VINC / Vincerx Pharma, Inc. - Pengajuan SECLaporan Tahunan, Pernyataan Proksi

Vincerx Pharma, Inc.
US ˙ OTCPK

Mga Batayang Estadistika
CIK 1796129
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Vincerx Pharma, Inc.
SEC Filings (Chronological Order)
Halaman ini menyediakan daftar lengkap dan kronologis dari Pengajuan SEC, tidak termasuk pengajuan kepemilikan yang kami sediakan di tempat lain.
July 16, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14AINFORMATION Proxy Statement Pursuant To Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14AINFORMATION Proxy Statement Pursuant To Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☑ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for use of the Commission Only (as permitted by Rul

July 7, 2025 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 30, 2025 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission File

July 7, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 30, 2025 Vincerx Pharma, Inc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 30, 2025 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission File

July 7, 2025 EX-99.1

Vincerx Pharma, Inc. Urges Stockholders to Vote FOR Approval of Dissolution Proposal and Announces Potential Range for Distributions to Stockholders Potential Distribution Range of $0.04 to $0.08 per share of outstanding stock based on current estima

EX-99.1 Exhibit 99.1 Vincerx Pharma, Inc. Urges Stockholders to Vote FOR Approval of Dissolution Proposal and Announces Potential Range for Distributions to Stockholders Potential Distribution Range of $0.04 to $0.08 per share of outstanding stock based on current estimates and assumptions, including timely approval of Distribution Proposal Failure to approve Dissolution Proposal will reduce or el

June 18, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14AINFORMATION Proxy Statement Pursuant To Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14AINFORMATION Proxy Statement Pursuant To Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for use of the Commission Only (as permitted by Rul

June 6, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14AINFORMATION Proxy Statement Pursuant To Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14AINFORMATION Proxy Statement Pursuant To Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for use of the Commission Only (as permitted by Rul

May 15, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 OR ☐ TRANSITION REPOR

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from       to Commission file num

May 12, 2025 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 1

May 1, 2025 POS AM

As filed with the Securities and Exchange Commission on May 1, 2025

As filed with the Securities and Exchange Commission on May 1, 2025 Registration No.

May 1, 2025 S-8 POS

As filed with the Securities and Exchange Commission on May 1, 2025

As filed with the Securities and Exchange Commission on May 1, 2025 Registration No.

May 1, 2025 S-8 POS

As filed with the Securities and Exchange Commission on May 1, 2025

As filed with the Securities and Exchange Commission on May 1, 2025 Registration No.

May 1, 2025 S-8 POS

As filed with the Securities and Exchange Commission on May 1, 2025

As filed with the Securities and Exchange Commission on May 1, 2025 Registration No.

May 1, 2025 POS AM

As filed with the Securities and Exchange Commission on May 1, 2025

As filed with the Securities and Exchange Commission on May 1, 2025 Registration No.

May 1, 2025 S-8 POS

As filed with the Securities and Exchange Commission on May 1, 2025

S-8 POS As filed with the Securities and Exchange Commission on May 1, 2025 Registration No.

May 1, 2025 POS AM

As filed with the Securities and Exchange Commission on May 1, 2025

As filed with the Securities and Exchange Commission on May 1, 2025 Registration No.

May 1, 2025 S-8 POS

As filed with the Securities and Exchange Commission on May 1, 2025

As filed with the Securities and Exchange Commission on May 1, 2025 Registration No.

April 30, 2025 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 1

April 28, 2025 25

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 25 NOTIFICATION OF REMOVAL FROM LISTING AND/OR REGISTRATION UNDER SECTION 12(b) OF THE SECURITIES EXCHANGE ACT OF 1934. Commission File Number 001-39244 Vincerx Pharma, Inc.

