PKTX / ProtoKinetix, Incorporated - Pengajuan SECLaporan Tahunan, Pernyataan Proksi

ProtoKinetix, Incorporated
US ˙ OTCPK

Mga Batayang Estadistika
CIK 1128189
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to ProtoKinetix, Incorporated
SEC Filings (Chronological Order)
Halaman ini menyediakan daftar lengkap dan kronologis dari Pengajuan SEC, tidak termasuk pengajuan kepemilikan yang kami sediakan di tempat lain.
September 5, 2025 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A CONSENT SOLICITATION PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A CONSENT SOLICITATION PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. ) Check the appropriate box: [X] Preliminary Proxy Statement [ ] Confidential, for use of the Commission only as permitted by Rule 14a-6(e)(2) [ ] Definitive Proxy Statement [ ] Definitive Additional Material [ ] S

August 13, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 ☐ TRANSITION REPORT UNDER SECTIO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 000-32917 PROTOKINETIX, INCORPORAT

May 15, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 ☐ TRANSITION REPORT UNDER SECTI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 000-32917 PROTOKINETIX, INCORPORA

May 15, 2025 EX-4.5

Form of Warrant

EXHIBIT 4.5 WARRANT AGREEMENT Neither THE WARRANT, NOR THE SHARES UNDERLYING THE WARRANT, GRANTED HEREUNDER TO WHICH THIS WARRANT AGREEMENT RELATES HAVE BEEN REGISTERED UNDER THE securities act of 1933, as amended (the “1933 Act”) AND, UNLESS SO REGISTERED, NONE MAY BE OFFERED OR SOLD, DIRECTLY OR INDIRECTLY EXCEPT IN ACCORDANCE WITH THE PROVISIONS OF REGULATION S UNDER THE 1933 ACT, PURSUANT TO A

March 28, 2025 EX-19.1

Insider Trading Policy adopted July 8, 2019

Exhibit 19.1 protokinetix, Incorporated INSIDER TRADING POLICY Adopted by the Board of Directors on July 8, 2019 PURPOSES This Insider Trading Policy is being adopted in order to assure compliance with the laws prohibiting “insider trading” in Company Securities, including Derivative Securities, and to avoid the appearance of impropriety and resulting damage to the Company’s reputation for integri

March 28, 2025 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INCORPORATED (Name of

March 28, 2025 EX-19.2

Policy on Trading Blackout Periods adopted July 8, 2019

Exhibit 19.2 protokinetix, Incorporated POLICY ON TRADING BLACKOUT PERIODS; BENEFIT PLANS; AND SECTION 16 REPORTING This Policy was unanimously adopted by the Board of Directors of ProtoKinetix, Incorporated on July 8, 2019. It applies to the directors, certain executive officers and certain accounting personnel and consultants of the Company. ProtoKinetix, Incorporated (the “Company”) has adopted

March 28, 2025 EX-4.6

Description of Capital Stock of the Company

EXHIBIT 4.6 DESCRIPTION OF OUR SECURITIES The following description summarizes important terms of our capital stock and our other securities. For a complete description, you should refer to our Articles of Incorporation and bylaws, forms of which are incorporated by reference to the exhibits to the annual report of which this is a part, as well as the relevant portions of the Nevada Revised Statut

November 12, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 ☐ TRANSITION REPORT UNDER S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 000-32917 PROTOKINETIX, INCOR

July 30, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 ☐ TRANSITION REPORT UNDER SECTIO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 000-32917 PROTOKINETIX, INCORPORAT

June 17, 2024 SC 13D/A

PKTX / ProtoKinetix, Incorporated / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A Under the Securities Exchange Act of 1934 (Amendment No. 21)* PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1409 Peachtree Road Dayton Beach, Florida 32114 (304) 299-5070 (Name, Address and Teleph

May 15, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 ☐ TRANSITION REPORT UNDER SECTI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 000-32917 PROTOKINETIX, INCORPORA

March 20, 2024 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INCORPORATED (Name of

March 20, 2024 EX-4.6

Description of Capital Stock of the Company*

Exhibit 4.6 DESCRIPTION OF OUR SECURITIES The following description summarizes important terms of our capital stock and our other securities. For a complete description, you should refer to our Articles of Incorporation and bylaws, forms of which are incorporated by reference to the exhibits to the annual report of which this is a part, as well as the relevant portions of the Nevada Revised Statut

December 28, 2023 SC 13D/A

PKTX / ProtoKinetix, Incorporated / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

SC 13D/A 1 pktxsmith13da20.htm SCHEDULE 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A Under the Securities Exchange Act of 1934 (Amendment No. 20)* PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1409 Peachtree Road Dayton Beach, Florida

October 18, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 ☐ TRANSITION REPORT UNDER S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 000-32917 PROTOKINETIX, INCOR

July 14, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 ☐ TRANSITION REPORT UNDER SECTIO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 000-32917 PROTOKINETIX, INCORPORAT

June 15, 2023 SC 13D/A

PKTX / Protokinetix, Inc. / SMITH CLARENCE EDWARD Activist Investment

Schedule 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A Under the Securities Exchange Act of 1934 (Amendment No. 19)* PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1409 Peachtree Road Dayton Beach, Florida 32114 (304) 299-5070 (Name, Addre

May 2, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 ☐ TRANSITION REPORT UNDER SECTI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 000-32917 PROTOKINETIX, INCORPORA

March 17, 2023 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INCORPORATED (Name of

March 17, 2023 EX-4.6

Description of our Securities*

Exhibit 4.6 DESCRIPTION OF OUR SECURITIES The following description summarizes important terms of our capital stock and our other securities. For a complete description, you should refer to our Articles of Incorporation and bylaws, forms of which are incorporated by reference to the exhibits to the annual report of which this is a part, as well as the relevant portions of the Nevada Revised Statut

March 17, 2023 EX-4.5

Form of Warrant(13)

Exhibit 4.5 WARRANT AGREEMENT Neither THE WARRANT, NOR THE SHARES UNDERLYING THE WARRANT, GRANTED HEREUNDER TO WHICH THIS WARRANT AGREEMENT RELATES HAVE BEEN REGISTERED UNDER THE securities act of 1933, as amended (the “1933 Act”) AND, UNLESS SO REGISTERED, NONE MAY BE OFFERED OR SOLD, DIRECTLY OR INDIRECTLY EXCEPT IN ACCORDANCE WITH THE PROVISIONS OF REGULATION S UNDER THE 1933 ACT, PURSUANT TO A

March 17, 2023 EX-4.4

Consultant Warrant

Exhibit 4.4 WARRANT AGREEMENT Neither THE WARRANT, NOR THE SHARES UNDERLYING THE WARRANT, GRANTED HEREUNDER TO WHICH THIS WARRANT AGREEMENT RELATES HAVE BEEN REGISTERED UNDER THE securities act of 1933, as amended (the “1933 Act”) OR ANY U.S. STATE SECURITIES LAWS, AND, UNLESS SO REGISTERED, NONE MAY BE OFFERED OR SOLD, DIRECTLY OR INDIRECTLY, IN THE UNITED STATES OR TO U.S. PERSONS (AS DEFINED HE

February 15, 2023 SC 13G/A

PKTX / ProtoKinetix, Inc. / Young Lachlan Grant - SCHEDULE 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 8)* ProtoKinetix, Incorporated (Name of Issuer) Common Stock, $0.0000053 par value per share (Title of Class Securities) 743722100 (CUSIP NUMBER) December 31, 2022 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designa

February 15, 2023 SC 13G/A

PKTX / ProtoKinetix, Inc. / Smith Alexandra Blake - SCHEDULE 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 2) ProtoKinetix, Incorporated (Name of Issuer) Common Stock, $0.0000053 par value per share (Title of Class Securities) 743722100 (CUSIP NUMBER) December 31, 2022 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designat

February 15, 2023 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

SC 13D/A 1 pktxsmith13da18.htm SCHEDULE 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A Under the Securities Exchange Act of 1934 (Amendment No. 18)* PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1409 Peachtree Road Dayton Beach, Florida

February 1, 2023 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: January 23, 2023 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Commission IRS Employer Incorporation File Number Identification No. 109 W. Main

January 4, 2023 8-K

Unregistered Sales of Equity Securities, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: December 30, 2022 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Commission IRS Employer Incorporation File Number Identification No. 109 W. Main

December 13, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Unregistered Sales of Equity Securities, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: December 7, 2022 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Commission IRS Employer Incorporation File Number Identification No. 412 Mulberry

October 31, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 ☐ TRANSITION REPORT UNDER S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 000-32917 PROTOKINETIX, INCOR

July 29, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 ☐ TRANSITION REPORT UNDER SECTIO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 OR ? TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 000-32917 PROTOKINETIX, INCORPORAT

May 10, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022 ☐ TRANSITION REPORT UNDER SECTI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022 OR ? TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 000-32917 PROTOKINETIX, INCORPORA

