SCIE / SpectraScience, Inc. - Pengajuan SECLaporan Tahunan, Pernyataan Proksi

SpectraScience, Inc.
US ˙ OTCPK

Mga Batayang Estadistika
CIK 727672
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to SpectraScience, Inc.
SEC Filings (Chronological Order)
Halaman ini menyediakan daftar lengkap dan kronologis dari Pengajuan SEC, tidak termasuk pengajuan kepemilikan yang kami sediakan di tempat lain.
November 27, 2017 DEF 14C

SCIE / SpectraSCIENCE, Inc. 14C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14C Information Statement Pursuant to Section 14(c) of the Securities Exchange Act of 1934 Check the appropriate box: [ ] Preliminary Information Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14c-5(d)(2)) [X] Definitive Information Statement SPECTRASCIENCE, INC. (Name of Registrant a

November 14, 2017 10-Q

SCIE / SpectraSCIENCE, Inc. 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2017 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or orga

November 7, 2017 PRE 14C

SCIE / SpectraSCIENCE, Inc. 14C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14C Information Statement Pursuant to Section 14(c) of the Securities Exchange Act of 1934 Check the appropriate box: [X] Preliminary Information Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14c-5(d)(2)) [ ] Definitive Information Statement SPECTRASCIENCE, INC. (Name of Registrant a

August 14, 2017 10-Q

SCIE / SpectraSCIENCE, Inc. 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2017 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or organizat

August 11, 2017 DEF 14C

SpectraSCIENCE 14C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14C Information Statement Pursuant to Section 14(c) of the Securities Exchange Act of 1934 Check the appropriate box: [ ] Preliminary Information Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14c-5(d)(2)) [X] Definitive Information Statement SPECTRASCIENCE, INC. (Name of Registrant a

July 31, 2017 PRE 14C

SpectraSCIENCE 14C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14C Information Statement Pursuant to Section 14(c) of the Securities Exchange Act of 1934 Check the appropriate box: [X] Preliminary Information Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14c-5(d)(2)) [ ] Definitive Information Statement SPECTRASCIENCE, INC. (Name of Registrant a

May 22, 2017 10-Q

SpectraSCIENCE (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2017 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction (I.R.S. Employer of incorpor

May 15, 2017 NT 10-Q

SpectraSCIENCE 0-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING SEC FILE NUMBER 33-24138-D CUSIP NUMBER 45247F 104 (Check One) [ ] Form 10-K [ ] Form 20-F [ ] Form 11-K [X] Form 10-Q [ ] Form N-SAR [ ] Form N-CSR For the Period Ended March 31, 2017 [ ] Transition Report on Form 10-K [ ] Transition Report on Form 20-F [ ] Transition Report on Form 11

May 8, 2017 DEF 14C

SpectraSCIENCE 14C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14C Information Statement Pursuant to Section 14(c) of the Securities Exchange Act of 1934 Check the appropriate box: [ ] Preliminary Information Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14c-5(d)(2)) [X] Definitive Information Statement SPECTRASCIENCE, INC. (Name of Registrant a

April 25, 2017 PRE 14C

SpectraSCIENCE 14C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14C Information Statement Pursuant to Section 14(c) of the Securities Exchange Act of 1934 Check the appropriate box: [X] Preliminary Information Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14c-5(d)(2)) [ ] Definitive Information Statement SPECTRASCIENCE, INC. (Name of Registrant a

March 31, 2017 10-K

SpectraSCIENCE (Annual Report)

10-K 1 form10-k.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K [X] ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: DECEMBER 31, 2016 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-13092 SPECTRASCIENCE, I

February 24, 2017 SC 13G

SCIE / SpectraSCIENCE, Inc. / GPL Ventures, LLC - SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* SPECTRASCIENCE, INC.. (Name of Issuer) Common Stock (Title of Class of Securities) 84760E301 (CUSIP Number) February 14, 2017 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Sc

January 23, 2017 DEF 14C

SpectraSCIENCE 14C

DEF 14C 1 def14c.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14C Information Statement Pursuant to Section 14(c) of the Securities Exchange Act of 1934 Check the appropriate box: [ ] Preliminary Information Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14c-5(d)(2)) [X] Definitive Information Statement SPECTRASCIENCE, INC.

January 18, 2017 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 18, 2017 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 000-13092 41-1448837 (State or Other Jurisdiction (Commission (I.R.S. Employer o

January 11, 2017 PRE 14C

SpectraSCIENCE 14C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14C Information Statement Pursuant to Section 14(c) of the Securities Exchange Act of 1934 Check the appropriate box: [X] Preliminary Information Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14c-5(d)(2)) [ ] Definitive Information Statement SPECTRASCIENCE, INC. (Name of Registrant a

November 14, 2016 EX-3.6

SPECTRASCIENCE, INC AMENDED BYLAWS ARTICLE I OFFICERS, CORPORATE SEAL AND SHAREHOLDER CONTROL AGREEMENT

Exhibit 3.6 SPECTRASCIENCE, INC AMENDED BYLAWS ARTICLE I OFFICERS, CORPORATE SEAL AND SHAREHOLDER CONTROL AGREEMENT SECTION 1.01. REGISTERED AND OTHER OFFICES. The registered office of the corporation in Minnesota shall be that set forth in the Articles of Incorporation or statement of the Board of Directors filed with the Secretary of State of Minnesota changing the registered office in the manne

November 14, 2016 EX-3.3

AMENDMENT TO AMENDED AND RESTATED ARTICLES OF INCORPORATION OF SPECTRASCIENCE, INC.

EX-3.3 4 ex3-3.htm Exhibit 3.3 AMENDMENT TO AMENDED AND RESTATED ARTICLES OF INCORPORATION OF SPECTRASCIENCE, INC. SpectraScience, Inc., a corporation organized and existing under the laws of the State of Minnesota (the “Company”), hereby certifies as follows: The members of the Board of Directors have adopted a resolution amending Section 2.01 of the Amended and Restated Articles of Incorporation

November 14, 2016 EX-3.5

AMENDMENT TO AMENDED AND RESTATED ARTICLES OF INCORPORATION OF SPECTRASCIENCE, INC.

EX-3.5 6 ex3-5.htm Exhibit 3.5 AMENDMENT TO AMENDED AND RESTATED ARTICLES OF INCORPORATION OF SPECTRASCIENCE, INC. SpectraScience, Inc., a corporation organized and existing under the laws of the State of Minnesota (the “Company”), hereby certifies as follows: The members of the Board of Directors have adopted a resolution amending Section 2.01 of the Amended and Restated Articles of Incorporation

November 14, 2016 EX-3.7

CERTIFICATE OF CREATION OF SERIES A PREFERRED STOCK SPECTRASCIENCE, INC.

Exhibit 3.7 CERTIFICATE OF CREATION OF SERIES A PREFERRED STOCK OF SPECTRASCIENCE, INC. I, James Hitchin, Chief Executive Officer of SpectraScience, Inc. a Minnesota corporation (the ?Company?), do hereby certify that on June 12, 2007, under the authority of Article II, Section 2.01 of the Company?s Amended and Restated Articles of Incorporation, the Board of Directors of the Company unanimously a

November 14, 2016 EX-3.4

AMENDMENT TO AMENDED AND RESTATED ARTICLES OF INCORPORATION OF SPECTRASCIENCE, INC.

Exhibit 3.4 AMENDMENT TO AMENDED AND RESTATED ARTICLES OF INCORPORATION OF SPECTRASCIENCE, INC. SpectraScience, Inc., a corporation organized and existing under the laws of the State of Minnesota (the ?Company?), hereby certifies as follows: The members of the Board of Directors have adopted a resolution amending Section 2.01 of the Amended and Restated Articles of Incorporation of the Company, an

November 14, 2016 EX-3.8

CERTIFICATE OF DESIGNATION OF RIGHTS AND PREFERENCES OF SERIES B PREFERRED STOCK OF SPECTRASCIENCE, INC. (PURSUANT TO MINNESOTA STATUTES, SECTION 302A.401, SUBD. 3(B))

EX-3.8 9 ex3-8.htm Exhibit 3.8 CERTIFICATE OF DESIGNATION OF RIGHTS AND PREFERENCES OF SERIES B PREFERRED STOCK OF SPECTRASCIENCE, INC. (PURSUANT TO MINNESOTA STATUTES, SECTION 302A.401, SUBD. 3(B)) The undersigned, being the Secretary of SpectraScience, Inc., a corporation organized and existing under the laws of the State of Minnesota (the “Company”), in accordance with the provisions of Minneso

November 14, 2016 10-Q

SpectraSCIENCE (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2016 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction (I.R.S. Employer of inco

November 14, 2016 EX-3.2

CERTIFICATE OF AMENDMENT TO ARTICLES OF INCORPORATION OF SPECTRASCIENCE, INC.

Exhibit 3.2 CERTIFICATE OF AMENDMENT TO ARTICLES OF INCORPORATION OF SPECTRASCIENCE, INC. The undersigned, being the Chief Executive Officer of SpectraScience, Inc., a Minnesota corporation (the ?Corporation?), in accordance with the Minnesota Business Corporation Act, does hereby certify that the Board of Directors adopted the following resolutions effective as of September 21, 2009: AMENDMENT TO

November 14, 2016 EX-3.9

CERTIFICATE OF DESIGNATION OF RIGHTS AND PREFERENCES OF SERIES C PREFERRED STOCK OF SPECTRASCIENCE, INC. (PURSUANT TO MINNESOTA STATUTES, SECTION 302A.401, SUBD. 3(B))

Exhibit 3.9 CERTIFICATE OF DESIGNATION OF RIGHTS AND PREFERENCES OF SERIES C PREFERRED STOCK OF SPECTRASCIENCE, INC. (PURSUANT TO MINNESOTA STATUTES, SECTION 302A.401, SUBD. 3(B)) The undersigned, being the Secretary of SpectraScience, Inc., a corporation organized and existing under the laws of the State of Minnesota (the ?Company?), in accordance with the provisions of Minnesota Statutes, Sectio

November 14, 2016 EX-3.10

CERTIFICATE OF DESIGNATIONS, PREFERENCES AND RIGHTS OF SERIES AA, NON-TRANSFERRABLE, SUPER VOTING, PREFERRED STOCK OF SPECTRASCIENCE, INC.