25 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 25 NOTIFICATION OF REMOVAL FROM LISTING AND/OR REGISTRATION UNDER SECTION 12(b) OF THE SECURITIES EXCHANGE ACT OF 1934. Commission File Number 001-39244 Vincerx Pharma, Inc. The Nasdaq Stock Market LLC (Exact name of Issuer as specified in its charter, and name of Exchange where security is listed and/or registered) 18

April 17, 2025 EX-99.1

Vincerx Pharma, Inc. Announces Intent to Delist from Nasdaq and Deregister with the SEC Vincerx common stock suspended by Nasdaq inadvertently; will resume trading at the open of business on April 21, 2025 Trading to be permanently suspended by Nasda

Exhibit 99.1 Vincerx Pharma, Inc. Announces Intent to Delist from Nasdaq and Deregister with the SEC Vincerx common stock suspended by Nasdaq inadvertently; will resume trading at the open of business on April 21, 2025 Trading to be permanently suspended by Nasdaq at the open of business on April 23, 2025 San Mateo, California, April 17, 2025 – Vincerx Pharma, Inc. (Nasdaq: VINC) today announced i

April 17, 2025 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 14, 2025 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fil

April 17, 2025 EX-2.1

Plan of Liquidation and Dissolution of Vincerx Pharma, Inc.

Exhibit 2.1 PLAN OF LIQUIDATION AND DISSOLUTION OF VINCERX PHARMA, INC. The following Plan of Liquidation and Dissolution (the “Plan of Liquidation”), dated as of April 17, 2025, shall effect the dissolution and complete liquidation of Vincerx Pharma, Inc., a Delaware corporation (the “Company”), in accordance with Section 275 and other applicable provisions of the Delaware General Corporation Law

April 11, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 7, 2025 Vincerx Pharma, Inc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 7, 2025 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission File

April 3, 2025 424B3

$100,000,000 Vincerx Pharma, Inc. Debt Securities Common Stock Preferred Stock Depositary Shares

Table of Contents Filed pursuant to Rule 424(b)(3) Registration No. 333-284478 PROSPECTUS $100,000,000 Vincerx Pharma, Inc. Debt Securities Common Stock Preferred Stock Depositary Shares Warrants Rights We may, from time to time, offer and sell the securities identified above in one or more offerings. The aggregate initial offering price of all securities sold under this prospectus will not exceed

April 3, 2025 424B5

Vincerx Pharma, Inc. Up to $2,707,062 Common Stock

Table of Contents Filed pursuant to Rule 424(b)(5) File No. 333-284478 PROSPECTUS SUPPLEMENT (To prospectus dated April 2, 2025) Vincerx Pharma, Inc. Up to $2,707,062 Common Stock We have entered into a sales agreement, dated January 21, 2025 (the “Sales Agreement”), with H.C. Wainwright & Co., LLC (“Wainwright”) relating to our common stock, $0.0001 par value per share (“Common Stock”), offered b

March 31, 2025 S-3/A

As filed with the Securities and Exchange Commission on March 31, 2025

As filed with the Securities and Exchange Commission on March 31, 2025 Registration No.

March 31, 2025 CORRESP

VINCERX PHARMA, INC. 1825 S. Grant Street San Mateo, California 94402 March 31, 2025

VINCERX PHARMA, INC. 1825 S. Grant Street San Mateo, California 94402 March 31, 2025 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Attention: Alan Campbell    Laura Crotty    Re: Vincerx Pharma, Inc. - Registration Statement – Form S-3 File No. 333-284478 Request for Acceleration of Effectiveness Ladies and Gentlemen: Pu

March 27, 2025 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 OR ☐ TRANSITION REPORT PUR

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from       to       Commission file nu

March 27, 2025 EX-19.1

Insider Trading Policy.

Exhibit 19.1 VINCERX PHARMA, INC. INSIDER TRADING POLICY Policy as to Trades in the Company’s Securities by Company Personnel and Treatment of Confidential Information 1. Purpose. Both the Securities and Exchange Commission (the “SEC”) and Congress are very concerned about maintaining the fairness and integrity of the U.S. capital markets. The securities laws are continually reviewed and amended t

March 27, 2025 EX-3.1

Second Amended and Restated Certificate of Incorporation, as amended through January 27, 2025.

