SPNE / SeaSpine Holdings Corp - Pengajuan SECLaporan Tahunan, Pernyataan Proksi

SeaSpine Holdings Corp
US ˙ NASDAQ ˙ US81255T1088
HINDI NA ACTIVE ANG SIMBONG ITO

Mga Batayang Estadistika
LEI 5493006QNC6E00LJ7M10
CIK 1637761
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to SeaSpine Holdings Corp
SEC Filings (Chronological Order)
Halaman ini menyediakan daftar lengkap dan kronologis dari Pengajuan SEC, tidak termasuk pengajuan kepemilikan yang kami sediakan di tempat lain.
January 17, 2023 15-12G

_____________________________________________________________________________________________________________________________________________________________________________________ UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20

15-12G 1 spne-form15.htm 15-12G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 15 Certification and Notice of Termination of Registration under Section 12(g) of the Securities Exchange Act of 1934 or Suspension of Duty to File Reports Under Sections 13 and 15(d) of the Securities Exchange Act of 1934. Commission File Number: 001-36905 SeaSpine Holdings Corporation (Ex

January 6, 2023 S-8 POS

As filed with the Securities and Exchange Commission on January 5, 2023

As filed with the Securities and Exchange Commission on January 5, 2023 Registration No.

January 6, 2023 S-8 POS

As filed with the Securities and Exchange Commission on January 5, 2023

S-8 POS 1 d431696ds8pos.htm S-8 POS As filed with the Securities and Exchange Commission on January 5, 2023 Registration No. 333-257068 Registration No. 333-240377 Registration No. 333-228217 Registration No. 333-226046 Registration No. 333-225291 Registration No. 333-223435 Registration No. 333-216448 Registration No. 333-211887 Registration No. 333-205334 SECURITIES AND EXCHANGE COMMISSION WASHI

January 6, 2023 S-8 POS

As filed with the Securities and Exchange Commission on January 5, 2023

As filed with the Securities and Exchange Commission on January 5, 2023 Registration No.

January 6, 2023 S-8 POS

As filed with the Securities and Exchange Commission on January 5, 2023

As filed with the Securities and Exchange Commission on January 5, 2023 Registration No.

January 6, 2023 S-8 POS

As filed with the Securities and Exchange Commission on January 5, 2023

S-8 POS 1 d431696ds8pos.htm S-8 POS As filed with the Securities and Exchange Commission on January 5, 2023 Registration No. 333-257068 Registration No. 333-240377 Registration No. 333-228217 Registration No. 333-226046 Registration No. 333-225291 Registration No. 333-223435 Registration No. 333-216448 Registration No. 333-211887 Registration No. 333-205334 SECURITIES AND EXCHANGE COMMISSION WASHI

January 6, 2023 S-8 POS

As filed with the Securities and Exchange Commission on January 5, 2023

As filed with the Securities and Exchange Commission on January 5, 2023 Registration No.

January 6, 2023 POS AM

As filed with the Securities and Exchange Commission on January 5, 2023

POS AM 1 d399002dposam.htm POS AM As filed with the Securities and Exchange Commission on January 5, 2023 Registration No. 333-258527 Registration No. 333-248136 Registration No. 333-216450 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-3 REGISTRATION STATEMENT NO. 333-258527 FORM S-3 REGISTRATION STATEMENT NO. 333-248136 FORM S-3 R

January 6, 2023 S-8 POS

As filed with the Securities and Exchange Commission on January 5, 2023

As filed with the Securities and Exchange Commission on January 5, 2023 Registration No.

January 6, 2023 POS AM

As filed with the Securities and Exchange Commission on January 5, 2023

POS AM 1 d399002dposam.htm POS AM As filed with the Securities and Exchange Commission on January 5, 2023 Registration No. 333-258527 Registration No. 333-248136 Registration No. 333-216450 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-3 REGISTRATION STATEMENT NO. 333-258527 FORM S-3 REGISTRATION STATEMENT NO. 333-248136 FORM S-3 R

January 6, 2023 POS AM

As filed with the Securities and Exchange Commission on January 5, 2023

POS AM 1 d399002dposam.htm POS AM As filed with the Securities and Exchange Commission on January 5, 2023 Registration No. 333-258527 Registration No. 333-248136 Registration No. 333-216450 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-3 REGISTRATION STATEMENT NO. 333-258527 FORM S-3 REGISTRATION STATEMENT NO. 333-248136 FORM S-3 R

January 6, 2023 S-8 POS

As filed with the Securities and Exchange Commission on January 5, 2023

As filed with the Securities and Exchange Commission on January 5, 2023 Registration No.

January 6, 2023 S-8 POS

As filed with the Securities and Exchange Commission on January 5, 2023

S-8 POS 1 d431696ds8pos.htm S-8 POS As filed with the Securities and Exchange Commission on January 5, 2023 Registration No. 333-257068 Registration No. 333-240377 Registration No. 333-228217 Registration No. 333-226046 Registration No. 333-225291 Registration No. 333-223435 Registration No. 333-216448 Registration No. 333-211887 Registration No. 333-205334 SECURITIES AND EXCHANGE COMMISSION WASHI

January 5, 2023 EX-99.1

Orthofix and SeaSpine Announce Completion of Merger of Equals to Create a Leading Global Spine and Orthopedics Company Orthofix and SeaSpine Stockholders Approve Merger

Exhibit 99.1 Orthofix and SeaSpine Announce Completion of Merger of Equals to Create a Leading Global Spine and Orthopedics Company Orthofix and SeaSpine Stockholders Approve Merger Lewisville, Texas ? January 4, 2023 ? Orthofix Medical Inc. (NASDAQ: OFIX) and SeaSpine Holdings Corporation today announced the successful completion of their previously announced merger of equals following the approv

January 5, 2023 EX-3.1

AMENDED AND RESTATED CERTIFICATE OF INCORPORATION SEASPINE HOLDINGS CORPORATION

Exhibit 3.1 AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF SEASPINE HOLDINGS CORPORATION 1. The name of the Corporation is: SeaSpine Holdings Corporation (the ?Corporation?). 2. The address of the Corporation?s registered office in the State of Delaware is 251 Little Falls Drive, in the City of Wilmington, County of New Castle, Delaware, 19808. The name of its registered agent at such addres

January 5, 2023 EX-3.2

BYLAWS SeaSpine Holdings Corporation

Exhibit 3.2 BYLAWS OF SeaSpine Holdings Corporation TABLE OF CONTENTS Page ARTICLE I OFFICES 1 Section 1.1. Registered Office 1 Section 1.2. Other Offices 1 ARTICLE II MEETINGS OF STOCKHOLDERS 1 Section 2.1. Place of Meetings 1 Section 2.2. Annual Meetings 1 Section 2.3. Special Meetings 1 Section 2.4. Notice of Meeting 1 Section 2.5. Quorum 2 Section 2.6. Adjournments 2 Section 2.7. Voting 2 Sect

January 5, 2023 8-K

Changes in Control of Registrant, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Termination of a Material Definitive Agreement, Material Modification to Rights of Security Holders, Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing, Financial Statements and Exhibits, Completion of Acquisition or Disposition of Assets, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 4, 2023 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Comm

January 4, 2023 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 4, 2023 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Comm

December 27, 2022 425

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 27, 2022 SeaSpine Holdin

425 1 d428516d425.htm 425 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 27, 2022 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdic

December 27, 2022 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 27, 2022 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Co

December 27, 2022 425

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 27, 2022 Orthofix Medica

425 1 d398453d425.htm 425 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 27, 2022 Orthofix Medical Inc. (Exact name of registrant as specified in its charter) Delaware 0-19961 98-1340767 (State or other jurisdiction of in

December 5, 2022 425

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 5, 2022 Orthofix Medical I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 5, 2022 Orthofix Medical Inc.

November 30, 2022 425

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 30, 2022 Orthofix Medical

425 1 d359283d425.htm 425 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 30, 2022 Orthofix Medical Inc. (Exact name of Registrant as specified in its charter) Delaware 0-19961 98-1340767 (State or other jurisdiction of inco

November 23, 2022 DEFM14A

SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

DEFM14A 1 d34610ddefm14a.htm DEFM14A Table of Contents SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☒ Definitive Proxy Statement

November 21, 2022 425

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 17, 2022 Orthofix Medical

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 17, 2022 Orthofix Medical Inc.

November 21, 2022 425

Orthofix and SeaSpine Announce John Bostjancic to Serve as CFO for Combined Company Post Closing

Filed by SeaSpine Holdings Corporation pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Filer: SeaSpine Holdings Corporation Subject Company: SeaSpine Holdings Corporation SEC File No.

November 18, 2022 425

The following document was issued to employees of Orthofix Medical Inc. (“Orthofix”) and SeaSpine Holdings Corporation (“SeaSpine”) on November 17, 2022.

425 1 d345453d425.htm 425 Filed by Orthofix Medical Inc. (Commission File No. 0-19961) pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Subject Company: SeaSpine Holdings Corporation (Commission File No. 001-36905) The following document was issued to employees of Orthofix Medical Inc. (“Orthofix”) and SeaSpine

November 18, 2022 425

The following document was issued to employees of Orthofix Medical Inc. (“Orthofix”) and SeaSpine Holdings Corporation (“SeaSpine”) on November 17, 2022.

Filed by SeaSpine Holdings Corporation pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Filer: SeaSpine Holdings Corporation Subject Company: SeaSpine Holdings Corporation SEC File No.

November 18, 2022 425

Orthofix and SeaSpine Announce John Bostjancic to Serve as CFO for Combined Company Post Closing

425 1 d345453d425.htm 425 Filed by Orthofix Medical Inc. (Commission File No. 0-19961) pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Subject Company: SeaSpine Holdings Corporation (Commission File No. 001-36905) Orthofix and SeaSpine Announce John Bostjancic to Serve as CFO for Combined Company Post Closing

November 3, 2022 EX-10.1

Wells Fargo Amendment Number Four to Amended and Restated Credit Agreement and Waiver

Exhibit 10.1 Execution Version AMENDMENT NUMBER FOUR TO AMENDED AND RESTATED CREDIT AGREEMENT AND WAIVER THIS AMENDMENT NUMBER FOUR TO AMENDED AND RESTATED CREDIT AGREEMENT AND WAIVER (this ?Amendment?), dated as of July 15, 2022, is entered into by and among WELLS FARGO BANK, NATIONAL ASSOCIATION, a national banking association (?Wells Fargo?), as administrative agent for each member of the Lende

November 3, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NO.