March 21, 2022 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

Schedule 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A Under the Securities Exchange Act of 1934 (Amendment No. 17)* PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1409 Peachtree Road Dayton Beac, Florida 32114 (304) 299-5070 (Name, Addres

March 21, 2022 EX-4

Amendment to Amended 2017 Stock Option and Stock Bonus Plan as approved on March 15, 2022(12)

Exhibit 4.1 AMENDMENT TO ProtoKinetix, Incorporated Amended 2017 Stock Option and Stock Bonus PLAN Section 5(a) of the Plan is hereby amended as follows: Section 5. Stock Reserved. (a) The stock subject to Awards hereunder shall be shares of Common Stock. Such shares, in whole or in part, may be authorized but unissued shares or shares that shall have been or that may be reacquired by the Corporat

March 21, 2022 SC 13G/A

PKTX / ProtoKinetix, Inc. / Young Lachlan Grant - SCHEDULE 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 7)* ProtoKinetix, Incorporated (Name of Issuer) Common Stock, $0.0000053 par value per share (Title of Class Securities) 743722100 (CUSIP NUMBER) December 31, 2021 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designa

March 21, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Unregistered Sales of Equity Securities, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: March 15, 2022 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Commission IRS Employer Incorporation File Number Identification No. 412 Mulberry S

March 21, 2022 SC 13G/A

PKTX / ProtoKinetix, Inc. / Smith Alexandra Blake - SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1) ProtoKinetix, Incorporated (Name of Issuer) Common Stock, $0.0000053 par value per share (Title of Class Securities) 743722100 (CUSIP NUMBER) December 31, 2021 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designat

March 10, 2022 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INCORPORATED (Name of

February 14, 2022 8-K

Regulation FD Disclosure, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Material Modification to Rights of Security Holders, Financial Statements and Exhibits, Other Events, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: February 11, 2022 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Commission IRS Employer Incorporation File Number Identification No. 412 Mulberr

February 14, 2022 EX-3.1

Amended and Restated Articles of Incorporation as filed on February 16, 2022(1)

Exhibit 4.1 Amended and Restated Articles of Incorporation of ProtoKinetix, Incorporated (the ?Corporation?) Pursuant to the provisions of Nevada Revised Statutes 78.390 and 78.403, the undersigned officer of ProtoKinetix, Incorporated, a Nevada corporation, formerly known as RJV Network, Inc., does hereby certify as follows: A. The Board of Directors of the Corporation has duly adopted resolution

February 11, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for use of the Commission only as permitted by Rule 14a-6(e)(2) [ ] Definitive Proxy Statement [X] Definitive Additional Material [ ] Solicitation Material u

January 14, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for use of the Commission only as permitted by Rule 14a-6(e)(2) [ ] Definitive Proxy Statement [X] Definitive Additional Material [ ] Solicitation Material u

December 30, 2021 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for use of the Commission only as permitted by Rule 14a-6(e)(2) [ ] Definitive Proxy Statement [X] Definitive Additional Material [ ] Solicitation Material u

December 30, 2021 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for use of the Commission only as permitted by Rule 14a-6(e)(2) [X] Definitive Proxy Statement [ ] Definitive Additional Material [ ] Solicitation Material u

December 23, 2021 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Material Modification to Rights of Security Holders, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: December 20, 2021 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Commission IRS Employer Incorporation File Number Identification No. 412 Mulberr

December 23, 2021 EX-3.1

Amended and Restated Bylaws of the Company as approved on December 20, 2021(2)

Exhibit 3.1 AMENDED AND RESTATED BYLAWS OF PROTOKINETIX, INCORPORATED ARTICLE I: OFFICES Section 1.1. Registered Agent and Office. The registered agent of ProtoKinetix, Incorporated (the ?Corporation?) shall be as set forth in the Corporation?s articles of incorporation, as amended or restated (the ?Articles of Incorporation?) and the registered office of the Corporation shall be the street office

December 20, 2021 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Check the appropriate box: [X] Preliminary Proxy Statement [ ] Confidential, for use of the Commission only as permitted by Rule 14a-6(e)(2) [ ] Definitive Proxy Statement [ ] Definitive Additional Material [ ] Solicitation Material u

November 12, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 ☐ TRANSITION REPORT UNDER S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 OR ? TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 000-32917 PROTOKINETIX, INCOR

August 6, 2021 SC 13G/A

PKTX / ProtoKinetix, Inc. / Young Lachlan Grant - SCHEDULE 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 6)* ProtoKinetix, Incorporated (Name of Issuer) Common Stock, $0.0000053 par value per share (Title of Class Securities) 743722100 (CUSIP NUMBER) August 4, 2021 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate

August 6, 2021 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A Under the Securities Exchange Act of 1934 (Amendment No. 16)* PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1845 County Road #214 St. Augustine, Florida 32084 (304) 299-5070 (Name, Address and Tel

August 6, 2021 SC 13G/A

PKTX / ProtoKinetix, Inc. / Young Lachlan Grant - SCHEDULE 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 5)* ProtoKinetix, Incorporated (Name of Issuer) Common Stock, $0.0000053 par value per share (Title of Class Securities) 743722100 (CUSIP NUMBER) December 31, 2020 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designa

July 28, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021 ☐ TRANSITION REPORT UNDER SECTIO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021 OR ? TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 000-32917 PROTOKINETIX, INCORPORAT

April 16, 2021 10-Q

Quarterly Report - FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2021 OR ? TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 000-32917 PROTOKINETIX, INCORPORA

March 5, 2021 10-K

Annual Report - FORM 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2020 [] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INCORPORATED (Name

October 16, 2020 10-Q

Quarterly Report - FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2020 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 000-32917 PROTOKINETIX, INCOR

August 13, 2020 SC 13G

PKTX / ProtoKinetix, Inc. / Smith Alexandra Blake - SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. ) ProtoKinetix, Incorporated (Name of Issuer) Common Stock, $0.0000053 par value per share (Title of Class Securities) 743722100 (CUSIP NUMBER) August 4, 2020 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the

August 10, 2020 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

Schedule 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A Under the Securities Exchange Act of 1934 (Amendment No. 15)* PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1845 County Road #214 St. Augustine, Florida 32084 (304) 299-5070 (Name, Ad

July 10, 2020 EX-3.5

Certificate of Change to the Articles of Incorporation as filed May 1, 2014(11)

Exhibit 3.5

July 10, 2020 10-Q

Quarterly Report - FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2020 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 000-32917 PROTOKINETIX, INCORPORAT

July 10, 2020 EX-3.2

Articles of Amendment to Articles of Incorporation as filed on July 8, 2003(11)

Exhibit 3.2

July 10, 2020 EX-3.3

Articles of Amendment to Articles of Incorporation as filed on December 8, 2003(11)

Exhibit 3.3

July 10, 2020 EX-3.4

Certificate of Change to the Articles of Incorporation as filed November 16, 2011(11)

Exhibit 3.4

June 18, 2020 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: June 12, 2020 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Commission IRS Employer Incorporation File Number Identification No. 412 Mulberry St

April 27, 2020 10-Q

Quarterly Report - FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2020 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 000-32917 PROTOKINETIX, INCORPORA

April 10, 2020 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: March 26, 2020 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Commission IRS Employer Incorporation File Number Identification No. 412 Mulberry S

April 10, 2020 EX-4.1

Amendment to Amended 2017 Stock Option and Stock Bonus Plan as approved on April 6, 2020(10)

Exhibit 4.1 AMENDMENT TO ProtoKinetix, Incorporated Amended 2017 Stock Option and Stock Bonus PLAN Section 5(a) of the Plan is hereby amended as follows: Section 5. Stock Reserved. (a) The stock subject to Awards hereunder shall be shares of Common Stock. Such shares, in whole or in part, may be authorized but unissued shares or shares that shall have been or that may be reacquired by the Corporat

April 1, 2020 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD Activist Investment

Schedule 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A Under the Securities Exchange Act of 1934 (Amendment No. 14)* PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1845 County Road #214 St. Augustine, Florida 32084 (304) 299-5070 (Name, Ad

March 31, 2020 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: March 25, 2020 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Commission IRS Employer Incorporation File Number Identification No. 412 Mulberry S

March 31, 2020 SC 13G/A

PKTX / ProtoKinetix, Inc. / Young Lachlan Grant - SCHEDULE 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 4)* ProtoKinetix, Incorporated (Name of Issuer) Common Stock, $0.0000053 par value per share (Title of Class Securities) 743722100 (CUSIP NUMBER) December 31, 2019 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designa

February 19, 2020 10-K

PKTX / ProtoKinetix, Inc. 10-K - Annual Report - FORM 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2019 [] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INCORPORATED (Name

