INIS / International Isotopes Inc. - Pengajuan SECLaporan Tahunan, Pernyataan Proksi

International Isotopes Inc.
US ˙ OTCPK

Mga Batayang Estadistika
CIK 1038277
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to International Isotopes Inc.
SEC Filings (Chronological Order)
Halaman ini menyediakan daftar lengkap dan kronologis dari Pengajuan SEC, tidak termasuk pengajuan kepemilikan yang kami sediakan di tempat lain.
August 13, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 00

July 16, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 10, 2025 INTERNATIONAL ISOTO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 10, 2025 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commission Fi

May 27, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defin

May 27, 2025 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☒ Defin

May 16, 2025 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defin

May 15, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0

April 30, 2025 10-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K/A (Amendment No. 1)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K/A (Amendment No. 1) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For The Transition Period From To Commission file number: 000-22923 INTER

March 4, 2025 EX-19.1

International Isotopes Inc. Insider Trading Policy

Exhibit 19.1 INTERNATIONAL ISOTOPES INC. INSIDER TRADING POLICY I. INTRODUCTION "Insider trading" refers generally to buying or selling a security, in breach of a fiduciary duty or other relationship of trust and confidence, while in possession of material, nonpublic information about the security. Insider trading violations may also include "tipping" such information, securities trading by the pe

March 4, 2025 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 ☐ TRANSITION REPORT PURSUANT TO SECTI

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 000-22923 INTERNA

March 4, 2025 EX-21.1

Subsidiary list.

Exhibit 21.1 SUBSIDIARY LIST Name of Subsidiary State Incorporation International Isotopes Idaho Inc. Idaho International Isotopes Fluorine Products Inc. Idaho International Isotopes Transportation Services Inc. Idaho RadQual, LLC Idaho TI Services, LLC Ohio RadVent, LLC Idaho Radnostix, LLC Idaho

November 12, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file numbe

October 2, 2024 EX-3.1

Certificate of Amendment to Statement of Designation of the Series C Convertible Redeemable Preferred Stock International Isotopes Inc., dated September 26, 2024.

Exhibit 3.1 CERTIFICATE OF AMENDMENT TO STATEMENT OF DESIGNATION OF THE SERIES C CONVERTIBLE REDEEMABLE PREFERRED STOCK OF INTERNATIONAL ISOTOPES INC. (Pursuant to Sections 21.155, 21.156, and 21.364 of the Texas Business Organizations Code) INTERNATIONAL ISOTOPES INC. (File No. 137545000), a corporation organized under the Texas Business Corporation Act and existing under the Texas Business Organ

October 2, 2024 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Material Modification to Rights of Security Holders

-12-31 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 26, 2024 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (C

August 14, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-

July 16, 2024 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 10, 2024 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commission Fi

May 21, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defin

May 15, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0

April 29, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14

April 29, 2024 SC 13G/A

INIS / International Isotopes Inc. / Kennerman Associates, Inc. - SC 13G/A Passive Investment

SC 13G/A 1 tm2412913d1sc13ga.htm SC 13G/A     UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549   SCHEDULE 13G   Under the Securities Exchange Act of 1934 (Amendment No.  16)*   INTERNATIONAL ISOTOPES INC.   (Name of Issuer)   Common Stock, $.01 par value   (Title of Class of Securities)   45972C102   (CUSIP Number)   December 31, 2023   (Date of Event which Requires Filing o

March 29, 2024 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 ☐ TRANSITION REPORT PURSUANT TO SECTI

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 000-22923 INTERNA

March 29, 2024 EX-21.1

Subsidiary list.

Exhibit 21.1 SUBSIDIARY LIST Name of Subsidiary State Incorporation International Isotopes Idaho Inc. Idaho International Isotopes Fluorine Products Inc. Idaho International Isotopes Transportation Services Inc. Idaho RadQual, LLC Idaho TI Services, LLC Ohio

February 8, 2024 EX-99.1

-End-

Exhibit 99.1 FOR IMMEDIATE RELEASE: February 8, 2024 INTERNATIONAL ISOTOPES TO DIVEST DEPLETED URANIUM DECONVERSION ASSETS TO AMERICAN FUEL RESOURCES FOR $12,500,000 CASH. IDAHO FALLS, IDAHO, February 8,2024. International Isotopes Inc. (OTCQB: INIS) (“International Isotopes,” “INIS” or the “Company”) is pleased to announce that it has entered into a definitive agreement to sell all of its assets

February 8, 2024 8-K

Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 8, 2024 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commission

February 8, 2024 EX-10.1

Asset Purchased Agreement, dated February 8, 2024, among International Isotopes Inc., International Isotopes Fluorine Products, Inc. and American Fuel Resources, LLC.

Exhibit 10.1 CERTAIN CONFIDENTIAL INFORMATION, IDENTIFIED BY BRACKETED ASTERISKS “[***]”, HAS BEEN OMITTED FROM THIS EXHIBIT BECAUSE IT IS BOTH (I) NOT MATERIAL AND (II) WOULD BE COMPETITIVELY HARMFUL IF PUBLICLY DISCLOSED. ASSET PURCHASE AGREEMENT This ASSET PURCHASE AGREEMENT (this “Agreement”), dated as of February 8, 2024 (the “Effective Date”), is by and among AMERICAN FUEL RESOURCES, LLC, a

November 13, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file numbe

August 11, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-

July 18, 2023 8-K

UNITED STATES

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 12, 2023 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commission Fi

May 24, 2023 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☑ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☑ Defin

May 24, 2023 DEFA14A

United States Securities and Exchange Commission Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

International Isotopes Inc. United States Securities and Exchange Commission Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted

May 15, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNATION

May 10, 2023 EX-10

Executive Employment Agreement, dated December 23, 2022, between the Company and Shahe Bagerdjian (as amended)

Exhibit 10.1 Exhibit 10.1 EXECUTIVE EMPLOYMENT AGREEMENT This EMPLOYMENT AGREEMENT (this “Agreement”) is made and entered into effective as of the execution date of this Agreement (the “Effective Date”) by and between International Isotopes, Inc. (the “Company”), and Shahe Bagerdjian (“Executive”). Capitalized terms used but not defined in the body of this Agreement have the meanings assigned to s

May 10, 2023 8-K

UNITED STATES

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 8, 2023 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commission File

May 3, 2023 10-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K/A (Amendment No. 1)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K/A (Amendment No. 1) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For The Transition Period From To Commission file number: 000-22923 INTER

May 1, 2023 SC 13G/A

INIS / International Isotopes Inc. / Kennerman Associates, Inc. - SC 13G/A Passive Investment

    UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549   SCHEDULE 13G   Under the Securities Exchange Act of 1934 (Amendment No.  15)*   INTERNATIONAL ISOTOPES INC.   (Name of Issuer)   Common Stock, $.01 par value   (Title of Class of Securities)   45972C102   (CUSIP Number)   December 31, 2022   (Date of Event which Requires Filing of this Statement)   Check the appropriate

April 6, 2023 EX-10

Lease Agreement (4137 Commerce Circle), dated January 20, 2020, between the Company and Adrian Rand Robison and Dorothy Robison.

Exhibit 10.3 Exhibit 10.3

April 6, 2023 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 o TRANSITION REPORT PURSUANT TO SECTI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 000-22923 INTERNATIONAL ISOTOPES IN

April 6, 2023 EX-21

Subsidiary list.

Exhibit 21.1 Exhibit 21.1 SUBSIDIARY LIST Name of Subsidiary State Incorporation International Isotopes Idaho Inc. Idaho International Isotopes Fluorine Products Inc. Idaho International Isotopes Transportation Services Inc. Idaho RadQual, LLC Idaho TI Services, LLC Ohio

March 31, 2023 NT 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING (Check One): x Form 10-K o Form 20-F o Form 11-K o Form 10-Q o Form 10-D o Form N-SAR o Form N-CSR For period ended: December 31, 2022 o Transition Report on Form 10-K o Transition Report on Form 20-F o Transition Report on Form 11-K o Transition Report on Form 10-Q o Transition Report o

February 28, 2023 8-K

UNITED STATES

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 22, 2023 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commissio

February 28, 2023 EX-10

Modification #3 to the Amended and Restated Employment Agreement, dated February 22, 2023, between the Company and Stephen Laflin

Exhibit 10.1 Exhibit 10.1 MODIFICATION #3 TO THE AMENDED AND RESTATED EMPLOYMENT AGREEMENT THIS MODIFICATION #3 is made to the Amended and Restated Employment Agreement that was made effective on February 29, 2012 by and between INTERNATIONAL ISOTOPES INC., a public corporation incorporated in the state of Texas (hereinafter “INIS”) and STEPHEN LAFLIN, (hereinafter “Mr. Laflin”). WITNESSETH: WHERE

December 28, 2022 EX-3

Certificate of Amendment to Statement of Designation of the Series C Convertible Redeemable Preferred Stock International Isotopes Inc., dated December 28, 2022 (incorporated by reference to Exhibit 3.1 of the Company’s Current Report on Form 8-K filed December 28, 2022).