November 2, 2022 425

©2022, AlphaSense, Inc. All Rights Reserved. AlphaSense is a service mark of AlphaSense, Inc. All other trademarks mentioned belong to their respective owners.

Filed by SeaSpine Holdings Corporation pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Filer: SeaSpine Holdings Corporation Subject Company: SeaSpine Holdings Corporation SEC File No.

November 1, 2022 425

Stronger Together: Building a Leading Global Spine & Orthopedics Company November 1, 2022 Filed by SeaSpine Holdings Corporation pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Excha

Stronger Together: Building a Leading Global Spine & Orthopedics Company November 1, 2022 Filed by SeaSpine Holdings Corporation pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Filer: SeaSpine Holdings Corporation Subject Company: SeaSpine Holdings Corporation SEC File No.

November 1, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): November 1, 2022 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

November 1, 2022 EX-99.1

SeaSpine Announces 45% Revenue Growth and Record Revenue for Third Quarter 2022

Exhibit 99.1 SeaSpine Announces 45% Revenue Growth and Record Revenue for Third Quarter 2022 CARLSBAD, CA (November 1, 2022) ? SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today financial results for the third quarter of 2022. Summary Third Quarter 2022 Financial Results and Recent H

November 1, 2022 425

The following presentation was issued by Orthofix Medical Inc. (“Orthofix”) and SeaSpine Holdings Corporation (“SeaSpine”) on November 1, 2022.

Filed by Orthofix Medical Inc. (Commission File No. 0-19961) pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Subject Company: SeaSpine Holdings Corporation (Commission File No. 001-36905) The following presentation was issued by Orthofix Medical Inc. (“Orthofix”) and SeaSpine Holdings Corporation (“SeaSpine”)

October 12, 2022 425

1

Filed by SeaSpine Holdings Corporation pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Filer: SeaSpine Holdings Corporation Subject Company: SeaSpine Holdings Corporation SEC File No.

October 12, 2022 425

The following is a transcript of a joint call hosted by Orthofix Medical Inc. (“Orthofix”) and SeaSpine Holdings Corporation (“SeaSpine”) on October 11, 2022.

Filed by Orthofix Medical Inc. (Commission File No. 0-19961) pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Subject Company: SeaSpine Holdings Corporation (Commission File No. 001-36905) The following is a transcript of a joint call hosted by Orthofix Medical Inc. (“Orthofix”) and SeaSpine Holdings Corporatio

October 11, 2022 425

Filed by SeaSpine Holdings Corporation

Filed by SeaSpine Holdings Corporation pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Filer: SeaSpine Holdings Corporation Subject Company: SeaSpine Holdings Corporation SEC File No.

October 11, 2022 EX-2.1

Agreement and Plan of Merger, dated as of October 10, 2022, by and among Orthofix Medical Inc., Orca Merger Sub Inc. and SeaSpine Holdings Corporation.

EX-2.1 Exhibit 2.1 EXECUTION VERSION AGREEMENT AND PLAN OF MERGER by and among ORTHOFIX MEDICAL INC., ORCA MERGER SUB INC., and SEASPINE HOLDINGS CORPORATION Dated October 10, 2022 TABLE OF CONTENTS ARTICLE 1 DEFINITIONS 2 1.01 Definitions 2 1.02 Other Definitional Provisions 15 ARTICLE 2 THE MERGER 16 2.01 Shares of Merger Sub 16 2.02 The Merger 16 2.03 Closing 16 2.04 Effective Time 16 2.05 Effe

October 11, 2022 425

In connection with the pending transaction between Orthofix Medical Inc. (“Orthofix”) and SeaSpine Holdings Corporation (“SeaSpine”), Orthofix posted the following on October 11, 2022.

425 1 d412130d425.htm 425 Filed by Orthofix Medical Inc. (Commission File No. 0-19961) pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Subject Company: SeaSpine Holdings Corporation (Commission File No. 001-36905) In connection with the pending transaction between Orthofix Medical Inc. (“Orthofix”) and SeaSpin

October 11, 2022 425

Filed by SeaSpine Holdings Corporation

425 1 d394849d425.htm 425 Filed by SeaSpine Holdings Corporation pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Filer: SeaSpine Holdings Corporation Subject Company: SeaSpine Holdings Corporation SEC File No.: 001-36905 Date: October 11, 2022 Creating a New Leader in Spine and Orthopedics October 11, 2022 Sea

October 11, 2022 EX-99.1

SeaSpine Announces 44% to 45% Preliminary Revenue Growth for Third Quarter 2022 and Raises Full Year 2022 Revenue Guidance

EX-99.1 Exhibit 99.1 SeaSpine Announces 44% to 45% Preliminary Revenue Growth for Third Quarter 2022 and Raises Full Year 2022 Revenue Guidance CARLSBAD, CA (October 11, 2022) – SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today preliminary financial results for the third quarter of

October 11, 2022 425

The following presentation was issued by Orthofix Medical Inc. (“Orthofix”) and SeaSpine Holdings Corporation (“SeaSpine”) on October 11, 2022.

425 1 d412130d425.htm 425 Filed by Orthofix Medical Inc. (Commission File No. 0-19961) pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Subject Company: SeaSpine Holdings Corporation (Commission File No. 001-36905) The following presentation was issued by Orthofix Medical Inc. (“Orthofix”) and SeaSpine Holdings

October 11, 2022 425

The following document was issued by Orthofix Medical Inc. (“Orthofix”) on October 11, 2022.

Filed by Orthofix Medical Inc. (Commission File No. 0-19961) pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Subject Company: SeaSpine Holdings Corporation (Commission File No. 001-36905) The following document was issued by Orthofix Medical Inc. (“Orthofix”) on October 11, 2022. Orthofix – SeaSpine Transactio

October 11, 2022 425

Orthofix Announces Preliminary Third Quarter and Year-To-Date 2022 Net Sales Results

Filed by Orthofix Medical Inc. (Commission File No. 0-19961) pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Subject Company: SeaSpine Holdings Corporation (Commission File No. 001-36905) Orthofix Announces Preliminary Third Quarter and Year-To-Date 2022 Net Sales Results • Third quarter net sales of $114 mill

October 11, 2022 EX-99.1

Orthofix and SeaSpine to Combine in Merger of Equals to Create Leading Global Spine and Orthopedics Company

EX-99.1 Exhibit 99.1 Orthofix and SeaSpine to Combine in Merger of Equals to Create Leading Global Spine and Orthopedics Company • Highly complementary spine and orthopedics portfolios • One of the industry’s broadest biologics and regenerative technology offerings • Differentiated and synergistic enabling technologies • Meaningful cross-selling revenue synergies and cost savings • Financial stren

October 11, 2022 425

The following document was issued by Orthofix Medical Inc. (“Orthofix”) on October 11, 2022.

Filed by Orthofix Medical Inc. (Commission File No. 0-19961) pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Subject Company: SeaSpine Holdings Corporation (Commission File No. 001-36905) The following document was issued by Orthofix Medical Inc. (“Orthofix”) on October 11, 2022. Orthofix – SeaSpine Transactio

October 11, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 10, 2022 SeaSpine Holding

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 10, 2022 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Com

October 11, 2022 425

The following infographic was issued by Orthofix Medical Inc. (“Orthofix”) and SeaSpine Holdings Corporation (“SeaSpine”) on October 11, 2022.

Filed by Orthofix Medical Inc. (Commission File No. 0-19961) pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Subject Company: SeaSpine Holdings Corporation (Commission File No. 001-36905) The following infographic was issued by Orthofix Medical Inc. (“Orthofix”) and SeaSpine Holdings Corporation (“SeaSpine”) o

October 11, 2022 425

SeaSpine Announces 44% to 45% Preliminary Revenue Growth for Third Quarter 2022 and Raises Full Year 2022 Revenue Guidance

425 Filed by SeaSpine Holdings Corporation pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Filer: SeaSpine Holdings Corporation Subject Company: SeaSpine Holdings Corporation SEC File No.

October 11, 2022 425

Filed by SeaSpine Holdings Corporation

Filed by SeaSpine Holdings Corporation pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Filer: SeaSpine Holdings Corporation Subject Company: SeaSpine Holdings Corporation SEC File No.

October 11, 2022 425

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): October 11, 2022 (October 10, 202

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): October 11, 2022 (October 10, 2022) ORTHOFIX MEDICAL INC. (Exact name of registrant as specified in its charter) Delaware 0-19961 98-1340767 (State or other jurisdiction of incorporat

October 11, 2022 425

The following document was issued by Orthofix Medical Inc. (“Orthofix”) on October 11, 2022.

425 1 d412130d425.htm 425 Filed by Orthofix Medical Inc. (Commission File No. 0-19961) pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Subject Company: SeaSpine Holdings Corporation (Commission File No. 001-36905) The following document was issued by Orthofix Medical Inc. (“Orthofix”) on October 11, 2022. Orth

October 11, 2022 425

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 10, 2022 SeaSpine Holding

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 10, 2022 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Com

October 11, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 11, 2022 SeaSpine Holding

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 11, 2022 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Com

October 11, 2022 425

Filed by SeaSpine Holdings Corporation

425 Filed by SeaSpine Holdings Corporation pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Filer: SeaSpine Holdings Corporation Subject Company: SeaSpine Holdings Corporation SEC File No.

October 11, 2022 425

The following presentation was issued by Orthofix Medical Inc. (“Orthofix”) and SeaSpine Holdings Corporation (“SeaSpine”) on October 11, 2022.

Filed by Orthofix Medical Inc. (Commission File No. 0-19961) pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Subject Company: SeaSpine Holdings Corporation (Commission File No. 001-36905) The following presentation was issued by Orthofix Medical Inc. (“Orthofix”) and SeaSpine Holdings Corporation (“SeaSpine”)

October 11, 2022 425

The following document was issued by Orthofix Medical Inc. (“Orthofix”) on October 11, 2022.