October 26, 2019 10-Q

PKTX / ProtoKinetix, Inc. 10-Q - Quarterly Report - FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2019 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission file number: 000-32917 PROTOKINETIX, INCOR

July 26, 2019 10-Q

PKTX / ProtoKinetix, Inc. 10-Q - Quarterly Report - FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2019 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission file number: PROTOKINETIX, INCORPORATED (Exact

July 17, 2019 EX-14.1

Code of Business Conduct and Ethics and Whistleblower Policy as approved on July 8, 2019(5)

Exhibit 14.1 protokinetix, Incorporated CODE OF BUSINESS CONDUCT AND ETHICS AND WHISTLEBLOWER POLICY Adopted by the Board of Directors on July 8, 2019 Introduction ProtoKinetix, Incorporated (the “Company”) is committed to the highest standards of legal and ethical business conduct. This Code of Business Conduct and Ethics and Whistleblower Policy (the “Code”) summarizes the legal, ethical and reg

July 17, 2019 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Amendment to Registrant's Code of Ethics, or Waiver of a Provision of the Code of Ethics, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: July 8, 2019 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Commission IRS Employer Incorporation File Number Identification No. 412 Mulberry Str

July 17, 2019 EX-4.1

Amendment to Amended 2017 Stock Option and Stock Bonus Plan as approved on July 15, 2019(6)

Exhibit 4.1 AMENDMENT TO ProtoKinetix, Incorporated Amended 2017 Stock Option and Stock Bonus PLAN Section 5(a) of the Plan is hereby amended as follows: Section 5. Stock Reserved. (a) The stock subject to Awards hereunder shall be shares of Common Stock. Such shares, in whole or in part, may be authorized but unissued shares or shares that shall have been or that may be reacquired by the Corporat

July 17, 2019 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

Schedule 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A Under the Securities Exchange Act of 1934 (Amendment No. 13)* PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1845 County Road #214 St. Augustine, Florida 32084 (304) 299-5070 (Name, Ad

May 7, 2019 10-Q

PKTX / ProtoKinetix, Inc. 10-Q Quarterly Report FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2019 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission file number: PROTOKINETIX, INCORPORATED (Exact

April 16, 2019 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A (Amendment No. 12)* Under the Securities Exchange Act of 1934 PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1845 County Road #214 St. Augustine, Florida 32084 304-299-5070 (Name, Address and Telep

March 12, 2019 10-K

PKTX / ProtoKinetix, Inc. FORM 10-K (Annual Report)

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2018 [] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INCORPORATED (Name

February 20, 2019 SC 13G/A

PKTX / ProtoKinetix, Inc. / Young Lachlan Grant - SCHEDULE 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* ProtoKinetix, Incorporated (Name of Issuer) Common Stock, $0.0000053 par value per share (Title of Class Securities) 743722100 (CUSIP NUMBER) December 31, 2018 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate

January 2, 2019 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A (Amendment No. 11)* Under the Securities Exchange Act of 1934 PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1845 County Road #214 St. Augustine, Florida 32084 304-299-5070 (Name, Address and Telep

November 13, 2018 EX-4.1

Amended 2017 Stock Option and Stock Bonus Plan(3)

Exhibit 4.1 PROTOKINETIX, INCORPORATED AMENDED 2017 STOCK OPTION AND STOCK BONUS PLAN 1. Purposes of and Benefits Under the Plan. This Amended 2017 Stock Option and Stock Bonus Plan (the “Plan”) is intended to encourage stock ownership by employees, consultants, officers and directors of ProtoKinetix, Incorporated and its controlled, affiliated and subsidiary entities (collectively, the “Corporati

November 13, 2018 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: November 9, 2018 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 412 Mulberry

October 26, 2018 10-Q

PKTX / ProtoKinetix, Inc. FORM 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2018 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission file number: PROTOKINETIX, INCORPORATED (E

July 24, 2018 10-Q

PKTX / ProtoKinetix, Inc. FORM 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2018 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission file number: PROTOKINETIX, INCORPORATED (Exact

June 12, 2018 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A (Amendment No. 10)* Under the Securities Exchange Act of 1934 PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1845 County Road #214 St. Augustine, Florida 32084 304-299-5070 (Name, Address and Telep

April 26, 2018 10-Q

PKTX / ProtoKinetix, Inc. FORM 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2018 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission file number: PROTOKINETIX, INCORPORATED (Exact

March 9, 2018 10-K

PKTX / ProtoKinetix, Inc. FORM 10-K (Annual Report)

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2017 [] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INCORPORATED (Name

January 22, 2018 SC 13G/A

PKTX / ProtoKinetix, Inc. / Young Lachlan Grant - SCHEDULE 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* ProtoKinetix, Incorporated (Name of Issuer) Common Stock, $0.0000053 par value per share (Title of Class Securities) 743722100 (CUSIP NUMBER) December 31, 2017 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate

January 17, 2018 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A (Amendment No. 9)* Under the Securities Exchange Act of 1934 PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1845 County Road #214 St. Augustine, Florida 32084 304-299-5070 (Name, Address and Teleph

January 16, 2018 8-K

Termination of a Material Definitive Agreement, Unregistered Sales of Equity Securities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: January 12, 2018 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 412 Mulberry

November 14, 2017 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: November 14, 2017 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Ide ntification No. 412 Mulber

November 14, 2017 EX-10.1

Consulting Agreement between ProtoKinetix Incorporated and Michael Guzzetta, dated November 14, 2017(11)

Exhibit 10.1 PROTOKINETIX, INCORPORATED CONSULTING AGREEMENT This CONSULTING AGREEMENT (the ?Agreement?) is made and entered into as of November 14, 2017 (the ?Effective Date?), by and between ProtoKinetix, Incorporated, a Nevada corporation (?Company?), and Michael R. Guzzetta, CPA, an individual (?Consultant?). WHEREAS, the Company is a bio-technology company in the business of developing anti-a

November 13, 2017 EX-10.13

Consulting Agreement between the Company and Grant Young, dated December 30, 2016(8)

Exhibit 10.13 PROTOKINETIX, INCORPORATED CONSULTING AGREEMENT This CONSULTING AGREEMENT (the “Agreement”) is made and entered into as of December 30, 2016 and made effective as of January 1, 2017 (the “Effective Date”), by and between ProtoKinetix, Incorporated, a Nevada corporation (“Company”), and Grant Young, an individual (“Consultant”). WHEREAS, the Company is a bio-technology company in the

November 13, 2017 10-Q

PKTX / ProtoKinetix, Inc. FORM 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2017 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission file number: PROTOKINETIX, INCORPORATED (E

November 9, 2017 EX-10.1

Settlement Agreement and General Release between ProtoKinetix, Incorporated and Susan M. Woodward, dated November 3, 20177

Exhibit 10.1 SETTLEMENT AGREEMENT AND GENERAL RELEASE This Agreement and General Release (this ?Agreement?) is made and entered into as of the 3 rd day of November 2017, between ProtoKinetix Incorporated, a Nevada corporation, (the ?Company?) and Susan M. Woodward, (the ?Consultant?), an Ohio resident. RECITALS A. The Consultant has provided services to the Company pursuant to a consulting agreeme

November 9, 2017 EX-10.3

Unsecured Promissory Note issued by ProtoKinetix, Incorporated to Clarence E. Smith dated November 3, 2017.7

Exhibit 10.3 THIS UNSECURED PROMISSORY NOTE HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 OR APPLICABLE STATE BLUE SKY OR SECURITIES LAWS AND WAS OFFERED UNDER AN EXEMPTION FROM THE REGISTRATION PROVISIONS OF SUCH LAWS. THIS UNSECURED PROMISSORY NOTE CANNOT BE SOLD, TRANSFERRED, ASSIGNED OR OTHERWISE DISPOSED OF EXCEPT IN COMPLIANCE APPLICABLE FEDERAL AND STATE SECURITIES LAWS. Unsecure

November 9, 2017 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Entry into a Material Definitive Agreement, Termination of a Material Definitive Agreement, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: November 3, 2017 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Ide ntification No. 9176 South

November 9, 2017 EX-10.2

Unsecured Promissory Note issued by ProtoKinetix, Incorporated to Clarence E. Smith dated October 23, 2017.7

Exhibit 10.2 THIS UNSECURED PROMISSORY NOTE HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 OR APPLICABLE STATE BLUE SKY OR SECURITIES LAWS AND WAS OFFERED UNDER AN EXEMPTION FROM THE REGISTRATION PROVISIONS OF SUCH LAWS. THIS UNSECURED PROMISSORY NOTE CANNOT BE SOLD, TRANSFERRED, ASSIGNED OR OTHERWISE DISPOSED OF EXCEPT IN COMPLIANCE APPLICABLE FEDERAL AND STATE SECURITIES LAWS. Unsecure

September 12, 2017 EX-10.2

First Amendment to Consulting Agreement between Edward P. McDonough and the Company dated September 1, 2017