Exhibit 3.1 CERTIFICATE OF AMENDMENT TO STATEMENT OF DESIGNATION OF THE SERIES C CONVERTIBLE REDEEMABLE PREFERRED STOCK OF INTERNATIONAL ISOTOPES INC. (Pursuant to Sections 21.155, 21.156, and 21.364 of the Texas Business Organizations Code) INTERNATIONAL ISOTOPES INC. (File No. 137545000), a corporation organized under the Texas Business Corporation Act and existing under the Texas Business Organ

December 28, 2022 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Material Modification to Rights of Security Holders, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 28, 2022 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commissio

November 14, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNA

August 15, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNATIONA

July 19, 2022 8-K

Submission of Matters to a Vote of Security Holders

8-K 1 inis8k071922.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 12, 2022 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of In

May 20, 2022 DEFA14A

United States Securities and Exchange Commission Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEFA14A 1 inisdefa14a052022.htm DEFA14A United States Securities and Exchange Commission Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (a

May 16, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNATION

May 2, 2022 SC 13G/A

INIS / International Isotopes Inc. / Kennerman Associates, Inc. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 14)* INTERNATIONAL ISOTOPES INC. (Name of Issuer) Common Stock, $.01 par value (Title of Class of Securities) 45972C102 (CUSIP Number) December 31, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule p

May 2, 2022 DEF 14A

United States Securities and Exchange Commission Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEF 14A 1 inisdef14a050122.htm DEF 14A United States Securities and Exchange Commission Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as

March 31, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 o TRANSITION REPORT PURSUANT TO SECTI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 000-22923 INTERNATIONAL ISOTOPES IN

February 22, 2022 EX-3

Certificate of Amendment to Statement of Designation of the Series C Convertible Redeemable Preferred Stock International Isotopes Inc., dated February 16, 2022

Exhibit 3.1 CERTIFICATE OF AMENDMENT TO STATEMENT OF DESIGNATION OF THE SERIES C CONVERTIBLE REDEEMABLE PREFERRED STOCK OF INTERNATIONAL ISOTOPES INC. (Pursuant to Sections 21.155, 21.156, and 21.364 of the Texas Business Organizations Code) INTERNATIONAL ISOTOPES INC. (File No. 137545000), a corporation organized under the Texas Business Corporation Act and existing under the Texas Business Organ

February 22, 2022 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Entry into a Material Definitive Agreement, Material Modification to Rights of Security Holders, Financial Statements and Exhibits, Completion of Acquisition or Disposition of Assets

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 16, 2022 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commissio

February 16, 2022 EX-2

Asset Purchase Agreement, dated February 10, 2022, between International Isotopes Inc. and Pharmalogic Idaho, LLC

Exhibit 2.1 ASSET PURCHASE AGREEMENT This ASSET PURCHASE AGREEMENT (this ?Agreement?), dated as of February 10, 2022, is by and between PHARMALOGIC IDAHO, LLC, a Delaware limited liability company (?Buyer?), and INTERNATIONAL ISOTOPES, INC., a Texas corporation (?Seller?). RECITALS: A. Seller owns and operates a contract manufacturing facility located in Idaho Falls, Idaho, including the tangible

February 16, 2022 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 10, 2022 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commissio

November 12, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNA

August 16, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 000-22923 INTERNATIO

July 14, 2021 EX-99

INTERNATIONAL ISOTOPES INC. ANNOUNCES IT HAS ACQUIRED FULL OWNERSHIP OF RADQUAL LLC

Exhibit 99.1 FOR IMMEDIATE RELEASE: July 12, 2021 INTERNATIONAL ISOTOPES INC. ANNOUNCES IT HAS ACQUIRED FULL OWNERSHIP OF RADQUAL LLC IDAHO FALLS, IDAHO, July 12, 2021. International Isotopes Inc. (OTCQB: INIS) (the ?Company?) is pleased to announce it has acquired the remaining 75% of all outstanding units of RadQual LLC (?RadQual?) from a group of affiliates of the Company, including the current

July 14, 2021 EX-2

Membership Interest Purchase Agreement, dated July 8, 2021, between RadQual, LLC, International Isotopes Inc., and each of the sellers named therein

Exhibit 2.1 MEMBERSHIP INTEREST PURCHASE AGREEMENT This Membership Interest Purchase Agreement (this ?Agreement?), dated as of July 8, 2021, is entered into by and among RadQual, LLC, an Idaho limited liability company (?Company?), International Isotopes Inc., a Texas corporation (?Buyer?), and each of the Persons listed as ?Sellers? on Schedule 2.1 attached hereto (each, individually a ?Seller? a

July 14, 2021 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits, Completion of Acquisition or Disposition of Assets, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 8, 2021 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 17, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2021 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNATION

April 30, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 13)*

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 13)* INTERNATIONAL ISOTOPES INC. (Name of Issuer) Common Stock, $.01 par value (Title of Class of Securities) 45972C102 (CUSIP Number) December 31, 2020 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule p

April 30, 2021 DEF 14A

- DEF 14A

United States Securities and Exchange Commission Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) x Defin

March 30, 2021 10-K

Annual Report - 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2020 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 000-22923 INTERNATIONAL ISOTOPES IN

February 9, 2021 S-8

- S-8

S-8 1 iniss8020921.htm S-8 As filed with the Securities and Exchange Commission on February 9, 2021 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 INTERNATIONAL ISOTOPES INC. (Exact name of registrant as specified in its charter) Texas 74-2763837 (State or other jurisdiction of incorpora

December 28, 2020 8-K

Termination of a Material Definitive Agreement - 8-K

International Isotopes Inc. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 21, 2020 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction

November 16, 2020 10-Q

Quarterly Report - 10-Q

International Isotopes Inc. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2020 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission

August 14, 2020 10-Q

Quarterly Report - 10-Q

10-Q 1 inis10q063020.htm 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2020 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission fil

July 21, 2020 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

8-K 1 inis8k072120.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 14, 2020 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of In

July 21, 2020 EX-10.1

International Isotopes Inc. Amended and Restated Employee Stock Purchase Plan

Exhibit 10.1 Exhibit 10.1 INTERNATIONAL ISOTOPES INC. AMENDED AND RESTATED EMPLOYEE STOCK PURCHASE PLAN (effective July 14, 2020) ARTICLE 1. PURPOSE The purpose of this Plan is to provide employees of the Company and its Designated Subsidiaries with an opportunity to purchase Common Stock of the Company. It is the intention of the Company to have the Plan qualify as an "employee stock purchase pla

May 20, 2020 10-Q

Quarterly Report - 10-Q

10-Q 1 inis10q033120.htm 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2020 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission fi

May 15, 2020 NT 10-Q

- NT 10-Q

International Isotopes Inc. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING SEC File Number: 000-22923 CUSIP Number: 45972C102 (Check One): o Form 10-K o Form 20-F o Form 11-K x Form 10-Q o Form 10-D o Form N-SAR o Form N-CSR For period ended: March 31, 2020 o Transition Report on Form 10-K o Transition Report on Form 20-F o Transitio

April 29, 2020 SC 13G/A

INIS / International Isotopes, Inc. / Kennerman Associates, Inc. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 12)* INTERNATIONAL ISOTOPES INC. (Name of Issuer) Common Stock, $.01 par value (Title of Class of Securities) 45972C102 (CUSIP Number) December 31, 2019 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule p

April 29, 2020 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

International Isotopes Inc. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 23, 2020 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of

April 29, 2020 DEF 14A

- DEF 14A

International Isotopes Inc. United States Securities and Exchange Commission Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted

April 29, 2020 EX-10

Loan Agreement and Promissory Note, effective April 22, 2020, between International Isotopes Idaho Inc. and KeyBank National Association

Exhibit 10.1

March 30, 2020 10-K

INIS / International Isotopes, Inc. 10-K - Annual Report - 10-K

International Isotopes Inc. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2019 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 000-229

February 13, 2020 EX-99.1

INTERNATIONAL ISOTOPES INC. ANNOUNCES U.S. FOOD AND DRUG ADMINISTRATION APPROVAL OF THEIR ANDA FOR SODIUM IODIDE I-131

Exhibit 99.1 Exhibit 99.1 FOR IMMEDIATE RELEASE: February 10, 2020 INTERNATIONAL ISOTOPES INC. ANNOUNCES U.S. FOOD AND DRUG ADMINISTRATION APPROVAL OF THEIR ANDA FOR SODIUM IODIDE I-131 Idaho Falls, ID. February 10, 2020 – International Isotopes Inc. (OTCQB: INIS) (the “Company”) is pleased to announce it has received approval from the U.S. Food and Drug Administration (FDA) for its SODIUM IODIDE

February 13, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

International Isotopes Inc. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 10, 2020 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction

January 6, 2020 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

International Isotopes Inc. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 30, 2019 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction

November 14, 2019 10-Q

INIS / International Isotopes, Inc. 10-Q - Quarterly Report -

10-Q 1 inis10q093019.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2019 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission fil

September 27, 2019 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

International Isotopes Inc. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 23, 2019 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction

August 14, 2019 10-Q

INIS / International Isotopes, Inc. 10-Q - Quarterly Report - 10-Q

10-Q 1 inis10q063019.htm 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2019 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission fil

July 18, 2019 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 16, 2019 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commission Fi

May 15, 2019 EX-10.1

Manufacturing and Supply Agreement, dated April 5, 2019, between International Isotopes Inc. and Progenics Pharmaceuticals, Inc.