EX-3.10 11 ex3-10.htm Exhibit 3.10 CERTIFICATE OF DESIGNATIONS, PREFERENCES AND RIGHTS OF SERIES AA, NON-TRANSFERRABLE, SUPER VOTING, PREFERRED STOCK OF SPECTRASCIENCE, INC. SpectraScience, Inc., a Minnesota corporation (the “Corporation”), DOES HEREBY CERTIFY: Pursuant to the authority expressly granted and vested in the Board of Directors of the Corporation the following resolutions were adopted

November 14, 2016 EX-3.1

AMENDED AND RESTATED ARTICLES OF INCORPORATION OF SPECTRASCIENCE, INC.

Exhibit 3.1 AMENDED AND RESTATED ARTICLES OF INCORPORATION OF SPECTRASCIENCE, INC. The Articles of Incorporation of SpectraScience, Inc., as amended, are hereby amended and restated in their entirety to read as follows: ARTICLE I. NAME AND REGISTERED OFFICE 1.1 Name. The name of this Corporation is SpectraScience, Inc. 1.2 Registered Office. The location and post office address of the registered o

November 14, 2016 EX-3.11

CERTIFICATE OF DESIGNATIONS, PREFERENCES AND RIGHTS OF SERIES A PREFERRED STOCK; SERIES B PREFERRED STOCK; SERIES C PREFERRED STOCK; SERIES AA, NON-TRANSFERRABLE, SUPER VOTING, PREFERRED STOCK; AND UNDESIGNATED STOCK OF SPECTRASCIENCE, INC.

EX-3.11 12 ex3-11.htm Exhibit 3.11 CERTIFICATE OF DESIGNATIONS, PREFERENCES AND RIGHTS OF SERIES A PREFERRED STOCK; SERIES B PREFERRED STOCK; SERIES C PREFERRED STOCK; SERIES AA, NON-TRANSFERRABLE, SUPER VOTING, PREFERRED STOCK; AND UNDESIGNATED STOCK OF SPECTRASCIENCE, INC. SpectraScience, Inc., a Minnesota corporation (the “Corporation”), DOES HEREBY CERTIFY: Pursuant to the authority expressly

October 3, 2016 DEFR14C

SpectraSCIENCE 14C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14C Amendment No. 1 Information Statement Pursuant to Section 14(c) of the Securities Exchange Act of 1934 Check the appropriate box: [ ] Preliminary Information Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14c-5(d)(2)) [X] Definitive Information Statement SPECTRASCIENCE, INC. (Name

September 22, 2016 EX-3.6

CERTIFICATE OF DESIGNATIONS, PREFERENCES AND RIGHTS OF SERIES AA, NON-TRANSFERRABLE, SUPER VOTING, PREFERRED STOCK OF SPECTRASCIENCE, INC.

Exhibit 3.6 CERTIFICATE OF DESIGNATIONS, PREFERENCES AND RIGHTS OF SERIES AA, NON-TRANSFERRABLE, SUPER VOTING, PREFERRED STOCK OF SPECTRASCIENCE, INC. SpectraScience, Inc., a Minnesota corporation (the ?Corporation?), DOES HEREBY CERTIFY: Pursuant to the authority expressly granted and vested in the Board of Directors of the Corporation the following resolutions were adopted on April 15, 2016: WHE

September 22, 2016 8-K

Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 25, 2014 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 000-13092 41-1448837 (State or Other Jurisdiction of Incorporation) (Commission F

September 22, 2016 EX-3.5

AMENDMENT TO AMENDED AND RESTATED ARTICLES OF INCORPORATION OF SPECTRASCIENCE, INC.

Exhibit 3.5 AMENDMENT TO AMENDED AND RESTATED ARTICLES OF INCORPORATION OF SPECTRASCIENCE, INC. SpectraScience, Inc., a corporation organized and existing under the laws of the State of Minnesota (the ?Company?), hereby certifies as follows: The members of the Board of Directors have adopted a resolution amending Section 2.01 of the Amended and Restated Articles of Incorporation of the Company, an

September 22, 2016 CORRESP

SpectraSCIENCE ESP

September 21, 2016 Mr. Tom Jones United States Securities and Exchange Commission Washington, D.C. 20549 Re: SpectraScience, Inc. Amendment No. 1 to Preliminary Information Statement on Schedule 14C Filed September 13, 2016 File No. 000-13092 Dear Mr. Jones: Thank you for the comment and questions raised in your letter of September 19, 2016, regarding the referenced filing. In order to expedite yo

September 13, 2016 8-K

Changes in Control of Registrant, Material Modification to Rights of Security Holders, Unregistered Sales of Equity Securities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 19, 2016 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 000-13092 41-1448837 (State or Other Jurisdiction of Incorporation) (Commission Fi

September 13, 2016 PRER14C

SpectraSCIENCE 14C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14C Amendment No. 1 Information Statement Pursuant to Section 14(c) of the Securities Exchange Act of 1934 Check the appropriate box: [X] Preliminary Information Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14c-5(d)(2)) [ ] Definitive Information Statement SPECTRASCIENCE, INC. (Name

September 12, 2016 CORRESP

SpectraSCIENCE ESP

September 12, 2016 Mr. Tom Jones United States Securities and Exchange Commission Washington, D.C. 20549 Re: SpectraScience, Inc. (the ?Company?) Preliminary Information Statement on Schedule 14C Filed August 16, 2016 File No. 000-13092 Dear Mr. Jones: Thank you for the comments and questions raised in your letter of August 31, 2016, regarding the referenced filing. In order to expedite your revie

August 29, 2016 DEF 14C

SpectraSCIENCE 14C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14C Information Statement Pursuant to Section 14(c) of the Securities Exchange Act of 1934 Check the appropriate box: [ ] Preliminary Information Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14c-5(d)(2)) [X] Definitive Information Statement SPECTRASCIENCE, INC. (Name of Registrant a

August 19, 2016 EX-99.(A)(1)(A)

OFFER TO EXCHANGE WARRANTS TO PURCHASE COMMON STOCK ISSUED BETWEEN JANUARY 27, 2012 – MARCH 14, 2016 THE OFFER AND WITHDRAWAL RIGHTS WILL EXPIRE AT 11:59 P.M. (EASTERN TIME) ON NOVEMBER __, 2016, UNLESS THE OFFER IS EXTENDED THE DATE OF THIS OFFER DO

EX-99.(A)(1)(A) 2 ex-a1a.htm Exhibit (a)(1)(A) NEITHER THE SECURITIES AND EXCHANGE COMMISSION NOR ANY STATE SECURITIES COMMISSION HAS APPROVED OR DISAPPROVED OF THIS TRANSACTION OR PASSED UPON THE MERITS OR FAIRNESS OF SUCH TRANSACTION OR PASSED UPON THE ADEQUACY OR ACCURACY OF THE INFORMATION CONTAINED IN THIS DOCUMENT. ANY REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE. OFFER TO EXCHANGE W

August 19, 2016 EX-99.(A)(1)(B)

SPECTRASCIENCE, INC. OFFER TO EXCHANGE WARRANTS TO PURCHASE COMMON STOCK ISSUED BETWEEN JANUARY 27, 2012 – MARCH 14, 2016 ELECTION FORM INSTRUCTIONS

Exhibit (a)(1)(B) SPECTRASCIENCE, INC. OFFER TO EXCHANGE WARRANTS TO PURCHASE COMMON STOCK ISSUED BETWEEN JANUARY 27, 2012 ? MARCH 14, 2016 ELECTION FORM INSTRUCTIONS August , 2016 Dear Eligible Warrants Holder: All terms used in this Election Form but not defined herein have the meanings given to them in the ?Offer to Exchange? dated August , 2016 (the ?Offering Memorandum?). To participate in th

August 19, 2016 EX-99.(A)(1)(C)

SPECTRASCIENCE, INC. OFFER TO EXCHANGE WARRANTS TO PURCHASE COMMON STOCK ISSUED BETWEEN JANUARY 27, 2012 – MARCH 31, 2016 WITHDRAWAL FORM INSTRUCTIONS

Exhibit (a)(1)(C) SPECTRASCIENCE, INC. OFFER TO EXCHANGE WARRANTS TO PURCHASE COMMON STOCK ISSUED BETWEEN JANUARY 27, 2012 ? MARCH 31, 2016 WITHDRAWAL FORM INSTRUCTIONS August , 2016 Dear Eligible Warrant Holder: All terms used in this Withdrawal Form but not defined herein have the meanings given to them in the ?Offer to Exchange? dated August , 2016 (the ?Offering Memorandum?). If the Company re

August 19, 2016 SC TO-I

SpectraSCIENCE O-I

SC TO-I 1 formscto-i.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE TO (Rule 14d-100) TENDER OFFER STATEMENT UNDER SECTION 14(d)(1) OR 13(e)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 SpectraScience, Inc. (Name of Subject Company (Issuer) and Name of Filing Person (Offeror)) Common Stock, Par Value $0.01 per share (Title of Class of Securities) 84760E (CUSIP Nu

August 19, 2016 EX-99.(A)(1)(D)

[Letterhead of SpectraScience, Inc.]