Exhibit 3.1 SECOND AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF LIFESCI ACQUISITION CORP. December 23, 2020 LifeSci Acquisition Corp., a corporation organized and existing under the laws of the State of Delaware, DOES HEREBY CERTIFY AS FOLLOWS: 1. The name of the Corporation is “LifeSci Acquisition Corp.”. The original certificate of incorporation of the corporation was filed with the Secr

March 18, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 14, 2025 Vincerx Pharma, In

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 14, 2025 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fil

March 18, 2025 EX-99.1

Vincerx Pharma Announces Non-Binding Letter of Intent for Business Combination with QumulusAI

EX-99.1 Exhibit 99.1 Vincerx Pharma Announces Non-Binding Letter of Intent for Business Combination with QumulusAI San Mateo, Calif. – Mar. 18, 2025 (GLOBE NEWSWIRE) – Vincerx Pharma, Inc. (Nasdaq: VINC) today announced that it has entered into a non-binding letter of intent (“LOI”) with Global Digital Holdings Inc., conducting business as QumulusAI, a privately-held, high-performance computing in

March 18, 2025 425

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 14, 2025 Vincerx Pharma, In

425 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 14, 2025 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission

March 18, 2025 EX-10.1

Non-Binding Letter of Intent dated March 14, 2025

EX-10.1 Exhibit 10.1 CONFIDENTIAL Project Falcon Non-Binding Letter of Intent This letter of intent (this “LOI”) sets forth our current proposal with regard to a business combination and associated investment between Vincerx Pharma, Inc. (“Vincerx”) and Global Digital Holdings Inc. (“QumulusAI”) (the “Transaction”). This LOI is an expression of intent only, does not express the final agreement of

February 28, 2025 EX-99.1

Vincerx Pharma Announces Termination of Reverse Merger Term Sheet and Evaluation of Strategic Alternatives

EX-99.1 Exhibit 99.1 Vincerx Pharma Announces Termination of Reverse Merger Term Sheet and Evaluation of Strategic Alternatives San Mateo, Calif., Feb. 28, 2025 – Vincerx Pharma, Inc. (Nasdaq: VINC) today announced that the previously signed binding Term Sheet between Vincerx, Oqory, Inc., and Vivasor, Inc. for a reverse merger transaction has been terminated. As a result, the board of directors w

February 28, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 25, 2025 Vincerx Pharma,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 25, 2025 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission

February 18, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 11, 2025 Vincerx Pharma,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 11, 2025 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission

February 7, 2025 CORRESP

* * * * *

Pillsbury Winthrop Shaw Pittman LLP 2550 Hanover Street | Palo Alto, CA 94304-1114 | tel 650.

February 6, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 31, 2025 Vincerx Pharma,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 31, 2025 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission F

February 6, 2025 EX-10.1

Amendment #2 to Binding Term Sheet effective as of January 31, 2025

EX-10.1 Exhibit 10.1 AMENDMENT #2 TO BINDING TERM SHEET FOR BUSINESS COMBINATION BETWEEN VINCERX PHARMA, INC. AND OQORY, INC. This AMENDMENT #2 TO BINDING TERM SHEET (this “Amendment”), effective as of January 31, 2025 (the “Amendment Effective Date”), is by and among Vincerx Pharma, Inc., a Delaware corporation (“Vincerx”), Oqory, Inc., a Delaware corporation (“Oqory”), a Delaware corporation (th

February 6, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 31, 2025 Vincerx Pharma,

DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 31, 2025 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Comm

January 29, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

January 24, 2025 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Tables S-3 (Form Type) Vincerx Pharma, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1:Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered(1) Proposed Maximum  Offering  Price Per  Unit  Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee(2

January 24, 2025 EX-4.1

Form of Indenture relating to debt securities.

Exhibit 4.1 VINCERX PHARMA, INC. TO [   ] Trustee Indenture Dated as of    , 20 VINCERX PHARMA, INC. Reconciliation and tie between Trust Indenture Act of 1939 and Indenture, dated as of     , 20 Trust Indenture Act Section Indenture Sections § 310(a)(1) 609 (a)(2) 609 (a)(3) Not Applicable (a)(4) Not Applicable (a)(5) 609 (b) 608 610 § 311(a) 613(a) (b) 613(b) (b)(2) 703(a)(2) 703(b) § 312(a) 701

January 24, 2025 S-3

As filed with the Securities and Exchange Commission on January 24, 2025

Table of Contents As filed with the Securities and Exchange Commission on January 24, 2025 Registration No.