Exhibit 10.1 Exhibit 10.1 PORTIONS OF THIS EXHIBIT MARKED BY [**] HAVE BEEN OMITTED PURSUANT TO RULE 601(B)(10) OF REGULATION S-K. THE OMITTED INFORMATION IS (I) NOT MATERIAL AND (II) WOULD LIKELY CAUSE COMPETITIVE HARM TO THE REGISTRANT IF PUBLICLY DISCLOSED. MANUFACTURING AND SUPPLY AGREEMENT BETWEEN INTERNATIONAL ISOTOPES INC. AND PROGENICS PHARMACEUTICALS, INC. Dated as of April 5, 2019 MANUFA

May 15, 2019 10-Q

INIS / International Isotopes, Inc. 10-Q Quarterly Report 10-Q

10-Q 1 inis10q033119.htm 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2019 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission fi

April 30, 2019 DEF 14A

INIS / International Isotopes, Inc. DEF 14A DEF 14A

International Isotopes Inc. United States Securities and Exchange Commission Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted

April 26, 2019 SC 13G/A

INIS / International Isotopes, Inc. / Kennerman Associates, Inc. - SC 13G/A Passive Investment

SC 13G/A 1 a19-89791sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 11)* INTERNATIONAL ISOTOPES INC. (Name of Issuer) Common Stock, $.01 par value (Title of Class of Securities) 45972C102 (CUSIP Number) December 31, 2018 (Date of Event Which Requires Filing of this Statement) Check the

April 11, 2019 8-K

Entry into a Material Definitive Agreement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 5, 2019 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commission Fi

March 22, 2019 10-K/A

INIS / International Isotopes, Inc. 10-K/A (Annual Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K/A (Amendment No. 1) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2018 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 000-22923 INTER

March 19, 2019 10-K

INIS / International Isotopes, Inc. 10-K (Annual Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2018 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 000-22923 INTERNATIONAL ISOTOPES IN

November 19, 2018 8-K

Financial Statements and Exhibits, Changes in Registrant's Certifying Accountant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 16, 2018 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commissio

November 19, 2018 EX-16

Letter from Eide Bailly LLP, dated November 19, 2018

Exhibit 16.1 November 19, 2018 Securities and Exchange Commission 100 F Street Washington, DC 20549 Ladies and Gentlemen: On November 16, 2018, we were informed that we had been dismissed as the independent registered public accounting firm for International Isotopes, Inc. (the Company). We have read the Company’s disclosure set forth in Item 4.01, “Changes in Registrant’s Certifying Accountant” o

November 14, 2018 S-8

INIS / International Isotopes, Inc. S-8

S-8 1 iniss8110918.htm S-8 As filed with the Securities and Exchange Commission on November 14, 2018 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 INTERNATIONAL ISOTOPES INC. (Exact name of registrant as specified in its charter) Texas 74-2763837 (State or other jurisdiction of incorpor

November 14, 2018 10-Q

INIS / International Isotopes, Inc. 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2018 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNA

August 14, 2018 10-Q

INIS / International Isotopes, Inc. 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2018 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNATIONA

July 30, 2018 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 24, 2018 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commission Fi

July 30, 2018 EX-10

International Isotopes Inc. Amended and Restated 2015 Incentive Plan

Exhibit 10.1 INTERNATIONAL ISOTOPES INC. AMENDED AND RESTATED 2015 INCENTIVE PLAN (As Amended and Restated on July 24, 2018) SECTION 1. PURPOSE This International Isotopes Inc. 2015 Incentive Plan is an amendment and restatement of the International Isotopes Inc. 2006 Equity Incentive Plan. The purpose of the International Isotopes Inc. 2015 Incentive Plan is to attract, retain and motivate employ

May 18, 2018 10-Q

INIS / International Isotopes, Inc. 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2018 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNATION

May 16, 2018 NT 10-Q

INIS / International Isotopes, Inc. NT 10-Q

NT 10-Q 1 inisnt10q033118.htm NT 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING SEC File Number: 000-22923 CUSIP Number: 45972C102 (Check One): o Form 10-K o Form 20-F o Form 11-K x Form 10-Q o Form 10-D o Form N-SAR o Form N-CSR For period ended: March 31, 2018 o Transition Report on Form 10-K o Transition Report on Form 20-F o

April 30, 2018 DEF 14A

INIS / International Isotopes, Inc. DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) x Defin

April 20, 2018 PRE 14A

INIS / International Isotopes, Inc. PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: x Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Defin

April 20, 2018 SC 13G/A

INIS / International Isotopes, Inc. / Kennerman Associates, Inc. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 10)* INTERNATIONAL ISOTOPES INC. (Name of Issuer) Common Stock, $.01 par value (Title of Class of Securities) 45972C102 (CUSIP Number) December 31, 2017 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule p

March 30, 2018 10-K

INIS / International Isotopes, Inc. 10-K (Annual Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2017 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 000-22923 INTERNATIONAL ISOTOPES IN

November 14, 2017 10-Q

INIS / International Isotopes, Inc. 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2017 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNA

August 14, 2017 10-Q

INIS / International Isotopes, Inc. 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2017 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNATIONA

August 8, 2017 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 2, 2017 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of

July 17, 2017 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Submission of Matters to a Vote of Security Holders

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 11, 2017 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of I

May 18, 2017 EX-4

Form of Class N Warrant

Exhibit 4.1 Exhibit 4.1 NEITHER THIS WARRANT NOR THE SECURITIES INTO WHICH THIS WARRANT IS EXERCISABLE HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR APPLICABLE STATE SECURITIES LAWS. THIS WARRANT AND THE SECURITIES INTO WHICH THIS WARRANT IS EXERCISABLE HAVE BEEN ACQUIRED FOR INVESTMENT AND MAY NOT BE OFFERED FOR SALE, SOLD, TRANSFERRED OR ASSIGNED IN THE ABSENCE OF AN EFFE

May 18, 2017 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits

8-K 1 inis8k051817.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): May 12, 2017 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorpo

May 15, 2017 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

10-Q 1 inis10q033117.htm 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2017 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission fi

May 10, 2017 EX-10

First Modification to Cobalt-60 Pellet Supply Agreement, effective April 21, 2017, between International Isotopes Inc. and Nordion (Canada) Inc., as general partner of and on behalf of Nordion Sterilization LP

Exhibit 10.1 Exhibit 10.1 CONFIDENTIAL TREATMENT HAS BEEN REQUESTED FOR THE REDACTED PORTIONS OF THIS EXHIBIT. THE REDACTIONS ARE INDICATED WITH ?[**]?. A COMPLETE VERSION OF THIS EXHIBIT HAS BEEN FILED WITH THE U.S. SECURITIES AND EXCHANGE COMMISSION. First Modification To COBALT-60 PELLET SUPPLY AGREEMENT April 21, 2017 This is the first modification, effective as of the date set out above (the

May 10, 2017 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): May 4, 2017 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commission File Num

May 1, 2017 DEF 14A

International Isotopes DEF 14A

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted

May 1, 2017 SC 13G/A

INIS / International Isotopes, Inc. / Kennerman Associates, Inc. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 9)* INTERNATIONAL ISOTOPES INC. (Name of Issuer) Common Stock, $.01 par value (Title of Class of Securities) 45972C102 (CUSIP Number) December 31, 2016 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pu

March 31, 2017 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2016 o TRANSITION REPORT PURSUANT TO SECTI

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2016 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 000-229

March 31, 2017 EX-15

Modification #1 to the Amended and Restated Employment Agreement, dated October 12, 2016, between the Company and Stephen Laflin

Exhibit 10.15 MODIFICATION #1 TO THE AMENDED AND RESTATED EMPLOYMENT AGREEMENT THIS MODIFICATION #1 is made to the Amended and Restated Employment Agreement that was made effective on February 29, 2012 by and between INTERNATIONAL ISOTOPES INC., a public corporation incorporated in the state of Texas (hereinafter "INIS") and ST'EPHEN LAFLIN, (hereinafter "Mr. Laflin"). WITNESSETH: WHEREAS, The ter

March 31, 2017 EX-10

Modification #1 to the Gemstone Processing Agreement, dated November 28, 2016, between the Company and QualiTech, Inc.