Exhibit 10.2 AMENDMENT TO DIRECTOR CONSULTING AGREEMENT This Amendment to the Director Consulting Agreement (the ?Amendment?) is entered into on September 1, 2017 (?Effective Date?), by and between Edward P. McDonough (the ?Consultant?) and ProtoKinetix, Incorporated (the ?Company?). RECITALS WHEREAS, the Consultant and the Company entered into that certain Director Consulting Agreement effective

September 12, 2017 EX-10.1

First Amendment to Consulting Agreement between Clarence E. Smith and the Company dated September 1, 2017(8)

Exhibit 10.1 AMENDMENT TO CONSULTING AGREEMENT This Amendment to the Consulting Agreement (the ?Amendment?) is entered into on September 1, 2017 (?Effective Date?), by and between Clarence E. Smith (the ?Consultant?) and ProtoKinetix, Incorporated (the ?Company?). RECITALS WHEREAS, the Consultant and the Company entered into that certain Consulting Agreement effective January 1, 2017 (the ?Consult

September 12, 2017 EX-10.3

First Amendment to Consulting Agreement between Grant Young and the Company dated September 1, 2017(8)

Exhibit 10.3 AMENDMENT TO CONSULTING AGREEMENT This Amendment to the Consulting Agreement (the ?Amendment?) is entered into on September 1, 2017 (?Effective Date?), by and between Grant Young (the ?Consultant?) and ProtoKinetix, Incorporated (the ?Company?). RECITALS WHEREAS, the Consultant and the Company entered into that certain Consulting Agreement effective January 1, 2017 (the ?Consulting Ag

September 12, 2017 8-K/A

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K/A CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: September 1, 2017 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 705 Dugan

September 7, 2017 EX-10.1

First Amendment to Consulting Agreement between Clarence E. Smith and the Company dated September 1, 2017(9)

Exhibit 10.1 AMENDMENT TO CONSULTING AGREEMENT This Amendment to the Consulting Agreement (the ?Amendment?) is entered into on September 1, 2017 (?Effective Date?), by and between Clarence E. Smith (the ?Consultant?) and ProtoKinetix, Incorporated (the ?Company?). RECITALS WHEREAS, the Consultant and the Company entered into that certain Consulting Agreement effective January 1, 2017 (the ?Consult

September 7, 2017 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: September 1, 2017 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 705 Dugan R

September 7, 2017 EX-10.2

First Amendment to Consulting Agreement between Edward P. McDonough and the Company dated September 1, 2017(9)

Exhibit 10.2 AMENDMENT TO DIRECTOR CONSULTING AGREEMENT This Amendment to the Director Consulting Agreement (the ?Amendment?) is entered into on September 1, 2017 (?Effective Date?), by and between Edward P. McDonough (the ?Consultant?) and ProtoKinetix, Incorporated (the ?Company?). RECITALS WHEREAS, the Consultant and the Company entered into that certain Director Consulting Agreement effective

September 7, 2017 EX-10.3

First Amendment to Consulting Agreement between Grant Young and the Company dated September 1, 2017(9)

Exhibit 10.3 AMENDMENT TO CONSULTING AGREEMENT This Amendment to the Consulting Agreement (the ?Amendment?) is entered into on September 1, 2017 (?Effective Date?), by and between Grant Young (the ?Consultant?) and ProtoKinetix, Incorporated (the ?Company?). RECITALS WHEREAS, the Consultant and the Company entered into that certain Consulting Agreement effective January 1, 2017 (the ?Consulting Ag

August 8, 2017 10-Q

PKTX / ProtoKinetix, Inc. FORM 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2017 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission file number: PROTOKINETIX, INCORPORATED (Exact

May 12, 2017 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2017 ☐ TRANSITION REPORT UNDER SECTI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2017 OR ? TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission file number: PROTOKINETIX, INCORPORATED (Exact

February 21, 2017 EX-4.2

2017 Stock Option and Stock Bonus Plan3

Exhibit 4.2 PROTOKINETIX, INCORPORATED 2017 STOCK OPTION AND STOCK BONUS PLAN 1. Purposes of and Benefits Under the Plan. This 2017 Stock Option and Stock Bonus Plan (the "Plan") is intended to encourage stock ownership by employees, consultants, officers and directors of ProtoKinetix, Incorporated and its controlled, affiliated and subsidiary entities (collectively, the "Corporation"), so that th

February 21, 2017 EX-10.9

Consulting Agreement between the Company and Clarence E. Smith, dated December 30, 2016(7)

Exhibit 10.9 PROTOKINETIX, INCORPORATED CONSULTING AGREEMENT This CONSULTING AGREEMENT (the "Agreement") is made and entered into as of December 30, 2016 and made effective as of January 1, 2017 (the "Effective Date"), by and between ProtoKinetix, Incorporated, a Nevada corporation ("Company"), and Clarence E. Smith, an individual ("Consultant"). WHEREAS, the Company is a bio-technology company in

February 21, 2017 EX-10.10

Consulting Agreement between the Company and Susan M. Woodward, dated December 30, 20163

Exhibit 10.10 PROTOKINETIX, INCORPORATED CONSULTING AGREEMENT This CONSULTING AGREEMENT (the "Agreement") is made and entered into as of December 30, 2016 and made effective as of January 1, 2017 (the "Effective Date"), by and between ProtoKinetix, Incorporated, a Nevada corporation ("Company"), and Susan M. Woodward, an individual ("Consultant"). WHEREAS, the Company is a bio-technology company i

February 21, 2017 EX-10.11

Director Consulting Agreement between the Company and Edward P. McDonough, dated December 30, 2016(7)

Exhibit 10.11 PROTOKINETIX, INCORPORATED DIRECTOR CONSULTING AGREEMENT This DIRECTOR CONSULTING AGREEMENT (the "Agreement") is made and entered into as of December 30, 2016 and made effective as of January 1, 2017 (the "Effective Date"), by and between ProtoKinetix, Incorporated, a Nevada corporation ("Company"), and Edward P. McDonough, an individual (the "Director"). WHEREAS, the Company is a bi

February 21, 2017 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2016 [] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INCORPORATED (Name

January 24, 2017 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: January 17, 2017 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 9176 South P

January 5, 2017 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: November 30, 2016 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 9176 South

January 5, 2017 SC 13G/A

PKTX / ProtoKinetix, Inc. / Young Lachlan Grant - SCHEDULE 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* ProtoKinetix, Incorporated (Name of Issuer) Common Stock, $0.0000053 par value per share (Title of Class Securities) 743722100 (CUSIP NUMBER) January 1, 2017 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate t

December 23, 2016 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

SC 13D/A 1 pktx13da.htm SCHEDULE 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A (Amendment No. 8)* Under the Securities Exchange Act of 1934 PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1845 County Road #214 St. Augustine, Florida 32084

December 22, 2016 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A (Amendment No. 7)* Under the Securities Exchange Act of 1934 PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1845 County Road #214 St. Augustine, Florida 32084 304-299-5070 (Name, Address and Teleph

December 7, 2016 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A (Amendment No. 6)* Under the Securities Exchange Act of 1934 PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1845 County Road #214 St. Augustine, Florida 32084 304-299-5070 (Name, Address and Teleph

November 14, 2016 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2016 ☐ TRANSITION REPORT UNDER S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2016 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission file number: PROTOKINETIX, INCORPORATED (E

November 8, 2016 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

SC 13D/A 1 pktx13da.htm SCHEDULE 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A (Amendment No. 5)* Under the Securities Exchange Act of 1934 PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1845 County Road #214 St. Augustine, Florida 32084

September 19, 2016 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

SC 13D/A 1 pktx13da.htm SCHEDULE 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A (Amendment No. 4)* Under the Securities Exchange Act of 1934 PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1845 County Road #214 St. Augustine, Florida 32084

August 15, 2016 EX-10.9

Universal Agreement between the Company and Grant Young, dated May 20, 20169

Exhibit 10.9 UNIVERSAL ASSIGNMENT WHEREAS I, Grant YOUNG, whose full address is: - 6438 Rosebery Avenue, West Vancouver, BC V7W 2C6 Canada; has invented certain new and useful improvements in an invention entitled "USE OF ANTI-AGING GLYCOPROTEIN FOR ENHANCING SURVIVAL OF NEUROSENSORY PRECURSOR CELLS" for which a patent application(s) was / were filed as listed on Schedule A attached hereto. AND WH

August 15, 2016 EX-10.11

EX-10.11

Exhibit 10.11

August 15, 2016 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2016 ☐ TRANSITION REPORT UNDER SECTIO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2016 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission file number: PROTOKINETIX, INCORPORATED (Exact

August 15, 2016 EX-10.11

EX-10.11

Exhibit 10.11

August 15, 2016 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2016 ☐ TRANSITION REPORT UNDER SECTIO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2016 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission file number: PROTOKINETIX, INCORPORATED (Exact