425 Filed by Orthofix Medical Inc. (Commission File No. 0-19961) pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Subject Company: SeaSpine Holdings Corporation (Commission File No. 001-36905) The following document was issued by Orthofix Medical Inc. (“Orthofix”) on October 11, 2022. Orthofix – SeaSpine Transa

October 11, 2022 425

The following documents were issued to employees of Orthofix Medical Inc. (“Orthofix”) on October 11, 2022.

Filed by Orthofix Medical Inc. (Commission File No. 0-19961) pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Subject Company: SeaSpine Holdings Corporation (Commission File No. 001-36905) The following documents were issued to employees of Orthofix Medical Inc. (?Orthofix?) on October 11, 2022. Exciting News:

October 11, 2022 425

Stronger Together: Building a Leading Global Spine & Orthopedics Company October 11, 2022 Filed by SeaSpine Holdings Corporation pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Excha

425 1 d391661d425.htm 425 Stronger Together: Building a Leading Global Spine & Orthopedics Company October 11, 2022 Filed by SeaSpine Holdings Corporation pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Filer: SeaSpine Holdings Corporation Subject Company: SeaSpine Holdings Corporation SEC File No.: 001-36905

October 11, 2022 425

Filed by SeaSpine Holdings Corporation

Filed by SeaSpine Holdings Corporation pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Filer: SeaSpine Holdings Corporation Subject Company: SeaSpine Holdings Corporation SEC File No.

October 11, 2022 425

Filed by SeaSpine Holdings Corporation

425 1 d363925d425.htm 425 Filed by SeaSpine Holdings Corporation pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Filer: SeaSpine Holdings Corporation Subject Company: SeaSpine Holdings Corporation SEC File No.: 001-36905 Date: October 11, 2022 Creating a New Leader in Spine and Orthopedics October 11, 2022 Sea

August 4, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NO.

August 4, 2022 EX-3.1

Amended and Restated Certificate of Incorporation, as amended to date

Exhibit 3.1 CERTIFICATE OF AMENDMENT OF AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF SEASPINE HOLDINGS CORPORATION SeaSpine Holdings Corporation (the "Corporation"), a corporation organized and existing under the General Corporation Law of the State of Delaware (the "DGCL"), hereby certifies as follows: 1.This Certificate of Amendment (this "Certificate of Amendment") amends the provisions

August 4, 2022 EX-10.1

Standard Industrial/Commercial Single-Tenant Lease–NET between Monarch RRC Properties, LP and Isotis Orthobiologics, Inc., dated June 1, 2022 (filed as an exhibit to the Quarterly Report on Form 10-Q for the quarter ended June 30, 2022 by SeaSpine Holdings Corporation and incorporated herein by reference).

Exhibit 10.1 STANDARD INDUSTRIAL/COMMERCIAL SINGLE-TENANT LEASE - NET 1.Basic Provisions (?Basic Provisions?). 1.1 Parties. This Lease (?Lease?), dated for reference purposes only June 1, 2022, is made by and between Monarch RRC Properties, LP, a California limited partnership (?Lessor?) and Isotis Orthobiologics, Inc., a Washington corporation (?Lessee?), collectively the ?Parties,? or individual

August 2, 2022 EX-99.1

SeaSpine Reports 19% Revenue Growth and Record Quarterly Revenue for Second Quarter 2022 and Raises Full Year 2022 Revenue Guidance

Exhibit 99.1 SeaSpine Reports 19% Revenue Growth and Record Quarterly Revenue for Second Quarter 2022 and Raises Full Year 2022 Revenue Guidance CARLSBAD, CA (August 2, 2022) – SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today second quarter financial results for the three-months en

August 2, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): August 2, 2022 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

July 18, 2022 8-K

Entry into a Material Definitive Agreement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): July 15, 2022 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

June 10, 2022 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): June 7, 2022 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

June 3, 2022 EX-3.1

Certificate of Amendment to Amended and Restated Certificate of Incorporation dated June 1, 2022

Exhibit 3.1 CERTIFICATE OF AMENDMENT OF AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF SEASPINE HOLDINGS CORPORATION SeaSpine Holdings Corporation (the "Corporation"), a corporation organized and existing under the General Corporation Law of the State of Delaware (the "DGCL"), hereby certifies as follows: 1.This Certificate of Amendment (this "Certificate of Amendment") amends the provisions

June 3, 2022 8-K

Financial Statements and Exhibits, Other Events, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): June 1, 2022 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

May 31, 2022 SD

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD Specialized Disclosure Report SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdict

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD Specialized Disclosure Report SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (IRS Employer Identification No.) 5770 Armada Drive, Carlsbad, California 92008 (Address of principal e

May 9, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NO.

May 3, 2022 EX-99.1

SeaSpine Reports 21 Percent Revenue Growth for First Quarter 2022 and Increases Full Year 2022 Revenue Guidance

Exhibit 99.1 SeaSpine Reports 21 Percent Revenue Growth for First Quarter 2022 and Increases Full Year 2022 Revenue Guidance CARLSBAD, CA (May 3, 2022) ? SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today financial results for the three-months ended March 31, 2022. Summary First Quar

May 3, 2022 8-K

Regulation FD Disclosure, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 2, 2022 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

May 3, 2022 EX-99.2

SeaSpine® Announces New Senior Leadership Team Appointments

Exhibit 99.2 SeaSpine? Announces New Senior Leadership Team Appointments CARLSBAD, CA May 3, 2022 (GLOBAL NEWSWIRE) ? SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, today announced that John Bostjancic, previously the Company?s Senior Vice President, Chief Financial Officer, has assumed expanded

April 22, 2022 DEF 14A

SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

DEF 14A 1 spnedefproxystatement2022.htm DEF 14A SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ý Filed by a Party other than the Registrant o Check the appropriate box: oPreliminary Proxy Statement oConfidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ýDefinitive Proxy Statement oDefinitiv

April 22, 2022 DEFA14A

SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ? Filed by a Party other than the Registrant o Check the appropriate box: oPreliminary Proxy Statement oConfidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) oDefinitive Proxy Statement ?Definitive Additional Materials oSoliciting Material under ?240.

April 8, 2022 PRE 14A

SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

PRE 14A 1 prelimproxystatementv-84x0.htm PRE 14A SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant Filed by a Party other than the Registrant Check the appropriate box: ýPreliminary Proxy Statement oConfidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) oDefinitive Proxy Statement oDefinitive A

March 15, 2022 EX-10.17(G)

OMNIBUS JOINDER AND THIRD AMENDMENT TO AMENDED AND RESTATED CREDIT AGREEMENT AND OTHER LOAN DOCUMENTS

OMNIBUS JOINDER AND THIRD AMENDMENT TO AMENDED AND RESTATED CREDIT AGREEMENT AND OTHER LOAN DOCUMENTS THIS OMNIBUS JOINDER AND THIRD AMENDMENT TO AMENDED AND RESTATED CREDIT AGREEMENT AND OTHER LOAN DOCUMENTS (this ?Amendment?) is made as of October 26, 2021, by and among WELLS FARGO BANK, NATIONAL ASSOCIATION, a national banking association, as administrative agent for each member of the Lender G

March 15, 2022 EX-21.1

Subsidiaries of Registrant

EXHIBIT 21.1 Subsidiaries of SeaSpine Holdings Corporation Name of Subsidiary State or Country of Incorporation or Organization IsoTis International SARL Switzerland IsoTis OrthoBiologics, Inc. Washington IosTis, Inc. Delaware SeaSpine, Inc. Delaware SeaSpine Sales LLC Delaware SeaSpine Orthopedics Corporation Delaware Theken Spine, LLC Ohio SeaSpine Orthopedics IntermediateCo, Inc. Delaware Proje

March 15, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NO.

March 11, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 11, 2022 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

March 11, 2022 EX-99.1

SeaSpine Announces Fourth Quarter and Full-Year 2021 Financial Results and Provides 2022 Revenue Guidance

Exhibit 99.1 SeaSpine Announces Fourth Quarter and Full-Year 2021 Financial Results and Provides 2022 Revenue Guidance CARLSBAD, CA (March 11, 2022) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today financial results for the three-months and full-year ended December 31, 2021. Summ

February 14, 2022 EX-99.2

JOINT FILING AGREEMENT

Exhibit 99.2 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of a Statement on Schedule 13G (including amendments thereto) with respect to the common stock, par value $0.01 per share of SeaSpine Holdings Corporation, and further agree that this Joint Filing Agr

February 14, 2022 SC 13G/A

SPNE / SeaSpine Holdings Corp / Tru St Partnership, L.P. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 7)* SEASPINE HOLDINGS CORPORATION (Name of Issuer) Common Stock, $0.01 par value per share (Title of Class of Securities) 81255T 108 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designa

February 14, 2022 SC 13G

SPNE / SeaSpine Holdings Corp / Avidity Partners Management LP Passive Investment

SC 13G 1 d917870113g.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.)* SeaSpine Holdings Corporation (Name of Issuer) Common Stock, $0.01 par value per share (Title of Class of Securities) 81255T108 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of this Statement) Check the approp

February 14, 2022 EX-99.1

Group Members Tru St Partnership LP Provco Leasing Corporation

Exhibit 99.1 Group Members Tru St Partnership LP Provco Leasing Corporation

February 14, 2022 SC 13G/A

SPNE / SeaSpine Holdings Corp / First Light Asset Management, LLC - AMENDMENT TO FORM SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934* SeaSpine Holdings Corporation (Name of Issuer) Common Stock, $0.01 par value (Title of Class of Securities) 81255T108 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to whi

January 10, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): January 10, 2022 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

January 10, 2022 EX-99.1

SeaSpine Announces Preliminary Fourth Quarter and Full Year 2021 Financial Results, Including Record Fourth Quarter 2021 Revenue

Exhibit 99.1 SeaSpine Announces Preliminary Fourth Quarter and Full Year 2021 Financial Results, Including Record Fourth Quarter 2021 Revenue CARLSBAD, CA. (January 10, 2022) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today preliminary financial results for the fourth quarter and

December 14, 2021 EX-99.1

SeaSpine Appoints Seasoned Healthcare Executive to its Board of Directors

Exhibit 99.1 SeaSpine Appoints Seasoned Healthcare Executive to its Board of Directors CARLSBAD, CA / December 14, 2021 ? SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today that it has appointed Angela Steinway to its Board of Directors, effective December 14, 2021. Ms. Steinway will

December 14, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): December 14, 2021 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

November 3, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NO.

