ECYT / Endocyte, Inc. - Pengajuan SECLaporan Tahunan, Pernyataan Proksi

Endocyte, Inc.
US ˙ NASDAQ
HINDI NA ACTIVE ANG SIMBONG ITO

Mga Batayang Estadistika
CIK 1235007
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Endocyte, Inc.
SEC Filings (Chronological Order)
Halaman ini menyediakan daftar lengkap dan kronologis dari Pengajuan SEC, tidak termasuk pengajuan kepemilikan yang kami sediakan di tempat lain.
February 14, 2019 SC 13G/A

ECYT / Endocyte, Inc. / Partner Fund Management, L.P. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) Information Statement Pursuant to Rules 13d-1 and 13d-2 Under the Securities Exchange Act of 1934 (Amendment No. 2 )* Endocyte, Inc. (Name of Issuer) Common stock, par value $0.001 per share (Title of Class of Securities) 29269A102 (CUSIP Number) December 31, 2018 Date of Event Which Requires Filing

December 31, 2018 15-12B

ECYT / Endocyte, Inc. 15-12B

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 15 CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER SECTION 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR SUSPENSION OF DUTY TO FILE REPORTS UNDER SECTIONS 13 AND 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. Commission File Number 001-35050 Endocyte, Inc. (Exact name of registrant as specified in its chart

December 21, 2018 S-8 POS

ECYT / Endocyte, Inc. S-8 POS

As filed with the Securities and Exchange Commission on December 21, 2018 Registration No.

December 21, 2018 S-8 POS

ECYT / Endocyte, Inc. S-8 POS

As filed with the Securities and Exchange Commission on December 21, 2018 Registration No.

December 21, 2018 S-8 POS

ECYT / Endocyte, Inc. S-8 POS

As filed with the Securities and Exchange Commission on December 21, 2018 Registration No.

December 21, 2018 S-8 POS

ECYT / Endocyte, Inc. S-8 POS

As filed with the Securities and Exchange Commission on December 21, 2018 Registration No.

December 21, 2018 S-8 POS

ECYT / Endocyte, Inc. S-8 POS

As filed with the Securities and Exchange Commission on December 21, 2018 Registration No.

December 21, 2018 S-8 POS

ECYT / Endocyte, Inc. S-8 POS

As filed with the Securities and Exchange Commission on December 21, 2018 Registration No.

December 21, 2018 S-8 POS

ECYT / Endocyte, Inc. S-8 POS

As filed with the Securities and Exchange Commission on December 21, 2018 Registration No.

December 21, 2018 POSASR

ECYT / Endocyte, Inc. POSASR

As filed with the Securities and Exchange Commission on December 21, 2018 Registration No.

December 21, 2018 8-K

Changes in Control of Registrant, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Material Modification to Rights of Security Holders, Completion of Acquisition or Disposition of Assets

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): December 17, 2018 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of inc

December 21, 2018 EX-3.1

Amended and Restated Certificate of Incorporation of Endocyte, Inc., effective December 21, 2018

Exhibit 3.1 Amended and Restated Certificate of Incorporation of Endocyte, Inc. 1. The name of the corporation is “Endocyte, Inc.” (the “Corporation”). 2. The address of the Corporation’s registered office is Corporation Service Company, 251 Little Falls Drive, New Castle County Wilmington, Delaware 19808. The Corporation Service Company is the Corporation’s registered agent at that address. 3. Th

December 21, 2018 EX-3.2

Amended and Restated Bylaws of Endocyte, Inc., effective December 21, 2018

Exhibit 3.2 BY-LAWS OF ENDOCYTE, INC. (the “Corporation”) 1. MEETINGS OF STOCKHOLDERS. 1.1 Annual Meeting. The annual meeting of stockholders shall be held on such date and at such time as shall be designated from time to time by the board of directors (the “Board”) and stated in the notice of the meeting or waiver of notice thereof; except that no annual meeting need be held if all actions, inclu

December 21, 2018 EX-10.2

Form of Amendment to Change in Control and Severance Agreement

Exhibit 10.2 AMENDMENT TO CHANGE IN CONTROL AND SEVERANCE AGREEMENT This Amendment to Change in Control and Severance Agreement (the “Amendment”) is made and entered into by and between Endocyte, Inc., a Delaware corporation (the “Company”), and (“Employee”), effective , 2018, to amend the Change in Control and Severance Agreement (“Agreement”) made and entered into effective as of , 20 , by and b

December 20, 2018 POS AM

ECYT / Endocyte, Inc. POS AM

As filed with the Securities and Exchange Commission on December 20, 2018 Registration No.

December 17, 2018 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): December 14, 2018 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of inc

December 12, 2018 DEFA14A

ECYT / Endocyte, Inc. DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION (Rule 14a-101) Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted b

December 3, 2018 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): November 30, 2018 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of inc

November 16, 2018 DEFM14A

ECYT / Endocyte, Inc. DEFM14A

Use these links to rapidly review the document TABLE OF CONTENTS TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

November 8, 2018 DEFA14A

ECYT / Endocyte, Inc. DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION (Rule 14a-101) Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted b

November 8, 2018 10-Q

ECYT / Endocyte, Inc. 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2018 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE, INC. (E

November 7, 2018 EX-99.1

Endocyte Provides Third Quarter 2018 Financial Results and Operational Update -Entered into agreement and plan of merger with Novartis AG for $2.1Billion-

Exhibit 99.1 Investor Contact: Michael Schaffzin, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Provides Third Quarter 2018 Financial Results and Operational Update -Entered into agreement and plan of merger with Novartis AG for $2.1Billion- WEST LAFAYETTE, Ind., November 7th, 2018 (GLOBE NEWSWIRE) - Endocyte, Inc. (Nasdaq:ECYT), a biopharmaceutical comp

November 7, 2018 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): November 7, 2018 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of inco

November 6, 2018 DFAN14A

NVS / Novartis AG DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant o Filed by a Party other than the Registrant x Check the appropriate box: o Preliminary Proxy Statement o Confide

November 5, 2018 DFAN14A

NVS / Novartis AG DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant o Filed by a Party other than the Registrant x Check the appropriate box: o Preliminary Proxy Statement o Confide

November 1, 2018 EX-99.1

JOINT FILING AGREEMENT

Exhibit 99.1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k), as promulgated under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them a Statement on Schedule 13D (including amendments thereto) with regard to the common stock of Endocyte, Inc. and further agree that this Joint Filing Agreement be included as an Exhibi

November 1, 2018 SC 13D

ECYT / Endocyte, Inc. / Magnetar Financial LLC - SC 13D Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. )* ENDOCYTE, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 29269A102 (CUSIP Number of Class of Securities) Alec N. Litowitz Magnetar Capital LLC 1603 Orrington Ave. Evanston, Illinois 60201 (847) 905-4400 (Name

October 31, 2018 PREM14A

ECYT / Endocyte, Inc. PREM14A

Use these links to rapidly review the document TABLE OF CONTENTS TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

October 19, 2018 DEFA14A

ECYT / Endocyte, Inc. DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION (Rule 14a-101) Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted b

October 18, 2018 DFAN14A

NVS / Novartis AG DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant o Filed by a Party other than the Registrant x Check the appropriate box: o Preliminary Proxy Statement o Confide

October 18, 2018 DFAN14A

NVS / Novartis AG DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant o Filed by a Party other than the Registrant x Check the appropriate box: o Preliminary Proxy Statement o Confide

October 18, 2018 DFAN14A

NVS / Novartis AG DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant o Filed by a Party other than the Registrant x Check the appropriate box: o Preliminary Proxy Statement o Confide

October 18, 2018 DFAN14A

NVS / Novartis AG DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant o Filed by a Party other than the Registrant x Check the appropriate box: o Preliminary Proxy Statement o Confide

October 18, 2018 DEFA14A

ECYT / Endocyte, Inc. DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION (Rule 14a-101) Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted b

October 18, 2018 EX-3.1

Amended and Restated Bylaws of Endocyte, Inc., effective October 17, 2018

Exhibit 3.1 AMENDED AND RESTATED BYLAWS OF ENDOCYTE, INC. (as amended and restated effective as of October 17, 2018) TABLE OF CONTENTS Page ARTICLE I — CORPORATE OFFICES 1 1.1 REGISTERED OFFICE 1 1.2 OTHER OFFICES 1 ARTICLE II — MEETINGS OF STOCKHOLDERS 1 2.1 PLACE OF MEETINGS 1 2.2 ANNUAL MEETING 1 2.3 SPECIAL MEETING 1 2.4 ADVANCE NOTICE PROCEDURES 2 2.5 NOTICE OF STOCKHOLDERS’ MEETINGS 6 2.6 QU

October 18, 2018 EX-2.1

Agreement and Plan of Merger, dated as of October 17, 2018, among Novartis AG, Edinburgh Merger Corporation and Endocyte, Inc. (incorporated by reference to Exhibit 2.1 to the Current Report on Form 8-K filed on October 18, 2018)

Exhibit 2.1 AGREEMENT AND PLAN OF MERGER dated as of October 17, 2018, among NOVARTIS AG, EDINBURGH MERGER CORPORATION and ENDOCYTE, INC. TABLE OF CONTENTS Page ARTICLE I The Merger SECTION 1.01. The Merger 2 SECTION 1.02. Closing 2 SECTION 1.03. Effective Time 2 SECTION 1.04. Effects of Merger 2 SECTION 1.05. Certificate of Incorporation and Bylaws 2 SECTION 1.06. Directors and Officers 3 ARTICLE

October 18, 2018 EX-99.1

Endocyte Enters Into Agreement to be Acquired by Novartis AG for $2.1 Billion Novartis to acquire Endocyte for $24 per fully diluted share in cash PSMA-617 to enhance Novartis’ industry-leading radio-ligand therapy platform

Exhibit 99.1 NEWS RELEASE Endocyte Enters Into Agreement to be Acquired by Novartis AG for $2.1 Billion Novartis to acquire Endocyte for $24 per fully diluted share in cash PSMA-617 to enhance Novartis’ industry-leading radio-ligand therapy platform WEST LAFAYETTE, Ind., October 18, 2018 (GLOBE NEWSWIRE) — Endocyte, Inc. (Nasdaq:ECYT), a biopharmaceutical company developing targeted therapeutics f

October 18, 2018 8-K

Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): October 17, 2018 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of inco

October 18, 2018 EX-3.1

Amended and Restated Bylaws of Endocyte, Inc., effective October 17, 2018

Exhibit 3.1 AMENDED AND RESTATED BYLAWS OF ENDOCYTE, INC. (as amended and restated effective as of October 17, 2018) TABLE OF CONTENTS Page ARTICLE I — CORPORATE OFFICES 1 1.1 REGISTERED OFFICE 1 1.2 OTHER OFFICES 1 ARTICLE II — MEETINGS OF STOCKHOLDERS 1 2.1 PLACE OF MEETINGS 1 2.2 ANNUAL MEETING 1 2.3 SPECIAL MEETING 1 2.4 ADVANCE NOTICE PROCEDURES 2 2.5 NOTICE OF STOCKHOLDERS’ MEETINGS 6 2.6 QU

October 18, 2018 DEFA14A

ECYT / Endocyte, Inc. 8-K

DEFA14A 1 a18-3691018k.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): October 17, 2018 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Comm

October 18, 2018 EX-2.1

Agreement and Plan of Merger, dated as of October 17, 2018, by and among Novartis AG, Edinburgh Merger Corporation and Endocyte, Inc.

