OPHLY / Ono Pharmaceutical Co., Ltd. - Depositary Receipt (Common Stock) - Pengajuan SECLaporan Tahunan, Pernyataan Proksi

DMLRY / Daimler AG F-6EF - -

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT Under THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts Ono Pharmaceutical Co Ltd (Exact name of Issuer of deposited securities as specified in its charter) Japan (Jurisdiction of Incorporation or organization of Issuer) JPMorgan Chase Bank, N.A. (Exact name o

JPMorgan Chase Bank, N.A. American Depositary Receipt American Depositary Shares Representing Shares of Common Stock of Ono Pharmaceutical Co Ltd (Incorporated under the laws of Japan)

SUBSCRIPTION RIGHTS: Under current Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security.

Certification under Rule 466

Certification under Rule 466 The depositary, JPMorgan Chase Bank, N.A., represents and certifies the following: (1) That it previously had filed a registration statement on Form F-6 (Softbank Mobile Service Corp., 333-229175) that the Commission declared effective, with terms of deposit identical to the terms of deposit of this registration statement. (2) That its ability to designate the date and

Ziegler, Ziegler & Associates LLP Counselors at Law 570 Lexington Avenue, Suite 2405 New York, New York 10022 (212) 319-7600 Telecopier (212) 319-7605 October 15, 2019

Ziegler, Ziegler & Associates LLP Counselors at Law 570 Lexington Avenue, Suite 2405 New York, New York 10022 (212) 319-7600 Telecopier (212) 319-7605 October 15, 2019 JPMorgan Chase Bank, N.

THE RELEASE OF THE SHARES OF STOCK OF THE ISSUER (AS HEREINAFTER DEFINED) UNDERLYING THE ADSs REPRESENTED BY THIS ADR MAY BE LIMITED TO A UNIT OF SUCH NUMBER OF SHARES OF STOCK AS THE ARTICLES OF INCORPORATION MAY FROM TIME TO TIME DESIGNATE AS A "UN

SUBSCRIPTION RIGHTS: Under current Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security.

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 POST-EFFECTIVE AMENDMENT TO FORM F-6 REGISTRATION STATEMENT THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts Ono Pharmaceutical Co., Ltd. (Ex

333-153926 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 POST-EFFECTIVE AMENDMENT TO FORM F-6 REGISTRATION STATEMENT Under THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts Ono Pharmaceutical Co., Ltd. (Exact name of Issuer of deposited securities as specified in its charter) Japan (Jurisdiction of Incorporation or organization of Issue

Certification under Rule 466

Certification under Rule 466 The depositary, Deutsche Bank Trust Company Americas, represents and certifies the following: (1) That it previously had filed a registration statement on Form F-6 (Uniper SE, 333-217999) that the Commission declared effective, with terms of deposit identical to the terms of deposit of this registration statement.

THE RELEASE OF THE SHARES OF STOCK OF THE ISSUER (AS HEREINAFTER DEFINED) UNDERLYING THE ADSs REPRESENTED BY THIS ADR MAY BE LIMITED TO A UNIT OF SUCH NUMBER OF SHARES OF STOCK AS THE ARTICLES OF INCORPORATION MAY FROM TIME TO TIME DESIGNATE AS A "UN

SUBSCRIPTION RIGHTS: Under current Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Post-effective Amendment No. 1 FORM F-6 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 FOR AMERICAN DEPOSITARY SHARES EVIDENCED BY AMERICAN DEPOSITARY RECEIPTS Ono Pharm

As filed with the Securities and Exchange Commission on May 22, 2017 Registration No.

Each American Depositary Share represents one third of one Share Deutsche Bank Trust Company Americas American Depositary Receipt American Depositary Shares representing common stock of Ono Pharmaceutical Co Ltd (Incorporated under the laws of Japan)

Number Each American Depositary Share represents one third of one Share Deutsche Bank Trust Company Americas American Depositary Receipt Evidencing American Depositary Shares representing common stock of Ono Pharmaceutical Co Ltd (Incorporated under the laws of Japan) Deutsche Bank Trust Company Americas, as Depositary (hereinafter referred to as the Depositary), hereby certifies that (i) at the d

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Pre-effective Amendment No. 1 FORM F-6 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 FOR AMERICAN DEPOSITARY SHARES EVIDENCED BY AMERICAN DEPOSITARY RECEIPTS Ono Pharma

As filed with the Securities and Exchange Commission on April 25, 2017 Registration No.