October 28, 2021 EX-99.1

SeaSpine Reports Third Quarter 2021 Financial Results Provides Financial Outlook for Fourth Quarter 2021

Exhibit 99.1 SeaSpine Reports Third Quarter 2021 Financial Results Provides Financial Outlook for Fourth Quarter 2021 CARLSBAD, CA (October 28, 2021) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, today announced financial results for the three-months ended September 30, 2021. Summary of Third

October 28, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): October 28, 2021 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

September 24, 2021 8-K

Regulation FD Disclosure, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): September 24, 2021 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

August 9, 2021 CORRESP

August 9, 2021

August 9, 2021 Via EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, NE Washington, DC 20549-4561 Attn: Mr.

August 5, 2021 EX-10.4

Beau Standish Letter Agreement, dated May 22, 2021

Exhibit 10.4 Dear 7D Team Member, It?s with great pride that we welcome you to the SeaSpine family! Through our strategic partnership, we were able to appreciate the unique alignment of the respective vision and culture of our two organizations. This led to deepening our collaboration to come together as one team committed to advancing and improving surgery with a steadfast focus on safety and pat

August 5, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NO.

August 5, 2021 EX-10.2

Amendment Agreement to the Arrangement Agreement

Exhibit 10.2 AMENDMENT AGREEMENT Dated May 19, 2021 Reference is made to the Arrangement Agreement among SeaSpine Holdings Corporation (?Parent?), Project Maple Leaf Acquisition ULC (?Purchaser?), 7D Surgical Inc. (the ?Company?) and Michael Cadotte and Joel Rose in their capacity as shareholder representatives (the ?Shareholder Representatives?) dated March 22, 2021 (the ?Arrangement Agreement?).

August 5, 2021 EX-10.3

Consent and Agreement Under Amended and Restated Credit Agreement, dated May 20, 2021, among Wells Fargo Bank, National Association, and SeaSpine Holdings Corporation, SeaSpine Orthopedics Corporation, SeaSpine, Inc., Isotis Inc., SeaSpine Sales LLC, Theken Spine, LLC, and Isotis Orthobiologics, Inc.

Exhibit 10.3 CONSENT AND AGREEMENT UNDER AMENDED AND RESTATED CREDIT AGREEMENT CONSENT AND AGREEMENT UNDER AMENDED AND RESTATED CREDIT AGREEMENT (this ?Agreement?) is made as of May 20, 2021, by and among WELLS FARGO BANK, NATIONAL ASSOCIATION, a national banking association, as administrative agent for each member of the Lender Group and the Bank Product Providers (in such capacity, together with

August 5, 2021 S-3

As filed with the Securities and Exchange Commission on August 5, 2021

As filed with the Securities and Exchange Commission on August 5, 2021 Registration No.

August 2, 2021 EX-99.1

SeaSpine Reports Second Quarter 2021 Financial Results Announces Record Quarterly Revenue Updates 2021 Financial Outlook; Raises Bottom End of Guidance Range

Exhibit 99.1 SeaSpine Reports Second Quarter 2021 Financial Results Announces Record Quarterly Revenue Updates 2021 Financial Outlook; Raises Bottom End of Guidance Range CARLSBAD, CA (August 2, 2021) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, today announced financial results for the thre

August 2, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): August 2, 2021 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

July 28, 2021 EX-99.1

Notes to consolidated financial statements

EXHIBIT 99.1 Disclaimer Ernst & Young LLP (EY) prepared the attached Report only for Client pursuant to an agreement solely between EY and Client. EY did not perform its services on behalf of or to serve the needs of any other person or entity. Accordingly, EY expressly disclaims any duties or obligations to any other person or entity based on its use of the attached Report. Any other person or en

July 28, 2021 8-K/A

Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K/A (Amendment No.

July 28, 2021 EX-99.2

SEASPINE HOLDINGS CORPORATION UNAUDITED PRO FORMA COMBINED FINANCIAL STATEMENTS

EXHIBIT 99.2 SEASPINE HOLDINGS CORPORATION UNAUDITED PRO FORMA COMBINED FINANCIAL STATEMENTS On May 20, 2021, SeaSpine Holdings Corporation (the "Company"), announced the closing of the previously announced acquisition (the "Transaction") of 7D Surgical Inc. (the "7D"), a Toronto-based company that develops advanced optical technologies and machine vision-based registration algorithms to improve s

June 14, 2021 S-8

As filed with the Securities and Exchange Commission on June 14, 2021

As filed with the Securities and Exchange Commission on June 14, 2021 Registration No.

June 4, 2021 EX-3.2

Amended and Restated Bylaws, as amended to date

Exhibit 3.2 AMENDED AND RESTATED BYLAWS OF SEASPINE HOLDINGS CORPORATION (As amended as of June 2, 2021) ARTICLE I Meetings of Stockholders Section 1.1. Annual Meetings. The annual meeting of the stockholders of SeaSpine Holdings Corporation (the ?Corporation?) for the election of directors (each, a ?Director?) and for the transaction of such other business as properly may come before such meeting

June 4, 2021 EX-3.1

Certificate of Amendment to Amended and Restated Certificate of Incorporation dated June 2, 2021

Exhibit 3.1 CERTIFICATE OF AMENDMENT OF AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF SEASPINE HOLDINGS CORPORATION SeaSpine Holdings Corporation (the "Corporation"), a corporation organized and existing under the General Corporation Law of the State of Delaware, hereby certifies as follows: 1.This Certificate of Amendment (the "Certificate of Amendment") amends the provisions of the Corpor

June 4, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): June 2, 2021 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

May 21, 2021 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits, Completion of Acquisition or Disposition of Assets

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 20, 2021 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commiss

May 14, 2021 SD

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD Specialized Disclosure Report SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdict

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD Specialized Disclosure Report SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (IRS Employer Identification No.) 5770 Armada Drive, Carlsbad, California 92008 (Address of principal e

May 7, 2021 DEFA14A

- DEFA14A

SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ? Filed by a Party other than the Registrant o Check the appropriate box: oPreliminary Proxy Statement oConfidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) oDefinitive Proxy Statement ?Definitive Additional Materials oSoliciting Material under ?240.

May 3, 2021 EX-99.1

SeaSpine Reports First Quarter 2021 Financial Results Reaffirms 2021 Financial Outlook

EX-99.1 2 spne8-kq12021exhibit991.htm EX-99.1 Exhibit 99.1 SeaSpine Reports First Quarter 2021 Financial Results Reaffirms 2021 Financial Outlook CARLSBAD, CA (May 3, 2021) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, today announced financial results for the three-months ended March 31, 202

May 3, 2021 EX-10.1

Supply Agreement between SeaSpine Orthopedics Corporation and PcoMed, LLC, dated March 1, 2021 (filed as an exhibit to the Quarterly Report on Form 10-Q for the quarter ended March 31, 2021 by SeaSpine Holdings Corporation and incorporated herein by reference).

Exhibit 10.1 CERTAIN CONFIDENTIAL PORTIONS OF THIS EXHIBIT HAVE BEEN OMITTED AND REPLACED WITH ?[***]?. SUCH IDENTIFIED INFORMATION HAS BEEN EXCLUDED FROM THIS EXHIBIT BECAUSE IT IS (I) NOT MATERIAL AND (II) WOULD LIKELY CAUSE COMPETITIVE HARM TO THE COMPANY IF DISCLOSED. SUPPLY AGREEMENT THIS SUPPLY AGREEMENT (this ?Agreement?), effective March 1, 2021 (the ?Effective Date?), is by and between Se

May 3, 2021 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2021 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NO.

May 3, 2021 EX-10.2

Amended and Restated Non-Employee Director Compensation Program, effective June 2, 2020

EX-10.2 3 spne20210331excompprogram.htm EX-10.2 Exhibit 10.2 SEASPINE HOLDINGS CORPORATION NON-EMPLOYEE DIRECTOR COMPENSATION PROGRAM Amended and Restated Effective June 2, 2021 This SeaSpine Holdings Corporation (the “Company”) Non-Employee Director Compensation Program (this “Program”) for non-employee directors (the “Directors”) of the board of directors of the Company (the “Board”) shall be ef

May 3, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 3, 2021 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

April 21, 2021 DEF 14A

Second Amendment to the SeaSpine Holdings Corporation 2015 Employee Stock Purchase Plan (December 9, 2020)

SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: oPreliminary Proxy Statement oConfidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) xDefinitive Proxy Statement oDefinitive Additional Materials oSoliciting Material under ?240.

April 21, 2021 DEFA14A

- DEFA14A

SCHEDULE 14A INFORMATION (Rule 14a-101)PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: oPreliminary Proxy Statement oConfidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) oDefinitive Proxy Statement ?Definitive Additional Materials oSoliciting Material under ?240.