Exhibit 2.1 AGREEMENT AND PLAN OF MERGER dated as of October 17, 2018, among NOVARTIS AG, EDINBURGH MERGER CORPORATION and ENDOCYTE, INC. TABLE OF CONTENTS Page ARTICLE I The Merger SECTION 1.01. The Merger 2 SECTION 1.02. Closing 2 SECTION 1.03. Effective Time 2 SECTION 1.04. Effects of Merger 2 SECTION 1.05. Certificate of Incorporation and Bylaws 2 SECTION 1.06. Directors and Officers 3 ARTICLE

October 18, 2018 EX-99.1

Press Release, dated October 18, 2018

Exhibit 99.1 NEWS RELEASE Endocyte Enters Into Agreement to be Acquired by Novartis AG for $2.1 Billion Novartis to acquire Endocyte for $24 per fully diluted share in cash PSMA-617 to enhance Novartis’ industry-leading radio-ligand therapy platform WEST LAFAYETTE, Ind., October 18, 2018 (GLOBE NEWSWIRE) — Endocyte, Inc. (Nasdaq:ECYT), a biopharmaceutical company developing targeted therapeutics f

September 12, 2018 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 11, 2018 ENDOCYTE, INC. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction of (Commission (I.R.S. Employer in

September 12, 2018 EX-1.1

Underwriting Agreement, dated as of September 11, 2018, by and among the Company and Jefferies LLC, Wells Fargo Securities, LLC, and RBC Capital Markets, LLC, as representatives of the several underwriters named in Schedule A thereto.

Exhibit 1.1 9,459,460 Shares Endocyte, Inc. UNDERWRITING AGREEMENT September 11, 2018 JEFFERIES LLC WELLS FARGO SECURITIES, LLC RBC CAPITAL MARKETS, LLC As Representatives of the several Underwriters c/o Jefferies LLC 520 Madison Avenue New York, New York 10022 c/o Wells Fargo Securities, LLC 375 Park Avenue, 4th Floor New York, New York 10152 c/o RBC Capital Markets, LLC 200 Vesey Street New York

September 12, 2018 424B5

CALCULATION OF REGISTRATION FEE Title Of Each Class Of Securities To Be Registered Amount To Be Registered(1) Maximum Offering Price Per Security Maximum Aggregate Offering Price Amount Of Registration Fee(2) Common stock, par value $0.001 per share

Use these links to rapidly review the document Table of Contents TABLE OF CONTENTS Filed Pursuant to Rule 424(b)(5) Registration No.

September 10, 2018 424B5

$175,000,000 Common Stock

424B5 1 a2236563z424b5.htm PRELIMINARY PROSPECTUS SUPPLEMENT Use these links to rapidly review the document Table of Contents TABLE OF CONTENTS Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-227261 The information contained in this preliminary prospectus supplement is not complete and may be changed. This preliminary prospectus supplement and the accompanying prospectus ar

September 10, 2018 S-3ASR

ECYT / Endocyte, Inc. REGISTRATION STATEMENT ON FORM S-3ASR

S-3ASR 1 a2236562zs-3asr.htm REGISTRATION STATEMENT ON FORM S-3ASR Use these links to rapidly review the document TABLE OF CONTENTS Table of Contents As filed with the Securities and Exchange Commission on September 10, 2018 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-3 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 ENDOCYTE, INC. (

September 10, 2018 EX-4.7

Form of Senior Indenture

Exhibit 4.7 ENDOCYTE, INC. TO [ ] Trustee INDENTURE Dated as of [ ] Senior Debt Securities Endocyte, Inc. Reconciliation and tie between Trust Indenture Act of 1939 and Indenture, dated as of [ ] Trust Indenture Act Section Indenture Section §310 (a)(1) 609 (a)(2) 609 (a)(3) Not Applicable (a)(4) Not Applicable (a)(5) 609 (b) 608, 610 §311 (a) 613 (b) 613 §312 (a) 701, 702(a) (b) 702(b) (c) 702(c)

September 10, 2018 EX-4.8

Form of Subordinated Indenture

Exhibit 4.8 ENDOCYTE, INC. TO [ ] Trustee INDENTURE Dated as of [ ] Subordinated Debt Securities Endocyte, Inc. Reconciliation and tie between Trust Indenture Act of 1939 and Indenture, dated as of [ ] Trust Indenture Act Section Indenture Section §310(a)(1) 609 (a)(2) 609 (a)(3) Not Applicable (a)(4) Not Applicable (a)(5) 609 (b) 608, 610 §311(a) 613 (b) 613 §312(a) 701, 702(a) (b) 702(b) (c) 702

September 10, 2018 EX-12.1

Computation of Ratio of Earnings to Fixed Charges

Exhibit 12.1 STATEMENT REGARDING COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES (dollars in thousands) Fiscal Year Ended December 31, Six Months Ended June 30, 2013 2014 2015 2016 2017 2018 Fixed Charges Interest expense on indebtedness $ — $ — $ — $ — $ — $ — Non-cash interest expense and other — — — — — — Interest expense on portion of rent expense representative of interest 113 125 106 107 1

September 10, 2018 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

8-K 1 f8-k.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): September 10, 2018 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.

September 10, 2018 EX-99.1

Endocyte Announces FDA Acceptance of Radiographic Progression Free Survival (rPFS) as an Alternative Primary Endpoint of the VISION Trial in Addition to Overall Survival (OS) Demonstrating benefit in rPFS versus control, with no detriment to OS, suff

Exhibit 99.1 Investor Contact: Michael Schaffzin, Stern Investor Relations, Inc., (212) 362-1200 [email protected] NEWS RELEASE Endocyte Announces FDA Acceptance of Radiographic Progression Free Survival (rPFS) as an Alternative Primary Endpoint of the VISION Trial in Addition to Overall Survival (OS) Demonstrating benefit in rPFS versus control, with no detriment to OS, sufficient for full appr

August 1, 2018 EX-10.8

Form of 2010 Equity Incentive Plan Time-Based Restricted Stock Unit Award Agreement (Directors – Annual Grants) (for use after July 18, 2018).

Exhibit 10.8 ENDOCYTE, INC. 2010 EQUITY INCENTIVE PLAN TIME-BASED RESTRICTED STOCK UNIT AWARD AGREEMENT This Award Agreement (“Award Agreement”), dated as of , 20, is by and between Endocyte, Inc., a Delaware corporation (the “Company”), and (“Participant”). Unless otherwise defined herein, the terms defined in the Endocyte, Inc. 2010 Equity Incentive Plan (the “Plan”), shall have the same defined

August 1, 2018 EX-10.6

Form of 2010 Equity Incentive Plan Time-Based Restricted Stock Unit Award Agreement (Directors – Initial Grants) (for use after July 18, 2018).

Exhibit 10.6 ENDOCYTE, INC. 2010 EQUITY INCENTIVE PLAN TIME-BASED RESTRICTED STOCK UNIT AWARD AGREEMENT This Award Agreement (“Award Agreement”), dated as of , 20, is by and between Endocyte, Inc., a Delaware corporation (the “Company”), and (“Participant”). Unless otherwise defined herein, the terms defined in the Endocyte, Inc. 2010 Equity Incentive Plan (the “Plan”), shall have the same defined

August 1, 2018 EX-10.4

Form of 2010 Equity Incentive Plan Time-Based Restricted Stock Unit Award Agreement (Employees) (for use after July 18, 2018).

Exhibit 10.4 ENDOCYTE, INC. 2010 EQUITY INCENTIVE PLAN TIME-BASED RESTRICTED STOCK UNIT AWARD AGREEMENT This Award Agreement (“Award Agreement”), dated as of , 20, is by and between Endocyte, Inc., a Delaware corporation (the “Company”), and (“Participant”). Unless otherwise defined herein, the terms defined in the Endocyte, Inc. 2010 Equity Incentive Plan (the “Plan”), shall have the same defined

August 1, 2018 EX-10.9

Form of 2010 Equity Incentive Plan Stock Option Award Agreement (Directors – Annual Grants) (for use after July 18, 2018).

Exhibit 10.9 ENDOCYTE, INC. 2010 EQUITY INCENTIVE PLAN STOCK OPTION AWARD AGREEMENT This Award Agreement (“Award Agreement”), dated as of , 20, is by and between Endocyte, Inc., a Delaware corporation (the “Company”), and (“Optionee”). Unless otherwise defined herein, the terms defined in the Endocyte, Inc. 2010 Equity Incentive Plan (the “Plan”), shall have the same defined meanings in this Award

August 1, 2018 EX-10.1

Fifth Amendment to Office Lease dated May 29, 2018 between Endocyte, Inc. and Tempus One College Park LLC as successor in interest to Zeller Management Corporation.

Exhibit 10.1 FIFTH AMENDMENT TO OFFICE LEASE THIS FIFTH AMENDMENT TO OFFICE LEASE (this “Amendment”) is made and entered into as of the 29th day of May, 2018, by and between TEMPUS ONE COLLEGE PARK LLC (“Landlord”), as successor in interest to ZELLER MANAGEMENT CORPORATION, as agent for Owner (“Original Landlord”), and ENDOCYTE, INC. (“Tenant”). RECITALS WHEREAS, on May 30, 2008, Original Landlord

August 1, 2018 EX-10.2

Second Amendment of Lease dated June 14, 2018 between Endocyte, Inc. and Purdue Research Foundation.

Exhibit 10.2 PURDUE TECHNOLOGY CENTER 3000 Kent Avenue West Lafayette, Indiana 47906 SECOND AMENDMENT AND EXTENSION OF LEASE THIS SECOND AMENDMENT AND EXTENSION OF LEASE is made this 14th day of June, 2018 by and between PURDUE RESEARCH FOUNDATION (“Landlord”), an Indiana corporation (formed and existing under the Indiana Foundation or Holding Companies Act, Acts of 1921, ch. 246), and ENDOCYTE (“

August 1, 2018 10-Q

ECYT / Endocyte, Inc. 10-Q (Quarterly Report)

10-Q 1 ecyt-20180630x10q.htm 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2018 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file numbe

August 1, 2018 EX-10.7

Form of 2010 Equity Incentive Plan Stock Option Award Agreement (Directors – Initial Grants) (for use after July 18, 2018).

Exhibit 10.7 ENDOCYTE, INC. 2010 EQUITY INCENTIVE PLAN STOCK OPTION AWARD AGREEMENT This Award Agreement (“Award Agreement”), dated as of , 20, is by and between Endocyte, Inc., a Delaware corporation (the “Company”), and (“Optionee”). Unless otherwise defined herein, the terms defined in the Endocyte, Inc. 2010 Equity Incentive Plan (the “Plan”), shall have the same defined meanings in this Award

August 1, 2018 EX-10.5

Form of 2010 Equity Incentive Plan Stock Option Award Agreement (Employees) (for use after July 18, 2018).