EX-99.(A)(1)(D) 5 ex-a1d.htm Exhibit (a)(1)(D) [Letterhead of SpectraScience, Inc.] August , 2016 To the Holders of Eligible Warrant(s): This letter is to inform you, as a holder of Warrant(s) to Purchase Common Stock issued between January 27, 2012 and March 14, 2016 (the “Eligible Warrant(s)”), that we are offering to exchange your Eligible Warrant(s) for: (i) the issuance of restricted shares o

August 16, 2016 PRE 14C

SpectraSCIENCE 14C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14C Information Statement Pursuant to Section 14(c) of the Securities Exchange Act of 1934 Check the appropriate box: [X] Preliminary Information Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14c-5(d)(2)) [ ] Definitive Information Statement SPECTRASCIENCE, INC. (Name of Registrant a

August 16, 2016 PRE 14C

SpectraSCIENCE 14C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14C Information Statement Pursuant to Section 14(c) of the Securities Exchange Act of 1934 Check the appropriate box: [X] Preliminary Information Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14c-5(d)(2)) [ ] Definitive Information Statement SPECTRASCIENCE, INC. (Name of Registrant a

August 15, 2016 10-Q

SpectraSCIENCE (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2016 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or organizat

August 15, 2016 10-Q

SpectraSCIENCE (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2016 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or organizat

May 20, 2016 10-Q

SpectraSCIENCE FORM 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2016 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction (I.R.S. Employer Identificat

May 16, 2016 NT 10-Q

SpectraSCIENCE NT 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING SEC FILE NUMBER 33-24138-D CUSIP NUMBER 45247F 104 (Check One) [ ] Form 10-K [ ] Form 20-F [ ] Form 11-K [X ] Form 10-Q [ ] Form N-SAR [ ] Form N-CSR For the Period Ended March 31, 2016 [ ] Transition Report on Form 10-K [ ] Transition Report on Form 20-F [ ] Transition Report on Form 1

March 30, 2016 10-K

SpectraSCIENCE 10-K (Annual Report)

10-K 1 s10273710k.htm 10-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K x ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: DECEMBER 31, 2015 ¨ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-13092 SPECTRASCIENCE

January 5, 2016 8-K

Changes in Registrant's Certifying Accountant

8-K 1 s1024238k.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 4 , 2016 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 000-13092 41-1448837 (State or Other Jurisdiction of Inc

January 5, 2016 EX-16.1

January 4, 2016

Exhibit 16.1 January 4, 2016 U.S. Securities and Exchange Commission 100 F. Street Washington, DC 20549 ? 7561 Ladies and Gentlemen: Re: SpectraScience, Inc. Commission File No. 000-55097 We have read the statements of SpectraScience, Inc. pertaining to our firm included in Item 4.01 of the Form 8-K dated January 4, 2016 and are in agreement with the statements contained in that document pertainin

November 16, 2015 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2015 Commission file number 0-13092

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2015 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or orga

November 16, 2015 SC 13G

SCIE / SpectraSCIENCE, Inc. / VIS VIRES GROUP, INC. - SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (AMENDMENT NO. )* SPECTRASCIENCE, INC. (Name of issuer) Common Stock, $0.01 value per share (Title of class of securities) 84760E301 (CUSIP number) November 16, 2015 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pur

October 22, 2015 CORRESP

SpectraSCIENCE ESP

October 22, 2015 Mr. Martin James United States Securities and Exchange Commission Washington, D.C. 20549 Re: SpectraScience, Inc. Form 10-K for the year ended December 31, 2014 Forms 10-Q for the quarters ended March 31, 2015 and June 30, 2015 File Number: 000-13092 Dear Mr. James: We are responding to the Staff?s comments and questions raised in your letter of October 1, 2015, regarding the refe

August 14, 2015 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2015 Commission file number 0-13092 SPECT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2015 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or organizat

May 14, 2015 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2015 Commission file number 0-13092 SPEC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2015 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or organiza

April 6, 2015 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 6, 2015 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 000-13092 41-1448837 (State or Other Jurisdiction of Incorporation) (Commission Fil

March 20, 2015 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K S ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: DECEMBER 31, 2014 £ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-13092 SPECTRASCIENCE, INC. (Exact name of regis

December 3, 2014 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 1, 2014 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 000-13092 41-1448837 (State or Other Jurisdiction of Incorporation) (Commission

November 12, 2014 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2014 Commission file number 0-13092

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2014 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or orga

August 26, 2014 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 21, 2014 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 000-13092 41-1448837 (State or Other Jurisdiction of Incorporation) (Commission F

August 14, 2014 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2014 Commission file number 0-13092 SPECT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2014 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction (I.R.S. Employer Identificati

July 21, 2014 DEF 14A

SCIE / SpectraSCIENCE, Inc. DEF 14A - - DEFINITIVE PROXY STATEMENT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) x Definitive Proxy State

July 9, 2014 PRE 14A

SCIE / SpectraSCIENCE, Inc. PRE 14A - - PRELIMINARY PROXY STATEMENT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: x Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

June 30, 2014 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2014 Commission file number 0-13092 SPEC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2014 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or organiza

June 27, 2014 EX-10.14

EMPLOYMENT AGREEMENT

Exhibit 10.14 EMPLOYMENT AGREEMENT THIS EMPLOYMENT AGREEMENT (this “Agreement”) is entered into by and between SpectraScience, Inc., a Minnesota corporation (the “Company”), and Michael Oliver (“Executive”), effective January 1, 2013 (the “Effective Date”). RECITALS WHEREAS, Executive currently is employed by SpectraScience as its President and Chief Executive Officer. WHEREAS, the Company wishes

June 27, 2014 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K x ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: DECEMBER 31, 2013 ¨ TRANSITION REPORT UNDER SECTION 13 OR 15

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K x ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: DECEMBER 31, 2013 ¨ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-13092 SPECTRASCIENCE, INC. (Exact name of regis

April 18, 2014 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2013 Commission file number 0-13092

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2013 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or orga

March 28, 2014 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2013 Commission file number 0-13092 SPECT

10-Q 1 v36142510q.htm FORM 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2013 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdicti

March 28, 2014 EX-10.2

5% ORIGINAL ISSUE DISCOUNT UNSECURED CONVERTIBLE DEBENTURE DUE SEPTEMBER __, 2014 (1)

Exhibit 10.2 NEITHER THIS SECURITY NOR THE SECURITIES INTO WHICH THIS SECURITY IS CONVERTIBLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD OR OTHERWISE TRANSFERRED, PLEDGED OR

March 28, 2014 EX-10.1

SUBSCRIPTION AGREEMENT

Exhibit 10.1 SUBSCRIPTION AGREEMENT This SUBSCRIPTION AGREEMENT (this “Agreement”) is made as of the last date set forth on the signature page hereof between SpectraScience, Inc., a Minnesota corporation (the “Company”), and the undersigned (the “Subscriber”). WITNESSETH: WHEREAS, the Company is conducting a private offering (the “Offering”) of 5% original issue discount unsecured convertible debe

March 28, 2014 EX-10.3

COMMON STOCK PURCHASE WARRANT SPECTRASCIENCE, Inc.

Exhibit 10.3 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD OR OTHERWISE TRANSFERRED, PLEDGED OR H

February 26, 2014 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 11, 2014 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Numbe

February 7, 2014 EX-16.1

February 7, 2014

February 7, 2014 Securities and Exchange Commission Washington, D.C. 20549 Commissioners: We have read SpectraScience, Inc.'s statements included under Item 4.01 of its Form 8-K filed on February 7, 2014 and we agree with such statements concerning our firm. McGladrey LLP

February 7, 2014 8-K

Financial Statements and Exhibits, Changes in Registrant's Certifying Accountant - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 3, 2014 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 000-13092 41-1448837 (State or Other Jurisdiction of Incorporation) (Commission

December 26, 2013 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 20, 2013 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Numbe

November 8, 2013 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 25, 2013 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number

October 4, 2013 EX-99.1

SpectraScience Appoints Lowell Giffhorn to be Chief Financial Officer

EX-99.1 3 v356571ex99-1.htm EXHIBIT 99.1 SpectraScience Appoints Lowell Giffhorn to be Chief Financial Officer SAN DIEGO, October 4, 2013 (Globe Newswire) – SpectraScience, Inc. (OTCQB:SCIE), a San Diego-based medical device company, today announced that its board of directors has appointed Lowell Giffhorn as the Company’s new Chief Financial Officer. Michael Oliver, President and Chief Executive

October 4, 2013 EX-10.1

CONSULTING AGREEMENT

CONSULTING AGREEMENT This Consulting Agreement (“Agreement”) is between SpectraScience, Inc.

October 4, 2013 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events - FORM 8-K

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 30, 2013 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 41-1448837

September 25, 2013 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 3, 2013 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Numbe

September 25, 2013 EX-10.1

EX-10.1

EX-10.1 2 v355748ex10-1.htm EXHIBIT 10.1

July 16, 2013 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 12, 2013 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 4

July 5, 2013 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 3, 2013 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 41

June 14, 2013 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 14, 2013 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 4

May 20, 2013 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2013 Commission file number 0-13092 SPEC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2013 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or organiza

May 15, 2013 NT 10-Q

- NT 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 SEC FILE NUMBER 000-13092 NOTIFICATION OF LATE FILING CUSIP NUMBER 84760E301 (Check one): ¨ Form 10-K ¨ Form 20-F ¨ Form 11-K x Form 10-Q ¨ Form 10-D ¨ Form N-SAR ¨ Form N-CSR For Period Ended: March 31, 2013 o Transition Report on Form 10-K o Transition Report on Form 20-F o Transition Report on Form 11-K o Transi

April 18, 2013 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K x ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: DECEMBER 31, 2012 ¨ TRANSITION REPORT UNDER SECTION 13 OR 15

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K x ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: DECEMBER 31, 2012 ¨ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-13092 SPECTRASCIENCE, INC. (Exact name of regis

April 5, 2013 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 5, 2013 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 000-13092 41-1448837 (State of other jurisdiction of (Commission File Number) (I.R.