April 19, 2021 EX-1.1

Underwriting Agreement, dated April 15, 2021, by and among SeaSpine Holdings Corporation, Piper Sandler & Co., Canaccord Genuity LLC, and Stifel, Nicolaus & Company

EX-1.1 2 d167794dex11.htm EX-1.1 Exhibit 1.1 Execution Version SeaSpine Holdings Corporation 4,500,000 Shares of Common Stock UNDERWRITING AGREEMENT Dated: April 15, 2021 TABLE OF CONTENTS Page SECTION 1. Representations and Warranties 2 SECTION 2. Sale and Delivery to Underwriters; Closing 17 SECTION 3. Covenants of the Company 19 SECTION 4. Payment of Expenses 23 SECTION 5. Conditions of Underwr

April 19, 2021 EX-99.1

SeaSpine Commences Public Offering of Common Stock

EX-99.1 4 d167794dex991.htm EX-99.1 Exhibit 99.1 SeaSpine Commences Public Offering of Common Stock CARLSBAD, CA. (April 15, 2021) – SeaSpine Holdings Corporation (NASDAQ: SPNE) (“SeaSpine” or the “Company”), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today that it has commenced an underwritten public offering of shares of its

April 19, 2021 424B5

The date of this prospectus supplement is April 15, 2021

Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-236802 PROSPECTUS SUPPLEMENT (To Prospectus Dated February 4, 2021) SeaSpine Holdings Corporation 4,500,000 Shares Common Stock We are offering 4,500,000 shares of our common stock. Our common stock trades on The Nasdaq Global Select Market under the symbol ?SPNE.? On April 15, 2021, the last sale price of the common stock rep

April 19, 2021 EX-99.2

April 15, 2021

Exhibit 99.2 April 15, 2021 SeaSpine Prices Public Offering of Common Stock CARLSBAD, CA. (April 15, 2021) ? SeaSpine Holdings Corporation (NASDAQ: SPNE) (?SeaSpine? or the ?Company?), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, today announced the pricing of its previously announced underwritten public offering of 4,500,000 shares of it

April 19, 2021 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 15, 2021 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commi

April 15, 2021 424B5

SUBJECT TO COMPLETION, DATED April 15, 2021

Table of Contents The information in this preliminary prospectus supplement is not complete and may be changed.

April 9, 2021 PRE 14A

- PRE 14A

SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ? Filed by a Party other than the Registrant o Check the appropriate box: ?Preliminary Proxy Statement oConfidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) oDefinitive Proxy Statement oDefinitive Additional Materials oSoliciting Material under ?240.

April 5, 2021 EX-99.1

SeaSpine Announces Preliminary Results for First Quarter 2021 and Increases 2021 Revenue Guidance Provides Additional Financial Guidance for Pending Acquisition of 7D Surgical

Exhibit 99.1 SeaSpine Announces Preliminary Results for First Quarter 2021 and Increases 2021 Revenue Guidance Provides Additional Financial Guidance for Pending Acquisition of 7D Surgical CARLSBAD, CA. (April 5, 2021) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today preliminary

April 5, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): April 5, 2021 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

April 1, 2021 EX-99.1

SeaSpine Appoints Google Executive and Healthcare Thought Leader to its Board of Directors

EX-99.1 2 spnemaniarappointmentex991.htm EX-99.1 Exhibit 99.1 SeaSpine Appoints Google Executive and Healthcare Thought Leader to its Board of Directors CARLSBAD, CA / April 1, 2021 – SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, today announced that it has appointed Shweta Singh Maniar to its

April 1, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 31, 2021 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

March 24, 2021 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 22, 2021 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commi

March 24, 2021 EX-10.1

Arrangement Agreement, dated March 22, 2021, by and among SeaSpine Holdings Corporation, 7D Surgical Inc. and Project Maple Leaf Acquisition ULC

EX-10.1 2 d96361dex101.htm EX-10.1 Exhibit 10.1 CERTAIN CONFIDENTIAL PORTIONS OF THIS EXHIBIT HAVE BEEN OMITTED AND REPLACED WITH “[***]”. SUCH IDENTIFIED INFORMATION HAS BEEN EXCLUDED FROM THIS EXHIBIT BECAUSE IT IS (I) NOT MATERIAL AND (II) WOULD LIKELY CAUSE COMPETITIVE HARM TO THE COMPANY IF DISCLOSED. SEASPINE HOLDINGS CORPORATION as Parent - and - PROJECT MAPLE LEAF ACQUISITION ULC as Purcha

March 22, 2021 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 22, 2021 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commi

March 22, 2021 EX-99.1

Forward-looking Statements & Disclaimer This presentation includes statements that may be forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. The words “believe,” “estimate,” “expect,” “anticipate,”

Exhibit 99.1 SeaSpine + 7D Surgical A Powerful Combination: Accessing the Full Continuum of Care Keith C. Valentine Beau Standish, PEng, PhD President & Chief Executive Officer Chief Executive Officer ?2021 SeaSpine Orthopedics Corporation. All rights reserved. 1Exhibit 99.1 SeaSpine + 7D Surgical A Powerful Combination: Accessing the Full Continuum of Care Keith C. Valentine Beau Standish, PEng,

March 5, 2021 EX-10.18(B)

Amendment 10 to the Supply Agreement between SeaSpine Orthopedics Corporation and PcoMed, LLC

Exhibit 10.18(b) AMENDMENT NO. 10 TO SUPPLY AGREEMENT This Amendment No. 10 to Supply Agreement (this “Amendment”) is entered into effective as of December 1, 2020 (the “Effective Date”) by and between SeaSpine Orthopedics Corporation, a Delaware corporation (“SeaSpine”), and PcoMed, LLC, a Colorado limited liability company (“PcoMed”). WHEREAS, SeaSpine and PcoMed are parties to a certain Supply

March 5, 2021 10-K

Annual Report - 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2020 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NO.

March 1, 2021 EX-99.1

SeaSpine Announces Fourth Quarter and Full-Year 2020 Results Reports Record Quarterly Revenue, Driven by U.S. Sales Channel

Exhibit 99.1 SeaSpine Announces Fourth Quarter and Full-Year 2020 Results Reports Record Quarterly Revenue, Driven by U.S. Sales Channel CARLSBAD, CA (March 1, 2021) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today financial results for the three-months and full-year ended Decemb

March 1, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 1, 2021 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

February 16, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 6)* SEASPINE HOLDINGS CORPORATION (Name of Issuer) Common Stock, $0.01 par value per share (Title of Class o

SC 13G/A 1 tm216525d2sc13ga.htm SCHEDULE 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 6)* SEASPINE HOLDINGS CORPORATION (Name of Issuer) Common Stock, $0.01 par value per share (Title of Class of Securities) 81255T 108 (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of this

February 3, 2021 S-3/A

- S-3/A

As filed with the Securities and Exchange Commission on February 3, 2021 Registration No.

February 2, 2021 CORRESP

-

February 2, 2021 Via EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, NE Washington, DC 20549-4561 Attn: Mr.

February 2, 2021 S-3/A

- S-3/A

S-3/A 1 s-3a2021february.htm S-3/A As filed with the Securities and Exchange Commission on February 2, 2021 Registration No. 333-236802 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 AMENDMENT NO. 1 TO FORM S-3 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SeaSpine Holdings Corporation (Exact Name of Registrant as Specified in Its Charter) Delaware 5770 Armada Dr

January 29, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): January 28, 2021 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

January 29, 2021 EX-10.1

SeaSpine Holdings Corporation Amended and Restated 2015 Incentive Award Plan Annual Incentive Program

EX-10.1 2 a2015plan-annualincentivep.htm EX-10.1 Exhibit 10.1 SEASPINE HOLDINGS CORPORATION AMENDED AND RESTATED 2015 INCENTIVE AWARD PLAN ANNUAL INCENTIVE PROGRAM (beginning January 1, 2019) This Annual Incentive Program (beginning January 1, 2019) (hereinafter referred to as the “Program”) is hereby adopted under Section 9.1(b) the SeaSpine Holdings Corporation (the “Company”) Amended and Restat

January 11, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): January 11, 2021 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

January 11, 2021 EX-99.1

SeaSpine Announces Preliminary Results and Record Quarterly Revenue, Driven by U.S. Sales Channel

EX-99.1 2 q420exhibit991prelimresults.htm EX-99.1 EXHIBIT 99.1 SeaSpine Announces Preliminary Results and Record Quarterly Revenue, Driven by U.S. Sales Channel CARLSBAD, CA. (January 11, 2021) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today preliminary financial results for the

January 8, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934*

SC 13G/A 1 spne-sc13ga010821.htm AMENDED ACQUISITION OF BENEFICIAL OWNERSHIP UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934* SeaSpine Holdings Corporation (Name of Issuer) Common Stock, $0.01 par value (Title of Class of Securities) 81255T108 (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of th

December 30, 2020 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* SeaSpine Holdings Corp (Name of Issuer) Common Stock (Title of class of securities) (CUSIP number) Decem

SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* SeaSpine Holdings Corp (Name of Issuer) Common Stock (Title of class of securities) 81255T108 (CUSIP number) December 30, 2020 (Date of event which requires filing of this statement) Check the appropriate box to designate the rule pursuant to wh

December 29, 2020 8-K

Entry into a Material Definitive Agreement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): December 21, 2020 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

December 11, 2020 EX-3.1

Amended and Restated Bylaws, as amended to date

EX-3.1 2 bylawamendment2020.htm EX-3.1 Exhibit 3.1 AMENDED AND RESTATED BYLAWS OF SEASPINE HOLDINGS CORPORATION (As amended as of February 28, 2019December 9, 2020) ARTICLE I Meetings of Stockholders Section 1.1. Annual Meetings. The annual meeting of the stockholders of SeaSpine Holdings Corporation (the “Corporation”) for the election of directors (each, a “Director”) and for the transaction of

December 11, 2020 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): December 9, 2020 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

November 9, 2020 EX-99.1

SeaSpine Reports Third Quarter 2020 Financial Results

Exhibit 99.1 SeaSpine Reports Third Quarter 2020 Financial Results CARLSBAD, CA (November 9, 2020) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, today announced financial results for the three-months ended September 30, 2020. Summary of Third Quarter 2020 Financial Results and Recent Accompli

November 9, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): November 9, 2020 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

November 9, 2020 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2020 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NO.

October 6, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): October 6, 2020 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

October 6, 2020 EX-99.1

SeaSpine Provides Preliminary Results for Third Quarter 2020 and Revenue Guidance for Fourth Quarter 2020

Exhibit 99.1 SeaSpine Provides Preliminary Results for Third Quarter 2020 and Revenue Guidance for Fourth Quarter 2020 CARLSBAD, CA. (October 6, 2020) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today preliminary financial results for the third quarter of 2020 and provided a reven

August 27, 2020 CORRESP

-

August 27, 2020 Via EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, NE Washington, DC 20549-4561 Attn: Ms.