January 23, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 23, 2025 Vincerx Pharma,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 23, 2025 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission F

January 23, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 23, 2025 Vincerx Pharma,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 23, 2025 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission F

January 23, 2025 EX-99.1

FORWARD-LOOKING STATEMENTS AND TRADEMARKS FORWARD-LOOKING STATEMENTS No representations or warranties, expressed or implied are given in, or in respect of, this presentation. To the fullest extent permitted by law, in no circumstances will Oqory or V

Exhibit 99.1 ee Investor Presentation Li nvestor J January anuary 2 23, 3, 22025 025 PHARMA. FORWARD-LOOKING STATEMENTS AND TRADEMARKS FORWARD-LOOKING STATEMENTS No representations or warranties, expressed or implied are given in, or in respect of, this presentation. To the fullest extent permitted by law, in no circumstances will Oqory or Vincerx, or any of their respective subsidiaries, stockhol

January 23, 2025 8-K

Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 23, 2025 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission F

January 23, 2025 EX-99.1

Vincerx Pharma, Inc. Announces Reverse Stock Split Vincerx’s Common Stock to Begin Trading on a Split-adjusted Basis on January 28, 2025

Exhibit 99.1 Vincerx Pharma, Inc. Announces Reverse Stock Split Vincerx’s Common Stock to Begin Trading on a Split-adjusted Basis on January 28, 2025 SAN MATEO, California — January 23, 2025 – Vincerx Pharma, Inc. (Nasdaq: VINC), a biopharmaceutical company aspiring to address the unmet medical needs of patients with cancer through paradigm-shifting therapeutics, today announced that its board of

January 21, 2025 EX-10.1

Sales Agreement dated January 21, 2025 between Vincerx Pharma, Inc. and H.C. Wainwright & Co., LLC.

Exhibit 10.1 VINCERX PHARMA, INC. Shares of Common Stock ($0.0001 par value per share) SALES AGREEMENT January 21, 2025 H.C. Wainwright & Co., LLC 430 Park Avenue New York, New York 10022 Ladies and Gentlemen: Vincerx Pharma, Inc., a Delaware corporation (the “Company”), confirms its agreement (this “Agreement”) with H.C. Wainwright & Co., LLC (the “Agent”), as follows: 1. Issuance and Sale of Sha

January 21, 2025 EX-99.1

2

Exhibit 99.1 We have entered into a binding term sheet with Oqory, Inc., a Delaware corporation (“Oqory”), and Vivasor, Inc., Oqory’s parent corporation, relating to a proposed business combination between Vincerx and Oqory. Oqory is a private biopharmaceutical company dedicated to developing next-generation antibody-drug conjugates for the treatment of cancer, focused on the development of Oqory’

January 21, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 21, 2025 Vincerx Pharma,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 21, 2025 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission F

January 21, 2025 424B5

Vincerx Pharma, Inc. Up to $30,000,000 Common Stock

424B5 Table of Contents Filed pursuant to Rule 424(b)([5]) File No. 333-262239 PROSPECTUS SUPPLEMENT (To prospectus dated January 28, 2022) Vincerx Pharma, Inc. Up to $30,000,000 Common Stock We have entered into a sales agreement, dated January 21, 2025 (the “Sales Agreement”), with H.C. Wainwright & Co., LLC (“Wainwright”) relating to our common stock, $0.0001 par value per share (“Common Stock”

January 16, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 10, 2025 Vincerx Pharma,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 10, 2025 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission F

December 27, 2024 424B5

Vincerx Pharma, Inc. 2,816,250 Shares of Common Stock Pre-Funded Warrants to Purchase up to 2,635,820 Shares of Common Stock Common Warrants to Purchase up to 10,904,140 Shares of Common Stock Up to 2,635,820 Shares of Common Stock Underlying the Pre