August 15, 2016 EX-10.10

Collaborative Research Agreement between the Company and the University of British Columbia, dated May 31, 2016(5)

Exhibit 10.10 COLLABORATIVE RESEARCH AGREEMENT BETWEEN: THE UNIVERSITY OF BRITISH COLUMBIA, a corporation continued under the University Act of British Columbia with offices at 103 – 6190 Agronomy Road, Vancouver, British Columbia, V6T 1Z3 (“UBC”) AND VANCOUVER COASTAL HEALTH AUTHORITY, a regional health board established under the Health Authorities Act (British Columbia) having its research admi

July 11, 2016 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A (Amendment No. 3)* Under the Securities Exchange Act of 1934 PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1845 County Road #214 St. Augustine, Florida 32084 304-299-5070 (Name, Address and Teleph

June 16, 2016 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: June 16, 2016 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 9176 South Plea

June 7, 2016 EX-99.1

ProtoKinetix’ AAGP™ has been Published in the Journal of Tissue Engineering and Regenerative Medicine

Exhibit 99.1 ProtoKinetix? AAGP? has been Published in the Journal of Tissue Engineering and Regenerative Medicine St. Marys, West Virginia, June 7, 2016 ProtoKinetix, Incorporated (OTCQB: PKTX) (the "Company" or "ProtoKinetix") ( www.protokinetix.com) is pleased to announce that a paper submitted by Dr. Kevin Gregory-Evans on ProtoKinetix? AAGP? has been published in the Journal of Tissue Enginee

June 7, 2016 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: May 20, 2016 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 9176 South Pleas

May 16, 2016 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2016 ☐ TRANSITION REPORT UNDER SECTI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2016 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission file number: PROTOKINETIX, INCORPORATED (Exact

May 16, 2016 EX-10.8

ITR MASTER CONTRACT

Exhibit 10.8 ITR MASTER CONTRACT By and Between: ITR Laboratories Canada Inc. 19601 boul. Clark Graham, Baie d?Urfe, Quebec, H9X 3T1, Canada Tel: (514) 457-7400 Fax: (514) 457-7303 (?ITR?) By and Between: The Sponsor Name: ProtoKinetix, Incorporated Address: 9176 South Pleasants Highway Tel: 304-299-5070 Contact Person: Clarence E. Smith Title: President and CEO E-mail: [email protected] (th

May 5, 2016 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A (Amendment No. 2)* Under the Securities Exchange Act of 1934 PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1845 County Road #214 St. Augustine, Florida 32084 304-299-5070 (Name, Address and Teleph

May 3, 2016 EX-99.1

Form 51-105Fl Notice -OTC Issuer Ceases to be an OTC Reporting Issuer

Exhibit 99.1 Form 51-105Fl Notice -OTC Issuer Ceases to be an OTC Reporting Issuer This is the form required under paragraph 4 (1) (d) of Multilateral Instrument 51-105 Issuers Quoted in the Us. Over-the-Counter Markets for an a TC issuer to give notice that it has ceased to be an aTC reporting issuer under section 3 of the Instrument in a jurisdiction other than Quebec. In Quebec, an aTC reportin

May 3, 2016 8-K

ProtoKinetix FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: May 2, 2016 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 9176 South Pleasa

May 3, 2016 EX-99.2

AAGP™ Improves Results in Stem Cells Transplanted in Retina Tissue by 300%

Exhibit 99.2 AAGP? Improves Results in Stem Cells Transplanted in Retina Tissue by 300% St. Marys, West Virginia, May 2, 2016 ProtoKinetix, Incorporated (OTCQB: PKTX) (the "Company" or "ProtoKinetix") ( www.protokinetix.com) is pleased to announce that a paper submitted by Dr. Kevin Gregory-Evans on ProtoKinetix? AAGP? has been accepted by the Journal of Tissue Engineering and Regenerative Medicin

April 26, 2016 EX-99.1

ProtoKinetix Outlines Steps to Clinical Trial Application for AAGP™

Exhibit 99.1 ProtoKinetix Outlines Steps to Clinical Trial Application for AAGP? St. Marys, West Virginia, April 26, 2016 ProtoKinetix, Incorporated (OTCQB: PKTX) (the "Company" or "ProtoKinetix") ( www.protokinetix.com) outlines the steps to be completed for the application to conduct a clinical trial in Canada. For the last four years ProtoKinetix has been involved in a collaboration with the La

April 26, 2016 8-K

ProtoKinetix FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: April 26, 2016 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 9176 South Ple

April 22, 2016 SC 13G

PKTX / ProtoKinetix, Inc. / Young Lachlan Grant - SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* ProtoKinetix, Incorporated (Name of Issuer) Common Stock, $0.0000053 par value per share (Title of Class Securities) 743722100 (CUSIP NUMBER) January 1, 2016 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate th

March 30, 2016 EX-10.6

PROTOKINETIX, INCORPORATED CONSULTING AGREEMENT

EX-10.6 3 ex10x6.htm EXHIBIT 10.6 Exhibit 10.6 PROTOKINETIX, INCORPORATED CONSULTING AGREEMENT This CONSULTING AGREEMENT (the “Agreement”) is made and entered into as of December 21, 2015 and made effective as of January 1, 2016 (the “Effective Date”), by and between ProtoKinetix, Incorporated, a Nevada corporation (“Company”), and Susan M. Woodward, an individual (“Consultant”). WHEREAS, the Comp

March 30, 2016 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2015 [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INCORPORATED (Name

March 30, 2016 EX-10.7

PROTOKINETIX, INCORPORATED DIRECTOR CONSULTING AGREEMENT

Exhibit 10.7 PROTOKINETIX, INCORPORATED DIRECTOR CONSULTING AGREEMENT This DIRECTOR CONSULTING AGREEMENT (the ?Agreement?) is made and entered into as of December 23, 2015 and made effective as of January 1, 2016 (the ?Effective Date?), by and between ProtoKinetix, Incorporated, a Nevada corporation (?Company?), and Edward P. McDonough, an individual (the ?Director?). WHEREAS, the Company is a bio

March 30, 2016 EX-10.5

PROTOKINETIX, INCORPORATED CONSULTING AGREEMENT

Exhibit 10.5 PROTOKINETIX, INCORPORATED CONSULTING AGREEMENT This CONSULTING AGREEMENT (the ?Agreement?) is made and entered into as of December 21, 2015 and made effective as of January 1, 2016 (the ?Effective Date?), by and between ProtoKinetix, Incorporated, a Nevada corporation (?Company?), and Clarence E. Smith, an individual (?Consultant?). WHEREAS, the Company is a bio-technology company in

January 6, 2016 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: December 21, 2015 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 9176 South

January 6, 2016 EX-99.1

ProtoKinetix Corporate Update

Exhibit 99.1 ProtoKinetix Corporate Update St. Marys, West Virginia, January 5, 2016 ProtoKinetix, Incorporated (OTCQB: PKTX) (the "Company" or "ProtoKinetix") ( www.protokinetix.com) is pleased to provide the following corporate update to its stockholders: Fiscal 2015 was a year of significant progress for ProtoKinetix, Incorporated. We executed several complex initiatives and continued to make g

November 16, 2015 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2015 ☐ TRANSITION REPORT UNDER S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2015 OR ? TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission file number: PROTOKINETIX, INCORPORATED (E

August 14, 2015 EX-4.1

2015 Stock Option and Stock Bonus Plan2

Exhibit 4.1 PROTOKINETIX, INCORPORATED 2015 STOCK OPTION AND STOCK BONUS PLAN 1. Purposes of and Benefits Under the Plan. This 2015 Stock Option and Stock Bonus Plan (the "Plan") is intended to encourage stock ownership by employees, consultants, officers and directors of ProtoKinetix, Incorporated and its controlled, affiliated and subsidiary entities (collectively, the "Corporation"), so that th

August 14, 2015 EX-10.3

PROTOKINETIX, INCORPORATED DIRECTOR CONSULTING AGREEMENT

Exhibit 10.3 PROTOKINETIX, INCORPORATED DIRECTOR CONSULTING AGREEMENT This DIRECTOR CONSULTING AGREEMENT (the "Agreement") is made and entered into as of July 1, 2015 (the "Effective Date"), by and between ProtoKinetix, Incorporated, a Nevada corporation ("Company"), and Edward P. McDonough, an individual the ("Director"). WHEREAS, the Company is a bio-technology company in the business of develop

August 14, 2015 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2015 ☐ TRANSITION REPORT UNDER SECTIO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2015 OR ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission file number: PROTOKINETIX, INCORPORATED (Exact

July 8, 2015 SC 13D/A

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D/A Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A (Amendment No. 1)* Under the Securities Exchange Act of 1934 PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1845 County Road #214 St. Augustine, Florida 32084 304-299-5070 (Name, Address and Teleph