Exhibit 10.5 ENDOCYTE, INC. 2010 EQUITY INCENTIVE PLAN STOCK OPTION AWARD AGREEMENT This Award Agreement (“Award Agreement”), dated as of , 20, is by and between Endocyte, Inc., a Delaware corporation (the “Company”), and (“Optionee”). Unless otherwise defined herein, the terms defined in the Endocyte, Inc. 2010 Equity Incentive Plan (the “Plan”), shall have the same defined meanings in this Award

July 31, 2018 EX-99.1

Endocyte Provides Second Quarter 2018 Financial Results and Operational Update -Initiated phase 3 VISION study of 177Lu-PSMA-617 in mCRPC- -Secured commercial supply of no-carrier-added Lutetium-177 through 2035- -Investigational new drug (IND) filin

Exhibit 99.1 Investor Contact: Michael Schaffzin, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Provides Second Quarter 2018 Financial Results and Operational Update -Initiated phase 3 VISION study of 177Lu-PSMA-617 in mCRPC- -Secured commercial supply of no-carrier-added Lutetium-177 through 2035- -Investigational new drug (IND) filing for EC17/CAR T-ce

July 31, 2018 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): July 31, 2018 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of incorpo

July 11, 2018 8-K

Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): July 5, 2018 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of incorpor

July 11, 2018 EX-10.1

Global Supply Agreement between Endocyte, Inc. and ITG Isotope Technologies Garching GmbH (incorporated by reference to Exhibit 10.1 to Current Report on Form 8-K filed July 11, 2018).

Exhibit 10.1 CONFIDENTIAL TREATMENT REQUESTED Portions of this Exhibit have been redacted pursuant to a request for confidential treatment under Rule 24b-2 of the General Rules and Regulations under the Securities Exchange Act of 1934, as amended. Omitted information, marked “[*]” in this Exhibit, has been filed separately with the Securities and Exchange Commission together with such request for

July 11, 2018 EX-99.1

Endocyte and ITM Announce Long-Term Supply Agreement for No-Carrier-Added Lutetium-177 – Strategic Partnership Supports Commercialization Beyond Ongoing Phase 3 VISION Trial of 177Lu-PSMA-617 –

EX-99.1 3 ex-99d1.htm EX-99.1 Exhibit 99.1 NEWS RELEASE Endocyte and ITM Announce Long-Term Supply Agreement for No-Carrier-Added Lutetium-177 – Strategic Partnership Supports Commercialization Beyond Ongoing Phase 3 VISION Trial of 177Lu-PSMA-617 – West Lafayette, IN., and Garching, Germany, Jul. 9, 2018 – Endocyte, Inc. (Nasdaq:ECYT), and ITM Isotopen Technologien München AG (ITM), a specialized

May 9, 2018 10-Q

ECYT / Endocyte, Inc. 10-Q (Quarterly Report)

10-Q 1 ecyt-20180331x10q.htm 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2018 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file numb

May 9, 2018 EX-10.1

Fourth Amendment to Office Lease dated January 26, 2018 between Endocyte, Inc. and Tempus One College Park LLC as successor in interest to Zeller Management Corporation.

EX-10.1 2 ecyt-20180331ex10194b733.htm EX-10.1 Exhibit 10.1 FOURTH AMENDMENT TO OFFICE LEASE THIS FOURTH AMENDMENT TO OFFICE LEASE (this “Amendment”) is made and entered into as of the 26th day of January, 2018, by and between TEMPUS ONE COLLEGE PARK LLC, an Arkansas limited liability company (“Landlord”), as successor in interest to ZELLER MANAGEMENT CORPORATION, as agent for Owner (“Original Lan

May 9, 2018 EX-99.1

Endocyte Provides First Quarter 2018 Financial Results and Operational Update – Recently Updated Phase 2 Data on 177Lu-PSMA-617 Published in The Lancet Oncology Favorable to Preliminary Data Presented at 2017 ESMO Congress – – Positive End of Phase 2

Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Provides First Quarter 2018 Financial Results and Operational Update – Recently Updated Phase 2 Data on 177Lu-PSMA-617 Published in The Lancet Oncology Favorable to Preliminary Data Presented at 2017 ESMO Congress – – Positive End of Phase 2 FDA Meeting Set Stage for

May 9, 2018 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 3, 2018 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of incorpora

March 23, 2018 DEFA14A

ECYT / Endocyte, Inc. DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☑ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a‑6(e)(2)) ☐ Defin

March 23, 2018 DEF 14A

ECYT / Endocyte, Inc. DEF 14A

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☑ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14

March 15, 2018 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 12, 2018 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of incorp

March 15, 2018 EX-99.1

Endocyte Nominates Dawn Svoronos for Election to Its Board of Directors and Announces Other Board Developments –Dawn Svoronos, Former President of Merck’s Europe/Canada Region, Brings Significant Commercial Leadership and Board Experience –

Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Nominates Dawn Svoronos for Election to Its Board of Directors and Announces Other Board Developments –Dawn Svoronos, Former President of Merck’s Europe/Canada Region, Brings Significant Commercial Leadership and Board Experience – West Lafayette, Ind., Mar. 15, 2018

March 12, 2018 SC 13G

ECYT / Endocyte, Inc. / Venrock Healthcare Capital Partners Ii, L.p. - SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Endocyte, Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities) 29269A102 (CUSIP Number) February 28, 2018 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to wh

March 2, 2018 8-K

Current Report

8-K 1 f8-k.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): February 26, 2018 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R

March 2, 2018 EX-99.1

Endocyte Appoints Patrick Machado, J.D. to Its Board of Directors –Patrick Machado, Co-founder and Former Chief Business and Financial Officer of Medivation, Brings Significant Experience in Building Value in the Prostate Cancer Space –

EX-99.1 2 ex-99d1.htm EX-99.1 Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Appoints Patrick Machado, J.D. to Its Board of Directors –Patrick Machado, Co-founder and Former Chief Business and Financial Officer of Medivation, Brings Significant Experience in Building Value in the Prostate Cancer Space – West Lafay

March 1, 2018 SC 13G

ECYT / Endocyte, Inc. / Moll Peter - PETER MOLL 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. ) Endocyte, Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities) 29269A102 (CUSIP Number) September 29, 2017 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to wh

February 28, 2018 S-8 POS

ECYT / Endocyte, Inc. S-8 POS

ecytS8POS As filed with the Securities and Exchange Commission on February 28, 2018 Registration No.

February 28, 2018 S-8

ECYT / Endocyte, Inc. S-8

S-8 1 s-8.htm S-8 As filed with the Securities and Exchange Commission on February 28, 2018 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 ENDOCYTE, INC. (Exact name of registrant as specified in its charter) Delaware 35-1969-140 (State or other jurisdiction of (I.R.S. Employer incorpora

February 28, 2018 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

8-K 1 a18-711038k.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 28, 2018 ENDOCYTE, INC. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction of (Commi

February 28, 2018 EX-1.1

Underwriting Agreement, dated as of February 28, 2018, by and among the Company and Jefferies LLC, Wells Fargo Securities, LLC, and Deutsche Bank Securities Inc., as representatives of the several underwriters named in Schedule A thereto.

EX-1.1 2 a18-71103ex1d1.htm EX-1.1 Exhibit 1.1 17,857,143 Endocyte, Inc. UNDERWRITING AGREEMENT February 28, 2018 JEFFERIES LLC WELLS FARGO SECURITIES, LLC DEUTSCHE BANK SECURITIES INC. As Representatives of the several Underwriters c/o Jefferies LLC 520 Madison Avenue New York, New York 10022 c/o Wells Fargo Securities, LLC 375 Park Avenue, 4th Floor New York, New York 10152 c/o Deutsche Bank Sec

February 28, 2018 424B5

17,857,143 Shares Common Stock

Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-220920 PROSPECTUS SUPPLEMENT (To Prospectus dated October 24, 2017) 17,857,143 Shares Common Stock We are offering 17,857,143 shares of our common stock pursuant to this prospectus supplement and the accompanying prospectus. Our common stock is listed on the Nasdaq Global Market under the symbol "ECYT". On February 27, 2018, t

February 28, 2018 424B5

Shares Common Stock

Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-220920 The information contained in this preliminary prospectus supplement is not complete and may be changed. This preliminary prospectus supplement and the accompanying prospectus are part of an effective registration statement filed with the Securities and Exchange Commission. This preliminary prospectus supplement and the

February 27, 2018 EX-10.19

Amendments #9 and #10 to the Master License Agreement effective July 1, 2013 between Endocyte, Inc. and Purdue Research Foundation, as amended.

Exhibit 10.19 CONFIDENTIAL TREATMENT REQUESTED Portions of this Exhibit have been redacted pursuant to a request for confidential treatment under Rule 24b-2 of the General Rules and Regulations under the Securities Exchange Act of 1934, as amended. Omitted information, marked “[*]” in this Exhibit, has been filed separately with the Securities and Exchange Commission together with such request for

February 27, 2018 EX-10.22

First Amendment of lease dated November 10, 2017 between Endocyte, Inc. and Purdue Research Foundation.

EX-10.22 5 ecyt-20171231ex102216d99.htm EX-10.22 Exhibit 10.22 FIRST AMENDMENT OF LEASE AGREEMENT THIS AGREEMENT is made and entered into this 10th day of November, 2017, by and between PURDUE RESEARCH FOUNDATION , an Indiana corporation (formed and existing under the Indiana Foundation or Holding Companies Act, Acts of 1921, ch. 246), (“Landlord”), and ENDOCYTE (“Tenant”). In consideration of the

February 27, 2018 EX-10.16

Amendment #3 to the Exclusive License Agreement effective March 1, 2010 between Endocyte, Inc. and Purdue Research Foundation, as amended.

Exhibit 10.16 CONFIDENTIAL TREATMENT REQUESTED Portions of this Exhibit have been redacted pursuant to a request for confidential treatment under Rule 24b-2 of the General Rules and Regulations under the Securities Exchange Act of 1934, as amended. Omitted information, marked “[*]” in this Exhibit, has been filed separately with the Securities and Exchange Commission together with such request for

February 27, 2018 10-K

ECYT / Endocyte, Inc. 10-K (Annual Report)

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-K ☑ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2017 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE

February 27, 2018 EX-10.26

chedule of Terms for Change in Control and Severance Agreements with Executive Officers

Exhibit 10.26 ENDOCYTE, INC. SCHEDULE OF TERMS FOR CHANGE IN CONTROL AND SEVERANCE AGREEMENTS WITH EXECUTIVE OFFICERS February 2018 Termination without Cause or Resignation for Good Reason, prior to a Change in Control or after 12 months following a Change in Control Termination without Cause or Resignation for Good Reason, within 12 months following a Change in Control Name of Executive Officer D

February 27, 2018 EX-10.13

Amendment #20 to the Amended and Restated Exclusive License Agreement dated October 21, 1998 between Endocyte, Inc. and Purdue Research Foundation, as amended.