Table of Contents Filed pursuant to Rule 424(b)(5) File No. 333-262239 PROSPECTUS SUPPLEMENT (To prospectus dated January 28, 2022) Vincerx Pharma, Inc. 2,816,250 Shares of Common Stock Pre-Funded Warrants to Purchase up to 2,635,820 Shares of Common Stock Common Warrants to Purchase up to 10,904,140 Shares of Common Stock Up to 2,635,820 Shares of Common Stock Underlying the Pre-Funded Warrants U

December 27, 2024 EX-4.2

Form of Common Stock Warrant

Exhibit 4.2 COMMON STOCK PURCHASE WARRANT VINCERX PHARMA, INC. Warrant Shares:   Issue Date: , 2024           THIS COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the Stockholder Approval Date (the “

December 27, 2024 EX-99.1

Vincerx Pharma Enters into a Binding Term Sheet for a Strategic Merger with Oqory, Inc. Proposed merger would add a differentiated Phase 3 TROP2 Antibody-drug Conjugate (ADC) to the combined company’s pipeline

EX-99.1 Exhibit 99.1 Vincerx Pharma Enters into a Binding Term Sheet for a Strategic Merger with Oqory, Inc. Proposed merger would add a differentiated Phase 3 TROP2 Antibody-drug Conjugate (ADC) to the combined company’s pipeline PALO ALTO, California, December 27, 2024 — Vincerx Pharma, Inc. (Nasdaq: VINC), a biopharmaceutical company aspiring to address the unmet medical needs of patients with

December 27, 2024 EX-4.1

Form of Pre-Funded Warrant

Exhibit 4.1 PRE-FUNDED COMMON STOCK PURCHASE WARRANT VINCERX PHARMA, INC. Warrant Shares: Issue Date: , 2024 Initial Exercise Date: , 2024 THIS PRE-FUNDED COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or af

December 27, 2024 EX-10.1

Binding Term Sheet, as amended

EX-10.1 Exhibit 10.1 AMENDMENT #1 TO BINDING TERM SHEET FOR BUSINESS COMBINATION BETWEEN VINCERX PHARMA, INC. AND OQORY, INC. This AMENDMENT #1 TO BINDING TERM SHEET (this “Amendment”), effective as of December 26, 2024 (the “Amendment Effective Date”), is by and among Vincerx Pharma, Inc., a Delaware corporation (“Vincerx”), Oqory, Inc., a Delaware corporation (“Oqory”), a Delaware corporation (t

December 27, 2024 EX-10.2

Securities Purchase Agreement

Exhibit 10.2 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of December 26, 2024, between Vincerx Pharma, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”). WHEREAS, subject to the terms and conditions

December 27, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 20, 2024 Vincerx Pharma,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 20, 2024 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission

December 27, 2024 EX-99.2

Risks Related to the Proposed Business Combination

Exhibit 99.2 Risks Related to the Proposed Business Combination The announced transactions with Oqory and its affiliates may not be consummated on the terms described in the binding term sheet or at all. We have entered into a binding term sheet (the “Term Sheet”) with Oqory, Inc., a Delaware corporation (“Oqory”), and Vivasor, Inc., Oqory’s parent corporation, relating to a proposed business comb

December 10, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  )

DEF 14A Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

December 6, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 2, 2024 Vincerx Pharma,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 2, 2024 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission F

December 6, 2024 EX-99.1

Vincerx Pharma to Implement Cost-Controls to Support Advancing Phase 1 Study of VIP943

Exhibit 99.1 Vincerx Pharma to Implement Cost-Controls to Support Advancing Phase 1 Study of VIP943 December 4, 2024 Also Exploring Strategic Alternatives to Complement Fundraising Efforts PALO ALTO, Calif., Dec. 04, 2024 (GLOBE NEWSWIRE) — Vincerx Pharma, Inc. (Nasdaq: VINC), a biopharmaceutical company aspiring to address the unmet medical needs of patients with cancer through paradigm-shifting