July 7, 2015 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Unregistered Sales of Equity Securities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: June 30, 2015 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 9176 South Plea

May 20, 2015 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ☑ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2015 ☐ TRANSITION REPORT UNDER SECTI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2015 OR ? TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission file number: PROTOKINETIX, INCORPORATED (Exact

May 20, 2015 EX-10.6

TECHNOLOGY TRANSFER AGREEMENT

EX-10.6 2 ex10x6.htm EXHIBIT 10.6 Exhibit 10.6 TECHNOLOGY TRANSFER AGREEMENT THIS AGREEMENT made as of the 22nd day of April, 2015. BETWEEN: GRANT YOUNG, having an address for delivery and service located at 6438 Rosebery, West Vancouver, BC V7W 2C6 (the “Consultant”); OF THE FIRST PART AND: PROTOKINETIX, INC. a Nevada company having its address for notices hereunder at c/o 9176 South Pleasant Hig

May 18, 2015 NT 10-Q

ProtoKinetix NOTIFICATION OF LATE FILING

photont10q.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 SEC FILE NUMBER CUSIP NUMBER NOTIFICATION OF LATE FILING (Check one:) ? Form 10-K ? Form 20-F ? Form 11-K ? Form 10-Q ? Form 10-D ? Form N-SAR For Period Ended: March 31, 2015 ? Transition Report on Form 10-K ? Transition Report on Form 20-F ? Transition Report on Form 11-K ? Transition Report on For

May 1, 2015 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: April 30, 2015 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 9176 South Ple

April 27, 2015 8-K

Entry into a Material Definitive Agreement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: April 22, 2015 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 9176 South Ple

April 14, 2015 EX-10.5

PROTOKINETIX, INCORPORATED CONSULTING AGREEMENT

Exhibit 10.5 PROTOKINETIX, INCORPORATED CONSULTING AGREEMENT This CONSULTING AGREEMENT (the ?Agreement?) is made and entered into as of March 30, 2015 and made effective as of January 1, 2015 (the ?Effective Date?), by and between ProtoKinetix, Incorporated, a Nevada corporation (?Company?), and Susan M. Woodward, an individual (?Consultant?). WHEREAS, the Company is a bio-technology company in th

April 14, 2015 EX-10.2

Royalty Agreement between the Company and The Governors of the University of Alberta, dated April 8, 2015(4)

Exhibit 10.2 INSI INSTITUT NATIONAL DES SCIENCES APPLIQUEES ROUEN Saint Etienne du Rouvray, Ie 28 Octobre 2014 Direction de la Recherche et de la Valorisation Affaire suivie par Mme JOUETTE/Mme VANDER EECKEN Tel: 02 32 95 66 62 [email protected] Objet: Cession de brevets Monsieur, L'INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE ROUEN(INSA) de 685 avenue de l'Universite, BP08, 76801, Sain

April 14, 2015 10-K

Assignment of Patents and Patent Application between the Company and Institut National des Sciences Appliquées de Rouen dated January 5, 20153

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K ☑ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2014 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INCORPORATED (Name of

April 14, 2015 EX-10.6

Royalty Agreement between the Company and The Governors of the University of Alberta, dated April 8, 2015(3)

Exhibit 10.6 ROYALTY AGREEMENT This agreement made as of the 23rd day of March, 2015 ("Effective Date") BETWEEN: Protokinetix Incorporated a corporation pursuant to the laws of Nevada having an address for receipt of notices at 9176 South Pleasants Highway, St. Marys, WV, USA 26170 (hereinafter called "Protokinetix") The Governors of The University Of Alberta a university incorporated under the Po

April 14, 2015 EX-10.6

EX-10.6

April 14, 2015 EX-10.4

PROTOKINETIX, INCORPORATED CONSULTING AGREEMENT

Exhibit 10.4 PROTOKINETIX, INCORPORATED CONSULTING AGREEMENT This CONSULTING AGREEMENT (the ?Agreement?) is made and entered into as of March 30, 2015 and made effective as of January 1, 2015 (the ?Effective Date?), by and between ProtoKinetix, Incorporated, a Nevada corporation (?Company?), and Clarence E. Smith, an individual (?Consultant?). WHEREAS, the Company is a bio-technology company in th

April 14, 2015 EX-10.3

SETTLEMENT AND INDEMNITY AGREEMENT IBIS AGREEMENT dated for reference 2nd day of March, 2015.

Exhibit 10.3 SETTLEMENT AND INDEMNITY AGREEMENT IBIS AGREEMENT dated for reference 2nd day of March, 2015. BETWEEN: Protokinetix, Inc. having a business address at 9176 South Pleasant Highway, St. Marys, West Virginia, USA261 70 (the "Company") AND OF THE FIRST PART Standard Bankcorp Inc. having a business address at 6528 Wellington Place, West Vancouver, BC V7W 2Jl (the "Creditor") OF THE SECOND

April 14, 2015 EX-10.3

EX-10.3

April 14, 2015 8-K

ProtoKinetix FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: April 8, 2015 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 9176 South Plea

April 7, 2015 8-K

Entry into a Material Definitive Agreement, Completion of Acquisition or Disposition of Assets

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: April 3, 2015 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 9176 South Plea

April 3, 2015 8-K

ProtoKinetix FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: March 30, 2015 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 9176 South Ple

April 1, 2015 NT 10-K

ProtoKinetix NOTIFICATION OF LATE FILING

photont10q.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 SEC FILE NUMBER CUSIP NUMBER NOTIFICATION OF LATE FILING (Check one:) ? Form 10-K ? Form 20-F ? Form 11-K ? Form 10-Q ? Form 10-D ? Form N-SAR For Period Ended: December 31, 2014 ? Transition Report on Form 10-K ? Transition Report on Form 20-F ? Transition Report on Form 11-K ? Transition Report on

March 25, 2015 SC 13D

PKTX / ProtoKinetix, Inc. / SMITH CLARENCE EDWARD - SCHEDULE 13D Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 PROTOKINETIX, INCORPORATED (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Securities) 743722100 (CUSIP Number) Clarence E. Smith 1845 County Road #214 St. Augustine, Florida 32084 304-299-5070 (Name, Address and Telephone Number of Person

March 9, 2015 8-K

ProtoKinetix FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: March 2, 2015 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No 9176 South Pleas

February 26, 2015 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: February 25, 2015 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No. 9176 South

February 24, 2015 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Entry into a Material Definitive Agreement, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: February 19, 2015 ProtoKinetix, Incorporated (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 State of Incorporation Commission File Number IRS Employer Identification No 9176 South P

November 14, 2014 10-Q

UNITED STATES SECURITIES AND EXCHANGE C OMMISSION Washington, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2014 [ ] TRANSITION REPORT UNDER SEC

UNITED STATES SECURITIES AND EXCHANGE C OMMISSION Washington, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2014 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94

November 6, 2014 EX-99

EX-99

Converted by EDGARwiz

November 6, 2014 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported) October 27 2014 - PROTOKINETIX, INC.

November 6, 2014 EX-99

October 27, 2014

October 27, 2014 October 27, 2014 Intrepid Innovations Corporation 4654 SR 64 E Penthouse Suite 127 Bradenton, Florida 34208 Gentlemen: ProtoKinetix hereby declares the Agreement to Sell Rights for AAGP Blood Preservative Applications (“Agreement”) made March 4, 2014, to be null and void.

October 8, 2014 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

United States Securities and Exchange Commission Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15[d] of the Securities Exchange Act of 1934 October 8, 2014 Date of Report PROTOKINETIX, INC. (Exact name of Registrant as specified in its Charter) Nevada 000-32917 94-3355026 (State or Other Jurisdiction of (Commission File Number) (I.R.S. Employer Identification No.) Incorp

August 14, 2014 10-Q

UNITED STATES SECURITIES AND EXCHANGE C OMMISSION Washington, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2014 [ ] TRANSITION REPORT UNDER SECTION

UNITED STATES SECURITIES AND EXCHANGE C OMMISSION Washington, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2014 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355

June 25, 2014 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers - FORM 8-K

Protokinetix, Inc.: Form 8-K - Filed by newsfilecorp.com UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) June 25, 2014 PROTOKINETIX, INC. (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 (State or o

June 5, 2014 10-Q

UNTED STATES SECURITIES AND EXCHANGE C OMMISSION Washington, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2014 [ ] TRANSITION REPORT UNDER SECTION

UNTED STATES SECURITIES AND EXCHANGE C OMMISSION Washington, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2014 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355

May 27, 2014 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2013 [ ] TRANSITION REPORT PURSUANT TO S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2013 [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INC. (Name

May 15, 2014 10-Q

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE QUARTERLY PERIOD ENDED SEPTEMBER 30, 2013 [ ] TRANSITION REPORT UNDER SECTION 13 O