Ono Pharmaceutical FORM F-6

a16-14f6.htm As filed with the Securities and Exchange Commission on October 17, 2016 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 FOR AMERICAN DEPOSITARY SHARES EVIDENCED BY AMERICAN DEPOSITARY RECEIPTS Ono Pharmaceutical Co Ltd (Exact name of issuer of deposited securities as specifi

Each American Depositary Share represents one third of one Share Deutsche Bank Trust Company Americas American Depositary Receipt American Depositary Shares representing common stock of Ono Pharmaceutical Co Ltd (Incorporated under the laws of Japan)

a16-14ex4.htm Number Each American Depositary Share represents one third of one Share Deutsche Bank Trust Company Americas American Depositary Receipt Evidencing American Depositary Shares representing common stock of Ono Pharmaceutical Co Ltd (Incorporated under the laws of Japan) Deutsche Bank Trust Company Americas, as Depositary (hereinafter referred to as the Depositary), hereby certifies tha

Ono Pharmaceutical F

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT Under THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts Ono Pharmaceutical Co Ltd (Exact name of Issuer of deposited securities as specified in its charter) Japan (Jurisdiction of Incorporation or organization of Issuer) JPMorgan Chase Bank, N.A. (Exact name o

THE RELEASE OF THE SHARES OF STOCK OF THE ISSUER (AS HEREINAFTER DEFINED) UNDERLYING THE ADSs REPRESENTED BY THIS ADR MAY BE LIMITED TO A UNIT OF SUCH NUMBER OF SHARES OF STOCK AS THE ARTICLES OF INCORPORATION MAY FROM TIME TO TIME DESIGNATE AS A "UN

Unassociated Document SUBSCRIPTION RIGHTS: Under current Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security.

Certification under Rule 466

Unassociated Document Certification under Rule 466 The depositary, JPMorgan Chase Bank, N.

Ono Pharmaceutical F

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT Under THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts Ono Pharmaceutical Co Ltd (Exact name of Issuer of deposited securities as specified in its charter) Japan (Jurisdiction of Incorporation or organization of Issuer) JPMorgan Chase Bank, N.A. (Exact name o

THE RELEASE OF THE SHARES OF STOCK OF THE ISSUER (AS HEREINAFTER DEFINED) UNDERLYING THE ADSs REPRESENTED BY THIS ADR MAY BE LIMITED TO A UNIT OF SUCH NUMBER OF SHARES OF STOCK AS THE ARTICLES OF INCORPORATION MAY FROM TIME TO TIME DESIGNATE AS A "UN

Unassociated Document SUBSCRIPTION RIGHTS: Under current Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security.

Ziegler, Ziegler & Associates LLP Counselors at Law 570 Lexington Avenue, Suite 2405 New York, New York 10022 (212) 319-7600 Telecopier (212) 319-7605 August 25, 2016 JPMorgan Chase Bank, N.A., as Depositary

Unassociated Document Ziegler, Ziegler & Associates LLP Counselors at Law 570 Lexington Avenue, Suite 2405 New York, New York 10022 (212) 319-7600 Telecopier (212) 319-7605 August 25, 2016 JPMorgan Chase Bank, N.

Ziegler, Ziegler & Associates LLP Counselors at Law 570 Lexington Avenue, Suite 2405 New York, New York 10022 (212) 319-7600 Telecopier (212) 319-7605 August 25, 2016 JPMorgan Chase Bank, N.A., as Depositary

Unassociated Document Ziegler, Ziegler & Associates LLP Counselors at Law 570 Lexington Avenue, Suite 2405 New York, New York 10022 (212) 319-7600 Telecopier (212) 319-7605 August 25, 2016 JPMorgan Chase Bank, N.

Certification under Rule 466

Unassociated Document Certification under Rule 466 The depositary, JPMorgan Chase Bank, N.

As filed with the Securities and Exchange Commission on May 24, 2016

As filed with the Securities and Exchange Commission on May 24, 2016 Registration No.

THE BANK OF NEW YORK MELLON FORM OF AMERICAN DEPOSITARY RECEIPT STATEMENT OF TERMS AND CONDITIONS WITH RESPECT TO AMERICAN DEPOSITARY SHARES SHARES OF COMMON STOCK, OF ONO PHARMACEUTICAL CO., LTD (THE “COMPANY”) (INCORPORATED UNDER THE LAWS OF JAPAN)

AMERICAN DEPOSITARY SHARES (One (1) American Depositary Share represents One-third (1/3) of one Share) THE BANK OF NEW YORK MELLON FORM OF AMERICAN DEPOSITARY RECEIPT AND STATEMENT OF TERMS AND CONDITIONS WITH RESPECT TO AMERICAN DEPOSITARY SHARES REPRESENTING SHARES OF COMMON STOCK, OF ONO PHARMACEUTICAL CO.

Ono Pharmaceutical POS

Unassociated Document As filed with the Securities and Exchange Commission on March 30, 2016 Registration No.

Rule 466 Certification

Unassociated Document Exhibit (e) Rule 466 Certification The depositary, Citibank, N.

AMERICAN DEPOSITARY SHARES

Unassociated Document Exhibit (a) NUMBER AMERICAN DEPOSITARY SHARES CUSIP # Each American Depositary Share represents one-third (1/3) of one share of common stock of the Company SUBSCRIPTION RIGHTS: Under Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security.