November 25, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 25, 2024 Vincerx Pharma,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 25, 2024 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission

November 14, 2024 SC 13G

VINC / Vincerx Pharma, Inc. / ARMISTICE CAPITAL, LLC Passive Investment

SC 13G 1 armistice-vinc093024.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Vincerx Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value per share (Title of Class of Securities) 92731L106 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of this Statement) Check the ap

November 14, 2024 EX-99

LIMITED POWER OF ATTORNEY BANK OF AMERICA CORPORATION

EX-99 2 bacpoa.htm BANK OF AMERICA CORPORATION LIMITED POWER OF ATTORNEY BANK OF AMERICA CORPORATION, a Delaware corporation (the "Corporation" ), does hereby make, constitute, and appoint each of Marie Andre, Andres Ortiz Custodio, Kamil Dziedzic, Valerie Ezeagbo, Kelvin Kwo k, Frank Lui, James Todd, Ben Tsoi, Michelle Wong, and Monica Yako as an attorney-in-fact for the Corporation acting for th

November 14, 2024 SC 13G/A

VINC / Vincerx Pharma, Inc. / BANK OF AMERICA CORP /DE/ Passive Investment

SC 13G/A 1 doc1.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 01)* Vincerx Pharma, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 92731L106 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule p

November 13, 2024 SC 13G/A

VINC / Vincerx Pharma, Inc. / Prosight Management, LP - SC 13G/A Passive Investment

SC 13G/A 1 d892826dsc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* VINCERX PHARMA, INC. (Name of Issuer) Common Stock, $0.0001 par value per share (Title of Class of Securities) 92731L106 (CUSIP Number) September 30, 2024 (Date of Event which Requires Filing of this Statement) Chec

November 12, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 12, 2024 Vincerx Pharma,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 12, 2024 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission

November 12, 2024 EX-99.1

Vincerx Pharma Reports Third Quarter 2024 Financial Results Continued enrollment and dose escalation in Phase 1 study of VIP943, a potentially best-in-class anti-CD123 antibody-drug conjugate (ADC); additional data expected by early 2025 Completed Ph

Exhibit 99.1 Vincerx Pharma Reports Third Quarter 2024 Financial Results Continued enrollment and dose escalation in Phase 1 study of VIP943, a potentially best-in-class anti-CD123 antibody-drug conjugate (ADC); additional data expected by early 2025 Completed Phase 1 dose-escalation studies of small molecule drug-conjugate (SMDC), VIP236, and CDK9 inhibitor, enitociclib, and identified the maximu

November 12, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 OR ☐ TRANSITION R

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from      to      Commission

November 5, 2024 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  )

PRE 14A Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

October 7, 2024 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 7, 2024 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fi

September 30, 2024 SC TO-I/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO/A (Amendment No. 3) Tender Offer Statement Under Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 Vincerx Pharma, Inc. (Name of Subject Company (Is

SC TO-I/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO/A (Amendment No. 3) Tender Offer Statement Under Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 Vincerx Pharma, Inc. (Name of Subject Company (Issuer) and Filing Person (Offeror)) Options to Purchase Common Stock, Par Value $0.0001 Per Share (Title of Class of Securities) 92731L106 (C

September 10, 2024 SC TO-I/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO/A (Amendment No. 2) Tender Offer Statement Under Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 Vincerx Pharma, Inc. (Name of Subject Company (Is

SC TO-I/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO/A (Amendment No. 2) Tender Offer Statement Under Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 Vincerx Pharma, Inc. (Name of Subject Company (Issuer) and Filing Person (Offeror)) Options to Purchase Common Stock, Par Value $0.0001 Per Share (Title of Class of Securities) 92731L106 (C

September 10, 2024 EX-99.(A)(1)(L)

Form of Email Announcement Regarding Extension of the Exchange Offer

Exhibit (a)(1)(L) To: Eligible Holders CC: Gabriela Jairala Subject: Update: Extension of Period to Exchange Eligible Options for New Restricted Stock Units (RSUs) Hello everyone, Please be aware that Vincerx’s Compensation Committee has extended the expiration time of the Exchange Offer to 5:00 p.