April 5, 2013 EX-99.1

Good morning, ladies and gentlemen, and welcome to the SpectraScience Inc. Business Update Conference Call. [Operator Instructions] As a reminder, this conference is being recorded for replay purposes. I would now like to turn the presentation over t

Exhibit 99.1 Operator: Good morning, ladies and gentlemen, and welcome to the SpectraScience Inc. Business Update Conference Call. [Operator Instructions] As a reminder, this conference is being recorded for replay purposes. I would now like to turn the presentation over to your host for today's call, Eric Weiner from Stonegate. Eric Weiner: Thank you and good morning. Welcome to SpectraScience’s

April 1, 2013 NT 10-K

- NT 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING SEC FILE NUMBER CUSIP NUMBER (Check One): x Form 10-K ¨ Form 20-F ¨ Form 10-Q ¨ Form 10-D ¨ Form N-SAR For Period Ended: December 31, 2012 ¨ Transition Report on Form 10-K ¨ Transition Report on Form 20-F ¨ Transition Report on Form 11-K ¨ Transition Report on Form 10-Q ¨ Transition Repo

March 25, 2013 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 22, 2013 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number)

March 18, 2013 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - CURRENT REPORT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 12, 2013 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number)

February 28, 2013 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 22, 2013 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Numbe

February 12, 2013 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 6, 2013 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number

December 31, 2012 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 31, 2012 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Numbe

December 10, 2012 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 10, 2012 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Numbe

November 15, 2012 EX-4.2

COMMON STOCK PURCHASE WARRANT SPECTRASCIENCE, Inc.

EXHIBIT 4.2 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD OR OTHERWISE TRANSFERRED, PLEDGED OR HY

November 15, 2012 10-Q/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q/A (Amendment No. 1) QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2012 Commission

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q/A (Amendment No. 1) QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2012 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of i

November 15, 2012 EX-10.1

SUBSCRIPTION AGREEMENT

EXHIBIT 10.1 SUBSCRIPTION AGREEMENT This SUBSCRIPTION AGREEMENT (this “Agreement”) is made as of the last date set forth on the signature page hereof between SpectraScience, Inc., a Minnesota corporation (the “Company”), and the undersigned (the “Subscriber”). W I T N E S S E T H: WHEREAS, the Company is conducting a private offering (the “Offering”) for which Laidlaw & Company (UK) Ltd. is acting

November 15, 2012 EX-4.1

5% ORIGINAL ISSUE DISCOUNT UNSECURED CONVERTIBLE DEBENTURE DUE __________, 2013

EXHIBIT 4.1 NEITHER THIS SECURITY NOR THE SECURITIES INTO WHICH THIS SECURITY IS CONVERTIBLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD OR OTHERWISE TRANSFERRED, PLEDGED OR H

November 15, 2012 NT 10-Q

- NT 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 SEC FILE NUMBER 000-13092 NOTIFICATION OF LATE FILING CUSIP NUMBER 84760E301 (Check one): ¨ Form 10-K ¨ Form 20-F ¨ Form 11-K x Form 10-Q ¨ Form 10-D ¨ Form N-SAR ¨ Form N-CSR For Period Ended: September 30, 2012 o Transition Report on Form 10-K o Transition Report on Form 20-F o Transition Report on Form 11-K o Tr

November 15, 2012 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2012 Commission file number 0-13092

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2012 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or orga

November 13, 2012 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 9, 2012 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number

October 22, 2012 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 19, 2012 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number

October 15, 2012 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 12, 2012 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number

September 20, 2012 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 19, 2012 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Numb

September 13, 2012 10-Q/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q/A QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2012 Commission file number 0-13092 SPE

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q/A QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2012 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or organiz

August 29, 2012 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 28, 2012 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number)

August 14, 2012 EX-10.1

PENTAX EUROPE DISTRIBUTOR AGREEMENT

EXHIBIT 10.1 PENTAX EUROPE DISTRIBUTOR AGREEMENT THIS PENTAX EUROPE DISTRIBUTOR AGREEMENT (this “Agreement”), effective this 15th day of June 2012 (the “Effective Date”), by and between SpectraScience, Inc., a Minnesota corporation with offices at 11568-11 Sorrento Valley Road, San Diego, California USA 92121 (“SpectraScience”), and PENTAX Europe GmbH organized under the laws of Germany, with offi

August 14, 2012 EX-3.1

AMENDMENT TO AMENDED AND RESTATED ARTICLES OF INCORPORATION OF SPECTRASCIENCE, INC.

EX-3.1 2 v321129ex3-1.htm EXHIBIT 3.1 Exhibit 3.1 AMENDMENT TO AMENDED AND RESTATED ARTICLES OF INCORPORATION OF SPECTRASCIENCE, INC. SpectraScience, Inc., a corporation organized and existing under the laws of the State of Minnesota (the “Company”), hereby certifies as follows: The members of the Board of Directors have adopted a resolution amending Section 2.01 of the Amended and Restated Articl

August 14, 2012 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2012 Commission file number 0-13092 SPECT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2012 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or organizat

July 13, 2012 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 12, 2012 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 000-13092 41-1448837 (State of other jurisdiction of (Commission File Number) (I.R.

July 13, 2012 EX-99.1

1 July 13, 2012

EX-99.1 2 v318498ex99-1.htm EXHIBIT 99.1 1 July 13, 2012 2 This presentation contains statements of a forward - looking nature which represent our management's beliefs and assumptions concerning future events . When used in this presentation, the words “believe,” “expect,” and similar expressions are intended to identify forward - looking statements, including statements regarding revenue, distrib

July 13, 2012 EX-99.2

1 July 2012

1 July 2012 2 This presentation contains statements of a forward - looking nature which represent our management's beliefs and assumptions concerning future events .

June 21, 2012 EX-99.1

SpectraScience Signs Europe and Middle East Distribution Agreement with PENTAX for the WavSTAT Optical Biopsy System

EX-99.1 2 v316466ex99-1.htm EXHIBIT 99.1 EXHIBIT 99.1 SpectraScience Signs Europe and Middle East Distribution Agreement with PENTAX for the WavSTAT Optical Biopsy System SAN DIEGO, June 18, 2012 (MARKETWIRE) – SpectraScience, Inc. (OTCQB: SCIE), a San Diego based medical device company, has signed an exclusive five-year agreement with PENTAX Europe GmbH to distribute its WavSTAT Optical Biopsy Sy

June 21, 2012 8-K

- FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 15, 2012 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 4

June 14, 2012 DEF 14A

- FORM DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) x Definitive Proxy State

June 4, 2012 PRE 14A

- PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: x Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

May 16, 2012 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2012 Commission file number 0-13092 SPEC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2012 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or organiza

April 2, 2012 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 30, 2012 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number)

March 30, 2012 EX-3.4

CERTIFICATE OF REDESIGNATION OF SERIES C PREFERRED STOCK

EX-3.4 2 v307140ex3-4.htm EXHIBIT 3.4 Exhibit 3.4 CERTIFICATE OF REDESIGNATION OF SERIES C PREFERRED STOCK I, Jim Dorst, Chief Financial Officer of SpectraScience, Inc., a Minnesota corporation (the “Company”), do hereby certify that on January 13, 2012, under the authority of Article II, Section 2.01 of the Company’s Amended and Restated Articles of Incorporation, the Board of Directors of the Co

March 30, 2012 EX-10.10

FORM OF SUBSCRIPTION AGREEMENT

Exhibit 10.10 FORM OF SUBSCRIPTION AGREEMENT This SUBSCRIPTION AGREEMENT (this “Agreement”) is made as of the last date set forth on the signature page hereof between SpectraScience, Inc., a Minnesota corporation (the “Company”), and the undersigned (the “Subscriber”). WITNESSETH: WHEREAS, the Company is conducting a private offering (the “Offering”)for which Laidlaw & Company (UK) Ltd. is acting

March 30, 2012 EX-21

SUBSIDIARIES

Exhibit 21 SUBSIDIARIES LUMA Imaging Corporation, a Delaware Corporation SpectraScience International, Inc., a Minnesota Corporation

March 30, 2012 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K x ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: DECEMBER 31, 2011 ¨ TRANSITION REPORT UNDER SECTION 13 OR 15

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K x ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: DECEMBER 31, 2011 ¨ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-13092 SPECTRASCIENCE, INC. (Exact name of regis

March 16, 2012 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 15, 2012 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number)

February 23, 2012 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 22, 2012 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Numbe

January 30, 2012 EX-4.2

COMMON STOCK PURCHASE WARRANT SPECTRASCIENCE, Inc.

NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD OR OTHERWISE TRANSFERRED, PLEDGED OR HYPOTHECATED E

January 30, 2012 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant -

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 27, 2012 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number

January 30, 2012 EX-4.1

5% ORIGINAL ISSUE DISCOUNT UNSECURED CONVERTIBLE DEBENTURE DUE JULY 27, 2012

EX-4.1 2 v300748ex4-1.htm NEITHER THIS SECURITY NOR THE SECURITIES INTO WHICH THIS SECURITY IS CONVERTIBLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD OR OTHERWISE TRANSFERRED

November 14, 2011 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2011 Commission file number 0-13092

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2011 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or orga

September 15, 2011 EX-99.1

EX-99.1

September 15, 2011 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 13, 2011 SPECTRASCIENCE

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 13, 2011 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Numb

September 13, 2011 10-Q/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q (Amendment No. 1) QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2011 Commission file nu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q (Amendment No. 1) QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2011 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorpor

August 15, 2011 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2011 Commission file number 0-13092 SPECT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2011 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or organizat

July 18, 2011 EX-99.1

EX-99.1

July 18, 2011 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 15, 2011 SPECTRASCIENCE, INC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 15, 2011 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 000-13092 41-1448837 (State of other jurisdiction of (Commission File Number) (I.R.

June 22, 2011 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 21, 2011 SPECTRASCIENCE, INC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 21, 2011 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 000-13092 41-1448837 (State of other jurisdiction of (Commission File Number) (I.R.