Exhibit 10.9 MODIFICATION #1 TO THE AGREEMENT This Modification #1 to the GEMSTONE PROCESSING AGREEMENT ("The Agreement") made and entered into by and between QUALI-TECH INC. (HEREAFTER "QTI"), and INTERNATIONAL ISOTOPES INC. (hereafter "INIS") WITNESSETH. WHEREAS, INIS has requested an adjustment to the Processing Charge and implementation of an annual inflationary index to make further adjustmen

March 31, 2017 EX-18

Modification #2 to the Promissory Note Agreement, dated February 3, 2017, among the Company, Ralph M. Richart and John M. McCormack

Exhibit 10.18 MODIFICATION #2 TO THE PROMISSORY NOTE AGREEMENT THIS MODIFICATION #2 TO THE PROMISSORY NOTE AGREEMENT (The "Agreement") made and entered into by and between Ralph M. Richart and John M. McCormack (The "Lenders") and International Isotopes Inc. (hereafter "Company", "Borrower", or "INIS") on December 23, 2013. WITNESSETH: WHEREAS, the Lenders have agreed to modify the maturity date f

March 30, 2017 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): March 24, 2017 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Inco

March 30, 2017 EX-10

Amendment to 8% Convertible Notes, dated March 24, 2017, between Euro Pacific Capital Inc. and they Company (incorporated by reference to Exhibit 10.1 of the Company’s Current Report on Form 8-K filed on March 30, 2017)

Exhibit 10.1 Exhibit 10.1 AMENDMENT TO 8% CONVERTIBLE NOTES This Amendment to 8% Convertible Notes (this ?Agreement?) is dated as of March 24, 2017 by and between Euro Pacific Capital Inc. (?Euro Pacific Capital?) and International Isotopes Inc. (the ?Company?). RECITALS WHEREAS, on July 27, 2012, the Company issued to certain holders 8% Convertible Notes in the aggregate principal amount of up to

February 24, 2017 EX-4

Form of Class M Warrant

Exhibit 4.1 Exhibit 4.1 NEITHER THIS WARRANT NOR THE SECURITIES INTO WHICH THIS WARRANT IS EXERCISABLE HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR APPLICABLE STATE SECURITIES LAWS. THIS WARRANT AND THE SECURITIES INTO WHICH THIS WARRANT IS EXERCISABLE HAVE BEEN ACQUIRED FOR INVESTMENT AND MAY NOT BE OFFERED FOR SALE, SOLD, TRANSFERRED OR ASSIGNED IN THE ABSENCE OF AN EFFE

February 24, 2017 EX-10

Registration Rights Agreement, dated February 17, 2017, among the Company and the purchasers named therein

Exhibit 10.1 Exhibit 10.1 INTERNATIONAL ISOTOPES INC. REGISTRATION RIGHTS AGREEMENT REGISTRATION RIGHTS AGREEMENT, dated as of February 17, 2017 (the ?Agreement?), between INTERNATIONAL ISOTOPES INC., a Texas corporation (the ?Company?), and each purchaser identified on Schedule A hereto (each, including their respective successors and assigns, an ?Investor? and collectively, the ?Investors?). NOW

February 24, 2017 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): February 17, 2017 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of I

February 24, 2017 EX-3

Statement of Designation of the Series C Convertible Redeemable Preferred Stock of International Isotopes Inc.

Exhibit 3.1 Exhibit 3.1 STATEMENT OF DESIGNATION OF THE SERIES C CONVERTIBLE REDEEMABLE PREFERRED STOCK OF INTERNATIONAL ISOTOPES INC. (Pursuant to Section 21.155 of the Texas Business Organizations Code) International Isotopes Inc., a corporation organized under the Texas Business Corporation Act and existing under the Texas Business Organizations Code (the ?Company?), DOES HEREBY CERTIFY that (a

November 21, 2016 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): November 21, 2016 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of I

November 21, 2016 EX-99

INTERNATIONAL ISOTOPES INC. SUBMITS ABBREVIATED NEW DRUG APPLICATION FOR SODIUM IODIDE I-131 The Company’s I3odine/MAXTM Product Is The First Generic Drug Application Submitted To The FDA For Sodium Iodide Oral Solution Or Capsules

Exhibit 99.1 Exhibit 99.1 FOR IMMEDIATE RELEASE: November 21, 2016 INTERNATIONAL ISOTOPES INC. SUBMITS ABBREVIATED NEW DRUG APPLICATION FOR SODIUM IODIDE I-131 The Company?s I3odine/MAXTM Product Is The First Generic Drug Application Submitted To The FDA For Sodium Iodide Oral Solution Or Capsules Idaho Falls, ID. November 21, 2016 ? International Isotopes Inc. (OTCQB: INIS) (the ?Company?) announ

November 14, 2016 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2016 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNA

August 12, 2016 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2016 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNATIONA

July 14, 2016 8-K

Submission of Matters to a Vote of Security Holders

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 12, 2016 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of I

May 13, 2016 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2016 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNATION

April 29, 2016 DEF 14A

International Isotopes DEF 14A

DEF 14A 1 inisdef14a042816.htm DEF 14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as

April 28, 2016 SC 13G/A

INIS / International Isotopes, Inc. / Kennerman Associates, Inc. - SC 13G/A Passive Investment

SC 13G/A 1 a16-98711sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 8)* INTERNATIONAL ISOTOPES INC. (Name of Issuer) Common Stock, $.01 par value (Title of Class of Securities) 45972C102 (CUSIP Number) December 31, 2015 (Date of Event Which Requires Filing of this Statement) Check the

March 28, 2016 EX-99

INTERNATIONAL ISOTOPES INC. ANNOUNCES 2015 4TH QUARTER AND YEAR END FINANCIAL RESULTS The Company completes its second year in a row of positive cash flow from operating activities

Exhibit 99.1 Exhibit 99.1 FOR IMMEDIATE RELEASE: March 28, 2016 INTERNATIONAL ISOTOPES INC. ANNOUNCES 2015 4TH QUARTER AND YEAR END FINANCIAL RESULTS The Company completes its second year in a row of positive cash flow from operating activities IDAHO FALLS, IDAHO, March 28, 2016. International Isotopes Inc. (OTCQB: INIS) (the ?Company?) announces its financial results for the 4th quarter and fisca

March 28, 2016 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): March 28, 2016 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of

March 24, 2016 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2015 o TRANSITION REPORT PURSUANT TO SECTI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2015 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 000-22923 INTERNATIONAL ISOTOPES IN

November 13, 2015 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2015 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNA

August 14, 2015 S-8

International Isotopes S-8

As filed with the Securities and Exchange Commission on August 14, 2015 Registration No.

August 14, 2015 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2015 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNATIONA

August 14, 2015 EX-10

Cobalt-60 Pellet Supply Agreement, dated April 7, 2015, between Nordion (Canada) Inc., as general partner of and on behalf of Nordion Sterilization LP, and International Isotopes Inc.

Exhibit 10.1 CONFIDENTIAL TREATMENT HAS BEEN REQUESTED FOR THE REDACTED PORTIONS OF THIS EXHIBIT. THE REDACTIONS ARE INDICATED WITH ?[**]?. A COMPLETE VERSION OF THIS EXHIBIT HAS BEEN FILED WITH THE U.S. SECURITIES AND EXCHANGE COMMISSION. COBALT-60 PELLET SUPPLY AGREEMENT THIS AGREEMENT is made effective as of this 7th day of April, 2015, by and between Nordion (Canada) Inc. as general partner of

July 16, 2015 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): July 14, 2015 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of I

July 16, 2015 EX-10

International Isotopes Inc. 2015 Incentive Plan (incorporated by reference to Exhibit 10.1 of the Company’s Current Report on Form 8-K, filed on July 16, 2015)

Exhibit 10.1 INTERNATIONAL ISOTOPES INC. 2015 INCENTIVE PLAN SECTION 1. PURPOSE This International Isotopes Inc. 2015 Incentive Plan is an amendment and restatement of the International Isotopes Inc. 2006 Equity Incentive Plan. The purpose of the International Isotopes Inc. 2015 Incentive Plan is to attract, retain and motivate employees, officers, directors, consultants, agents, advisors and inde

May 15, 2015 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2015 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNATION

April 30, 2015 DEF 14A

International Isotopes DEF 14A

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted

April 14, 2015 8-K

Entry into a Material Definitive Agreement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): April 8, 2015 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commission Fi

April 1, 2015 SC 13G/A

INIS / International Isotopes, Inc. / Kennerman Associates, Inc. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 7)* INTERNATIONAL ISOTOPES INC. (Name of Issuer) Common Stock, $.01 par value (Title of Class of Securities) 45972C102 (CUSIP Number) December 31, 2014 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pu

March 31, 2015 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2014 o TRANSITION REPORT PURSUANT TO SECTI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2014 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 000-22923 INTERNATIONAL ISOTOPES IN