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE QUARTERLY PERIOD ENDED SEPTEMBER 30, 2013 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026

May 14, 2014 10-Q

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2013 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15

10-Q 1 form10q.htm FORM 10-Q U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2013 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX

May 14, 2014 10-Q

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2013 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2013 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026 (Stat

April 30, 2014 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2012 [ ] TRANSITION REPORT PURSUANT TO SECTION 1

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2012 [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INC. (Name of smal

November 15, 2012 10-Q

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30,2012 [ ] TRANSITION REPORT UNDER SECTION 13 OR

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30,2012 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026 (

November 15, 2012 NT 10-Q

- NOTIFICATION OF LATE FILING

Protokinetix, Inc.: Form 12b-25 - Filed by newsfilecorp.com UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING (Check one): [ ] Form 10-K [ ] Form 20-F [ ] Form 11-K [ x ] Form 10-Q [ ] Form 10-D [ ] Form N-SAR [ ] Form N-CSR For Period Ended: September 30, 2012 [ ] Transition Report on Form 10-K [ ] Transition Report on Form 20-F [ ] Tr

August 20, 2012 10-Q/A

UNITED STATES SECURITIES AND EXCHANGE C OMMISSION WASHINGTON, D.C. 20549 FORM 10-Q/A [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2012 [ ] TRANSITION REPORT UNDER SECTIO

UNITED STATES SECURITIES AND EXCHANGE C OMMISSION WASHINGTON, D.C. 20549 FORM 10-Q/A [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2012 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-33

August 14, 2012 10-Q

UNITED STATES SECURITIES AND EXCHANGE C OMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30,2012 [ ] TRANSITION REPORT UNDER SECTION 1

UNITED STATES SECURITIES AND EXCHANGE C OMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30,2012 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-33550

May 15, 2012 10-Q

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2012 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2012 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026 (Sta

March 20, 2012 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2011 [ ] TRANSITION REPORT PURSUANT TO S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2011 [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INC. (Name

February 14, 2012 SC 13G/A

PKTX / ProtoKinetix, Inc. / Empire Capital Management, L.L.C. Passive Investment

FORM SC 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Amendment No.6 PROTOKINETIX INC (Name of Issuer) Common Stock, $0.0000053 par value per share (Title of Class of Securities) 743722100 (CUSIP Number) December 31, 2011 (Date of event which requires filing of this statement) Check the appropriate box to designate the rule pursuant to which this Schedule 13G is fi

November 14, 2011 10-Q

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2011 [ ] TRANSITION REPORT UNDER SECTION 13 O

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2011 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026

August 15, 2011 10-Q

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2011 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2011 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026 (Stat

May 16, 2011 10-Q

UNITED STATES SECURITIES AND EXCHANGE C OMMISSION Washington, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2011 [ ] TRANSITION REPORT UNDER SECTION

UNITED STATES SECURITIES AND EXCHANGE C OMMISSION Washington, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2011 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-335

March 29, 2011 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2010 [ ] TRANSITION REPORT PURSUANT TO SECTION 1

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2010 [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INC. (Name of smal

February 15, 2011 SC 13G/A

SECURITIES & EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) Amendment No. 5 INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO 13d-2(b) UNDER THE SEC

SECURITIES & EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) Amendment No. 5 INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO 13d-2(b) UNDER THE SECURITIES EXCHANGE ACT OF 1934 PROTOKINETIX INC (Name of Issuer) Common Stock, $0.0000053 par value (Title of Class of Securities) 743722100 (CUSIP Numb

January 24, 2011 CORRESP

January 24, 2011

January 24, 2011 United States Securities and Exchange Commission 100 F Street, NE Washington, DC 20549 Attention: Jim B.

January 24, 2011 10-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K/A [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2009 [ ] TRANSITION REPORT PURSUANT TO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K/A [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2009 [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INC. (Na

December 14, 2010 10-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K/A [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2009 [ ] TRANSITION REPORT PURSUANT TO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K/A [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2009 [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INC. (Na

December 14, 2010 CORRESP

2

December 9, 2010 VIA EDGAR FILING United States Securities and Exchange Commission 100 F Street, N.

November 8, 2010 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2010 [ ] TRANSITION REPORT UNDER SECT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2010 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. (Exact nam

August 11, 2010 10-Q

U. S. SECURITIES AND EXCHANGE C OMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

U. S. SECURITIES AND EXCHANGE C OMMISSION WASHINGTON, D.C. 20549 FORM 10-Q T QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2010 o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026 (State o

May 14, 2010 10-Q

U. S. SECURITIES AND EXCHANGE C OMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

U. S. SECURITIES AND EXCHANGE C OMMISSION WASHINGTON, D.C. 20549 FORM 10-Q x QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2010 o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026 (State

March 11, 2010 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K T ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2009 £ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INC. (Name of small bu

February 16, 2010 SC 13G/A

SECURITIES & EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) Amendment No. 4 INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO 13d-2(b) UNDER THE SEC

SECURITIES & EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) Amendment No. 4 INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO 13d-2(b) UNDER THE SECURITIES EXCHANGE ACT OF 1934 PROTOKINETIX INC (Name of Issuer) Common Stock, $0.0000053 par value (Title of Class of Securities) 743722100 (CUSIP Numb

November 13, 2009 10-Q

U. S. SECURITIES AND EXCHANGE C OMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

U. S. SECURITIES AND EXCHANGE C OMMISSION WASHINGTON, D.C. 20549 FORM 10-Q x QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2009 o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026 (St

August 6, 2009 10-Q

U. S. SECURITIES AND EXCHANGE C OMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

U. S. SECURITIES AND EXCHANGE C OMMISSION WASHINGTON, D.C. 20549 FORM 10-Q x QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2009 o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026 (State o

May 15, 2009 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K T ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2008 o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INC. (Name of small bu

May 15, 2009 10-Q

U. S. SECURITIES AND EXCHANGE C OMMISSION WASHINGTON, D.C. 20549 FORM 10-Q T QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2009 £ TRANSITION REPORT UNDER SECTION 13 OR 15(d)

U. S. SECURITIES AND EXCHANGE C OMMISSION WASHINGTON, D.C. 20549 FORM 10-Q T QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2009 £ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026 (State

May 7, 2009 8-K/A

Changes in Registrant's Certifying Accountant

8-K/A 1 form8ka.htm PROTOKINETIX, INC 8KA 4-17-2008 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A AMENDED CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) April 17, 2008 PROTOKINETIX, INC. (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 (Stat

May 7, 2009 CORRESP

May 6, 2009

May 6, 2009 Protokinetix, Inc. 2225 Folkstone Way West Vancouver, British Columbia V7S 2Y6 United States Securities and Exchange Commission 100 F Street NE Washington, D.C. 20549-7010 Attention: Tabatha Akins, Staff Accountant Re: Protokinetix, Inc.; Item 4.01 Form 8-K; filed April 20, 2009; file number 000.32917 Dear Ms. Akins: Please be informed that we have received and reviewed your letter dat

May 1, 2009 CORRESP

May 1, 2009

May 1, 2009 Protokinetix, Inc. 2225 Folkstone Way West Vancouver, British Columbia V7S 2Y6 United States Securities and Exchange Commission 100 F Street NE Washington, D.C. 20549-7010 Attention: Tabatha Akins, Staff Accountant Re: Protokinetix, Inc.; your file number 000-32917 Dear Ms. Akins: Please be informed that we have received and reviewed your letter dated April 23, 2009, regarding our Form

April 20, 2009 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) April 17, 2008 PROTOKINETIX, INC. (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 (State or other jurisdiction of incorporation) (Commission File Num

March 31, 2009 NT 10-K

FORM 12b-25

United States Securities and Exchange Commission Washington, D.C. 20549 FORM 12b-25 Notification of Late Filing (Amendment No. 0)* OMB Number 3234-0058 SEC File Number CUSIP Number (Check one): ? Form 10-K Form 20-F Form 11-K Form 10-Q Form 10-D Form N-SAR Form N-CSR For Period Ended: December 31, 2008 Transition Report on Form 10-K Transition Report on Form 20-F Transition Report on Form 11-K Tra

February 13, 2009 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* PROTOKINETIX INC COM (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Se

OMB APPROVAL OMB Number: 3235-0145 Expires: February 28, 2009 Estimated average burden hours per response.

