)
ELAN CORPORATION PLC / ADR (284131908)
ZIOP / Alaunos Therapeutics Inc
INTERMUNE INC / (45884X903)
INTERMUNE INC / (45884X953)
ISHARES MSCI JAPAN ETF / ETF (464286958)
NUPATHE INC / (67059M950)
/ VIVUS, Inc.
OREX / Orexigen Therapeutics, Inc.
SCON / Superconductor Technologies Inc.
WCG / Wellcare Health Plans, Inc.
VNDA / Vanda Pharmaceuticals Inc. Call
VNDA / Vanda Pharmaceuticals Inc. Put
CYBX / Cyberonics, Inc.
CYBX / Cyberonics, Inc. Put
GSK / GSK plc - Depositary Receipt (Common Stock)
UNXLQ / Uni-Pixel, Inc.
UNXLQ / Uni-Pixel, Inc. Call
CBST /
TMP / Tompkins Financial Corporation
ONXX / Onyx Pharmaceuticals Inc
PCYC / Pharmacyclics Call
ASTX / Investment Managers Series Trust II - Tradr 2X Long ASTS Daily ETF
KERX / Keryx Biopharmaceuticals, Inc.
ARAY / Accuray Incorporated
ARAY / Accuray Incorporated Call
ARAY / Accuray Incorporated Put
BMRN / BioMarin Pharmaceutical Inc. Call
76028H209 / Repros Therapeutics, Inc.
TVIA / TerraVia Holdings, Inc.
BB / BlackBerry Limited
TVIA / TerraVia Holdings, Inc. Put
ONYX / Onyx Acquisition Co. I
ONYX / Onyx Acquisition Co. I Call
ASTEX / American Funds Short-Term Tax-Exempt Bond Fund - American Funds Short-Term Tax-Exempt Bond Fund Class A
ASTEX / American Funds Short-Term Tax-Exempt Bond Fund - American Funds Short-Term Tax-Exempt Bond Fund Class A Call
ASTEX / American Funds Short-Term Tax-Exempt Bond Fund - American Funds Short-Term Tax-Exempt Bond Fund Class A Put
BB / BlackBerry Limited Put
ACOR / Acorda Therapeutics, Inc.
OPK / OPKO Health, Inc.
US60877T1007 / Momenta Pharmaceuticals, Inc.
INVA / Innoviva, Inc.
BMYMP / Bristol-Myers Squibb Company - Preferred Security
NSPH / Nanosphere, Inc.
ONTY / Oncothyreon, Inc.
HOLX / Hologic, Inc.
HOLX / Hologic, Inc. Call
BCRX / BioCryst Pharmaceuticals, Inc.
CCXI / ChemoCentryx Inc
CCXI / ChemoCentryx Inc Put
MDCO / Medicines Company
ALXA / Alexza Pharmaceuticals, Inc.
MDCO / Medicines Company Call
IHRMF / iShares Public Limited Company - iShares MSCI Japan UCITS ETF USD (Dist)
EW / Edwards Lifesciences Corporation
EXAS / Exact Sciences Corporation
EXAS / Exact Sciences Corporation Put
REGN / Regeneron Pharmaceuticals, Inc.
REGN / Regeneron Pharmaceuticals, Inc. Call
REGN / Regeneron Pharmaceuticals, Inc. Put
BIIB / Biogen Inc.
BIIB / Biogen Inc. Put
MDGL / Madrigal Pharmaceuticals, Inc.
ACAD / ACADIA Pharmaceuticals Inc.
HGEN / Humanigen, Inc.
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock) Put
VRTX / Vertex Pharmaceuticals Incorporated
SRPT / Sarepta Therapeutics, Inc. Call
VRTX / Vertex Pharmaceuticals Incorporated Put
SRPT / Sarepta Therapeutics, Inc.
SRPT / Sarepta Therapeutics, Inc. Put
DYAX / Dyax Corp.
IONS / Ionis Pharmaceuticals, Inc.
SSKN / STRATA Skin Sciences, Inc.
IONS / Ionis Pharmaceuticals, Inc. Put
IONS / Ionis Pharmaceuticals, Inc. Call
US0153511094 / Alexion Pharmaceuticals, Inc.
MSTX / Tidal Trust II - Defiance Daily Target 2X Long MSTR ETF
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock)
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock) Call
ACOR / Acorda Therapeutics, Inc. Call
ATHX / Athersys, Inc. Call
ATHX / Athersys, Inc.
CELG / Celgene Corp.
CELG / Celgene Corp. Call
CELG / Celgene Corp. Put
NVAX / Novavax, Inc. Put
FCSC / Fibrocell Science Inc.