Exhibit 10.13 CONFIDENTIAL TREATMENT REQUESTED Portions of this Exhibit have been redacted pursuant to a request for confidential treatment under Rule 24b-2 of the General Rules and Regulations under the Securities Exchange Act of 1934, as amended. Omitted information, marked “[*]” in this Exhibit, has been filed separately with the Securities and Exchange Commission together with such request for

February 26, 2018 8-K

Current Report

ecytCurrentFolio8K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

February 26, 2018 EX-99.1

Endocyte Announces Phase 3 VISION Trial and Provides Update on Corporate Strategy and Reports Fourth Quarter and Year End 2017 Financial Results –Phase 3 VISION Trial Design Finalized for 177Lu-PSMA-617 Following Successful End of Phase 2 Meeting wit

ecytEx991 Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Announces Phase 3 VISION Trial and Provides Update on Corporate Strategy and Reports Fourth Quarter and Year End 2017 Financial Results ?Phase 3 VISION Trial Design Finalized for 177Lu-PSMA-617 Following Successful End of Phase 2 Meeting with the FDA ? ?Anno

February 14, 2018 SC 13G

ECYT / Endocyte, Inc. / RA Capital Management, LLC - SC 13G Passive Investment

SC 13G 1 tv485684sc13g.htm SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* ENDOCYTE, INC. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 29269A102 (CUSIP Number) December 31, 2017 (Date of Event Which Requires Filing of this Statement) Check the appropri

February 14, 2018 SC 13G/A

ECYT / Endocyte, Inc. / Partner Fund Management, L.P. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) Information Statement Pursuant to Rules 13d-1 and 13d-2 Under the Securities Exchange Act of 1934 (Amendment No. 1 )* Endocyte, Inc. (Name of Issuer) Common stock, par value $0.001 per share (Title of Class of Securities) 29269A102 (CUSIP Number) December 31, 2017 Date of Event Which Requires Filing

January 19, 2018 SC 13G/A

ECYT / Endocyte, Inc. / Pension Fund of the Christian Church (Disciples of Christ) Inc - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 2) Endocyte, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title or Class of Securities) 29269A102 (CUSIP Number) December 31, 2017 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pu

November 16, 2017 SC 13G

ECYT / Endocyte, Inc. / Partner Fund Management, L.P. - SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) Information Statement Pursuant to Rules 13d-1 and 13d-2 Under the Securities Exchange Act of 1934 (Amendment No. )* Endocyte, Inc. (Name of Issuer) Common stock, par value $0.001 per share (Title of Class of Securities) 29269A102 (CUSIP Number) November 6, 2017 Date of Event Which Requires Filing of

November 16, 2017 EX-99.1

JOINT FILING AGREEMENT

EXHIBIT 99.1 JOINT FILING AGREEMENT The undersigned hereby agree that the Statement on Schedule 13G filed herewith (and any amendments thereto), relating to the common stock of Endocyte, Inc., a Delaware corporation, is being filed jointly with the Securities and Exchange Commission pursuant to Rule 13d-1(c) under the Securities Exchange Act of 1934, as amended, on behalf of each of the undersigne

November 7, 2017 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2017 ☐ TRANSITION REPORT PURSUANT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2017 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE, INC. (E

November 6, 2017 8-K

Current Report

ecytCurrentFolio8K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

November 6, 2017 EX-99.1

Endocyte Reports Third Quarter Financial Results - Plans to Initiate Phase 3 Registration for 177Lu-PSMA-617 Accelerated by Radiomedix Agreement to Transfer Active U.S. Investigational New Drug Application (IND) to Endocyte - - The University of Sydn

ecytEx991 Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Reports Third Quarter Financial Results - Plans to Initiate Phase 3 Registration for 177Lu-PSMA-617 Accelerated by Radiomedix Agreement to Transfer Active U.S. Investigational New Drug Application (IND) to Endocyte - - The University of Sydney and ANZUP Canc

October 20, 2017 CORRESP

ECYT / Endocyte, Inc. ESP

ENDOCYTE, INC. 3000 Kent Avenue, Suite A1-100 West Lafayette, IN 47906 October 20, 2017 VIA EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: Endocyte, Inc. Registration Statement on Form S-3 File No. 333-220920 Acceleration Request Requested Date: October 24, 2017 Requested Time: 5:00 p.m. Eastern Time Ladies and Gentlemen: Purs

October 12, 2017 EX-12.1

Computation of Ratios of Earnings to Fixed Charges

Exhibit 12.1 STATEMENT REGARDING COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES (dollars in thousands) Fiscal Year Ended December 31, Six Months Ended June 30, 2012 2013 2014 2015 2016 2017 Fixed Charges: Interest expense on indebtedness $ 555 $ — $ — $ — $ — $ — Non-cash interest expense and other 74 — — — — — Interest expense on portion of rent expense representative of interest 74 113 125 10

October 12, 2017 S-3

As filed with the Securities and Exchange Commission on October 12, 2017

S-3 1 s-3.htm S-3 Table of Contents As filed with the Securities and Exchange Commission on October 12, 2017 Registration No. 333‑ UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S‑3 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 ENDOCYTE, INC. (Exact name of registrant as specified in its charter) Delaware 35‑1969‑140 (State or other jurisdiction of incorpora

October 12, 2017 CORRESP

ECYT / Endocyte, Inc. ESP

ecytCurrentFolioCORRESPAccelRequest Faegre Baker Daniels LLP 600 East 96th Street, Suite 600 Indianapolis, Indiana 46240 Phone +1 317 569 9600 Fax +1 317 569 4800 October 12, 2017 VIA EDGAR Securities and Exchange Commission 100 F Street, NE Washington, DC 20549 Re: Endocyte, Inc.

October 12, 2017 EX-4.8

Form of Subordinated Indenture

Exhibit 4.8 ENDOCYTE, INC. TO [] Trustee INDENTURE Dated as of [] Subordinated Debt Securities Endocyte, Inc. Reconciliation and tie between Trust Indenture Act of 1939 and Indenture, dated as of [] Trust Indenture Act Section Indenture Section §310(a)(1) 609 (a)(2) 609 (a)(3) Not Applicable (a)(4) Not Applicable (a)(5) 609 (b) 608, 610 §311(a) 613 (b) 613 §312(a) 701, 702(a) (b) 702(b) (c) 702(c)

October 12, 2017 EX-4.7

Form of Senior Indenture

EX-4.7 2 ex-4d7.htm EX-4.7 Exhibit 4.7 ENDOCYTE, INC. TO [ ] Trustee INDENTURE Dated as of [ ] Senior Debt Securities Endocyte, Inc. Reconciliation and tie between Trust Indenture Act of 1939 and Indenture, dated as of [ ] Trust Indenture Act Section Indenture Section §310(a) (1) 609 (a) (2) 609 (a) (3) Not Applicable (a) (4) Not Applicable (a) (5) 609 (b) 608, 610 §311(a) 613 (b) 613 §312(a) 701,

October 12, 2017 SC 13G

ECYT / Endocyte, Inc. / Cambridge Isotope Laboratories, Inc. Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. ) Endocyte, Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities) 29269A102 (CUSIP Number) September 29, 2017 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to wh

October 2, 2017 EX-99.1

Endocyte Announces Exclusive Worldwide License of Phase 3 Ready PSMA-Targeted Radioligand Therapy for Development in Prostate Cancer - Transformational Transaction Provides Endocyte with the Most Advanced Targeted Radioligand Therapy in Development f

EX-99.1 5 ex-99d1.htm EX-99.1 Exhibit 99.1 Investor Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] Media Contact: David Schull, Russo Partners, LLC., (212) 845-4271, [email protected] NEWS RELEASE Endocyte Announces Exclusive Worldwide License of Phase 3 Ready PSMA-Targeted Radioligand Therapy for Development in Prostate Cancer - Tr

October 2, 2017 EX-10.1

Development and License Agreement, dated as of September 29, 2017, between Endocyte, Inc. and ABX advanced biochemical compounds – Biomedizinische Forschungsreagenzien GmbH

Exhibit 10.1 CONFIDENTIAL TREATMENT REQUESTED Portions of this Exhibit have been redacted pursuant to a request for confidential treatment under Rule 24b-2 of the General Rules and Regulations under the Securities Exchange Act of 1934, as amended. Omitted information, marked “[*]” in this Exhibit, has been filed separately with the Securities and Exchange Commission together with such request for

October 2, 2017 EX-4.2

Registration Rights Agreement, dated as of September 29, 2017, between Endocyte, Inc. and ABX advanced biochemical compounds – Biomedizinische Forschungsreagenzien GmbH (incorporated by reference to Exhibit 4.2 to Current Report on Form 8-K filed October 2, 2017).

Exhibit 4.2 REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (this “Agreement”) is made and entered into as of September 29, 2017, by and among Endocyte, Inc., a Delaware corporation (the “Company”), and ABX advanced biochemical compounds – Biomedizinische Forschungsreagenzien GmbH, a company organized under the laws of Germany (“ABX”). WHEREAS, the Company and ABX are party to tha

October 2, 2017 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): September 29, 2017

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): September 29, 2017 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of in

October 2, 2017 EX-4.1

Form of Warrant to Purchase Shares of Common Stock, dated as of September 29, 2017 (incorporated by reference to Exhibit 4.1 to Current Report on Form 8-K filed October 2, 2017).

EX-4.1 2 ex-4d1.htm EX-4.1 Exhibit 4.1 THIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR ANY STATE OR OTHER SECURITIES LAWS AND MAY NOT BE OFFERED, SOLD, TRANSFERRED OR ASSIGNED EXCEPT (i) PURSUANT TO REGISTRATIONS THEREOF UNDER SUCH LAWS, OR (ii) IF, IN THE OPINION OF COUNSEL REASONABLY SATISFACTORY TO ENDOCYTE, INC., THE PROPOSED TRANSFER MAY BE EFFECTED IN CO

August 9, 2017 EX-10.2

Exclusive License Agreement effective March 1, 2010 between Endocyte, Inc. and Purdue Research Foundation, as amended through April 14, 2014 (incorporated by reference to Exhibit 10.2 to Quarterly Report on Form 10-Q for the quarter ended June 30, 2017 filed August 9, 2017).

Exhibit 10.2 CONFIDENTIAL TREATMENT REQUESTED Portions of this Exhibit have been redacted pursuant to a request for confidential treatment under Rule 24b-2 of the General Rules and Regulations under the Securities Exchange Act of 1934, as amended. Omitted information, marked “[*]” in this Exhibit, has been filed separately with the Securities and Exchange Commission together with such request for

August 9, 2017 EX-10.1

Amended and Restated Exclusive License Agreement dated October 21, 1998 between Endocyte, Inc. and Purdue Research Foundation, as amended through April 14, 2014 (incorporated by reference to Exhibit 10.1 to Quarterly Report on Form 10-Q for the quarter ended June 30, 2017 filed August 9, 2017).