March 31, 2015 EX-10

Isotope and Technical Service Order Form, dated October 2, 2014, between the Company and the U.S. Department of Energy

Converted by EDGARwiz

February 26, 2015 8-K

Unregistered Sales of Equity Securities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): February 20, 2015 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commissio

November 14, 2014 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2014 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNA

October 6, 2014 8-K

Entry into a Material Definitive Agreement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): October 2, 2014 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commission

August 8, 2014 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2014 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNATIONA

August 8, 2014 EX-10

Modification #1 to the Promissory Note Agreement, dated June 30, 2014, among the Company, Ralph M. Richart and John M. McCormack

Exhibit 10.1 MODIFICATION #1 TO THE PROMISSORY NOTE AGREEMENT THIS MODIFICATION #1 TO THE PROMISSORY NOTE AGREEMENT (The ?Agreement?) made and entered into by and between Ralph M. Richart and John M. McCormack (The ?Lenders?) and International Isotopes Inc. (hereafter ?Company?, ?Borrower?, or ?INIS?) on June 30, 2014. WITNESSETH: WHEREAS, the Lenders have agreed to modify the maturity date for th

July 21, 2014 8-K

Submission of Matters to a Vote of Security Holders

Converted by EDGARwiz UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

May 14, 2014 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2014 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNATION

April 29, 2014 DEF 14A

- DEF 14A

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted

March 28, 2014 EX-10

Promissory Note Agreement, dated December 23, 2013, among the Company, Ralph Richart and John McCormack

Exhibit 10.19 Exhibit 10.19 PROMISSORY NOTE AGREEMENT THIS PROMISSORY NOTE AGREEMENT (this “Agreement”), is made and entered into as of December 23, 2013, by and between the undersigned lenders (“Lenders”) and International Isotopes Inc., a Texas corporation (“Borrower”). WITNESSETH: WHEREAS, Borrower desires to borrow from Lenders, and Lenders are willing to loan to Borrower, the principal amount

March 28, 2014 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2013 o TRANSITION REPORT PURSUANT TO SECTI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2013 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 000-22923 INTERNATIONAL ISOTOPES IN

March 28, 2014 EX-4

Form of Class L Warrant (incorporated by reference to Exhibit 4.10 of the Company’s Annual Report on Form 10-K for the year ended December 31, 2013)

Exhibit 4.10 NEITHER THIS WARRANT NOR THE SECURITIES INTO WHICH THIS WARRANT IS EXERCISABLE HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR APPLICABLE STATE SECURITIES LAWS. THIS WARRANT AND THE SECURITIES INTO WHICH THIS WARRANT IS EXERCISABLE HAVE BEEN ACQUIRED FOR INVESTMENT AND MAY NOT BE OFFERED FOR SALE, SOLD, TRANSFERRED OR ASSIGNED IN THE ABSENCE OF AN EFFECTIVE REGIS

March 20, 2014 SC 13G/A

INIS / International Isotopes, Inc. / Kennerman Associates, Inc. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 6)* INTERNATIONAL ISOTOPES INC. (Name of Issuer) Common Stock, $.01 par value (Title of Class of Securities) 45972C102 (CUSIP Number) December 31, 2013 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pu

December 20, 2013 SC 13D/A

INIS / International Isotopes, Inc. / Firebird Global Master Fund II, Ltd. - SCHEDULE 13D AMENDMENT NO.8 Activist Investment

Schedule 13D Amendment No.8 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 8)* International Isotopes Inc. (Name of Issuer) Common Stock, par value $0.01 per share (Title of Class of Securities) 45972C102 (CUSIP Number) Joanne Tuckman Chief Financial Officer FG2 Advisors, LLC 152 West 57th Street, 24th F

December 20, 2013 EX-1

JOINT FILING AGREEMENT

EX-1 Exhibit 1 JOINT FILING AGREEMENT Firebird Global Master Fund II, Ltd., FG2 Advisors, LLC, James Passin, and Harvey Sawikin, in compliance with Rule 13d-1(k) of the Securities and Exchange Commission, hereby agree that the statement on Schedule 13D to which this Agreement is attached as an exhibit is, and any amendments thereto filed by any of us will be, filed on behalf of each such person or

November 14, 2013 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2013 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNA

October 8, 2013 8-K

Other Events - 8-K

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 4, 2013 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of

September 6, 2013 EX-16

HANSEN, BARNETT & MAXWELL, P.C.

Exhibit 16.1 H B M HANSEN, BARNETT & MAXWELL, P.C. Certified Public Accountants September 6, 2013 Securities and Exchange Commission 450 5th Street NW Washington, DC 20549 Ladies and Gentlemen: We have read the statements of International Isotopes, Inc., included under Item 4.01 of Form 8-K, with respect to this firm’s resignation as the registered independent accounting firm of International Isot

September 6, 2013 8-K

Financial Statements and Exhibits, Changes in Registrant's Certifying Accountant - 8-K

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): September 1, 2013 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction

August 14, 2013 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2013 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNATIONA

July 18, 2013 8-K

Submission of Matters to a Vote of Security Holders - 8-K

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): July 16, 2013 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of I

May 14, 2013 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2013 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 0-22923 INTERNATION

April 29, 2013 DEF 14A

- DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) x Defin

April 8, 2013 EX-99

INTERNATIONAL ISOTOPES INC. AND ADVANCED PROCESS TECHNOLOGY SYSTEMS, LLC ANNOUNCE SUBMISSION OF AN EXPRESSION OF INTEREST FOR THE OPERATION OF THE PADUCAH GASEOUS DIFFUSION PLANT The Companies Propose to Form a New Joint Venture In a Proposal to Oper

Exhibit 99.1 And FOR IMMEDIATE RELEASE: April 8, 2013 INTERNATIONAL ISOTOPES INC. AND ADVANCED PROCESS TECHNOLOGY SYSTEMS, LLC ANNOUNCE SUBMISSION OF AN EXPRESSION OF INTEREST FOR THE OPERATION OF THE PADUCAH GASEOUS DIFFUSION PLANT The Companies Propose to Form a New Joint Venture In a Proposal to Operate the Paducah Gaseous Diffusion Plant Idaho Falls, ID. April 8, 2013 – International Isotopes

April 8, 2013 8-K

Regulation FD Disclosure, Financial Statements and Exhibits - 8-K

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): April 8, 2013 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of I

March 28, 2013 EX-10

MODIFICATION #4 THE UNSECURED NOTE AGREEMENT

Exhibit 10.12 Exhibit 10.12 MODIFICATION #4 TO THE UNSECURED NOTE AGREEMENT THIS MODIFICATION #4 TO THE AGREEMENT made and entered into by and between WILLIAM NICHOLSON and INTERNATIONAL ISOTOPES INC. (hereafter “Company” or “INIS”) WITNESSETH: WHEREAS, WILLIAM NICHOLSON has agreed to modify the repayment schedule for the balance of the unsecured note, and WHEREAS, INIS is willing to accept the mo

March 28, 2013 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2012 o TRANSITION REPORT PURSUANT TO SECTI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2012 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 000-22923 INTERNATIONAL ISOTOPES IN

February 26, 2013 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - 8-K

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant To Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 20, 2013 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction

February 26, 2013 EX-2

SECURITIES PURCHASE AGREEMENT

Exhibit 2.1 Exhibit 2.1 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of February 20, 2013 among International Isotopes Inc., a Texas corporation (the “Company”), and the purchasers identified on the signature pages hereto (each, a “Purchaser” and collectively, the “Purchasers”). WHEREAS, subject to the terms and conditions set forth in this Agreem

February 26, 2013 EX-4

CONVERTIBLE DEBENTURE DUE FEBRUARY 20, 2015

Exhibit 4.1 Exhibit 4.1 NEITHER THIS SECURITY NOR THE SECURITIES INTO WHICH THIS SECURITY IS CONVERTIBLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFE

February 11, 2013 SC 13G/A

INIS / International Isotopes, Inc. / Kennerman Associates, Inc. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 5)* INTERNATIONAL ISOTOPES, INC. (Name of Issuer) Common Stock, $.01 par value (Title of Class of Securities) 45972C102 (CUSIP Number) December 31, 2012 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule p

November 13, 2012 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2012 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission

November 13, 2012 EX-10

MODIFICATION #3 THE UNSECURED NOTE AGREEMENT

Exhibit 10.1 MODIFICATION #3 TO THE UNSECURED NOTE AGREEMENT THIS MODIFICATION #3 TO THE AGREEMENT made and entered into by and between WILLIAM NICHOLSON and INTERNATIONAL ISOTOPES INC. (hereafter ?Company? or ?INIS?) WITNESSETH: WHEREAS, WILLIAM NICHOLSON has agreed to modify the repayment schedule for the balance of the unsecured note, and WHEREAS, INIS is willing to accept the modification of t

August 14, 2012 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2012 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file