June 22, 2011 EX-99.1

EX-99.1

June 14, 2011 8-K

Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 13, 2011 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 4

June 14, 2011 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) x Definitive Proxy State

June 14, 2011 EX-99.1

·

Exhibit 99.1 Dear Shareholders, This past year was transformative for SpectraScience, culminating with our Board of Directors’ strategic decision to move our business in a new direction. As you are aware, 2010 was not without its challenges. On a macro level, healthcare service providers faced tighter budgets amidst continued uncertainty in the global healthcare market. These challenges were exace

May 16, 2011 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2011 Commission file number 0-13092 SPEC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2011 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or organiza

March 31, 2011 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K x ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: DECEMBER 31, 2010 o TRANSITION REPORT UNDER SECTION 13 OR 15

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K x ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: DECEMBER 31, 2010 o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-13092 SPECTRASCIENCE, INC. (Exact name of regis

March 31, 2011 EX-10.7

November 24, 2010

Exhibit 10.7 November 24, 2010 Michael P. Oliver San Diego, California 92127 Dear Michael: I am pleased to offer you a position with SpectraScience, Inc. (the “Company”), as its Chief Executive Officer. If you decide to join us, you will receive an annual salary of $225,000, which will be paid weekly in accordance with the Company’s normal payroll procedures. In addition you will be paid cash bonu

March 1, 2011 EX-10.1

SPECTRASCIENCE, INC. 2011 EQUITY INCENTIVE PLAN SECTION 1.

SPECTRASCIENCE, INC. 2011 EQUITY INCENTIVE PLAN SECTION 1. DEFINITIONS As used herein, the following terms shall have the meanings indicated below: (a) “Administrator” shall mean the Board of Directors of the Company, or one or more Committees appointed by the Board, as the case may be. (b) “Affiliate(s)” shall mean a Parent or Subsidiary of the Company. (c) “Award” shall mean any grant of an Opti

March 1, 2011 EX-24

EX-24

POWER OF ATTORNEY For Executing Forms 3, 4 and 5 The undersigned hereby constitutes and appoints James Dorst, Ryan C.

March 1, 2011 EX-10.2

NONQUALIFIED STOCK OPTION AGREEMENT SPECTRASCIENCE, INC. 2011 EQUITY INCENTIVE PLAN

NONQUALIFIED STOCK OPTION AGREEMENT SPECTRASCIENCE, INC. 2011 EQUITY INCENTIVE PLAN THIS AGREEMENT, made effective as of this day of , 20, by and between SpectraScience, Inc., a Minnesota corporation (the “Company”), and (“Participant”). WITNESSETH: WHEREAS, Participant on the date hereof is a key employee, officer, director of or consultant or advisor to the Company or one of its Subsidiaries; an

March 1, 2011 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 24, 2011 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 000-13092 41-1448837 (State of other jurisdiction of incorporation) (Commission

February 15, 2011 EX-24

EX-24

POWER OF ATTORNEY For Executing Forms 4 and 5 The undersigned hereby constitutes and appoints James Dorst, Ryan C.

February 10, 2011 CORRESP

11568-11 Sorrento Valley Road San Diego, California 92121

11568-11 Sorrento Valley Road San Diego, California 92121 February 10, 2011 VIA EDGAR AND FEDEX Ms.

January 27, 2011 CORRESP

* * * * *

11568-11 Sorrento Valley Road San Diego, California 92121 January 27, 2011 VIA EDGAR AND FEDEX Ms.

December 13, 2010 CORRESP

- 1 -

Fredrikson & Byron, P.A. 200 South Sixth Street, Suite 4000 Minneapolis, MN 55402 www.fredlaw.com Direct: (612) 492-7252 Main: (612) 492-7000 Fax: (612) 492-7077 Email: [email protected] December 13, 2010 VIA EDGAR AND FEDEX Ms. Tara L. Harkins Division of Corporate Finance Securities and Exchange Commission 100 F Street, NE Washington, D.C. 20549 Re: SpectraScience, Inc. Form 10-K for the Year

December 10, 2010 EX-24

EX-24

POWER OF ATTORNEY For Executing Forms 3, 4 and 5 The undersigned hereby constitutes and appoints James Dorst, Ryan C.

December 1, 2010 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Other Events, Financial Statements and Exhibits

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 29, 2010 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 41-1448837

December 1, 2010 EX-99.1

SpectraScience Announces Appointment of Michael Oliver as President and Chief Executive Officer

SpectraScience Announces Appointment of Michael Oliver as President and Chief Executive Officer SAN DIEGO, December 1, 2010 (Marketwire) – SpectraScience, Inc.

November 15, 2010 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2010 Commission file number 0-13092

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2010 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or orga

October 25, 2010 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Regulation FD Disclosure, Financial Statements and Exhibits

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 20, 2010 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 41-1448837 (

October 25, 2010 EX-99.1

SpectraScience Announces Strategic Restructuring of Business

SpectraScience Announces Strategic Restructuring of Business SAN DIEGO, October 25, 2010 (Marketwire) – SpectraScience, Inc.

October 13, 2010 EX-99.1

SpectraScience Names New Chairman of the Board

SpectraScience Names New Chairman of the Board SAN DIEGO, October 13, 2010 (MARKETWIRE) – SpectraScience, Inc.

October 13, 2010 8-K

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 8, 2010 SPECTRASCIENCE, INC. (Exact nam

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 8, 2010 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 41-1448837 (I

September 10, 2010 424B3

PROSPECTUS SPECTRASCIENCE, INC. 25,225,849 Shares of Common Stock

Filed Pursuant to Rule 424(b)(3) File No. 333-167826 PROSPECTUS SPECTRASCIENCE, INC. 25,225,849 Shares of Common Stock This Prospectus relates to the sale of up to 25,225,849 shares of SpectraScience, Inc. common stock, par value $0.01 per share, the (“Common Stock”), which include: · 15,766,155 shares of Common Stock underlying a like number of shares of Series C Convertible Preferred Stock; · 7,

September 9, 2010 CORRESP

September 9, 2010

September 9, 2010 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporate Finance 100 F Street, N.E. Washington, D.C. 20549 Attention: Ms. Celia A. Soehner, Attorney Re: SpectraScience, Inc. (the “Company”) Registration Statement on Form S-1 File No. 333-167826 Dear Ms. Soehner: On behalf of the Company, the undersigned respectfully requests that the above-referenced Registration S

September 2, 2010 424B3

PROSPECTUS SPECTRASCIENCE, INC. 40,249,213 Shares of Common Stock

Filed Pursuant to Rule 424(b)(3) Registration Statement No. 333-164430 PROSPECTUS SUPPLEMENT NO. 2 (TO PROSPECTUS DATED February 12, 2010, as updated and supplemented by Post-Effective Amendment No. 1 dated May 11, 2010) PROSPECTUS SPECTRASCIENCE, INC. 40,249,213 Shares of Common Stock This prospectus, as updated and supplemented by Post-Effective Amendment No. 1 (collectively, the “Prospectus”),

August 26, 2010 EX-10.5

SPECTRASCIENCE, INC. Maximum of 25,000,000 Shares ($5,000,000) SELECTED DEALERS AGREEMENT

EXHIBIT 10.5 SPECTRASCIENCE, INC. Maximum of 25,000,000 Shares ($5,000,000) SELECTED DEALERS AGREEMENT As of July 2, 2009 Dear Sirs: SpectraScience, Inc. (the “Company”) is offering for sale the shares of common stock (the “Shares”) and warrants to purchase common stock (the “Warrants”, together with the Shares, the “Units”) pursuant to the Company’s Confidential Private Placement Memorandum dated

August 26, 2010 S-1/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 AMENDMENT NO. 2 TO FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter)

Registration No. 333-167826 As filed with the U.S. Securities and Exchange Commission on August 26, 2010 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 AMENDMENT NO. 2 TO FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 3845 94-3096597 (State or other jurisdiction of incor

August 26, 2010 EX-4.6

Void after 5:00 p.m. Central Standard Time, on ____________ ___, 20__ Warrant to Purchase ____________Shares of Common Stock. FORM OF WARRANT TO PURCHASE COMMON STOCK SPECTRASCIENCE, INC.

EXHIBIT 4.6 THIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 (THE "ACT") NOR UNDER ANY STATE SECURITIES LAW AND MAY NOT BE PLEDGED, SOLD, ASSIGNED OR OTHERWISE TRANSFERRED UNTIL (1) A REGISTRATION STATEMENT UNDER THE ACT AND ANY APPLICABLE STATE SECURITIES LAW HAS BECOME EFFECTIVE WITH RESPECT THERETO, OR (2)RECEIPT BY THE COMPANY OF AN OPINION OF COUNSEL TO THE COMPANY TO THE

August 26, 2010 EX-10.6

SPECTRASCIENCE, INC. Maximum of 25,000,000 Shares ($5,000,000) SELECTED DEALERS AGREEMENT

EXHIBIT 10.6 SPECTRASCIENCE, INC. Maximum of 25,000,000 Shares ($5,000,000) SELECTED DEALERS AGREEMENT As of April 6, 2010 Dear Sirs: SpectraScience, Inc. (the “Company”) is offering for sale the shares of common stock (the “Shares”) and warrants to purchase common stock (the “Warrants”, together with the Shares, the “Units”) pursuant to the Company’s Confidential Private Placement Memorandum date

August 26, 2010 CORRESP

[Fredrikson & Byron Letterhead]

[Fredrikson & Byron Letterhead] Fredrikson & Byron, P.A. 200 South Sixth Street, Suite 4000 Minneapolis, MN 55402 www.fredlaw.com Direct: (612) 492-7252 Main: (612) 492-7000 Fax: (612) 492-7077 Email: [email protected] August 26, 2010 VIA EDGAR AND FEDEX Ms. Celia A. Soehner Division of Corporate Finance Securities and Exchange Commission 100 F Street, NE Washington, D.C. 20549 Re: SpectraScienc