EX-10.1 2 ecyt-20170630ex101acb552.htm EX-10.1 Exhibit 10.1 CONFIDENTIAL TREATMENT REQUESTED Portions of this Exhibit have been redacted pursuant to a request for confidential treatment under Rule 24b-2 of the General Rules and Regulations under the Securities Exchange Act of 1934, as amended. Omitted information, marked “[*]” in this Exhibit, has been filed separately with the Securities and Exch

August 9, 2017 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2017 ☐ TRANSITION REPORT PURSUANT TO S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2017 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE, INC. (Exact

August 8, 2017 EX-99.1

Endocyte Reports Second Quarter Financial Results and Provides Clinical and Pipeline Update - Plans to Initiate Clinical Development for CAR T-Cell Program in Osteosarcoma in 2018 – - Nearing Completion of Enrollment of Expansion Phase of EC1169 Tria

ecytEx991 Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Reports Second Quarter Financial Results and Provides Clinical and Pipeline Update - Plans to Initiate Clinical Development for CAR T-Cell Program in Osteosarcoma in 2018 ? - Nearing Completion of Enrollment of Expansion Phase of EC1169 Trial in Prostate Can

August 8, 2017 8-K

Endocyte 8-K (Current Report/Significant Event)

ecyt_Current_Folio_8K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

June 2, 2017 EX-99.1

Endocyte Announces Clinical Updates for EC1456 and EC1169 - Company Continuing EC1169 Program in Taxane-Exposed Patients, but Ending Clinical Development of EC1456 and of EC1169 in Taxane-Naïve Patients - - Refocusing Efforts on Chimeric Antigen Rece

EX-99.1 2 ex-99d1.htm EX-99.1 Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Announces Clinical Updates for EC1456 and EC1169 - Company Continuing EC1169 Program in Taxane-Exposed Patients, but Ending Clinical Development of EC1456 and of EC1169 in Taxane-Naïve Patients - - Refocusing Efforts on Chimeric Antigen R

June 2, 2017 8-K

Material Impairments, Costs Associated with Exit or Disposal Activities

ecytCurrentFolio8K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

May 10, 2017 EX-99.1

Endocyte Reports First Quarter Financial Results and Provides Clinical and Pipeline Update - Conference Call Today at 8:30 a.m. EDT -

ecytEx991 Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Reports First Quarter Financial Results and Provides Clinical and Pipeline Update - Conference Call Today at 8:30 a.m. EDT - West Lafayette, Ind., May 10, 2017 ? Endocyte, Inc. (NASDAQ Global Market: ECYT), a leader in developing targeted small molecule drug

May 10, 2017 8-K

Endocyte 8-K (Current Report/Significant Event)

ecytCurrentFolio8K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

May 10, 2017 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2017 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE, INC. (Exact

May 10, 2017 EX-10.3

Amendments #1 through #8 to the Master License Agreement effective July 1, 2013 between Endocyte, Inc. and Purdue Research Foundation, as amended (incorporated by reference to Exhibit 10.3 to Quarterly Report on Form 10-Q for the quarter ended March 31, 2017 filed May 10, 2017).

Exhibit 10.3 CONFIDENTIAL TREATMENT REQUESTED Portions of this Exhibit have been redacted pursuant to a request for confidential treatment under Rule 24b-2 of the General Rules and Regulations under the Securities Exchange Act of 1934, as amended. Omitted information, marked “[*]” in this Exhibit, has been filed separately with the Securities and Exchange Commission together with such request for

May 10, 2017 EX-10.1

Amendments #14 through #19 to the Amended and Restated Exclusive License Agreement dated October 21, 1998 between Endocyte, Inc. and Purdue Research Foundation, as amended (incorporated by reference to Exhibit 10.1 to Quarterly Report on Form 10-Q for the quarter ended March 31, 2017 filed May 10, 2017).

Exhibit 10.1 CONFIDENTIAL TREATMENT REQUESTED Portions of this Exhibit have been redacted pursuant to a request for confidential treatment under Rule 24b-2 of the General Rules and Regulations under the Securities Exchange Act of 1934, as amended. Omitted information, marked “[*]” in this Exhibit, has been filed separately with the Securities and Exchange Commission together with such request for

May 10, 2017 EX-10.2

Second Amendment to the Exclusive License Agreement effective March 1, 2010 between Endocyte, Inc. and Purdue Research Foundation, as amended (incorporated by reference to Exhibit 10.2 to Quarterly Report on Form 10-Q for the quarter ended March 31, 2017 filed May 10, 2017).

Exhibit 10.2 Second Amendment to the Amended and Restated License Agreement made effective on March 1, 2010 between the Purdue Research Foundation and Endocyte, Inc. (“Agreement”) This second amendment (“Amendment”), made and entered effective as of the 1st day of March, 2010 (the “Effective Date”) between Endocyte, Inc., with a place of business at 3000 Kent Avenue, Suite A1-100, West Lafayette,

May 5, 2017 8-K

Current Report

ecytCurrentFolio8K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

March 24, 2017 DEFA14A

Endocyte DEFA14A

ecytCurrent FolioDEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

March 24, 2017 DEF 14A

Endocyte DEF 14A

ecytCurrent FolioDEF14A Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

March 14, 2017 S-8 POS

Endocyte S-8 POS

ecytS8POS As filed with the Securities and Exchange Commission on March 14, 2017 Registration No.

March 14, 2017 S-8

Endocyte S-8

As filed with the Securities and Exchange Commission on March 14, 2017 Registration No.

March 13, 2017 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-K ☑ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2016 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE

March 13, 2017 EX-10.19

Separation Agreement and Release of Claims, by and between Endocyte, Inc. and Scot L. Harper, executed on October 28, 2016 (incorporated by reference to Exhibit 10.19 to the Annual Report on Form 10-K for the year ended December 31, 2016).

Exhibit 10.19 SEPARATION AGREEMENT AND RELEASE OF CLAIMS This Separation Agreement and Release of Claims (this "Agreement") is entered into by and between Endocyte, Inc. ("Endocyte"), and Scot L. Harper, Ph.D. ("Harper") (together, the "Parties") and will become effective on the date that is eight calendar days after Harper has executed and not revoked this Agreement (the "Effective Date"). Recita

March 13, 2017 EX-10.20

ENDOCYTE, INC. SCHEDULE OF TERMS FOR CHANGE IN CONTROL AND SEVERANCE AGREEMENTS WITH EXECUTIVE OFFICERS March 2017

Exhibit 10.20 ENDOCYTE, INC. SCHEDULE OF TERMS FOR CHANGE IN CONTROL AND SEVERANCE AGREEMENTS WITH EXECUTIVE OFFICERS March 2017 Termination without Cause or Resignation for Good Reason, prior to a Change in Control or after 12 months following a Change in Control Termination without Cause or Resignation for Good Reason, within 12 months following a Change in Control Name of Executive Officer Date

March 13, 2017 EX-10.16

Extension of lease dated December 1, 2016 between Endocyte, Inc. and Purdue Research Foundation (incorporated by reference to Exhibit 10.16 to Annual Report on Form 10-K for the year ended December 31, 2016 filed March 13, 2017).

Exhibit 10.16 PURDUE TECHNOLOGY CENTER 3000 Kent Avenue West Lafayette, Indiana 47906 EXTENSION OF LEASE THIS EXTENSION OF LEASE is made this first day of December, 2016 by and between PURDUE RESEARCH FOUNDATION (“Landlord”), an Indiana corporation (formed and existing under the Indiana Foundation or Holding Companies Act, Acts of 1921, ch. 246), and ENDOCYTE (“Tenant”). Landlord and Tenant have p

March 10, 2017 EX-99.2

Endocyte and Seattle Children’s Research Institute to Collaborate on Endocyte’s Small Molecule Drug Conjugate Bi-Specific Adaptor Molecules for CAR T-cell Therapies - Collaboration pairs leading SMDC technology with recognized CAR T-cell research exp

ecytEx992 Exhibit 99.2 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte and Seattle Children?s Research Institute to Collaborate on Endocyte?s Small Molecule Drug Conjugate Bi-Specific Adaptor Molecules for CAR T-cell Therapies - Collaboration pairs leading SMDC technology with recognized CAR T-cell research expert - - Plans to

March 10, 2017 EX-99.1

Endocyte Reports Fourth Quarter and Year End 2016 Financial Results and Provides Clinical and Pipeline Update - Conference Call Today at 8:30 a.m. EST -

ecytEx991 Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Reports Fourth Quarter and Year End 2016 Financial Results and Provides Clinical and Pipeline Update - Conference Call Today at 8:30 a.m. EST - West Lafayette, Ind., March 10, 2017 ? Endocyte, Inc. (NASDAQ Global Market: ECYT), a leader in developing targete

March 10, 2017 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

ecytCurrentFolio8K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

February 21, 2017 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

ecytCurrentFolio8K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

February 21, 2017 EX-99.1

Endocyte Appoints Michael T. Andriole as Chief Financial Officer

ecytEx991 Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Appoints Michael T. Andriole as Chief Financial Officer West Lafayette, Ind., Feb. 21, 2017- Endocyte, Inc. (NASDAQ Global Market: ECYT), a leader in developing targeted small molecule drug conjugates (SMDCs) and companion imaging agents for personalized the

November 9, 2016 EX-99.1

Endocyte Reports Third Quarter 2016 Financial Results - Confirmed Maximum Dose for EC1169 and Initiated Expansion Phase in Prostate Cancer Patients - - First Confirmed RECIST Partial Response Observed in EC1169 Dose Escalation Reported at European So

ecytEx991 Exhibit 99.1 Contact: Michael Schaffzin, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Reports Third Quarter 2016 Financial Results - Confirmed Maximum Dose for EC1169 and Initiated Expansion Phase in Prostate Cancer Patients - - First Confirmed RECIST Partial Response Observed in EC1169 Dose Escalation Reported at European Society for Medical

November 9, 2016 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

ecytCurrentFolio8K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

November 9, 2016 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2016 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE, INC. (E

October 20, 2016 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

ecytCurrentFolio8K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

October 11, 2016 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

ecytCurrentFolio8K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

October 11, 2016 EX-99.1

Endocyte Presents Data on Two Lead Clinical Programs at European Society for Medical Oncology (ESMO) 2016 Congress - Anti-tumor activity demonstrated in dose escalation trials for EC1456 and EC1169 –

ecytEx991 Exhibit 99.1 Contact: Michael Schaffzin, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Presents Data on Two Lead Clinical Programs at European Society for Medical Oncology (ESMO) 2016 Congress - Anti-tumor activity demonstrated in dose escalation trials for EC1456 and EC1169 ? West Lafayette, Ind., Oct. 10, 2016 - Endocyte, Inc. (NASDAQ Global

August 5, 2016 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2016 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE, INC. (Exact

August 4, 2016 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

8-K 1 ecyt-20160804x8k.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): August 4, 2016 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commis

August 4, 2016 EX-99.1

Endocyte Reports Second Quarter 2016 Financial Results - Reached Maximum Tolerated Dose in Twice Weekly Dosing Schedule with EC1456 – - Initiating EC1456 Expansion Cohort in Targeted Population of Folate Receptor-Positive Non-Small Cell Lung Cancer P

ecytEx991 Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Reports Second Quarter 2016 Financial Results - Reached Maximum Tolerated Dose in Twice Weekly Dosing Schedule with EC1456 ? - Initiating EC1456 Expansion Cohort in Targeted Population of Folate Receptor-Positive Non-Small Cell Lung Cancer Patients ? - Data

June 20, 2016 EX-99.1

Endocyte Appoints Mike Sherman as President and Chief Executive Officer

Exhibit 99.1 Contacts: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Appoints Mike Sherman as President and Chief Executive Officer West Lafayette, Ind., June 20, 2016 - Endocyte, Inc. (NASDAQ Global Market: ECYT), a leader in developing targeted small molecule drug conjugates (SMDCs) and companion imaging agents for personalized ther

June 20, 2016 EX-10.1

Separation Agreement and Release of Claims, by and between Endocyte, Inc. and P. Ron Ellis, executed on June 16, 2016 (incorporated by reference to Exhibit 10.1 to the Current Report on Form 8-K filed on June 20, 2016).