August 14, 2012 EX-10

MODIFICATION #2 THE UNSECURED NOTE AGREEMENT

Exhibit 10.1 MODIFICATION #2 TO THE UNSECURED NOTE AGREEMENT THIS MODIFICATION #2 TO THE AGREEMENT made and entered into by and between WILLIAM NICHOLSON and INTERNATIONAL ISOTOPES INC. (hereafter ?Company? or ?INIS?) WITNESSETH: WHEREAS, WILLIAM NICHOLSON has agreed to convert a portion of the unsecured note into a convertible debenture private placement being offered by the Company, and conducte

August 14, 2012 EX-10

Amended and Restated Employment Agreement, dated May 16, 2012, between the Company and Stephen Laflin

Exhibit 10.2 INTERNATIONAL ISOTOPES INC AMENDED AND RESTATED EMPLOYMENT AGREEMENT THIS AMENDED AND RESTATED EMPLOYMENT AGREEMENT (as it may be amended or supplemented, this "Agreement") is entered into as of May 16, 2012, effective as of February 29, 2012 (the "Effective Date"), by and between International Isotopes Inc., a Texas corporation ("Company"), and Stephen Laflin. RECITALS A. Company des

August 2, 2012 EX-99

INTERNATIONAL ISOTOPES INC. 8% CONVERTIBLE NOTE

Exhibit 99.2 Exhibit 99.2 THIS NOTE AND THE SECURITIES ISSUABLE UPON CONVERSION HEREOF HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR APPLICABLE STATE SECURITIES LAWS. THIS NOTE AND THE SECURITIES ISSUABLE UPON CONVERSION HEREOF HAVE BEEN ACQUIRED FOR INVESTMENT AND MAY NOT BE OFFERED FOR SALE, SOLD, TRANSFERRED OR ASSIGNED IN THE ABSENCE OF AN EFFECTIVE REGISTRATION STA

August 2, 2012 EX-99

INTERNATIONAL ISOTOPES INC. REGISTRATION RIGHTS AGREEMENT

Exhibit 99.4 Exhibit 99.4 INTERNATIONAL ISOTOPES INC. REGISTRATION RIGHTS AGREEMENT REGISTRATION RIGHTS AGREEMENT, dated as of July 27, 2012, between INTERNATIONAL ISOTOPES INC., a Texas corporation (the “Company”) and each purchaser identified on Schedule A hereto (each, including their respective successors and assigns, an “Investor” and collectively, the “Investors”). Capitalized terms used, bu

August 2, 2012 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant, Other Events - 8-K

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): July 27, 2012 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of I

August 2, 2012 EX-99

INTERNATIONAL ISOTOPES INC. ANNOUNCES COMPLETION OF A $3 MILLION PRIVATE PLACEMENT Funding Should See the Company Through Receipt of the Nuclear Regulatory Commission License of its Depleted Uranium Project and Facilitate Expansion of the Company’s C

Exhibit 99.5 Exhibit 99.5 FOR IMMEDIATE RELEASE: July 30, 2012 INTERNATIONAL ISOTOPES INC. ANNOUNCES COMPLETION OF A $3 MILLION PRIVATE PLACEMENT Funding Should See the Company Through Receipt of the Nuclear Regulatory Commission License of its Depleted Uranium Project and Facilitate Expansion of the Company’s Core Business Operations Idaho Falls, ID. July 30, 2012 – International Isotopes Inc. (O

August 2, 2012 EX-99

SECURITIES PURCHASE AGREEMENT

Exhibit 99.1 Exhibit 99.1 SECURITIES PURCHASE AGREEMENT This SECURITIES PURCHASE AGREEMENT (this “Agreement”), dated July 27, 2012, is between INTERNATIONAL ISOTOPES INC., a Texas corporation (the “Company”), and each purchaser identified on Schedule A hereto (each, including their respective successors and assigns, an “Investor” and collectively, the “Investors”) and, with respect to certain sect

August 2, 2012 EX-99

INTERNATIONAL ISOTOPES INC. CLASS K COMMON STOCK PURCHASE WARRANT

Exhibit 99.3 Exhibit 99.3 NEITHER THIS WARRANT NOR THE SECURITIES INTO WHICH THIS WARRANT IS EXERCISABLE HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR APPLICABLE STATE SECURITIES LAWS. THIS WARRANT AND THE SECURITIES INTO WHICH THIS WARRANT IS EXERCISABLE HAVE BEEN ACQUIRED FOR INVESTMENT AND MAY NOT BE OFFERED FOR SALE, SOLD, TRANSFERRED OR ASSIGNED IN THE ABSENCE OF AN EF

July 19, 2012 8-K

Submission of Matters to a Vote of Security Holders - 8-K

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): July 17, 2012 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) Texas 0-22923 74-2763837 (State or Other Jurisdiction of I

May 14, 2012 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2012 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file

May 14, 2012 EX-10

MODIFICATION #1 THE UNSECURED NOTE AGREEMENT

EX-10 2 exhibit101.htm EXHIBIT 10.1 Exhibit 10.1 MODIFICATION #1 TO THE UNSECURED NOTE AGREEMENT THIS MODIFICATION #1 TO THE AGREEMENT made and entered into by and between WILLIAM NICHOLSON and INTERNATIONAL ISOTOPES INC. (hereafter “Company” or “INIS) WITNESSETH: WHEREAS, INIS has requested a 7 month extension to the term of the Unsecured Note having an original maturity date of April 1, 2012, an

April 30, 2012 DEF 14A

- DEF 14A

DEF 14A 1 def14a043012.htm DEF 14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Pr

April 20, 2012 PRE 14A

- PRE 14A

PRE 14A 1 pre14a042012.htm PRE 14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: x Pr

April 3, 2012 SC 13G/A

INIS / International Isotopes, Inc. / Kennerman Associates, Inc. - SC 13G/A Passive Investment

SC 13G/A 1 a12-90381sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 4)* INTERNATIONAL ISOTOPES, INC. (Name of Issuer) Common Stock, $.01 par value (Title of Class of Securities) 45972C102 (CUSIP Number) December 31, 2011 (Date of Event Which Requires Filing of this Statement) Check the

March 28, 2012 EX-10

DOE Form

Exhibit 10.23 [***] Indicates confidential material that has been omitted pursuant to a Confidential Treatment Request filed with the Securities and Exchange Commission. A complete copy of this agreement has been separately filed with the Securities and Exchange Commission. DOE Form U.S. DEPARTMENT OF ENERGY CA-10-90.COM Rev 3 ISOTOPE AND TECHNICAL SERVICE ORDER FORM (07/01) This form is to be use

March 28, 2012 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2011 o TRANSITION REPORT PURSUANT TO SECT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2011 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 000-22923 INTERNATIONAL ISOTOPES I

January 10, 2012 424B3

Prospectus Supplement No. 5 (To Prospectus dated July 20, 2011) 59,687,333 Shares Common Stock, par value $0.01

INTERNATIONAL ISOTOPES INC. Filed Pursuant to Rule 424(b)(3) Registration No. 333-171140 Prospectus Supplement No. 5 (To Prospectus dated July 20, 2011) 59,687,333 Shares Common Stock, par value $0.01 This Prospectus Supplement No. 5 supplements the prospectus of International Isotopes Inc. (the “Company”) dated July 20, 2011, as supplemented by Prospectus Supplement No. 1 dated August 10, 2011, P

December 23, 2011 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant To Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 20, 2011 INTERNATIONAL I

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant To Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 20, 2011 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) TEXAS 0-22923 74-2763837 (State or Other Jurisdiction

November 15, 2011 424B3

Prospectus Supplement No. 4 (To Prospectus dated July 20, 2011) 59,687,333 Shares Common Stock, par value $0.01

424B3 1 f424b3111511.htm 424(B)(3) Filed Pursuant to Rule 424(b)(3) Registration No. 333-171140 Prospectus Supplement No. 4 (To Prospectus dated July 20, 2011) 59,687,333 Shares Common Stock, par value $0.01 This Prospectus Supplement No.4 supplements the prospectus of International Isotopes Inc. (the “Company”) dated July 20, 2011, as supplemented by Prospectus Supplement No. 1 dated August 10, 2

November 14, 2011 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

10-Q 1 f10q093011.htm 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2011 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission f

October 5, 2011 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant To Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 30, 2011 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) TEXAS 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commissi

October 5, 2011 424B3

Prospectus Supplement No. 3 to Prospectus dated July 20, 2011, as previously supplemented by Prospectus Supplement No. 1 dated August 10, 2011 and Prospectus Supplement No. 2 dated September 14, 2011. 59,687,333 Shares Common Stock, par value $0.01

Filed Pursuant to Rule 424(b)(3) Registration No. 333-171140 Prospectus Supplement No. 3 to Prospectus dated July 20, 2011, as previously supplemented by Prospectus Supplement No. 1 dated August 10, 2011 and Prospectus Supplement No. 2 dated September 14, 2011. 59,687,333 Shares Common Stock, par value $0.01 This Prospectus Supplement No.3 supplements the prospectus of International Isotopes Inc.