August 19, 2024 SC TO-I/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO/A (Amendment No. 1) Tender Offer Statement Under Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 Vincerx Pharma, Inc. (Name of Subject Company (Is

SC TO-I/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO/A (Amendment No. 1) Tender Offer Statement Under Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 Vincerx Pharma, Inc. (Name of Subject Company (Issuer) and Filing Person (Offeror)) Options to Purchase Common Stock, Par Value $0.0001 Per Share (Title of Class of Securities) 92731L106 (C

August 19, 2024 EX-99.(A)(1)(K)

Stock Option Repricing and Exchange Program Presentation

Exhibit (a)(1)(K) Vincerx Stock Option Repricing and Exchange Program 19 August 2024 CONFIDENTIAL Purpose of Stock Option Repricing and Exchange Program Prior to the repricing, all Vincerx stock options were “underwater” (i.

August 16, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 12, 2024 Vincerx Pharma, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 12, 2024 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fi

August 13, 2024 EX-99.(A)(1)(H)

Form of Confirmation Letter to Eligible Holders Participating in the Exchange Confirming Acceptance of Eligible Options

Exhibit (a)(1)(H) FORM OF CONFIRMATION LETTER TO ELIGIBLE HOLDERS PARTICIPATING IN THE EXCHANGE CONFIRMING ACCEPTANCE OF ELIGIBLE OPTIONS Date: [], 2024 To: [] From: Vincerx Pharma, Inc.

August 13, 2024 EX-99.(A)(1)(G)

Form of Reminder Email to Eligible Holders

Exhibit (a)(1)(G) Subject: REMINDER – Vincerx Pharma, Inc. Offer to Exchange Eligible Options for New Restricted Stock Units To: Eligible Holders Date: [], 2024 This email is intended to serve as a reminder that we are nearing the expiration of the Exchange Offer described in the Offer to Exchange Eligible Options for New Restricted Stock Units dated August 13, 2024 (the “Exchange Offer”). The Exc

August 13, 2024 EX-99.(A)(1)(J)

Form of Repricing Notice

Exhibit (a)(1)(J) [NAME] [ADDRESS] [DATE] Re: Repricing of Stock Options Dear : I am pleased to announce that the Board of Directors of Vincerx Pharma, Inc.

August 13, 2024 EX-99.(A)(1)(F)

Form of Communication to Eligible Holders Confirming Receipt of Notice of Withdrawal of Election Form

Exhibit (a)(1)(F) FORM OF COMMUNICATION TO ELIGIBLE HOLDERS CONFIRMING RECEIPT OF NOTICE OF WITHDRAWAL OF ELECTION FORM Date: [], 2024 To: [] From: Vincerx Pharma, Inc.

August 13, 2024 EX-99.(A)(1)(I)

Form of New RSU Grant Notice and Agreement

Exhibit (a)(1)(I) Replacement RSU VINCERX PHARMA, INC. 2020 STOCK INCENTIVE PLAN NOTICE OF RESTRICTED STOCK UNIT AWARD You are receiving the following Restricted Stock Units (the “Restricted Stock Units,” “RSUs” or this “Award”) pursuant to your election to participate in the Offer to Exchange Eligible Options for New Restricted Stock Units dated August 13, 2024, under which you surrendered option

August 13, 2024 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Table Schedule TO-I (Form Type) Vincerx Pharma, Inc.

August 13, 2024 EX-99.(A)(1)(E)

Form of Communication to Eligible Holders Participating in the Exchange Offer Confirming Receipt of Election Form

Exhibit (a)(1)(E) FORM OF COMMUNICATION TO ELIGIBLE HOLDERS PARTICIPATING IN THE EXCHANGE OFFER CONFIRMING RECEIPT OF ELECTION FORM Date: [], 2024 To: [] From: Vincerx Pharma, Inc.