EXHIBIT 10.1 SEPARATION AGREEMENT AND RELEASE OF CLAIMS This Separation Agreement and Release of Claims (this "Agreement") is entered into by and between Endocyte, Inc. ("Endocyte"), and P. Ron Ellis ("Ellis") (together, the "Parties") and will become effective on the date that is eight days after Ellis has executed and not revoked this Agreement (the ?Effective Date?). Recitals A. Ellis has tende

June 20, 2016 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) June 16, 2016 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (IRS Employer of incorporati

May 9, 2016 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) May 5, 2016 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (IRS Employer of incorporation

May 6, 2016 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q þ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2016 OR ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE, INC. (Exact

May 4, 2016 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 4, 2016 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of incorpora

May 4, 2016 EX-99.1

Endocyte Reports First Quarter 2016 Financial Results - Data from Phase 1 Dose Escalation Studies of EC1456 and EC1169 to be Presented at ASCO - - Expansion Phase of Trials in Targeted Patients Expected to Yield Efficacy Data in 2016 - - Promising Pr

Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Reports First Quarter 2016 Financial Results - Data from Phase 1 Dose Escalation Studies of EC1456 and EC1169 to be Presented at ASCO - - Expansion Phase of Trials in Targeted Patients Expected to Yield Efficacy Data in 2016 - - Promising Preclinical Data Demonstrates

April 20, 2016 8-K

Regulation FD Disclosure

8-K 1 v4375228k.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 31, 2016 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commissi

April 19, 2016 EX-99.1

Endocyte Announces Promising Preclinical Data for Application of SMDC Technology in CAR T Cell Therapy in Late-Breaking Abstract at American Association for Cancer Research (AACR) Annual Meeting 2016

Exhibit 99.1 Contacts: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Announces Promising Preclinical Data for Application of SMDC Technology in CAR T Cell Therapy in Late-Breaking Abstract at American Association for Cancer Research (AACR) Annual Meeting 2016 ? Poster demonstrates novel approach to a universal T cell overcoming key ch

April 19, 2016 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) April 19, 2016 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (IRS Employer of incorporat

March 23, 2016 DEFA14A

Endocyte DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Defin

March 23, 2016 DEF 14A

Endocyte DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

March 9, 2016 S-8 POS

Endocyte POST-EFFECTIVE AMENDMENT NO. 3

As filed with the Securities and Exchange Commission on March 9, 2016 Registration No.

March 9, 2016 S-8

Endocyte FORM S-8

As filed with the Securities and Exchange Commission on March 9, 2016 Registration No.

March 8, 2016 EX-4.3

Reissued Warrant to Purchase Shares of Common Stock reissued by Endocyte, Inc. to Healthcare Equity Holdings, LLC on November 30, 2015 (incorporated by reference to Exhibit 4.3 to Annual Report on Form 10-K for the year ended December 31, 2015 filed March 8, 2016).

EX-4.3 2 v432293ex4-3.htm EXHIBIT 4.3 Exhibit 4.3 NEITHER THIS WARRANT NOR THE SECURITIES ISSUABLE UPON EXERCISE OF THIS WARRANT HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED. SUBJECT TO SECTION 6 BELOW, NO SALE OR DISPOSITION MAY BE EFFECTED EXCEPT IN COMPLIANCE WITH RULE 144 UNDER SAID ACT OR WITHOUT AN EFFECTIVE REGISTRATION STATEMENT RELATED THERETO OR AN OPINION OF COUNSEL

March 8, 2016 EX-10.18

Lease Agreement dated December 8, 2015 between Endocyte, Inc. and Purdue Research Foundation (incorporated by reference to Exhibit 10.18 to Annual Report on Form 10-K for the year ended December 31, 2015 filed March 8, 2016).

Exhibit 10.18 PURDUE TECHNOLOGY CENTER 3000 KENT AVENUE WEST LAFAYETTE, INDIANA 47906 LEASE AGREEMENT THIS LEASE AGREEMENT (the “Lease”) is made and entered into as of this 8th day of December, 2015, by and between PURDUE RESEARCH FOUNDATION (“Landlord”), an Indiana corporation (formed and existing under the Indiana Foundation or Holding Companies Act, Acts of 1921, ch. 246), and ENDOCYTE (“Tenant

March 8, 2016 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-K ENDOCYTE, INC. ENDOCYTE, INC. ANNUAL REPORT ON FORM 10-K FOR THE YEAR ENDED DECEMBER 31, 2015 INDEX PART I PART II ENDOCYTE, INC. INDEX TO FINANCIAL STATEMENTS REPORT O

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-K þ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2015 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE, INC. (Exact name

March 2, 2016 EX-99.1

Endocyte Reports Fourth Quarter and Year End 2015 Financial Results and Provides Clinical and Pipeline Update - EC1456 and EC1169 Advance in Phase 1 Dose Escalation Studies - - Expansion Phase of Trials in Targeted Patients Expected to Yield Efficacy

EX-99.1 2 v433241ex99-1.htm EXHIBIT 99.1 Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Reports Fourth Quarter and Year End 2015 Financial Results and Provides Clinical and Pipeline Update - EC1456 and EC1169 Advance in Phase 1 Dose Escalation Studies - - Expansion Phase of Trials in Targeted Patients Expected to

March 2, 2016 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 2, 2016 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of incorpo

January 5, 2016 8-K

Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): January 5, 2016 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of incor

November 4, 2015 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q þ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2015 OR ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE, INC. (E

November 3, 2015 EX-99.1

Endocyte Reports Third Quarter 2015 Financial Results and Provides Update on Clinical Progress - Dose Escalation for EC1456 and EC1169 Advance in Phase 1 Studies - - Conference Call Today at 4:30 p.m. EDT -

EX-99.1 2 v423614ex99-1.htm EX-99.1 Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Reports Third Quarter 2015 Financial Results and Provides Update on Clinical Progress - Dose Escalation for EC1456 and EC1169 Advance in Phase 1 Studies - - Conference Call Today at 4:30 p.m. EDT - West Lafayette, Ind., Nov. 3, 2015

November 3, 2015 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

8-K 1 v4236148k.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): November 3, 2015 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission

September 10, 2015 EX-99.1

Endocyte Announces Final Overall Survival Results from Phase 2b TARGET Trial in Non-Small Cell Lung Cancer Patients

EX-99.1 2 v420028ex99-1.htm EXHIBIT 99.1 Exhibit 99.1 Contacts: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Announces Final Overall Survival Results from Phase 2b TARGET Trial in Non-Small Cell Lung Cancer Patients – Supports Folate Receptor (FR) as a Valid Target in Non-Small Cell Lung Cancer (NSCLC) – WEST LAFAYETTE, Ind., Sept.7,

September 10, 2015 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

8-K 1 v4200288k.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) September 7, 2015 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission

August 5, 2015 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q þ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2015 OR ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE, INC. (Exact

August 4, 2015 EX-24

Limited Power of Attorney Securities Law Compliance

Exhibit 24 Limited Power of Attorney Securities Law Compliance The undersigned, as an officer or director of Endocyte, Inc.

August 4, 2015 EX-99.1

Endocyte Reports Second Quarter 2015 Financial Results and Provides Update on Clinical Progress - Dose Escalation for EC1456 and EC1169 Advance in Phase 1 Studies - - Final Overall Survival Analysis from TARGET Trial of EC145 in NSCLC to be presented

Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Endocyte Reports Second Quarter 2015 Financial Results and Provides Update on Clinical Progress - Dose Escalation for EC1456 and EC1169 Advance in Phase 1 Studies - - Final Overall Survival Analysis from TARGET Trial of EC145 in NSCLC to be presented at the World Conference on

August 4, 2015 8-K

Endocyte 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): August 4, 2015 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of incorp

May 28, 2015 SC 13G/A

ECYT / Endocyte, Inc. / Pension Fund of the Christian Church (Disciples of Christ) Inc - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1) Endocyte, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title or Class of Securities) 29269A102 (CUSIP Number) December 31, 2014 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pu

May 18, 2015 8-K

Current Report

8-K 1 v4110178k.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) May 14, 2015 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (IRS

May 18, 2015 EX-10.1

Form of Endocyte, Inc. Change in Control and Severance Agreement (incorporated by reference to Exhibit 10.1 to the Current Report on Form 8-K filed on May 18, 2015)

Exhibit 10.1 ENDOCYTE, INC. CHANGE IN CONTROL AND SEVERANCE AGREEMENT This Change in Control and Severance Agreement (the ?Agreement?) is made and entered into by and between (?Employee?) and Endocyte, Inc., a Delaware corporation (the ?Company?), effective as of , 2015 (the ?Effective Date?). RECITALS 1. It is possible that the Company could terminate Employee?s employment with the Company and it

May 8, 2015 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2015 OR ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE, INC. (Exact

May 7, 2015 8-K

Endocyte 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 7, 2015 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of incorpora

May 7, 2015 EX-99.1

Endocyte Reports First Quarter 2015 Financial Results and Provides Update on Clinical Progress - Dose Escalation for EC1456 and EC1169 Move to Fifth Dosing Cohorts Evaluating Two Schedules for Each Agent – - Conference Call Today at 4:30 p.m. EDT –

Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE: Endocyte Reports First Quarter 2015 Financial Results and Provides Update on Clinical Progress - Dose Escalation for EC1456 and EC1169 Move to Fifth Dosing Cohorts Evaluating Two Schedules for Each Agent ? - Conference Call Today at 4:30 p.m. EDT ? West Lafayette, Ind., May 7

April 2, 2015 DEFA14A

Endocyte DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Defin

April 2, 2015 DEF 14A

Endocyte DEFINITIVE_14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

March 16, 2015 S-8 POS

Endocyte S-8 POS

S-8 POS 1 v404470s8pos.htm S-8 POS As filed with the Securities and Exchange Commission on March 16, 2015 Registration No. 333-172121 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Post-effective amendment no. 2 to Form S-8 registration statement UNDER THE SECURITIES ACT OF 1933 ENDOCYTE, INC. (Exact name of registrant as specified in its charter) Delaware 35-1969-140 (Sta

March 16, 2015 S-8

Endocyte S-8

As filed with the Securities and Exchange Commission on March 16, 2015 Registration No.

March 13, 2015 EX-10.25

PURDUE TECHNOLOGY CENTER 3000 kent avenue west lafayette, indiana 47906 EXTENSION OF LEASE EXHIBIT A LEASED PREMISES

Exhibit 10.25 PURDUE TECHNOLOGY CENTER 3000 kent avenue west lafayette, indiana 47906 EXTENSION OF LEASE THIS EXTENSION OF LEASE is made this 9th day of December, 2014 by and between PURDUE RESEARCH FOUNDATION (“Landlord”), an Indiana corporation (formed and existing under the Indiana Foundation or Holding Companies Act, Acts of 1921, ch. 246), and ENDOCYTE (“Tenant”). Landlord and Tenant have pre

March 13, 2015 EX-10.14

Master License Agreement effective July 1, 2013 between Endocyte, Inc. and Purdue Research Foundation (incorporated by reference to Exhibit 10.14 to Annual Report on Form 10-K for the year ended December 31, 2014).