September 14, 2011 8-K

Material Modification to Rights of Security Holders, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant To Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 8, 2011 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) TEXAS 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commissio

September 14, 2011 424B3

Prospectus Supplement No. 2 to Prospectus dated July 20, 2011, as previously supplemented by Prospectus Supplement No. 1 dated August 10, 2011. 59,687,333 Shares Common Stock, par value $0.01

Filed Pursuant to Rule 424(b)(3) Registration No. 333-171140 Prospectus Supplement No. 2 to Prospectus dated July 20, 2011, as previously supplemented by Prospectus Supplement No. 1 dated August 10, 2011. 59,687,333 Shares Common Stock, par value $0.01 This Prospectus Supplement No.2 supplements the prospectus of International Isotopes Inc. (the “Company”) dated July 20, 2011 and Prospectus Supple

August 26, 2011 SC 13D/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 7)* International Isotopes Inc. (Name of Issuer) Common Stock, par value $0.01 per share (Title of Class of

SC 13D/A 1 dsc13da.htm SCHEDULE 13D AMENDMENT NO. 7 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 7)* International Isotopes Inc. (Name of Issuer) Common Stock, par value $0.01 per share (Title of Class of Securities) 45972C102 (CUSIP Number) Joanne Tuckman Chief Financial Officer FG2 Advisors, LLC 152

August 19, 2011 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant To Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 19, 2011 INTERNATIONAL ISO

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant To Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 19, 2011 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) TEXAS 0-22923 74-2763837 (State or Other Jurisdiction of

August 10, 2011 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2011 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission fi

August 10, 2011 424B3

Prospectus Supplement No. 1 to Prospectus dated July 20, 2011 59,687,333 Shares Common Stock, par value $0.01

424B3 1 f424b3081011.htm 424 B3 Filed Pursuant to Rule 424(b)(3) Registration No. 333-171140 Prospectus Supplement No. 1 to Prospectus dated July 20, 2011 59,687,333 Shares Common Stock, par value $0.01 This Prospectus Supplement No.1 supplements the prospectus of International Isotopes Inc. (the “Company”) dated July 20, 2011(the “Prospectus”), relating to the offer and sale of up to 29,075,000 s

August 10, 2011 EX-10

LEASE AGREEMENT (1359 Commerce Circle)

Exhibit 10.2 LEASE AGREEMENT (1359 Commerce Circle) THIS LEASE AGREEMENT, is made and entered into as of this 1st day of May, 2011, by and between ADRIAN RAND ROBISON and DOROTHY ROBISON, husband and wife, referred to herein as "Lessor", and INTERNATIONAL ISOTOPES, INC., a Texas corporation, referred to herein as "Lessee". WITNESSETH: In consideration of the mutual covenants, conditions and agreem

August 10, 2011 EX-10

Lease Agreement (4137 Commerce Circle), dated May 1, 2011, between the Company and Adrian Rand Robison and Dorothy Robison (incorporated by reference to Exhibit 10.1 of the Company’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2011)

Exhibit 10.1 LEASE AGREEMENT (4137 Commerce Circle) THIS LEASE AGREEMENT, is made and entered into as of this 1st day of May, 2011, by and between ADRIAN RAND ROBISON and DOROTHY ROBISON, husband and wife, referred to herein as "Lessor", and INTERNATIONAL ISOTOPES, INC., a Texas corporation, referred to herein as "Lessee". WITNESSETH: In consideration of the mutual covenants, conditions and agreem

July 20, 2011 424B3

PROSPECTUS 59,687,333 Shares Common Stock, par value $0.01

Filed pursuant to Rule 424(b)(3) Registration Statement No. 333-171140 PROSPECTUS 59,687,333 Shares Common Stock, par value $0.01 This prospectus relates to the offer and sale from time to time of up to 29,075,000 shares of our outstanding common stock and 30,612,333 shares of our common stock issuable upon the exercise of warrants previously issued to certain shareholders named in this prospectus

July 15, 2011 POS AM

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Post-Effective Amendment No. 5 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 INTERNATIONAL ISOTOPES INC. (Exact name of registrant as specified in its charter)

As filed with the Securities and Exchange Commission on July 15, 2011 Registration No.

July 14, 2011 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 July 12, 2011 Date of Report (Date of earliest event reported) INTERNATIONAL ISOTO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 July 12, 2011 Date of Report (Date of earliest event reported) INTERNATIONAL ISOTOPES INC. (Exact name of registrant as specified in charter) Texas 0-22923 74-2763837 (State or other jurisdiction of incorporation) (Commission File N

July 7, 2011 POS AM

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Post-Effective Amendment No. 4 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 INTERNATIONAL ISOTOPES INC. (Exact name of registrant as specified in its charter)

As filed with the Securities and Exchange Commission on July 7, 2011 Registration No.

July 5, 2011 CORRESP

July 5, 2011

July 5, 2011 VIA EDGAR FILING AND FEDERAL EXPRESS Alicia Lam Geoffrey Kruczek U.S. Securities and Exchange Commission 100 F. Street, N.E. Washington, D.C. 20549 Re: International Isotopes Inc. Post-effective amendment No.3 to Form S-1 Filed June 10, 2011 File No. 333-171140 Dear Alicia and Geoffrey: Reference is made to (i) the comments of the Commission's staff (the ?Staff?) in regard to Internat

July 5, 2011 CORRESP

ANCHORAGE ž BEIJING ž BELLEVUE ž BOISE ž CHICAGO ž DALLAS ž DENVER ž LOS ANGELES ž MADISON ž NEW YORK PALO ALTO ž PHOENIX ž PORTLAND ž SAN DIEGO ž SAN FRANCISCO ž SEATTLE ž SHANGHAI ž WASHINGTON, D.C.

CORRESP 1 filename1.htm Sonny Allison PHONE: (303) 291-2314 FAX: (303) 291-2414 EMAIL: [email protected] July 5, 2011 VIA EDGAR FILING AND FEDERAL EXPRESS Alicia Lam Geoffrey Kruczek U.S. Securities and Exchange Commission 100 F. Street, N.E. Washington, D.C. 20549 Re: International Isotopes Inc. Post-effective Amendment No. 3 to Form S-1 Filed June 10, 2011 File No. 333-171140 Dear Alicia

June 10, 2011 POS AM

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Post-Effective Amendment No. 3 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 INTERNATIONAL ISOTOPES INC. (Exact name of registrant as specified in its charter)

INTERNATIONAL ISOTOPES INC. As filed with the Securities and Exchange Commission on June 10, 2011 Registration No. 333-171140 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Post-Effective Amendment No. 3 to FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 INTERNATIONAL ISOTOPES INC. (Exact name of registrant as specified in its charter) Texas 3823 74-276383

June 8, 2011 EX-99

EX-99

* * * * * * *

June 8, 2011 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant To Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 8, 2011 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) TEXAS 0-22923 74-2763837 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 31, 2011 CORRESP

May 31, 2011

International Isotopes Inc. May 31, 2011 VIA EDGAR FILING AND FEDERAL EXPRESS Alicia Lam Geoffrey Kruczek U.S. Securities and Exchange Commission 100 F. Street, N.E. Washington, D.C. 20549 Re: International Isotopes Inc. Form S-1 and Post-effective Amendment Nos. 1 and 2 to Form S-1 Filed December 13, 2010, April 15, 2010 and April 29, 2011 File No. 333-171140 Dear Alicia and Geoffrey: Reference i

May 31, 2011 CORRESP

[PERKINS COIE LLP LETTERHEAD]

International Isotopes Inc. [PERKINS COIE LLP LETTERHEAD] Sonny Allison PHONE: (303) 291-2314 FAX: (303) 291-2414 EMAIL: [email protected] May 31, 2011 VIA EDGAR FILING AND FEDERAL EXPRESS Alicia Lam Geoffrey Kruczek U.S. Securities and Exchange Commission 100 F. Street, N.E. Washington, D.C. 20549 Re: International Isotopes Inc. Form S-1 and Post-effective Amendment Nos. 1 and 2 to Form S-

May 18, 2011 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2011 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission f

May 17, 2011 NT 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING Commission File Number 000-22923 CUSIP Number 45972C102 (Check One): o Form 10-K o Form 20-F o Form 11-K x Form 10-Q o Form 10-D o Form N-SAR o Form N-CSR For period ended: March 31, 2011 o Transition Report on Form 10-K o Transition Report on Form 20-F o Transition Report on Form 11-K o

April 29, 2011 DEF 14A

SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

INTERNATIONAL ISOTOPES INC. SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) x Definitive Proxy Statement ¨ Definitive Additional Materials ¨ Sol

April 29, 2011 POS AM

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Post-Effective Amendment No. 2 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 INTERNATIONAL ISOTOPES INC. (Exact name of registrant as specified in its charter)

As filed with the Securities and Exchange Commission on April 29, 2011 Registration No.