August 27, 2020 S-3/A

- S-3/A

S-3/A 1 s-3a2020nlt.htm S-3/A As filed with the Securities and Exchange Commission on August 27, 2020 Registration No. 333-248136 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 AMENDMENT NO. 1 TO FORM S-3 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SeaSpine Holdings Corporation (Exact Name of Registrant as Specified in Its Charter) Delaware 5770 Armada Drive Ca

August 27, 2020 CORRESP

-

DLA Piper LLP (US) 4365 Executive Drive, Suite 1100 San Diego, California 92121-2133 www.

August 19, 2020 S-3

- S-3

S-3 1 s-32020nlt.htm S-3 As filed with the Securities and Exchange Commission on August 19, 2020 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-3 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SeaSpine Holdings Corporation (Exact Name of Registrant as Specified in Its Charter) Delaware 5770 Armada Drive Carlsbad, CA 92008 (760) 727-839

August 4, 2020 S-8

- S-8

As filed with the Securities and Exchange Commission on August 4, 2020 Registration No.

August 4, 2020 EX-10.1

Consent Under and First Amendment to Amended and Restated Credit Agreement

EXHIBIT 10.1 CONSENT UNDER AND FIRST AMENDMENT TO AMENDED AND RESTATED CREDIT AGREEMENT THIS CONSENT UNDER AND FIRST AMENDMENT TO AMENDED AND RESTATED CREDIT AGREEMENT (this “Amendment”) is made as of April 24, 2020, by and among WELLS FARGO BANK, NATIONAL ASSOCIATION, a national banking association, as administrative agent for each member of the Lender Group and the Bank Product Providers (in suc

August 4, 2020 EX-99.1

SeaSpine Reports Second Quarter 2020 Financial Results

Exhibit 99.1 SeaSpine Reports Second Quarter 2020 Financial Results CARLSBAD, CA (August 4, 2020) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, today announced financial results for the three months ended June 30, 2020. Summary of Second Quarter 2020 Financial Results and Recent Accomplishmen

August 4, 2020 EX-10.5

SeaSpine Holdings Corporation 2020 Employment Inducement Incentive Award Plan

EXHIBIT 10.5 SEASPINE HOLDINGS CORPORATION 2020 EMPLOYMENT INDUCEMENT INCENTIVE AWARD PLAN ARTICLE 1. PURPOSE The purpose of the SeaSpine Holdings Corporation 2020 Employment Inducement Incentive Award Plan (the “Plan”) is to promote the success and enhance the value of SeaSpine Holdings Corporation, a Delaware corporation (the “Company”), by linking the individual interests of Eligible Individual

August 4, 2020 EX-10.6

Form of 2020 Employment Inducement Incentive Award Plan Restricted Stock Unit Award Grant Notice and Restricted Stock Unit Award Agreement under the SeaSpine Holdings Corporation 2020 Employment Inducement Incentive Award Plan

EXHIBIT 10.6 SEASPINE HOLDINGS CORPORATION 2020 EMPLOYMENT INDUCEMENT INCENTIVE AWARD PLAN RESTRICTED STOCK UNIT AWARD GRANT NOTICE AND RESTRICTED STOCK UNIT AWARD AGREEMENT SeaSpine Holdings Corporation, a Delaware corporation (the “Company”), pursuant to its 2020 Employment Inducement Incentive Award Plan (as may be amended and/or restated from time to time, the “Plan”), hereby grants to the ind

August 4, 2020 EX-10.8

Form of Stock Option Grant Notice and Stock Option Agreement under the SeaSpine Holdings Corporation 2020 Employment Inducement Incentive Award Plan (for Non-Senior Leadership Team Members)

EXHIBIT 10.8 SEASPINE HOLDINGS CORPORATION 2020 EMPLOYMENT INDUCEMENT INCENTIVE AWARD PLAN STOCK OPTION GRANT NOTICE SeaSpine Holdings Corporation, a Delaware corporation (the “Company”), pursuant to its 2020 Employment Inducement Incentive Award Plan (as may be amended and/or restated from time to time, the “Plan”), hereby grants to the individual listed below (the “Optionee”), an option to purch

August 4, 2020 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2020 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NO.

August 4, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): August 4, 2020 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001- 36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

August 4, 2020 EX-10.7

Form of Stock Option Grant Notice and Stock Option Agreement under the SeaSpine Holdings Corporation 2020 Employment Inducement Incentive Award Plan (for Senior Leadership Team Members)

EXHIBIT 10.7 SEASPINE HOLDINGS CORPORATION 2020 EMPLOYMENT INDUCEMENT INCENTIVE AWARD PLAN STOCK OPTION GRANT NOTICE SeaSpine Holdings Corporation, a Delaware corporation (the “Company”), pursuant to its 2020 Employment Inducement Incentive Award Plan (as may be amended and/or restated from time to time, the “Plan”), hereby grants to the individual listed below (the “Optionee”), an option to purch

July 31, 2020 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): July 30, 2020 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001- 36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

July 31, 2020 EX-10.1

Second Amendment to Amended and Restated Credit Agreement made as of July 30, 2020 by and among Wells Fargo Bank, N.A., as administrative agent for each member of the lender group and the bank product providers, the lenders party thereto, SeaSpine Holdings Corporation, SeaSpine Orthopedics Corporation, SeaSpine, Inc., ISOTIS, Inc., SeaSpine Sales LLC, Theken Spine, LLC, and IsoTis Orthobiologics, Inc.

Exhibit 10.1 SECOND AMENDMENT TO AMENDED AND RESTATED CREDIT AGREEMENT THIS SECOND AMENDMENT TO AMENDED AND RESTATED CREDIT AGREEMENT (this “Amendment”) is made as of July 30, 2020, by and among WELLS FARGO BANK, NATIONAL ASSOCIATION, a national banking association, as administrative agent for each member of the Lender Group and the Bank Product Providers (in such capacity, together with its succe

June 5, 2020 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): June 3, 2020 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001- 36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

May 15, 2020 SD

- SD

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD Specialized Disclosure Report SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (IRS Employer Identification No.) 5770 Armada Drive, Carlsbad, California 92008 (Address of principal e

May 6, 2020 EX-99.1

SeaSpine Reports First Quarter 2020 Financial Results

Exhibit 99.1 SeaSpine Reports First Quarter 2020 Financial Results CARLSBAD, CA (May 6, 2020) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, today announced financial results for the three-months ended March 31, 2020. Summary of First Quarter 2020 Financial Results and Recent Accomplishments •

May 6, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

8-K 1 spne8-kq12020earningsrelea.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 6, 2020 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001- 36905 47-3251758 (State or other

May 6, 2020 10-Q

Quarterly Report - 10-Q

10-Q 1 spne2020033110-q.htm 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2020 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION F

April 24, 2020 EX-10.1

Letter agreement dated April 23, 2020 with Keith C. Valentine

Exhibit 10.1 April 23, 2020 Reference is made to that certain Employment Agreement, between SeaSpine Holdings Corporation, a Delaware corporation, SeaSpine Orthopedics Corporation, a Delaware corporation, and Keith Valentine (“Executive”) entered into and effective as of April 28, 2015, as amended pursuant to that certain Amendment to Employment Agreement, entered into and effective as of April 30

April 24, 2020 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): April 23, 2020 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001- 36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

April 24, 2020 EX-10.2

Form of letter agreement dated April 23, 2020 with members of the senior leadership team of SeaSpine Holdings Corporation other than Keith C. Valentine

Exhibit 10.2 April 23, 2020 Reference is made to that certain Senior Leadership Retention and Severance Plan (effective January 27, 2016, with Exhibit A updated as of August 22, 2018) (the “Plan”). The undersigned (“Participant”) hereby consents to a reduction in Participant’s base salary equal to 25% of Participant’s base salary on the date set forth above, which reduction will be effective begin

April 20, 2020 DEF 14A

Amendment to the SeaSpine Holdings Corporation Amended and Restated 2015 Incentive Award Plan (effective June 3, 2020)

SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ý Filed by a Party other than the Registrant o Check the appropriate box: oPreliminary Proxy Statement oConfidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ýDefinitive Proxy Statement oDefinitive Additional Materials oSoliciting Material under §240.

April 20, 2020 DEFA14A

SPNE / SeaSpine Holdings Corporation DEFA14A - - DEFA14A

DEFA14A 1 a2020spnedefa14a.htm DEFA14A SCHEDULE 14A INFORMATION (Rule 14a-101)PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: oPreliminary Proxy Statement oConfidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) oDefinitive Proxy Statement ýDefi

April 6, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): April 6, 2020 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001- 36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

April 6, 2020 EX-99.1

SeaSpine Provides Preliminary Results for First Quarter 2020 and COVID-19 Related Business Update Strong Cash Position of Approximately $105 Million Provides Operational Stability Company Withdraws Guidance for 2020

Exhibit 99.1 SeaSpine Provides Preliminary Results for First Quarter 2020 and COVID-19 Related Business Update Strong Cash Position of Approximately $105 Million Provides Operational Stability Company Withdraws Guidance for 2020 CARLSBAD, CA. (April 6, 2020) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal

February 28, 2020 EX-4.4

Form of Indenture for Subordinated Debt Securities

EX-4.4 3 exhibit44-formsubordinated.htm EXHIBIT 4.4 Exhibit 4.4 SEASPINE HOLDINGS CORPORATION, ISSUER AND [TRUSTEE], TRUSTEE INDENTURE DATED AS OF , 20 SUBORDINATED DEBT SECURITIES TABLE OF CONTENTS Page ARTICLE 1 DEFINITIONS 1 Section 1.01 Definitions of Terms 1 ARTICLE 2 ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 4 Section 2.01 Designation and Terms of Securiti

February 28, 2020 S-3

SPNE / SeaSpine Holdings Corporation S-3 - - S-3

As filed with the Securities and Exchange Commission on February 28, 2020 Registration No.

February 28, 2020 10-K

SPNE / SeaSpine Holdings Corporation 10-K - Annual Report - 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2019 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NO.