AGEN / Agenus Inc.
AGEN / Agenus Inc. Call
AMRN / Amarin Corporation plc - Depositary Receipt (Common Stock)
AMRN / Amarin Corporation plc - Depositary Receipt (Common Stock) Call
AMRN / Amarin Corporation plc - Depositary Receipt (Common Stock) Put
VIRX / Viracta Therapeutics, Inc.
MRK / Merck & Co., Inc.
BAX / Baxter International Inc. Call
WCG / Wellcare Health Plans, Inc. Call
IMUC / EOM Pharmaceuticals Holdings, Inc. Put
ARIA / ARIAD Pharmaceuticals, Inc. Call
ARIA / ARIAD Pharmaceuticals, Inc. Put
ARIA / ARIAD Pharmaceuticals, Inc.
VRTX / Vertex Pharmaceuticals Incorporated Call
MEIP / MEI Pharma, Inc.
MEIP / MEI Pharma, Inc. Call
018490100 / Allergan plc
018490100 / Allergan plc Call
XOMA / XOMA Royalty Corporation
XOMA / XOMA Royalty Corporation Put
INFI / Infinity Pharmaceuticals Inc.
INFI / Infinity Pharmaceuticals Inc. Call
SLS / SELLAS Life Sciences Group, Inc.
MBOT / Microbot Medical Inc.
INCY / Incyte Corporation
AVEO / AVEO Pharmaceuticals Inc
CYTK / Cytokinetics, Incorporated Call
BCRX / BioCryst Pharmaceuticals, Inc. Call
BCRX / BioCryst Pharmaceuticals, Inc. Put
BAX / Baxter International Inc.
PBYI / Puma Biotechnology, Inc. Call
GILD / Gilead Sciences, Inc. Put
BIIB / Biogen Inc. Call
CLVS / Clovis Oncology Inc Call
ADMP / Adamis Pharmaceuticals Corp
ABBV / AbbVie Inc. Call
GILD / Gilead Sciences, Inc. Call
PSTI / Pluristem Therapeutics Inc Put
NVAX / Novavax, Inc.
PBF / PBF Energy Inc.
PBF / PBF Energy Inc. Call
GILD / Gilead Sciences, Inc.
OPK / OPKO Health, Inc. Call
OPK / OPKO Health, Inc. Put
LXRX / Lexicon Pharmaceuticals, Inc.
TENX / Tenax Therapeutics, Inc.
ACRX / Talphera, Inc.
US00448Q2012 / Achillion Pharmaceuticals, Inc. Call
US00448Q2012 / Achillion Pharmaceuticals, Inc. Put
BLUE / bluebird bio, Inc.
PSTI / Pluristem Therapeutics Inc
MDGL / Madrigal Pharmaceuticals, Inc. Put
MDGL / Madrigal Pharmaceuticals, Inc. Call
MNKD / MannKind Corporation
MNKD / MannKind Corporation Call
MNKD / MannKind Corporation Put
VIRX / Viracta Therapeutics, Inc. Call
GEVO / Gevo, Inc.
VIRX / Viracta Therapeutics, Inc. Put
SLS / SELLAS Life Sciences Group, Inc. Put
OCUP / Opus Genetics, Inc.
EDAP / EDAP TMS S.A. - Depositary Receipt (Common Stock)
NBIX / Neurocrine Biosciences, Inc. Call
NBIX / Neurocrine Biosciences, Inc.
NWBO / Northwest Biotherapeutics, Inc. Call
NWBO / Northwest Biotherapeutics, Inc. Put
DVAX / Dynavax Technologies Corporation
ONCY / Oncolytics Biotech Inc.
ONCY / Oncolytics Biotech Inc. Call
TPST / Tempest Therapeutics, Inc.
CVM / CEL-SCI Corporation
OTLC / Oncotelic Therapeutics, Inc.
CLSN / Imunon Inc Call
CLSN / Imunon Inc
SRNE / Sorrento Therapeutics, Inc.
ISR / Perspective Therapeutics Inc
SEEL / Seelos Therapeutics, Inc. Put
SEEL / Seelos Therapeutics, Inc.
ACRX / Talphera, Inc.
LLY / Eli Lilly and Company
SPY / SPDR S&P 500 ETF Put
SPY / SPDR S&P 500 ETF Call
LLY / Eli Lilly and Company Put
OEF / iShares Trust - iShares S&P 100 ETF Put
OEF / iShares Trust - iShares S&P 100 ETF
SPY / SPDR S&P 500 ETF
OEF / iShares Trust - iShares S&P 100 ETF Call