August 16, 2010 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2010 Commission file number 0-13092 SPECT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2010 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or organizat

August 5, 2010 CORRESP

[Fredrikson & Byron Letterhead]

[Fredrikson & Byron Letterhead] Fredrikson & Byron, P.A. 200 South Sixth Street, Suite 4000 Minneapolis, MN 55402 www.fredlaw.com Direct: (612) 492-7252 Main: (612) 492-7000 Fax: (612) 492-7077 Email: [email protected] August 5, 2010 VIA EDGAR AND FEDEX Ms. Celia A. Soehner Division of Corporate Finance Securities and Exchange Commission 100 F Street, NE Washington, D.C. 20549 Re: SpectraScience

August 5, 2010 S-1/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 AMENDMENT NO. 1 TO FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter)

Registration No. 333-167826 As filed with the U.S. Securities and Exchange Commission on August 5, 2010 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 AMENDMENT NO. 1 TO FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 3845 94-3096597 (State or other jurisdiction of incorp

June 28, 2010 S-1

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter)

Registration No. 333- As filed with the U.S. Securities and Exchange Commission on June 28, 2010 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 3845 94-3096597 (State or other jurisdiction of incorporation or organization) (

June 24, 2010 EX-4.6

CERTIFICATE OF DESIGNATION OF RIGHTS AND PREFERENCES OF SERIES C PREFERRED STOCK OF SPECTRASCIENCE, INC. (PURSUANT TO MINNESOTA STATUTES, SECTION 302A.401, SUBD. 3(B))

EXHIBIT 4.6 CERTIFICATE OF DESIGNATION OF RIGHTS AND PREFERENCES OF SERIES C PREFERRED STOCK OF SPECTRASCIENCE, INC. (PURSUANT TO MINNESOTA STATUTES, SECTION 302A.401, SUBD. 3(B)) The undersigned, being the Secretary of SpectraScience, Inc., a corporation organized and existing under the laws of the State of Minnesota (the “Company”), in accordance with the provisions of Minnesota Statutes, Sectio

June 24, 2010 EX-4.5

Void after 5:00 p.m. Central Standard Time, on ____________ ___, 20__ Warrant to Purchase ____________Shares of Common Stock. FORM OF WARRANT TO PURCHASE COMMON STOCK SPECTRASCIENCE, INC.

EXHIBIT 4.5 THIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 (THE "ACT") NOR UNDER ANY STATE SECURITIES LAW AND MAY NOT BE PLEDGED, SOLD, ASSIGNED OR OTHERWISE TRANSFERRED UNTIL (1) A REGISTRATION STATEMENT UNDER THE ACT AND ANY APPLICABLE STATE SECURITIES LAW HAS BECOME EFFECTIVE WITH RESPECT THERETO, OR (2)RECEIPT BY THE COMPANY OF AN OPINION OF COUNSEL TO THE COMPANY TO THE

June 24, 2010 EX-4.4

FORM OF SUBSCRIPTION AGREEMENT IMPORTANT: PLEASE READ CAREFULLY BEFORE SIGNING SIGNIFICANT REPRESENTATIONS ARE CALLED FOR HEREIN

EXHIBIT 4.4 FORM OF SUBSCRIPTION AGREEMENT IMPORTANT: PLEASE READ CAREFULLY BEFORE SIGNING SIGNIFICANT REPRESENTATIONS ARE CALLED FOR HEREIN SpectraScience, Inc. , 2010 11568-11 Sorrento Valley Rd. San Diego, CA 92121 Gentlemen: The undersigned, (“Investor”) hereby tenders this subscription and applies for the purchase of Units (the “Securities”) of SpectraScience, Inc. (the “Company”) at $10.00 p

June 24, 2010 8-K

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 18, 2010 SPECTRASCIENCE, INC. (Exact name

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 18, 2010 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 41-1448837 (I.R

June 4, 2010 EX-24

EX-24

POWER OF ATTORNEY The undersigned hereby constitutes and appoints James Hitchin, James Dorst and Scott J.

May 28, 2010 8-K

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 21, 2010 SPECTRASCIENCE, INC. (Exact name o

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 21, 2010 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 41-1448837 (I.R.

May 28, 2010 EX-99.1

Exhibit 99.1

Exhibit 99.1 SpectraScience Appoints Sheldon L. Miller Esq. to Its Board of Directors SAN DIEGO, CA-(Marketwire - May 26, 2010) - SpectraScience, Inc. (OTCBB: SCIE), a San Diego based medical device company, announced today that it has appointed Sheldon L. Miller Esq. to its Board of Directors. Jim Hitchin, SpectraScience's CEO, said, "We are extremely pleased that Mr. Miller has accepted a positi

May 20, 2010 424B3

PROSPECTUS SPECTRASCIENCE, INC. 40,249,213 Shares of Common Stock

424B3 1 v185914424b3.htm Filed Pursuant to Rule 424(b)(3) Registration Statement No. 333-164430 PROSPECTUS SUPPLEMENT NO. 1 (TO PROSPECTUS DATED February 12, 2010, as updated and supplemented by Post-Effective Amendment No. 1 dated May 11, 2010) PROSPECTUS SPECTRASCIENCE, INC. 40,249,213 Shares of Common Stock This prospectus, as updated and supplemented by Post-Effective Amendment No. 1 (collecti

May 18, 2010 424B3

PROSPECTUS SPECTRASCIENCE, INC. 40,249,213 Shares of Common Stock

424B3 1 v185830424b3.htm Filed Pursuant to Rule 424(b)(3) File No. 333-164430 PROSPECTUS SPECTRASCIENCE, INC. 40,249,213 Shares of Common Stock This Prospectus relates to the sale of up to 40,249,213 shares of SpectraScience, Inc. common stock, par value $0.01 per share, the (“Common Stock”), which include: · 25,000,000 shares of Common Stock underlying a like number of shares of Series B Converti

May 17, 2010 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2010 Commission file number 0-13092 SPEC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 FORM 10-Q QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2010 Commission file number 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1448837 (State or other jurisdiction of incorporation or organiza

May 11, 2010 POS AM

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Post-Effective Amendment No. 1 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter)

Registration No. 333-164430 As filed with the U.S. Securities and Exchange Commission on May 11, 2010 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Post-Effective Amendment No. 1 to FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 3845 94-3096597 (State or other jurisdict

May 11, 2010 EX-4.7

CERTIFICATE OF DESIGNATION OF COMMON STOCK

EXHIBIT 4.7 CERTIFICATE OF DESIGNATION OF COMMON STOCK I, James Hitchin, Chief Executive Officer of SpectraScience, Inc., a Minnesota corporation (the “Company”), do hereby certify that on April 9, 2010, under the authority of Article II, Section 2.01 of the Company’s Amended and Restated Articles of Incorporation (the “Articles”), the Board of Directors of the Company unanimously adopted a resolu

May 11, 2010 EX-4.6

CERTIFICATE OF DESIGNATION OF RIGHTS AND PREFERENCES OF SERIES C PREFERRED STOCK OF SPECTRASCIENCE, INC. (PURSUANT TO MINNESOTA STATUTES, SECTION 302A.401, SUBD. 3(B))

EXHIBIT 4.6 CERTIFICATE OF DESIGNATION OF RIGHTS AND PREFERENCES OF SERIES C PREFERRED STOCK OF SPECTRASCIENCE, INC. (PURSUANT TO MINNESOTA STATUTES, SECTION 302A.401, SUBD. 3(B)) The undersigned, being the Secretary of SpectraScience, Inc., a corporation organized and existing under the laws of the State of Minnesota (the “Company”), in accordance with the provisions of Minnesota Statutes, Sectio

March 31, 2010 10-K

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K x ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: DECEMBER 31, 2009 o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SEC

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K x ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: DECEMBER 31, 2009 o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-13092 SPECTRASCIENCE, INC. (Exact name of registrant as speci

February 12, 2010 424B3

PROSPECTUS SPECTRASCIENCE, INC. 40,249,213 Shares of Common Stock

Filed Pursuant to Rule 424(b)(3) File No. 333-164430 PROSPECTUS SPECTRASCIENCE, INC. 40,249,213 Shares of Common Stock This Prospectus relates to the sale of up to 40,249,213 shares of SpectraScience, Inc. common stock, par value $0.01 per share, the (“Common Stock”), which include: · 25,000,000 shares of Common Stock underlying a like number of shares of Series B Convertible Preferred Stock; · 12

February 11, 2010 CORRESP

February 11, 2010

February 11, 2010 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporate Finance 100 F Street, N.E. Washington, D.C. 20549 Attention: Ms. Celia A. Soehner, Attorney Re: SpectraScience, Inc. (the “Company”) Registration Statement on Form S-1 File No. 333-164430 Dear Ms. Soehner: On behalf of the Company, the undersigned respectfully requests that the above-referenced Registration S

February 10, 2010 CORRESP

February 10, 2010

February 10, 2010 VIA EDGAR AND FACSIMILE U.S. Securities and Exchange Commission Division of Corporate Finance 100 F Street, N.E. Washington, D.C. 20549 Attention: Ms. Celia A. Soehner, Attorney Re: SpectraScience, Inc. (the “Company”) Registration Statement on Form S-1 File No. 333-164430 Dear Ms. Soehner: On behalf of the Company, the undersigned respectfully requests that the above-referenced

February 8, 2010 S-1/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Pre-Effective Amendment No. 2 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter)

Registration No. 333-164430 As filed with the U.S. Securities and Exchange Commission on February 8, 2010 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Pre-Effective Amendment No. 2 to FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 3845 94-3096597 (State or other jurisd

February 3, 2010 S-1/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Pre-Effective Amendment No. 1 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter)

Registration No. 333-164430 As filed with the U.S. Securities and Exchange Commission on February 2, 2010 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Pre-Effective Amendment No. 1 to FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 3845 94-3096597 (State or other jurisd

February 3, 2010 CORRESP

Sincerely, /s/ Jim Hitchin Jim Hitchin Chairman and Chief Executive Officer (858) 847-0200

February 2, 2010 Via EDGAR and Facsimile Ms. Celia A. Soehner, Attorney United States Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: SpectraScience, Inc. Registration Statement on Form S-1 Filed on January 20, 2010 File No. 333-164430 Dear Ms. Soehner: SpectraScience, Inc. (the “Company”) submits this letter in response to comments

January 20, 2010 EX-21.1

SUBSIDIARIES

EXHIBIT 21.1 SUBSIDIARIES Luma Imaging Corporation, a Delaware Corporation, wholly owned by the Registrant.