February 28, 2020 EX-10.12I

SeaSpine Holdings Corporation Amended and Restated 2015 Incentive Award Plan - Form of Restricted Stock Unit Award Grant Notice and Restricted Stock Unit Award Agreement. (used for grants on and after January 1, 2020)

EXHIBIT 10.12(i) SEASPINE HOLDINGS CORPORATION 2015 INCENTIVE AWARD PLAN RESTRICTED STOCK AWARD GRANT NOTICE AND RESTRICTED STOCK AWARD AGREEMENT SeaSpine Holdings Corporation, a Delaware corporation (the “Company”), pursuant to its 2015 Incentive Award Plan (as may be amended and/or restated from time to time, the “Plan”), hereby grants to the individual listed below (the “Participant”), an award

February 28, 2020 EX-4.3

Form of Senior Indenture

Exhibit 4.3 SEASPINE HOLDINGS CORPORATION, ISSUER AND [TRUSTEE], TRUSTEE INDENTURE DATED AS OF , 20 SENIOR DEBT SECURITIES TABLE OF CONTENTS Page ARTICLE I DEFINITIONS 1 Section 1.1 Definitions of Terms 1 ARTICLE II ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 4 Section 2.1 Designation and Terms of Securities 4 Section 2.2 Form of Securities and Trustee’s Certifica

February 28, 2020 EX-4.4

Description of securities of the registrant

EXHIBIT 4.4 DESCRIPTION OF THE REGISTRANT’S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 As of February 21, 2020, SeaSpine Holdings Corporation (the "Company," "we," "our" and "us") had one classes of securities registered under Section 12 of the Securities Exchange Act of 1934 (the “Exchange Act”): common stock, $0.01 par value per share (“common stock”). Ge

February 26, 2020 EX-99.1

SeaSpine Announces Fourth Quarter and Full-Year 2019 Results and Reaffirms 2020 Revenue Guidance

Exhibit 99.1 SeaSpine Announces Fourth Quarter and Full-Year 2019 Results and Reaffirms 2020 Revenue Guidance CARLSBAD, CA (February 26, 2020) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today financial results for the three-months and full-year ended December 31, 2019 and reaffir

February 26, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): February 26, 2020 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001- 36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

February 14, 2020 SC 13G/A

SPNE / SeaSpine Holdings Corporation / First Light Asset Management, LLC - AMENDMENT TO FORM SC 13G Passive Investment

SC 13G/A 1 spne-sc13ga021220.htm AMENDMENT TO FORM SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934* SeaSpine Holdings Corporation (Name of Issuer) Common Stock, $0.01 par value (Title of Class of Securities) 81255T108 (CUSIP Number) December 31, 2019 (Date of Event Which Requires Filing of this Statement) Check

February 11, 2020 EX-99.1

Group Members Richard E. Caruso, Ph.D. Tru St Partnership LP Provco Leasing Corporation The Uncommon Individual Foundation

Exhibit 99.1 Group Members Richard E. Caruso, Ph.D. Tru St Partnership LP Provco Leasing Corporation The Uncommon Individual Foundation

February 11, 2020 EX-99.2

JOINT FILING AGREEMENT

Exhibit 99.2 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of a Statement on Schedule 13G (including amendments thereto) with respect to the common stock, par value $0.01 per share of SeaSpine Holdings Corporation, and further agree that this Joint Filing Agr

February 11, 2020 SC 13G/A

SPNE / SeaSpine Holdings Corporation / CARUSO RICHARD E - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 5)* SEASPINE HOLDINGS CORPORATION (Name of Issuer) Common Stock, $0.01 par value per share (Title of Class of Securities) 81255T 108 (CUSIP Number) December 31, 2019 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designa

February 5, 2020 SC 13G/A

SPNE / SeaSpine Holdings Corporation / Novo A/S - AMENDMENT NO. 2 TO SCHEDULE 13G Passive Investment

Amendment No. 2 to Schedule 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* SeaSpine Holdings Corp (Name of Issuer) Common Stock (Title of class of securities) 81255T108 (CUSIP number) December 31, 2019 (Date of event which requires filing of this statement) Check the appropriate box to designate

January 28, 2020 SC 13G

SPNE / SeaSpine Holdings Corporation / FALCON POINT CAPITAL, LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Seaspine Holdings Corp. (Name of Issuer) Common Stock (Title of Class of Securities) 81255T108 (CUSIP Number) December 31, 2019 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this

January 9, 2020 SC 13G/A

SPNE / SeaSpine Holdings Corporation / First Light Asset Management, LLC - AMENDMENT TO FORM SC 13G Passive Investment

SC 13G/A 1 spne-sc13ga010820.htm AMENDMENT TO FORM SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934* SeaSpine Holdings Corporation (Name of Issuer) Common Stock, $0.01 par value (Title of Class of Securities) 81255T108 (CUSIP Number) January 8, 2020 (Date of Event Which Requires Filing of this Statement) Check t

January 8, 2020 EX-99.2

January 7, 2020

EX-99.2 Exhibit 99.2 January 7, 2020 SeaSpine Prices Public Offering of Common Stock CARLSBAD, CA. (January 7, 2020) – SeaSpine Holdings Corporation (NASDAQ: SPNE) (“SeaSpine” or the “Company”), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, today announced the pricing of its previously announced underwritten public offering of 6,800,000 sh

January 8, 2020 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Other Events

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 7, 2020 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (

January 8, 2020 424B5

The date of this prospectus supplement is January 7, 2020

424B5 Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-230047 PROSPECTUS SUPPLEMENT (To Prospectus Dated May 22, 2019) SeaSpine Holdings Corporation 6,800,000 Shares Common Stock We are offering 6,800,000 shares of our common stock. Our common stock trades on The Nasdaq Global Market under the symbol “SPNE.” On January 7, 2020, the last sale price of the common stock reporte

January 8, 2020 EX-99.1

January 7, 2020

EX-99.1 Exhibit 99.1 January 7, 2020 SeaSpine Commences Public Offering of Common Stock CARLSBAD, CA. (January 7, 2020) – SeaSpine Holdings Corporation (NASDAQ: SPNE) (“SeaSpine” or the “Company”), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today that it has commenced an underwritten public offering of shares of its common sto

January 8, 2020 EX-1.1

Underwriting Agreement, dated January 7, 2020, by and among SeaSpine Holdings Corporation, Piper Sandler & Co. and Canaccord Genuity LLC

EX-1.1 Exhibit 1.1 Execution Version SeaSpine Holdings Corporation 6,800,000 Shares of Common Stock UNDERWRITING AGREEMENT Dated: January 7, 2020 TABLE OF CONTENTS Page SECTION 1. Representations and Warranties 2 SECTION 2. Sale and Delivery to Underwriters; Closing 16 SECTION 3. Covenants of the Company 17 SECTION 4. Payment of Expenses 21 SECTION 5. Conditions of Underwriters’ Obligations 22 SEC

January 7, 2020 424B5

SUBJECT TO COMPLETION, DATED JANUARY 7, 2020

424B5 Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-230047 The information in this preliminary prospectus supplement is not complete and may be changed. Neither this preliminary prospectus supplement nor the accompanying prospectus is an offer to sell these securities, and we are not soliciting an offer to buy these securities, in any jurisdiction where the offer or sale

January 7, 2020 EX-99.1

SeaSpine Announces Preliminary Results for Fourth Quarter and Full-Year 2019; Reports Record Revenue, Driven by Greater Than 20% U.S. Spinal Implants Growth Provides Revenue Guidance for 2020

EX-99.1 2 d861804dex991.htm EX-99.1 Exhibit 99.1 SeaSpine Announces Preliminary Results for Fourth Quarter and Full-Year 2019; Reports Record Revenue, Driven by Greater Than 20% U.S. Spinal Implants Growth Provides Revenue Guidance for 2020 CARLSBAD, CA. (January 7, 2020)—SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatme

January 7, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 7, 2020 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (

October 29, 2019 10-Q

September 30, 2019

10-Q 1 spne2019093010-q.htm 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2019 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSI

October 29, 2019 EX-96.1

Press release dated October 29, 2019

Exhibit 99.1 SeaSpine Reports Record Revenue, Driven by 16% U.S. Spinal Implants Growth Increases 2019 total revenue guidance to between $157 million and $158 million Implies 10% to 12% growth over fourth quarter 2018 CARLSBAD, CA (October 29, 2019) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorder

October 29, 2019 8-K

Termination of a Material Definitive Agreement, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): October 23, 2019 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001- 36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

August 1, 2019 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): August 1, 2019 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001- 36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

August 1, 2019 EX-99.1

SeaSpine Reports Second Quarter 2019 Financial Results Increases 2019 Financial Outlook

Exhibit 99.1 SeaSpine Reports Second Quarter 2019 Financial Results Increases 2019 Financial Outlook CARLSBAD, CA (Aug 1, 2019) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today financial results for the quarter ended June 30, 2019 and updated its financial outlook for 2019. Summa

August 1, 2019 10-Q

June 30, 2019

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2019 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NO.

May 31, 2019 EX-10.1

Form of Indemnification Agreement entered into between SeaSpine Holdings Corporation and each of its directors and officers

EX-10.1 2 spneexhibit101.htm EXHIBIT 10.1 Exhibit 10.1 INDEMNIFICATION AGREEMENT This Indemnification Agreement (“Agreement”) is made as of [Date] by and between SeaSpine Holdings Corporation, a Delaware corporation (the “Company”), and [Name] (“Indemnitee”). This Agreement supersedes and replaces any and all previous agreements between the Company and Indemnitee covering the subject matter of thi

May 31, 2019 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 29, 2019 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001- 36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

May 17, 2019 SD

SPNE / SeaSpine Holdings Corporation SD SD

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD Specialized Disclosure Report SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001-36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (IRS Employer Identification No.) 5770 Armada Drive, Carlsbad, California 92008 (Address of principal e

May 17, 2019 CORRESP

SPNE / SeaSpine Holdings Corporation CORRESP - -

CORRESP May 17, 2019 Via EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, NE Washington, DC 20549-4561 Attn: Mr.