Exhibit 10.14 CONFIDENTIAL TREATMENT REQUESTED [*] = Certain confidential information contained in this document, marked with brackets, has been omitted and filed separately with the Securities and Exchange Commission pursuant to a request for confidential treatment pursuant to, as applicable, Rule 24b-2 of the Securities Exchange Act of 1934, as amended, and Rule 406 of the Securities Act of 1933

March 13, 2015 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-K ENDOCYTE, INC. ENDOCYTE, INC. ANNUAL REPORT ON FORM 10-K FOR THE YEAR ENDED DECEMBER 31, 2014 INDEX PART I PART II ENDOCYTE, INC. INDEX TO FINANCIAL STATEMENTS REPORT O

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-K þ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2014 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE, INC. (Exact name

March 2, 2015 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 2, 2015 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of incorpo

March 2, 2015 EX-99.1

Endocyte Reports Fourth Quarter and Year End 2014 Financial Results and Provides Clinical Update - Dose Escalation Continues for EC1456 and EC1169 as Endocyte Outlines Plans for Expansion of the Trials in Targeted Patients Once Maximum Doses are Dete

EX-99.1 2 v403268ex99-1.htm EXHIBIT 99.1 Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE: Endocyte Reports Fourth Quarter and Year End 2014 Financial Results and Provides Clinical Update - Dose Escalation Continues for EC1456 and EC1169 as Endocyte Outlines Plans for Expansion of the Trials in Targeted Patients Once Maximum

February 12, 2015 SC 13G/A

ECYT / Endocyte, Inc. / BB BIOTECH AG - SC 13G/A Passive Investment

SC 13G/A United States SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3; Exit Filing)* ENDOCYTE, INC. (Name of Issuer) Common Stock (Title of Class of Securities) 29269A102 (CUSIP Number) December 31, 2014 (Date of Event Which Requires Filing This Statement) Check the appropriate box to designate the rule pursuant to

November 7, 2014 EX-10.1

SEPARATION AGREEMENT AND RELEASE OF CLAIMS

EX-10.1 2 v392677ex10-1.htm EXHIBIT 10.1 Exhibit 10.1 SEPARATION AGREEMENT AND RELEASE OF CLAIMS This Separation Agreement and Release of Claims ("Agreement") is entered into by and between Endocyte, Inc. ("Endocyte"), and David D. Meek ("Meek") (collectively, the "Parties"). Recitals A. Endocyte and Meek are parties to a Change in Control and Severance Agreement ("Severance Agreement"), a copy of

November 7, 2014 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q

10-Q 1 v39267710q.htm FORM 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q þ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2014 OR ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file nu

November 5, 2014 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): November 5, 2014 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of inco

November 5, 2014 EX-99.1

Endocyte Reports Third Quarter Financial Results and Provides Clinical Update

Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE: Endocyte Reports Third Quarter Financial Results and Provides Clinical Update - Folate-targeted EC1456 with Potent Tubulysin Payload Now at Higher Phase 1 Dose Level than Vintafolide – - Conference Call Today at 4:30 p.m. EST – West Lafayette, Ind., Nov. 5, 2014 – Endocyte, I

October 1, 2014 EX-99.1

Phase 2b TARGET Trial Results Show Improved Survival in Adenocarcinoma Non-Small Cell Lung Cancer Patients Treated with Endocyte’s Vintafolide

Exhibit 99.1 Contacts: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE Phase 2b TARGET Trial Results Show Improved Survival in Adenocarcinoma Non-Small Cell Lung Cancer Patients Treated with Endocyte’s Vintafolide - Data Presented Today as Late-Breaker at European Society for Medical Oncology (ESMO) 2014 Congress in Madrid - - Interim Update of

October 1, 2014 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) September 27, 2014 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (IRS Employer of incorp

August 8, 2014 EX-10.1

FOURTH AMENDMENT OF LEASE AGREEMENT

Exhibit 10.1 FOURTH AMENDMENT OF LEASE AGREEMENT THIS AGREEMENT is executed in duplicate and effective this 1st day of April, 2014, by and between PURDUE RESEARCH FOUNDATION , an Indiana corporation (formed and existing under the Indiana Foundation or Holding Companies Act, Acts of 1921, ch. 25), (“PRF”), and ENDOCYTE (“COMPANY”). In consideration of their mutual promises contained in this Amendme

August 8, 2014 EX-10.2

LICENSE AGREEMENT ENDOCYTE, INC PURDUE RESEARCH FOUNDATION OCTOBER 21, 1998

Exhibit 10.2 CONFIDENTIAL TREATMENT REQUESTED [*] = Certain confidential information contained in this document, marked with brackets, has been omitted and filed separately with the Securities and Exchange Commission pursuant to a request for confidential treatment pursuant to, as applicable, Rule 24b-2 of the Securities Exchange Act of 1934, as amended, and Rule 406 of the Securities Act of 1933,

August 8, 2014 EX-10.3

EXCLUSIVE LICENSE AGREEMENT

EX-10.3 4 v384793ex10-3.htm EXHIBIT 10.3 Exhibit 10.3 CONFIDENTIAL TREATMENT REQUESTED [*] = Certain confidential information contained in this document, marked with brackets, has been omitted and filed separately with the Securities and Exchange Commission pursuant to a request for confidential treatment pursuant to, as applicable, Rule 24b-2 of the Securities Exchange Act of 1934, as amended, an

August 8, 2014 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q R QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2014 OR ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE, INC. (Exact

July 29, 2014 EX-99.1

Endocyte Reports Second Quarter Financial Results and Provides Clinical Update - EC1456 Targeting Potent Tubulysin Payload to Advance in Phase 1 to Dose Similar to Vintafolide– - Conference Call Today at 4:30 p.m. EDT –

EX-99.1 2 v385058ex99-1.htm EXHIBIT 99.1 Exhibit 99.1 Contact: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] NEWS RELEASE: Endocyte Reports Second Quarter Financial Results and Provides Clinical Update - EC1456 Targeting Potent Tubulysin Payload to Advance in Phase 1 to Dose Similar to Vintafolide– - Conference Call Today at 4:30 p.m. EDT – West Lafayette,

July 29, 2014 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

8-K 1 v3850588k.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): July 29, 2014 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.

June 23, 2014 8-K

Regulation FD Disclosure, Termination of a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): June 17, 2014 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of incorpo

June 23, 2014 EX-99.1

Endocyte Regains Worldwide Rights to Vintafolide

Exhibit 99.1 Contacts: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] Martina Schwarzkopf, Ph.D., Russo Partners, (212) 845-4292, [email protected] Tony Russo, Ph.D., Russo Partners, (212) 845-4251, [email protected] FOR IMMEDIATE RELEASE: Endocyte Regains Worldwide Rights to Vintafolide West Lafayette, Ind., June 17, 20

June 19, 2014 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): June 16, 2014 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of incorpo

June 2, 2014 8-K

- 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): June 2, 2014 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of incorpor

May 21, 2014 8-K

Regulation FD Disclosure, Financial Statements and Exhibits - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 19, 2014 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of incorpor

May 21, 2014 EX-99.1

Merck and Endocyte Announce Withdrawal of Conditional Marketing Authorization Applications for Vintafolide and Companion Imaging Components, Etarfolatide and Intravenous (IV) Folic Acid in Europe

Exhibit 99.1 Contacts: Merck: Media: Ian McConnell +1 908-423-3046 Claire Mulhearn +1 908-423-7425 Investors: Carol Ferguson +1 908-423-4465 Justin Holko +1 908-423-5088 Endocyte: Media: Martina Schwarzkopf, Ph.D., Russo Partners +1 212-845-4292 Tony Russo, Ph.D., Russo Partners, +1 212-845-4251 Investors: Stephanie Ascher, Stern Investor Relations, Inc., +1 212-362-1200 FOR IMMEDIATE RELEASE: Mer

May 16, 2014 8-K

- 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) May 15, 2014 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (IRS Employer of incorporatio

May 12, 2014 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington , D.C. 20549 Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington , D.C. 20549 Form 10-Q R QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2014 OR ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE, INC. (Exac

May 12, 2014 EX-10.1

THIRD AMENDMENT OF LEASE AGREEMENT

EXHIBIT 10.1 THIRD AMENDMENT OF LEASE AGREEMENT THIS AGREEMENT is executed in duplicate and effective this 31st day of January, 2014, by and between PURDUE RESEARCH FOUNDATION , an Indiana corporation (formed and existing under the Indiana Foundation or Holding Companies Act, Acts of 1921, ch. 25), (“PRF”), and ENDOCYTE (“COMPANY”). In consideration of their mutual promises contained in this Amend

May 2, 2014 EX-99.1

Endocyte Reports First Quarter Financial Results and Provides Clinical Update - Independent DSMB Recommends to Stop Phase 3 PROCEED Trial for Futility Following Interim Analysis - - Endocyte Initiates Phase 1 Trial of PSMA-Targeted Tubulysin SMDC (EC

EX-99.1 2 v376995ex99-1.htm EXHIBIT 99.1 Exhibit 99.1 Contacts: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] Martina Schwarzkopf, Ph.D., Russo Partners, (212) 845-4292, [email protected] Tony Russo, Ph.D., Russo Partners, (212) 845-4251, [email protected] FOR IMMEDIATE RELEASE: Endocyte Reports First Quarter Financial

May 2, 2014 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 2, 2014 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of incorpora

May 2, 2014 EX-99.2

Merck and Endocyte Announce Independent DSMB Recommends Vintafolide PROCEED Phase 3 Trial Be Stopped for Futility Following Interim Analysis

Exhibit 99.2 Contacts: Merck: Media: Ian McConnell +1 908-423-3046 [email protected] Claire Mulhearn +1 908-423-7425 [email protected] Investors: Carol Ferguson +1 908-423-4465 [email protected] Justin Holko +1 908-423-5088 [email protected] Endocyte: Media: Martina Schwarzkopf, Ph.D., Russo Partners +1 212- 845-4292 [email protected] Tony Russo, Ph

March 31, 2014 EX-1.1

4,500,000 Shares ENDOCYTE, INC. Common Stock UNDERWRITING AGREEMENT

Exhibit 1.1 EXECUTION VERSION 4,500,000 Shares ENDOCYTE, INC. Common Stock UNDERWRITING AGREEMENT March 27, 2014 Credit Suisse Securities (USA) LLC, Citigroup Global Markets Inc. As Representatives of the Several Underwriters, c/o Credit Suisse Securities (USA) LLC, Eleven Madison Avenue, New York, N.Y. 10010-3629 c/o Citigroup Global Markets Inc., 388 Greenwich Street, New York, N.Y. 10013 Dear S

March 31, 2014 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

8-K 1 v3731858k.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) March 27, 2014 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commissio

March 28, 2014 424B5

Calculation of Registration Fee Title of securities to be registered Amount to be registered (1) Proposed maximum offering price per share Proposed maximum aggregate offering price Amount of registration fee (1) Common Stock, $.001 par value per shar

424B5 1 d698741d424b5.htm 424B5 Table of Contents Filed pursuant to Rule 424(b)(5) File No. 333-194791 Calculation of Registration Fee Title of securities to be registered Amount to be registered (1) Proposed maximum offering price per share Proposed maximum aggregate offering price Amount of registration fee (1) Common Stock, $.001 par value per share 5,175,000 shares $21.00 $108,675,000 $13,997.