January 20, 2010 S-1

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter)

As filed with the U.S. Securities and Exchange Commission on January 20, 2010 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 3845 94-3096597 (State or other jurisdiction of incorporation or organization

December 21, 2009 8-K

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Filed pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 17, 2009 SPECTRASCIENCE, INC. (E

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Filed pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 17, 2009 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 41-14

November 16, 2009 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 Form 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2009 or o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 0-13092 SPECTRASCIENCE,

November 16, 2009 EX-3.3

CERTIFICATE OF AMENDMENT TO ARTICLES OF INCORPORATION OF SPECTRASCIENCE, INC.

EXHIBIT 3.3 CERTIFICATE OF AMENDMENT TO ARTICLES OF INCORPORATION OF SPECTRASCIENCE, INC. The undersigned, being the Chief Executive Officer of SpectraScience, Inc., a Minnesota corporation (the “Corporation”), in accordance with the Minnesota Business Corporation Act, does hereby certify that the Board of Directors adopted the following resolutions effective as of September 21, 2009: AMENDMENT OF

November 6, 2009 EX-4.5

Void after 5:00 p.m. Central Standard Time, on ____________ ___, 20__ Warrant to Purchase ____________Shares of Common Stock. FORM OF WARRANT TO PURCHASE COMMON STOCK SPECTRASCIENCE, INC.

EXHIBIT 4.5 THIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 (THE "ACT") NOR UNDER ANY STATE SECURITIES LAW AND MAY NOT BE PLEDGED, SOLD, ASSIGNED OR OTHERWISE TRANSFERRED UNTIL (1) A REGISTRATION STATEMENT UNDER THE ACT AND ANY APPLICABLE STATE SECURITIES LAW HAS BECOME EFFECTIVE WITH RESPECT THERETO, OR (2)RECEIPT BY THE COMPANY OF AN OPINION OF COUNSEL TO THE COMPANY TO THE

November 6, 2009 EX-4.4

SUBSCRIPTION AGREEMENT IMPORTANT: PLEASE READ CAREFULLY BEFORE SIGNING SIGNIFICANT REPRESENTATIONS ARE CALLED FOR HEREIN

EXHIBIT 4.4 SUBSCRIPTION AGREEMENT IMPORTANT: PLEASE READ CAREFULLY BEFORE SIGNING SIGNIFICANT REPRESENTATIONS ARE CALLED FOR HEREIN SpectraScience, Inc. 11568-11 Sorrento Valley Rd. San Diego, CA 92121 Gentlemen: The undersigned, (“Investor”) hereby tenders this subscription and applies for the purchase of Units (the “Securities”) of SpectraScience, Inc. (the “Company”) at $10.00 per unit. The ag

November 6, 2009 EX-4.6

CERTIFICATE OF DESIGNATION OF RIGHTS AND PREFERENCES OF SERIES B PREFERRED STOCK OF SPECTRASCIENCE, INC. (PURSUANT TO MINNESOTA STATUTES, SECTION 302A.401, SUBD. 3(B))

EXHIBIT 4.6 CERTIFICATE OF DESIGNATION OF RIGHTS AND PREFERENCES OF SERIES B PREFERRED STOCK OF SPECTRASCIENCE, INC. (PURSUANT TO MINNESOTA STATUTES, SECTION 302A.401, SUBD. 3(B)) The undersigned, being the Secretary of SpectraScience, Inc., a corporation organized and existing under the laws of the State of Minnesota (the “Company”), in accordance with the provisions of Minnesota Statutes, Sectio

November 6, 2009 8-K

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Filed pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 31, 2009 SPECTRASCIENCE, INC. (Ex

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Filed pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 31, 2009 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 41-144

August 21, 2009 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.)

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.

August 14, 2009 EX-4.4

CERTIFICATE OF DESIGNATION OF RIGHTS AND PREFERENCES OF SERIES B PREFERRED STOCK OF SPECTRASCIENCE, INC. (PURSUANT TO MINNESOTA STATUTES, SECTION 302A.401, SUBD. 3(B))

Exhibit 4.4 CERTIFICATE OF DESIGNATION OF RIGHTS AND PREFERENCES OF SERIES B PREFERRED STOCK OF SPECTRASCIENCE, INC. (PURSUANT TO MINNESOTA STATUTES, SECTION 302A.401, SUBD. 3(B)) The undersigned, being the Secretary of SpectraScience, Inc., a corporation organized and existing under the laws of the State of Minnesota (the “Company”), in accordance with the provisions of Minnesota Statutes, Sectio

August 14, 2009 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 Form 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2009 or o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 0-13092 SPECTRASCIENCE, Inc.

August 14, 2009 EX-4.5

Void after 5:00 p.m. Central Standard Time, on ____________ ___, 20__ Warrant to Purchase ____________Shares of Common Stock. FORM OF WARRANT TO PURCHASE COMMON STOCK SPECTRASCIENCE, INC.

Exhibit 4.5 THIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 (THE "ACT") NOR UNDER ANY STATE SECURITIES LAW AND MAY NOT BE PLEDGED, SOLD, ASSIGNED OR OTHERWISE TRANSFERRED UNTIL (1) A REGISTRATION STATEMENT UNDER THE ACT AND ANY APPLICABLE STATE SECURITIES LAW HAS BECOME EFFECTIVE WITH RESPECT THERETO, OR (2)RECEIPT BY THE COMPANY OF AN OPINION OF COUNSEL TO THE COMPANY TO THE

August 4, 2009 EX-99.1

EXHIBIT 99.1

EXHIBIT 99.1 F. Duwaine Townsen Joins SpectraScience Board of Directors SAN DIEGO, July 28 /PRNewswire-FirstCall/ - SpectraScience, Inc. (OTC Bulletin Board: SCIE - News), a San Diego based medical device company, today announced that F. Duwaine Townsen, Co-Founder/Managing Director of EndPoint Late-Stage Fund has joined its Board of Directors. He began his career with Arthur Young & Company follo

August 4, 2009 8-K

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Filed pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 21, 2009 SPECTRASCIENCE, INC. (Exact

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Filed pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 21, 2009 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 41-144883

August 4, 2009 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.)

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.

May 22, 2009 8-K

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Filed pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 18, 2009 SPECTRASCIENCE, INC. (Exact

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Filed pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 18, 2009 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 41-1448837

May 15, 2009 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 Form 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2009 or o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 0-13092 SPECTRASCIENCE, Inc

April 30, 2009 EX-21.1

SUBSIDIARIES

EXHIBIT 21.1 SUBSIDIARIES Luma Imaging Corporation, a Delaware Corporation, wholly owned by the Registrant.

April 30, 2009 EX-10.1

FORM OF DIRECTORS’ OPTION AGREEMENT STOCK OPTION AGREEMENT

EXHIBIT 10.1 FORM OF DIRECTORS’ OPTION AGREEMENT STOCK OPTION AGREEMENT THIS AGREEMENT, made this day of 200, by and between SpectraScience, Inc., a Minnesota corporation (the "Company”) and ("Optionee"). 1. Grant of Option. Pursuant to its Amended 2001 Stock Option Plan (the "Plan), the Company hereby grants to Optionee, on the date set forth above, the right and option (hereinafter called the "o

April 30, 2009 S-1

As filed with the U.S. Securities and Exchange Commission on April 29, 2009

As filed with the U.S. Securities and Exchange Commission on April 29, 2009 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 3845 94-3096597 (State or other jurisdiction of incorporation or organization)

April 30, 2009 EX-3.2

SPECTRASCIENCE, INC AMENDED BYLAWS ARTICLE I OFFICERS, CORPORATE SEAL AND SHAREHOLDER CONTROL AGREEMENT

EXHIBIT 3.2 SPECTRASCIENCE, INC AMENDED BYLAWS ARTICLE I OFFICERS, CORPORATE SEAL AND SHAREHOLDER CONTROL AGREEMENT SECTION 1.01. REGISTERED AND OTHER OFFICES. The registered office of the corporation in Minnesota shall be that set forth in the Articles of Incorporation or statement of the Board of Directors filed with the Secretary of State of Minnesota changing the registered office in the manne

March 30, 2009 10-K

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K x ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: DECEMBER 31, 2008 o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SEC

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K x ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: DECEMBER 31, 2008 o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-13092 SPECTRASCIENCE, INC. (Name of small business issuer in

February 4, 2009 EX-10.1

COMMON STOCK PURCHASE AGREEMENT

EXHIBIT 10.1 EXECUTION COPY COMMON STOCK PURCHASE AGREEMENT COMMON STOCK PURCHASE AGREEMENT (the “Agreement”), dated as of January 30, 2009 by and between SPECTRASCIENCE, INC., a Minnesota corporation (the “Company”), and FUSION CAPITAL FUND II, LLC, an Illinois limited liability company (the “Buyer”). Capitalized terms used herein and not otherwise defined herein are defined in Section 10 hereof.