As filed with the Securities and Exchange Commission on July 24, 2015 Registration No. 333-_____

As filed with the Securities and Exchange Commission on July 24, 2015 Registration No.

LETTERHEAD OF PATTERSON BELKNAP WEBB & TYLER LLP

Exhibit (d) LETTERHEAD OF PATTERSON BELKNAP WEBB & TYLER LLP July 24, 2015 Citibank, N.

Rule 466 Certification

Exhibit (e) Rule 466 Certification The depositary, Citibank, N.A., represents and certifies the following: 1. That it previously had filed a registration statement on Form F-6 (Registration No. 333-202848), which the U.S. Securities and Exchange Commission declared effective, with terms of deposit identical to the terms of deposit of this Form F-6 Registration Statement (except for the name of the

AMERICAN DEPOSITARY SHARES

Exhibit (a) NUMBER AMERICAN DEPOSITARY SHARES CUSIP # Each American Depositary Share represents one-fifth (1/5) of one share of common stock of the Company SUBSCRIPTION RIGHTS: Under Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security.

THE BANK OF NEW YORK MELLON AMERICAN DEPOSITARY RECEIPT FOR COMMON STOCK, ONO PHARMACEUTICAL CO., LTD. (INCORPORATED UNDER THE LAWS OF JAPAN)

AMERICAN DEPOSITARY SHARES (One (1) American Depositary Share represents One-Fifth (1/5) of one Share) THE BANK OF NEW YORK MELLON AMERICAN DEPOSITARY RECEIPT FOR COMMON STOCK, OF ONO PHARMACEUTICAL CO.

- POST EFFECTIVE AMENDMENT NO.1 TO THE FORM F-6

As filed with the Securities and Exchange Commission on May 23, 2014 Registration No.

As filed with the Securities and Exchange Commission on October 31, 2008 Registration No. 333- SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT THE SECURITIES ACT OF 1933 For Depositary Shares Evidenced by Ame

F-6EF 1 onounsponsoredformf6.htm FORM F-6 As filed with the Securities and Exchange Commission on October 31, 2008 Registration No. 333- SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT under THE SECURITIES ACT OF 1933 For Depositary Shares Evidenced by American Depositary Receipts of ONO PHARMACEUTICAL CO., LTD. (Exact name of issuer of deposited securitie

THE BANK OF NEW YORK MELLON AMERICAN DEPOSITARY RECEIPT FOR COMMON STOCK, NO PAR VALUE, OF ONO PHARMACEUTICAL CO., LTD. (INCORPORATED UNDER THE LAWS OF JAPAN)

AMERICAN DEPOSITARY SHARES (One (1) American Depositary Share represents One (1) Share) THE BANK OF NEW YORK MELLON AMERICAN DEPOSITARY RECEIPT FOR COMMON STOCK, NO PAR VALUE, OF ONO PHARMACEUTICAL CO.

EMMET, MARVIN & MARTIN, LLP COUNSELLORS AT LAW 120 Broadway New York, New York 10271 (212) 238-3000 (212) 653-1760 Fax: (212) 238-3100 Fax: (212) 653-1730

EXHIBIT 4 Writer?s Direct Dial EMMET, MARVIN & MARTIN, LLP COUNSELLORS AT LAW 120 Broadway New York, New York 10271 (212) 238-3000 (212) 653-1760 Fax: (212) 238-3100 Fax: (212) 653-1730 http://www.

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts Ono Pharmaceutical Co., Ltd. (Exact name of Issuer of deposi

F-6EF 1 a08-24918113f6ef.htm F-6EF SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT Under THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts Ono Pharmaceutical Co., Ltd. (Exact name of Issuer of deposited securities as specified in its charter) Japan (Jurisdiction of Incorporation or organization of Issuer) D

Ziegler, Ziegler & Associates LLP Counselors at Law 570 Lexington Avenue, 44th Floor New York, New York 10022 (212) 319-7600 Telecopier (212) 319-7605 October 6, 2008

Exhibit 99(d) Ziegler, Ziegler & Associates LLP Counselors at Law 570 Lexington Avenue, 44th Floor New York, New York 10022 (212) 319-7600 Telecopier (212) 319-7605 October 6, 2008 Deutsche Bank Trust Company Americas, as Depositary 60 Wall Street New York, New York 10005 American Depositary Shares evidenced by American Depositary Receipts for deposited shares of the foreign private issuer whose n

Number

Exhibit 99(a) SUBSCRIPTION RIGHTS: Under current Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security.

Certification under Rule 466

Exhibit 99(e) Certification under Rule 466 The depositary, Deutsche Bank Trust Company Americas, represents and certifies the following: (1) That it previously had filed a registration statement on Form F-6 (Premier Farnell plc 333-153746) that the Commission declared effective, with terms of deposit identical to the terms of deposit of this registration statement.