November 13, 2008 10-Q

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q x QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2008

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q x QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2008 £ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026 (Sta

August 15, 2008 10-Q

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q x QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2008 ¨ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026 (State or

August 15, 2008 NT 10-Q

FORM 12b-25

United States Securities and Exchange Commission Washington, D.C. 20549 FORM 12b-25 Notification of Late Filing (Amendment No. 0)* OMB Number 3234-0058 SEC File Number CUSIP Number (Check one): Form 10-K Form 20-F Form 11-K ? Form 10-Q Form 10-D Form N-SAR Form N-CSR For Period Ended: June 30, 2008 Transition Report on Form 10-K Transition Report on Form 20-F Transition Report on Form 11-K Transit

May 20, 2008 10-Q

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2008 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026 (Sta

May 15, 2008 NT 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING (Check one): [ ] Form 10-KSB [ ] Form 20-F [ ] Form 11-K [ X ] Form 10-Q [ ] Form N-SAR For Period Ended: [ ] Transition Report on Form 10

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING (Check one): [ ] Form 10-KSB [ ] Form 20-F [ ] Form 11-K [ X ] Form 10-Q [ ] Form N-SAR For Period Ended: [ ] Transition Report on Form 10-K [ ] Transition Report on Form 20-F [ ] Transition Report on Form 11-K [ ] Transition Report on Form 10-Q [ ] Transition Report on Form N-SAR For th

May 2, 2008 10KSB/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-KSB/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-KSB/A [ X ] Annual Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 for the fiscal year ended December 31, 2004, or [ ] Transitional Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 for the transition period from to . Commission File No. 0-32917 PROTOKINETIX, INC. Formerly known as

May 2, 2008 10QSB/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-QSB/A (Mark One)

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-QSB/A (Mark One) [ X ] Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 for the quarterly period ended March 31, 2004 or [ ] Transitional Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 for the transition period from to . Commission File No. 0-32917 PROTOKINETIX, INC. a

May 2, 2008 10KSB/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FIRST AMENDED FORM 10-KSB/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FIRST AMENDED FORM 10-KSB/A (Mark One) [ X ] Annual Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 for the fiscal year ended December 31, 2003. [ ] Transitional Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 for the transition period from to . Commission File No. 0-32917 PROTOKINETIX,

May 1, 2008 10QSB/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-QSB/A (Mark One) [ X ] Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 for the quarterly period ended March 31, 2005 or [ ] Transitional Report

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-QSB/A (Mark One) [ X ] Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 for the quarterly period ended March 31, 2005 or [ ] Transitional Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 for the transition period Commission File No. 0-32917 PROTOKINETIX, INC. (Name of sma

May 1, 2008 10QSB/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-QSB/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-QSB/A [ X ] Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 for the quarterly period ended June 30, 2005 or [ ] Transitional Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 for the transition period from to . Commission File No. 0-32917 PROTOKINETIX, INC. (Name of small

May 1, 2008 10QSB/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-QSB/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-QSB/A [ X ] Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 for the quarterly period ended September 30, 2005 or [ ] Transitional Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 for the transition period from to . Commission File No. 0-32917 PROTOKINETIX, INC. (Name of

May 1, 2008 10QSB/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-QSB/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-QSB/A [ X ] Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 for the quarterly period ended September 30, 2004 or [ ] Transitional Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 for the transition period from to . Commission File No. 0-32917 PROTOKINETIX, INC. a develop

May 1, 2008 10QSB/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-QSB/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-QSB/A [ X ] Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 for the quarterly period ended June 30, 2004 or [ ] Transitional Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 for the transition period from to . Commission File No. 000-32917 PROTOKINETIX, INC. a developmen

April 30, 2008 10QSB/A

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-QSB/A

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-QSB/A [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2006 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355

April 30, 2008 10QSB/A

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-QSB/A

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-QSB/A [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2006 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026 (

April 30, 2008 10QSB/A

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-QSB/A

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-QSB/A [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2006 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026

April 15, 2008 10KSB

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-KSB [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2007 [X] TRANSITIONAL REPORT PURSUANT TO SECTI

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-KSB [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2007 [X] TRANSITIONAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 000-32917 PROTOKINETIX, INC. (Name of

March 28, 2008 NT 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING

NT 10-K 1 pktx12b25123107.htm PKTX 12B-25 (12-31-07) UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING (Check one): [X] Form 10-KSB [ ] Form 20-F [ ] Form 11-K [ ] Form 10-QSB [ ] Form N-SAR For Period Ended: December 31, 2007 [ ] Transition Report on Form 10-K [ ] Transition Report on Form 20-F [ ] Transition Report on Form 11-K [ ] Tr

March 26, 2008 CORRESP

United States Securities and Exchange Commission

United States Securities and Exchange Commission 100 F Street, N.E. Mail Stop 3561 Washington, D.C. 20549 Attention: Brian K. Bhandari March 26, 2008 RE: Registrant Name: Protokinetix, Inc. (the ?Company?) File No. 000-32917 Dear Mr. Bhandari: Further to our telephone conversation on March 18, 2008 and your letter dated March 17, 2008, the company has made the changes to all corporate filings iden

February 14, 2008 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* PROTOKINETIX INC COM (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Class of Se

SC 13G/A 1 c72216sc13gza.htm SCHEDULE 13G/A OMB APPROVAL OMB Number: 3235-0145 Expires: February 28, 2009 Estimated average burden hours per response...10.4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* PROTOKINETIX INC COM (Name of Issuer) Common Stock, par value $0.0000053 per share (Title of Clas

November 14, 2007 10QSB

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-QSB

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-QSB [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2007 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-335502

September 14, 2007 S-8 POS

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Registration No. 333-125844 Washington, D.C. 20549 POST EFFECTIVE AMENDMENT NO. 1 FORM S-8 REGISTRATION STATEMENT FILED PURSUANT TO THE SECURITIES ACT OF 1933 Date of Report: September 13, 2007 PROTOKI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Registration No. 333-125844 Washington, D.C. 20549 POST EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT FILED PURSUANT TO THE SECURITIES ACT OF 1933 Date of Report: September 13, 2007 PROTOKINETIX, INC. (Exact name of registrant as specified in its charter) Nevada 94-3355026 (State or other jurisdiction of incorporation or organization)

September 14, 2007 EX-4.1

PROTOKINETIX, INC. 2005 FIRST AMENDED STOCK INCENTIVE PLAN

PROTOKINETIX, INC. 2005 FIRST AMENDED STOCK INCENTIVE PLAN 1. Purpose of the Plan. The purpose of the 2005 First Amended Stock Incentive Plan (the ?Plan?) of ProtoKinetix, Inc., a Nevada corporation, (?Company?) is to provide the Company with a means of compensating selected key employees (including officers) and directors of and consultants to the Company (sometimes referred to hereinafter as ?Pa

August 21, 2007 10QSB/A

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-QSB/A

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-QSB/A [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2007 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026 (

August 20, 2007 10QSB

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-QSB

U. S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-QSB [X] QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2007 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-32917 PROTOKINETIX, INC. Nevada 94-3355026 (St

August 14, 2007 NT 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING (Check one): [ ] Form 10-KSB [ ] Form 20-F [ ] Form 11-K [X] Form 10-QSB [ ] Form N-SAR For Period Ended: June 30, 2007 [ ] Transition Report on Form 10-K [ ] Transition Report on Form 20-F [ ] Transition Report on Form 11-K [ ] Transition Report on Form 10-Q [ ] Transition Report on For

August 13, 2007 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) August 1, 2007 PROTOKINETIX, INC. (Exact name of registrant as specified in its charter) Nevada 000-32917 94-3355026 (State or other jurisdiction (Commission File Number) (IRS Employer of Incorporat

August 13, 2007 EX-99.2

August 1, 2007

August 1, 2007 To the Board of Directors of ProtoKinetix, Inc.: I want to extend my appreciation for the offer you have made in connection with my appointment to the position of member of the Board of Directors of ProtoKinetix, Inc. Please consider this letter my formal acceptance of this offer for appointment as a member of the Board of Directors. Best regards, /s/ Dr. Maximilien Arella Dr. Maxim

August 13, 2007 EX-99.3

August 1, 2007

August 1, 2007 To the Board of Directors of ProtoKinetix, Inc.: I want to extend my appreciation for the offer you have made in connection with my appointment to the position of President and Chief Executive Officer of ProtoKinetix, Inc. Please consider this letter my formal acceptance of this offer for appointment as President and Chief Executive Officer. Best regards, /s/ Ross L. Senior Ross L.

August 13, 2007 EX-99.1

August 1, 2007

August 1, 2007 To the Board of Directors of ProtoKinetix, Inc.: I, Mark L. Baum, Esq., hereby tender my resignation from the position of interim President and Director of ProtoKinetix, Inc. (the ?Company?), effective immediately. My resignation is not because of any disagreement with the Company on any matters relating to the Company?s operations, policies, disclosures and/or practices. Best regar

June 4, 2007 EX-99.1

May 28, 2007

May 28, 2007 To the Board of Directors of ProtoKinetix, Inc.: I, Dr. John Todd, hereby tender my resignation from the positions of President, Chief Executive Officer, Chief Financial Officer and Director of ProtoKinetix, Inc. (the ?Company?), effective immediately. My resignation is not because of any disagreement with the Company on any matters relating to the Company?s operations, policies, disc

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