February 4, 2009 8-K

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Filed pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 30, 2009 SPECTRASCIENCE, INC. (Ex

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Filed pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 30, 2009 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 41-144

February 4, 2009 EX-10.2

* * * * * *

EXHIBIT 10.2 REGISTRATION RIGHTS AGREEMENT REGISTRATION RIGHTS AGREEMENT (this "Agreement"), dated as of January 30, 2009, by and between SPECTRASCIENCE, INC., a Minnesota corporation, (the "Company"), and FUSION CAPITAL FUND II, LLC (together with it permitted assigns, the “Buyer”). Capitalized terms used herein and not otherwise defined herein shall have the respective meanings set forth in the

December 12, 2008 CORRESP

11568-11 Sorrento Valley Road San Diego, California 92121

11568-11 Sorrento Valley Road San Diego, California 92121 December 12, 2008 Via Edgar and Fax (202) 772-9218 Mr.

November 13, 2008 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 Form 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2008 or o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 0-13092 SPECTRASCIENCE,

August 14, 2008 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 Form 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2008 or o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 0-13092 SPECTRASCIENCE, Inc.

May 15, 2008 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON D.C. 20549 Form 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2008 or o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 0-13092 SPECTRASCIENCE, Inc

May 2, 2008 8-K

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): April 28, 2008 SPECTRASCIENCE, INC. (Exact name

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): April 28, 2008 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State or Other Jurisdiction of Incorporation) 0-13092 41-1448837 (Commission File No.) (IRS Emp

May 2, 2008 EX-16.1

May 1, 2008

Exhibit 16.1 May 1, 2008 Office of the Chief Accountant Securities and Exchange Commission 100 F Street, N.E. Washington, D.C. 20549 Re: SpectraScience, Inc. Commission File No. 0-13902 Ladies and Gentlemen: We have read Item 4.01 included in the Form 8-K dated April 28, 2008 of SpectraScience, Inc. which we understand will be filed with the Securities and Exchange Commission and are in agreement

April 8, 2008 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) SpectraScience, Inc. (Name of Registrant as Specified In Its Charter)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.

March 31, 2008 EX-4.3

Void after 5:00 p.m. Central Standard Time, on December 31, 2012 Warrant to Purchase 714,285 Shares of Common Stock. WARRANT TO PURCHASE COMMON STOCK SPECTRASCIENCE, INC.

Exhibit 4.3 THIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF1933 (THE "ACT") NOR UNDER ANY STATE SECURITIES LAW AND MAY NOT BE PLEDGED, SOLD, ASSIGNED OR OTHERWISE TRANSFERRED UNTIL (1) A REGISTRATION STATEMENT UNDER THE ACT AND ANY APPLICABLE STATE SECURITIES LAW HAS BECOME EFFECTIVE WITH RESPECT THERETO, OR (2)RECEIPT BY THE COMPANY OF AN OPINION OF COUNSEL TO THE COMPANY TO THE

March 31, 2008 10KSB

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-KSB

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-KSB (Mark One) x ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: DECEMBER 31, 2007 o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-13092 SPECTRASCIENCE, INC. (Development Stage En

March 18, 2008 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.

December 11, 2007 EX-99.1

Jim Dorst joins SpectraScience as CFO

EXHIBIT 99.1 FOR IMMEDIATE RELEASE Jim Dorst joins SpectraScience as CFO December 10, 2007 San Diego, CA SpectraScience, Inc. (SCIE.OB) announced today that Jim Dorst has joined the Company as its Vice President of Finance and Chief Financial Officer. Jim Hitchin the Company’s CEO said, “Jim comes to us with many years of experience in public medical device, manufacturing and software firms. His e

December 11, 2007 8-K

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Filed pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 6, 2007 SPECTRASCIENCE, INC. (Ex

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Filed pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 6, 2007 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 41-144

November 14, 2007 10QSB

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Form 10-QSB

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Form 10-QSB (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2007 o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period fromto Commission file number 0-13092 SPECTRASCIENCE,

November 13, 2007 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT FILED PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report: November 6, 2007 (Date of earliest event reported) SPECTRASCI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT FILED PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report: November 6, 2007 (Date of earliest event reported) SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 41-1448837 (Commi

November 13, 2007 EX-2.1

Table of Contents STOCK PURCHASE AGREEMENT BY AND AMONG SPECTRASCIENCE, INC. EUCLID PARTNERS IV, L.P., EUCLIDSR PARTNERS, L.P., EUCLIDSR BIOTECHNOLOGY PARTNERS, L.P., STEPHEN L. WATSON ROSS FLEWELLING STOCK PURCHASE AGREEMENT

Table of Contents EXHIBIT 2.1 STOCK PURCHASE AGREEMENT BY AND AMONG SPECTRASCIENCE, INC. AND EUCLID PARTNERS IV, L.P., EUCLIDSR PARTNERS, L.P., EUCLIDSR BIOTECHNOLOGY PARTNERS, L.P., STEPHEN L. WATSON AND ROSS FLEWELLING STOCK PURCHASE AGREEMENT This Agreement (the “Agreement”) is entered into as of November 6, 2007, by and among SpectraScience, Inc., a Minnesota corporation (the “Buyer”) and Eucl

November 13, 2007 EX-99.1

SpectraScience Acquires Luma Imaging Corporation

PRESS RELEASE SpectraScience Acquires Luma Imaging Corporation November 8, 2007 San Diego, CA SpectraScience, Inc.

October 18, 2007 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT FILED PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report: October 17, 2007 (Date of earliest event reported) SPECTRASCI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT FILED PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report: October 17, 2007 (Date of earliest event reported) SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 41-1448837 (Commi

October 1, 2007 EX-99.1

Exhibit 99.1

Exhibit 99.1 PRESS RELEASE SpectraScience Appoints the Honorable Tommy Thompson to its Board of Directors FOR IMMEDIATE RELEASE September 25, 2007 San Diego, CA SpectraScience, Inc. (SCIE.OB) announced today that it has elected the Honorable Tommy Thompson to its Board of Directors. Before entering the private sector in 2005, Secretary Thompson enjoyed a long and distinguished career in public ser

October 1, 2007 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Filed pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 28, 2007 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota 000-13092 41-1448837 (State of other jurisdiction of incorporation) (Commission File N

August 14, 2007 EX-4.2

STOCK PURCHASE WARRANT To Purchase Series A Preferred Stock of SPECTRASCIENCE, INC. THIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 (THE “ACT”) NOR UNDER ANY STATE SECURITIES LAW AND MAY NOT BE PLEDGED, SOLD, ASSIGNED OR OTHERWI

Exhibit 4.2 STOCK PURCHASE WARRANT To Purchase Series A Preferred Stock of SPECTRASCIENCE, INC. THIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 (THE “ACT”) NOR UNDER ANY STATE SECURITIES LAW AND MAY NOT BE PLEDGED, SOLD, ASSIGNED OR OTHERWISE TRANSFERRED UNTIL (1) A REGISTRATION STATEMENT UNDER THE ACT AND ANY APPLICABLE STATE SECURITIES LAW HAS BECOME EFFECTIVE WITH RESPECT

August 14, 2007 EX-4.1

CERTIFICATE OF CREATION OF SERIES A PREFERRED STOCK SPECTRASCIENCE, INC.

Exhibit 4.1 CERTIFICATE OF CREATION OF SERIES A PREFERRED STOCK OF SPECTRASCIENCE, INC. I, James Hitchin, Chief Executive Officer of SpectraScience, Inc. a Minnesota corporation (the “Company”), do hereby certify that on June 12, 2007, under the authority of Article II, Section 2.01 of the Company's Amended and Restated Articles of Incorporation, the Board of Directors of the Company unanimously a

August 14, 2007 10QSB

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Form 10-QSB

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Form 10-QSB (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2007 o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 0-13092 SPECTRASCIENCE, Inc.

June 25, 2007 8-K

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Filed pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 18, 2007 SPECTRASCIENCE, INC. (Exact

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Filed pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 18, 2007 SPECTRASCIENCE, INC. (Exact name of registrant as specified in its charter) Minnesota (State of other jurisdiction of incorporation) 000-13092 (Commission File Number) 41-144883

June 25, 2007 EX-99.1

Exhibit 99.1

Exhibit 99.1 PRESS RELEASE SpectraScience Appoints John Pappajohn to Board of Directors FOR IMMEDIATE RELEASE June 18, 2006 San Diego, CA SpectraScience, Inc. (SCIE.OB) announced today that it has elected John Pappajohn to its Board of Directors. Mr. Pappajohn is a long time health care venture capital investor based in Des Moines, Iowa. Since 1969, Mr. Pappajohn has been the President and princip

May 14, 2007 10QSB

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Form 10-QSB

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Form 10-QSB (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2007 o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 0-13092 SPECTRASCIENCE, Inc

March 28, 2007 10KSB

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-KSB

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-KSB (Mark One) x ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: DECEMBER 31, 2006 o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-13092 SPECTRASCIENCE, INC. (Development Stage En

November 14, 2006 10QSB

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Form 10-QSB

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Form 10-QSB (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2006 o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 0-13092 SPECTRASCIENCE,

August 16, 2006 10QSB/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Form 10-QSB/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Form 10-QSB/A (Mark One) [X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2006 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 0-13092 SPECTRASCIENCE

August 11, 2006 10QSB

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Form 10-QSB

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Form 10-QSB (Mark One) [X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period endedJune 30, 2006 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period fromto Commission file number 0-13092 SPECTRASCIENCE, In

May 12, 2006 10QSB

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Form 10-QSB

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Form 10-QSB (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2006 o TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 0-13092 SPECTRASCIENCE, Inc

March 31, 2006 10KSB

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-KSB

Back to Table of Contents Index to Financial Statements UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

March 31, 2006 EX-14

SpectraScience, Inc. Code of Ethics

EXHIBIT 14 SpectraScience, Inc. Code of Ethics This Code of Ethics is approved by the Board of Directors and applies to all employees, and officers and directors of the Company. It contains standards necessary to promote: honest and ethical conduct, including the ethical handling of actual or apparent conflicts of interest between personal and professional relationships, and full, fair, accurate,

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