May 1, 2019 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 1, 2019 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001- 36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

May 1, 2019 EX-99.1

SeaSpine Reports First Quarter 2019 Financial Results Updates 2019 Financial Outlook; Raises Bottom End of Guidance Range

Exhibit 99.1 SeaSpine Reports First Quarter 2019 Financial Results Updates 2019 Financial Outlook; Raises Bottom End of Guidance Range CARLSBAD, CA (May 1, 2019) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today financial results for the quarter ended March 31, 2019 and updated it

May 1, 2019 EX-10.1

Tyler Lipschultz Letter Agreement, dated July 9, 2015

EX-10.1 2 ex101tylerlipschultzofferl.htm EXHIBIT 10.1 Exhibit 10.1 July 9, 2015 Tyler Lipschultz 12590 Cavallo Street San Diego, CA 92139 Dear Tyler: I am delighted to offer you the position of Vice President of Orthobiologics and Business Development for SeaSpine. In this position you will report to me, Keith Valentine, President and CEO for SeaSpine. Your start date is expected on or before Frid

May 1, 2019 10-Q

March 31, 2019

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2019 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NO.

April 30, 2019 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

8-K 1 spne8-kvalentineagreementa.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): April 30, 2019 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001- 36905 47-3251758 (State or oth

April 30, 2019 EX-10.1

Amendment to Employment Agreement entered into effective as of April 30, 2019 by and between SeaSpine Holdings Corporation and SeaSpine Orthopedics Corporation and Keith Valentine

EX-10.1 2 spneexhibit101.htm EXHIBIT 10.1 Exhibit 10.1 AMENDMENT TO EMPLOYMENT AGREEMENT This Amendment to Employment Agreement (this “Amendment”) is entered into effective as of April 30, 2019 by and between SeaSpine Holdings Corporation, a Delaware corporation (“Holdings”), SeaSpine Orthopedics Corporation, a Delaware corporation (“SeaSpine,” and, together with Holdings, the “Company”) and Keith

April 17, 2019 DEFA14A

SPNE / SeaSpine Holdings Corporation DEFA14A

SCHEDULE 14A INFORMATION (Rule 14a-101)PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: oPreliminary Proxy Statement oConfidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) oDefinitive Proxy Statement ýDefinitive Additional Materials oSoliciting Material under §240.

April 17, 2019 DEF 14A

First Amendment to the SeaSpine Holdings Corporation 2015 Employee Stock Purchase Plan

SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ý Filed by a Party other than the Registrant o Check the appropriate box: oPreliminary Proxy Statement oConfidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ýDefinitive Proxy Statement oDefinitive Additional Materials oSoliciting Material under §240.

March 4, 2019 EX-4.4

Form of Indenture for Subordinated Debt Securities

EX-4.4 3 exhibit44-formsubordinated.htm EXHIBIT 4.4 Exhibit 4.4 SEASPINE HOLDINGS CORPORATION, ISSUER AND [TRUSTEE], TRUSTEE INDENTURE DATED AS OF , 20 SUBORDINATED DEBT SECURITIES TABLE OF CONTENTS Page ARTICLE 1 DEFINITIONS 1 Section 1.01 Definitions of Terms 1 ARTICLE 2 ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 4 Section 2.01 Designation and Terms of Securiti

March 4, 2019 EX-4.3

Form of Indenture for Senior Debt Securities

EX-4.3 2 exhibit43-formseniorindent.htm EXHIBIT 4.3 Exhibit 4.3 SEASPINE HOLDINGS CORPORATION, ISSUER AND [TRUSTEE], TRUSTEE INDENTURE DATED AS OF , 20 SENIOR DEBT SECURITIES TABLE OF CONTENTS Page ARTICLE I DEFINITIONS 1 Section 1.1 Definitions of Terms 1 ARTICLE II ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 4 Section 2.1 Designation and Terms of Securities 4 Se

March 4, 2019 S-3

SPNE / SeaSpine Holdings Corporation S-3

As filed with the Securities and Exchange Commission on March 1, 2019 Registration No.

March 1, 2019 424B5

The date of this prospectus supplement is March 1, 2019 Table of Contents

424B5 1 seaspine-atmprospectuscant.htm 424B5 Filed pursuant to Rule 424(b)(5) Registration Statement No. 333-213089 PROSPECTUS SUPPLEMENT (To Prospectus dated August 24, 2016) SeaSpine Holdings Corporation $50,000,000 Common Stock We have entered into a Controlled Equity OfferingSM Sales Agreement, or sales agreement, with Cantor Fitzgerald & Co. relating to our common shares offered by this prosp

March 1, 2019 EX-10.1

Controlled Equity OfferingSM Sales Agreement, dated March 1, 2019, by and between SeaSpine Holdings Corporation and Cantor Fitzgerald & Co.

Exhibit 10.1 SeaSpine Holdings Corporation Shares of Common Stock (par value $0.01 per share) Controlled Equity OfferingSM Sales Agreement March 1, 2019 Cantor Fitzgerald & Co. 499 Park Avenue New York, NY 10022 Ladies and Gentlemen: SeaSpine Holdings Corporation, a Delaware corporation (the “Company”), confirms its agreement (this “Agreement”) with Cantor Fitzgerald & Co. (the “Agent”), as follow

March 1, 2019 8-K

Entry into a Material Definitive Agreement, Termination of a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 1, 2019 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001- 36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

March 1, 2019 EX-3.2

Amended and Restated Bylaws of SeaSpine Holdings Corporation

EXHIBIT 3.2 AMENDED AND RESTATED BYLAWS OF SEASPINE HOLDINGS CORPORATION (As amended as of February 28, 2019) ARTICLE I Meetings of Stockholders Section 1.1. Annual Meetings. The annual meeting of the stockholders of SeaSpine Holdings Corporation (the “Corporation”) for the election of directors (each, a “Director”) and for the transaction of such other business as properly may come before such me

March 1, 2019 10-K

Form 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-K (Mark One) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2018 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NO.

February 28, 2019 EX-3.1

Amended and Restated Bylaws, as amended to date

EXHIBIT 3.1 AMENDED AND RESTATED BYLAWS OF SEASPINE HOLDINGS CORPORATION (As amended as of February 28, 2019) ARTICLE I Meetings of Stockholders Section 1.1. Annual Meetings. The annual meeting of the stockholders of SeaSpine Holdings Corporation (the “Corporation”) for the election of directors (each, a “Director”) and for the transaction of such other business as properly may come before such me

February 28, 2019 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): February 28, 2019 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001- 36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

February 27, 2019 EX-99.1

SeaSpine Announces Fourth Quarter and Full-Year 2018 Results and Reaffirms 2019 Revenue Guidance

Exhibit 99.1 SeaSpine Announces Fourth Quarter and Full-Year 2018 Results and Reaffirms 2019 Revenue Guidance CARLSBAD, CA (February 27, 2019) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today financial results for the three-months and full-year ended December 31, 2018 and reaffir

February 27, 2019 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): February 27, 2019 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001- 36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

February 19, 2019 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): February 19, 2019 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001- 36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

February 19, 2019 EX-99.1

SeaSpine Appoints Kim Commins-Tzoumakas and Renee Gaeta to its Board of Directors

Exhibit 99.1 SeaSpine Appoints Kim Commins-Tzoumakas and Renee Gaeta to its Board of Directors CARLSBAD, CA. (February 19, 2019) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today the appointment of Kim Commins-Tzoumakas and Renee Gaeta as members of the Company’s Board of Director

February 14, 2019 SC 13G/A

SPNE / SeaSpine Holdings Corporation / First Light Asset Management, LLC - AMENDMENT TO FORM SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934* SeaSpine Holdings Corporation (Name of Issuer) Common Stock, $0.01 par value (Title of Class of Securities) 81255T108 (CUSIP Number) December 31, 2018 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to whi

February 11, 2019 EX-99.2

JOINT FILING AGREEMENT

EX-99.2 3 a19-44462ex99d2.htm EX-99.2 Exhibit 99.2 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of a Statement on Schedule 13G (including amendments thereto) with respect to the common stock, par value $0.01 per share of SeaSpine Holdings Corporation, and fu

February 11, 2019 EX-99.1

Group Members Richard E. Caruso, Ph.D. Tru St Partnership LP Provco Leasing Corporation The Uncommon Individual Foundation

Exhibit 99.1 Group Members Richard E. Caruso, Ph.D. Tru St Partnership LP Provco Leasing Corporation The Uncommon Individual Foundation

February 11, 2019 SC 13G/A

SPNE / SeaSpine Holdings Corporation / CARUSO RICHARD E - SC 13G/A Passive Investment

SC 13G/A 1 a19-44462sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 4)* SEASPINE HOLDINGS CORPORATION (Name of Issuer) Common Stock, $0.01 par value per share (Title of Class of Securities) 81255T 108 (CUSIP Number) December 31, 2018 (Date of Event Which Requires Filing of this Stateme

February 1, 2019 SC 13G/A

SPNE / SeaSpine Holdings Corporation / Novo A/S - SC 13G/A Passive Investment

SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* SeaSpine Holdings Corp (Name of Issuer) Common Stock (Title of class of securities) 81255T108 (CUSIP number) December 31, 2018 (Date of event which requires filing of this statement) Check the appropriate box to designate the rule pursuant to wh

January 9, 2019 SC 13G

SPNE / SeaSpine Holdings Corporation / FALCON POINT CAPITAL, LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Seaspine Holdings Corp. (Name of Issuer) Common Stock (Title of Class of Securities) 81255T108 (CUSIP Number) December 31, 2018 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this

January 7, 2019 EX-99.1

SeaSpine Announces Preliminary Results for Fourth Quarter and Full-Year 2018

EX-99.1 2 q418exhibit991.htm EXHIBIT 99.1 EXHIBIT 99.1 SeaSpine Announces Preliminary Results for Fourth Quarter and Full-Year 2018 CARLSBAD, CA. (January 7, 2019) - SeaSpine Holdings Corporation (NASDAQ: SPNE), a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced today preliminary financial results for the fourth quarter and full-year

January 7, 2019 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): January 7, 2019 SeaSpine Holdings Corporation (Exact name of registrant as specified in its charter) Delaware 001- 36905 47-3251758 (State or other jurisdiction of incorporation) (Commission File Number) (I.

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