March 25, 2014 EX-99.1

Merck and Endocyte Announce European CHMP Positive Opinions for VYNFINIT® (vintafolide) and Companion Imaging Agents FOLCEPRI® (etarfolatide) and NEOCEPRI® (Intravenous (IV) folic acid) in Patients with Platinum-Resistant Ovarian Cancer

Exhibit 99.1 Endocyte Contacts: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] Martina Schwarzkopf, Ph.D., Russo Partners, (212) 845-4292, [email protected] Tony Russo, Ph.D., Russo Partners, (212) 845-4251, [email protected] Merck Contacts: Media: Ian McConnell, (908) 423-3046 Claire Mulhearn, (908)423-7425 Investors: C

March 25, 2014 DEF 14A

- DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant þ Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) þ Defin

March 25, 2014 POS AM

- POS AM

POS AM As filed with the Securities and Exchange Commission on March 25, 2014 Registration No.

March 25, 2014 EX-12.1

STATEMENT REGARDING COMPUTATION OF RATIO/DEFICIENCY OF EARNINGS TO FIXED (dollars in thousands) Fiscal Year Ended December 31 2009 2010 2011 2012 2013 Fixed charges: Interest expense on indebtedness $ 1,226 $ 904 $ 1,342 $ 555 $ 2 Noncash interest ex

EX-12.1 Exhibit 12.1 STATEMENT REGARDING COMPUTATION OF RATIO/DEFICIENCY OF EARNINGS TO FIXED CHARGES (dollars in thousands) Fiscal Year Ended December 31 2009 2010 2011 2012 2013 Fixed charges: Interest expense on indebtedness $ 1,226 $ 904 $ 1,342 $ 555 $ 2 Noncash interest expense and other 210 161 646 74 — Interest expense on portion of rent expense representative of interest 51 53 61 74 — Tot

March 25, 2014 S-3ASR

- S-3ASR

S-3ASR 1 d700701ds3asr.htm S-3ASR Table of Contents As filed with the Securities and Exchange Commission on March 25, 2014 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-3 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 ENDOCYTE, INC. (Exact name of registrant as specified in its charter) Delaware 35-1969-140 (State or other jurisdictio

March 25, 2014 EX-99.2

Endocyte Announces Phase 2b TARGET Trial Results Evaluating Vintafolide/Docetaxel Combination in Non-Small Cell Lung Cancer (NSCLC) Met the Primary Endpoint of Improved Progression Free Survival - Conference Call/Webcast at 9 a.m. EDT Today -

Exhibit 99.2 Endocyte Contacts: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] Martina Schwarzkopf, Ph.D., Russo Partners, (212) 845-4292, [email protected] Tony Russo, Ph.D., Russo Partners, (212) 845-4251, [email protected] NEWS RELEASE Endocyte Announces Phase 2b TARGET Trial Results Evaluating Vintafolide/Docetaxel C

March 25, 2014 424B5

Subject to Completion Preliminary Prospectus Supplement dated March 25, 2014

Table of Contents The information in this prospectus supplement and accompanying prospectus is not complete and may be changed.

March 25, 2014 8-K

- FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) March 21, 2014 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (IRS Employer of incorporat

March 25, 2014 DEFA14A

- DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Defin

March 6, 2014 S-8

- S-8

As filed with the Securities and Exchange Commission on March 6, 2014 Registration No.

March 5, 2014 EX-10.21

PURDUE TECHNOLOGY CENTER 3000 kent avenue west lafayette, indiana 47906 EXTENSION OF LEASE

EX-10.21 2 v369266ex10-21.htm EXHIBIT 10.21 Exhibit 10.21 PURDUE TECHNOLOGY CENTER 3000 kent avenue west lafayette, indiana 47906 EXTENSION OF LEASE THIS EXTENSION OF LEASE is made this 20th day of November, 2013 by and between PURDUE RESEARCH FOUNDATION (“Landlord”), an Indiana corporation (formed and existing under the Indiana Foundation or Holding Companies Act, Acts of 1921, ch. 246), and ENDO

March 5, 2014 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-K ENDOCYTE, INC. ENDOCYTE, INC ANNUAL REPORT ON FORM 10-K FOR THE YEAR ENDED DECEMBER 31, 2013 INDEX PART I Kaplan-Meier curve for PFS in PRECEDENT Cellular Uptake of Fol

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-K þ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2013 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE, INC. (Exact name

February 24, 2014 EX-99.1

Endocyte Reports Fourth Quarter and Year End 2013 Financial Results and Provides Business Update

Exhibit 99.1 Contacts: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] Martina Schwarzkopf, Ph.D., Russo Partners, (212) 845-4292, [email protected] Tony Russo, Ph.D., Russo Partners, (212) 845-4251, [email protected] FOR IMMEDIATE RELEASE: Endocyte Reports Fourth Quarter and Year End 2013 Financial Results and Provides B

February 24, 2014 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

8-K 1 v3694958k.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): February 24, 2014 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commi

February 12, 2014 SC 13G/A

ECYT / Endocyte, Inc. / BB BIOTECH AG - SC 13G/A Passive Investment

SC 13G/A United States SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* ENDOCYTE, INC. (Name of Issuer) Common Stock (Title of Class of Securities) 29269A102 (CUSIP Number) December 31, 2013 (Date of Event Which Requires Filing This Statement) Check the appropriate box to designate the rule pursuant to which this Sc

February 10, 2014 EX-10.1

Form of Endocyte, Inc. 2010 Equity Incentive Plan Time-Based Restricted Stock Unit Award Agreement (incorporated by reference to Exhibit 10.1 to Current Report on Form 8-K filed February 10, 2014).

EXHIBIT 10.1 ENDOCYTE, INC. 2010 EQUITY INCENTIVE PLAN TIME-BASED RESTRICTED STOCK UNIT AWARD AGREEMENT This Award Agreement (“Award Agreement”), dated as of , 20, is by and between Endocyte, Inc., a Delaware corporation (the “Company”), and (“Participant”). Unless otherwise defined herein, the terms defined in the Endocyte, Inc. 2010 Equity Incentive Plan (the “Plan”), shall have the same defined

February 10, 2014 8-K

- FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): February 6, 2014 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of inco

December 23, 2013 424B5

Up to $60,000,000 of Shares of Common Stock

424b5 Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-187334 PROSPECTUS SUPPLEMENT (to Prospectus dated April 23, 2013) Up to $60,000,000 of Shares of Common Stock We have entered into a sales agreement with Cowen and Company, LLC, or Cowen, relating to shares of our common stock offered by this prospectus supplement and the accompanying prospectus. In accordance with the t

December 23, 2013 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) December 20, 2013 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (IRS Employer of incorpo

December 23, 2013 EX-1.1

Endocyte, Inc. COMMON STOCK SALES AGREEMENT

Exhibit 1.1 EXECUTION VERSION Endocyte, Inc. $60,000,000 COMMON STOCK SALES AGREEMENT December 20, 2013 Cowen and Company, LLC 599 Lexington Avenue New York, NY 10022 Ladies and Gentlemen: Endocyte, Inc. (the “Company”), confirms its agreement (this “Agreement”) with Cowen and Company, LLC (“Cowen”), as follows: 1. Issuance and Sale of Shares. The Company agrees that, from time to time during the

November 8, 2013 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q R QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2013 OR ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-35050 ENDOCYTE, INC. (E

November 8, 2013 EX-10.1

SECOND AMENDMENT OF LEASE AGREEMENT

EX-10.1 2 v358770ex10-1.htm EXHIBIT 10.1 Exhibit 10.1 SECOND AMENDMENT OF LEASE AGREEMENT THIS AGREEMENT is executed in duplicate and effective this 7th day of July, 2013, by and between PURDUE RESEARCH FOUNDATION , an Indiana corporation (formed and existing under the Indiana Foundation or Holding Companies Act, Acts of 1921, ch. 25), (“PRF”), and ENDOCYTE (“COMPANY”). In consideration of their m

November 7, 2013 8-K

Current Report

8-K 1 v3597448k.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): November 7, 2013 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission

November 7, 2013 EX-99.1

Colin Goddard, Ph.D., Joins the Endocyte Board of Directors

Exhibit 99.1 Contacts: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200 Martina Schwarzkopf, Ph.D., Russo Partners, (212) 845-4292 Tony Russo, Ph. D., Russo Partners, (212) 845 4251 NEWS RELEASE Colin Goddard, Ph.D., Joins the Endocyte Board of Directors West Lafayette, Ind., Nov. 7, 2013 – Endocyte, Inc. (NASDAQ Global Market: ECYT), a biopharmaceutical company and leader in devel

November 5, 2013 EX-99.1

Endocyte Reports Third Quarter 2013 Financial Results and Provides Business Update

Exhibit 99.1 Contacts: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] Martina Schwarzkopf, Ph.D., Russo Partners, (212) 845-4292, [email protected] Tony Russo, Ph.D., Russo Partners, (212) 845-4251, [email protected] NEWS RELEASE Endocyte Reports Third Quarter 2013 Financial Results and Provides Business Update - Confere

November 5, 2013 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): November 5, 2013 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of inco

October 11, 2013 EX-99.1

Endocyte Announces DSMB Recommendation for Continuation of Vintafolide/Docetaxel Combination and Docetaxel Monotherapy Arms of the Phase 2b TARGET Trial in Non-Small Cell Lung Cancer - DSMB Recommendations Following Interim Futility Analysis - - DSMB

Exhibit 99.1 Contacts: Stephanie Ascher, Stern Investor Relations, Inc., (212) 362-1200, [email protected] Martina Schwarzkopf, Ph.D., Russo Partners, (212) 845-4292, [email protected] Tony Russo, Ph.D., Russo Partners, (212) 845-4251, [email protected] NEWS RELEASE Endocyte Announces DSMB Recommendation for Continuation of Vintafolide/Docetaxel Combination

October 11, 2013 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) October 11, 2013 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (IRS Employer of incorpor

September 26, 2013 8-K

Regulation FD Disclosure - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): September 25, 2013 Endocyte, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35050 35-1969-140 (State or other jurisdiction (Commission (I.R.S. Employer of in

August 9, 2013 EX-10.1

FIRST AMENDMENT OF LEASE AGREEMENT

EX-10.1 3 v351492ex10-1.htm EXHIBIT 10.1 EXHIBIT 10.1 FIRST AMENDMENT OF LEASE AGREEMENT THIS AGREEMENT is executed in duplicate this 17th day of May, 2013, by and between PURDUE RESEARCH FOUNDATION, an Indiana corporation, of Tippecanoe County, Indiana, (“Lessor”), and ENDOCYTE (“Tenant”). In consideration of their mutual promises contained in this Amendment, the parties agree as follows: WHEREAS

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