April 15, 2011 POS AM

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Post-Effective Amendment No. 1 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 INTERNATIONAL ISOTOPES INC. (Exact name of registrant as specified in its charter)

INTERNATIONAL ISOTOPES INC. As filed with the Securities and Exchange Commission on April 14, 2011 Registration No. 333-171140 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Post-Effective Amendment No. 1 to FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 INTERNATIONAL ISOTOPES INC. (Exact name of registrant as specified in its charter) Texas 3823 74-27638

April 15, 2011 AW

INTERNATIONAL ISOTOPES INC. 4137 Commerce Circle Idaho Falls, Idaho 83401

INTERNATIONAL ISOTOPES INC. 4137 Commerce Circle Idaho Falls, Idaho 83401 April 14, 2011 Via EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street N.E. Washington, DC 20549-0404 Re: International Isotopes Inc. Request for Withdrawal of Amendment No. 1 to Registration Statement on Form S-1 (File No. 333-171140) Ladies and Gentlemen: On April 5, 2011, International Is

April 5, 2011 S-1/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Amendment No. 1 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 INTERNATIONAL ISOTOPES INC. (Exact name of registrant as specified in its charter)

As filed with the Securities and Exchange Commission on April 5, 2011 Registration No.

March 31, 2011 EX-4

INTERNATIONAL ISOTOPES INC. CLASS J WARRANT

Exhibit 4.7 NEITHER THESE SECURITIES NOR THE SECURITIES INTO WHICH THESE SECURITIES ARE EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE ?SECURITIES ACT?), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE

March 31, 2011 EX-10

MODIFICATION #1 TO THE AGREEMENNT

Exhibit 10.27 Exhibit 10.27 MODIFICATION #1 TO THE AGREEMENNT THIS MODIFICATION #1 is made to the Amended and Restated Employment Agreement entered into on June 23, 2010 by and between INTERNATIONAL ISOTOPES INC., a public corporation incorporated in the state of Texas (hereinafter “INIS”) and STEPHEN LAFLIN, (hereinafter “Mr. Laflin”). WITNESSETH: WHEREAS, The original agreement between the Parti

March 31, 2011 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2010 o TRANSITION REPORT PURSUANT TO SEC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2010 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 000-22923 INTERNATIONAL ISOTOPES I

March 31, 2011 EX-10

MODIFICATION #2 TO THE AGREEMENNT

Exhibit 10.28 Exhibit 10.28 MODIFICATION #2 TO THE AGREEMENNT THIS MODIFICATION #2 is made to the Amended and Restated Employment Agreement entered into on June 23, 2010 by and between INTERNATIONAL ISOTOPES INC., a public corporation incorporated in the state of Texas (hereinafter “INIS”) and STEPHEN LAFLIN, (hereinafter “Mr. Laflin”). WITNESSETH: WHEREAS, The original agreement between the Parti

March 18, 2011 RW

March 18, 2011

International Isotopes Inc. March 18, 2011 VIA EDGAR AND FAX U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, NE Washington, DC 20549 Re: Request for Withdrawal of Registration Statement on Form S-3 (File No. 333-167566) Ladies and Gentlemen: International Isotopes Inc. (the "Company") hereby requests, pursuant to Rule 477 of the Securities Act of 1933, as amen

February 25, 2011 424B2

SUBJECT TO COMPLETION, DATED FEBRUARY 25, 2011

Use these links to rapidly review the document Base Prospectus TABLE OF CONTENTS Table of Contents Filed Pursuant to Rule 424(b)(2) Registration Statement No.

February 14, 2011 SC 13G/A

UNITED STATES

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* INTERNATIONAL ISOTOPES, INC. (Name of Issuer) Common Stock, $.01 par value (Title of Class of Securities) 45972C102 (CUSIP Number) December 31, 2010 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule p

January 6, 2011 424B3

PROSPECTUS 59,687,333 Shares Common Stock, par value $0.01

Filed pursuant to Rule 424(b)(3) Registration Statement No. 333-171140 PROSPECTUS 59,687,333 Shares Common Stock, par value $0.01 This prospectus relates to the offer and sale from time to time of up to 29,075,000 shares of our outstanding common stock and 30,612,333 shares of our common stock issuable upon the exercise of warrants previously issued to certain shareholders named in this prospectus

December 13, 2010 S-1

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 INTERNATIONAL ISOTOPES INC. (Exact name of registrant as specified in its charter) Texas 3823 74-2763837 (State o

As filed with the Securities and Exchange Commission on December 13, 2010 Registration No.

November 5, 2010 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q

10-Q 1 f10q093010.htm 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2010 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commissio

November 2, 2010 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant To Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 2, 2010 INTERNATIONAL IS

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant To Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 2, 2010 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) TEXAS 0-22923 74-2763837 (State or Other Jurisdiction o

November 2, 2010 EX-99

EX-99

November 2, 2010 EX-1

JOINT FILING AGREEMENT

Exhibit 1 JOINT FILING AGREEMENT Firebird Global Master Fund II, Ltd., FG2 Advisors, LLC, James Passin, and Harvey Sawikin, in compliance with Rule 13d-1(k) of the Securities and Exchange Commission, hereby agree that the statement on Schedule 13D to which this Agreement is attached as an exhibit is, and any amendments thereto filed by any of us will be, filed on behalf of each such person or enti

November 2, 2010 SC 13D/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 6)* International Isotopes Inc. (Name of issuer) Common Stock, par value $0.01 per share (Title of class of

SC 13D/A 1 dsc13da.htm SCHEDULE 13D AMENDMENT NO. 6 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 6)* International Isotopes Inc. (Name of issuer) Common Stock, par value $0.01 per share (Title of class of securities) 45972C102 (CUSIP number) Joanne Tuckman Chief Financial Officer FG2 Advisors, LLC 152

November 1, 2010 EX-99

INTERNATIONAL ISOTOPES INC. ANNOUNCES COMPLETION OF A $5.8 MILLION PRIVATE PLACEMENT Funding Will Allow The Company To Continue Its Efforts On The Licensing And Design Of Planned Uranium De-Conversion And Fluorine Extraction Processing Facility

Exhibit 99.3 FOR IMMEDIATE RELEASE: November 1, 2010 INTERNATIONAL ISOTOPES INC. ANNOUNCES COMPLETION OF A $5.8 MILLION PRIVATE PLACEMENT Funding Will Allow The Company To Continue Its Efforts On The Licensing And Design Of Planned Uranium De-Conversion And Fluorine Extraction Processing Facility Idaho Falls, ID. November 1, 2010 ? International Isotopes Inc. (OTC Bulletin Board: INIS) announces c

November 1, 2010 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant To Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): October 29, 2010 INTERNATIONAL IS

INTERNATIONAL ISOTOPES INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant To Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): October 29, 2010 INTERNATIONAL ISOTOPES INC. (Exact Name of Registrant as Specified in Its Charter) TEXAS 0-22923 74-2763837 (State or Other Jurisdiction o

November 1, 2010 EX-99

SECURITIES PURCHASE AGREEMENT

Exhibit 99.1 Execution Copy SECURITIES PURCHASE AGREEMENT This SECURITIES PURCHASE AGREEMENT (this ?Agreement?), dated October 29, 2010, is between International Isotopes Inc., a Texas corporation (the ?Company?), and each purchaser identified on Schedule A hereto (each, including their respective successors and assigns, an ?Investor? and collectively, the ?Investors?) and, with respect to certain

November 1, 2010 EX-99

REGISTRATION RIGHTS AGREEMENT

Exhibit 99.2 Exhibit 99.2 Execution Copy REGISTRATION RIGHTS AGREEMENT This REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated October 29, 2010, is between International Isotopes Inc., a Texas corporation (the “Company”), and each purchaser identified on Schedule A hereto (each, including their respective successors and assigns, an “Investor” and collectively, the “Investors”). WHEREAS, in co

November 1, 2010 EX-4

INTERNATIONAL ISOTOPES INC. COMMON STOCK PURCHASE WARRANT

Exhibit 4.1 NEITHER THESE SECURITIES NOR THE SECURITIES INTO WHICH THESE SECURITIES ARE CONVERTIBLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "SECURITIES ACT"), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE

August 16, 2010 EX-10

EX-10

August 16, 2010 EX-3

Restated Certificate of Formation, as amended

Exhibit 3.1 CERTIFICATE OF AMENDMENT TO RESTATED CERTIFICATE OF FORMATION OF INTERNATIONAL ISOTOPES INC. International Isotopes Inc. (the "Corporation"), a corporation organized and existing under and by virtue of the Texas Business Organizations Code, hereby certifies that: 1. The name of the filing entity is International Isotopes Inc. 2. The filing entity is a For-profit Corporation. 3. The fir

August 16, 2010 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q

10-Q 1 f10q063010.htm 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2010 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission fil

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