August 13, 2024 EX-99.(A)(1)(D)

Notice of Withdrawal of Election Form

Exhibit (a)(1)(D) VINCERX PHARMA, INC. NOTICE OF WITHDRAWAL OF ELECTION FORM INSTRUCTIONS If you previously elected to accept the offer by Vincerx Pharma, Inc. (“Vincerx”) to exchange some or all of your outstanding Eligible Options for New RSUs, subject to the terms and conditions set forth in the Offer to Exchange Eligible Options for New Restricted Stock Units dated August 13, 2024 (the “Exchan

August 13, 2024 EX-99.(A)(1)(B)

Form of Email Announcement of Offer to Exchange

Exhibit (a)(1)(B) Subject: Vincerx Pharma, Inc. Offer to Exchange Eligible Options for New Restricted Stock Units To: Eligible Holders Date: August 13, 2024 We are pleased to announce that Vincerx Pharma, Inc. (“Vincerx”) is commencing an Offer to Exchange Eligible Options for New Restricted Stock Units (referred to as the “Exchange Offer”) today, Tuesday, August 13, 2024. The Exchange Offer progr

August 13, 2024 SC TO-I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO Tender Offer Statement Under Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 Vincerx Pharma, Inc. (Name of Subject Company (Issuer) and Filing Per

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO Tender Offer Statement Under Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 Vincerx Pharma, Inc. (Name of Subject Company (Issuer) and Filing Person (Offeror)) Options to Purchase Common Stock, Par Value $0.0001 Per Share (Title of Class of Securities) 92731L106 (CUSIP Number of Common Stock Un

August 13, 2024 EX-99.(A)(1)(C)

Election Form

Exhibit (a)(1)(C) ELECTION FORM Before signing this Election Form, please make sure you have received, read and understand the documents that make up this offer, including (1) the Offer to Exchange Eligible Options for New Restricted Stock Units dated August 13, 2024 filed with the U.

August 13, 2024 EX-99.(A)(1)(A)

Offer to Exchange Eligible Options for New Restricted Stock Units, dated August 13, 2024

Exhibit (a)(1)(A) VINCERX PHARMA, INC. 260 SHERIDAN AVENUE, SUITE 400 PALO ALTO, CALIFORNIA 94306 OFFER TO EXCHANGE ELIGIBLE OPTIONS FOR NEW RESTRICTED STOCK UNITS VINCERX PHARMA, INC. SUMMARY TERM SHEET — OVERVIEW OFFER TO EXCHANGE ELIGIBLE OPTIONS FOR NEW RESTRICTED STOCK UNITS This offer and withdrawal rights will expire at 5:00 p.m., U.S. Pacific Time, on Wednesday, September 11, 2024, unless

August 8, 2024 EX-99.1

Vincerx Pharma Reports Second Quarter 2024 Financial Results Vincerx continues to enroll its Phase 1 studies of antibody-drug conjugate (ADC) VIP943, with data expected by the end of Q4 2024, and small molecule drug-conjugate (SMDC) VIP236, with data

Exhibit 99.1 Vincerx Pharma Reports Second Quarter 2024 Financial Results Vincerx continues to enroll its Phase 1 studies of antibody-drug conjugate (ADC) VIP943, with data expected by the end of Q4 2024, and small molecule drug-conjugate (SMDC) VIP236, with data expected at the end of Q3 2024 Expected cash runway through 2024 PALO ALTO, Calif., August 8, 2024 – Vincerx Pharma, Inc. (Nasdaq: VINC)

August 8, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 OR ☐ TRANSITION REPORT

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from      to      Commission file

August 8, 2024 8-K

Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 8, 2024 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fil

August 2, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  ) Filed by the Registrant ☒ Filed by a party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e

July 8, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  ) Filed by the Registrant  ☒ Filed by a Party other than the Registrant  ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule

June 28, 2024 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  )

PRE 14A Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

June 21, 2024 S-8

As filed with the Securities and Exchange Commission on June 21, 2024

S-8 As filed with the Securities and Exchange Commission on June 21, 2024 Registration No.

June 21, 2024 EX-99.1

Vincerx Pharma, Inc. 2020 Stock Incentive Plan, as amended (incorporated by reference to Exhibit 99.1 to the Registration Statement on Form S-8 (File No. 333-280382) filed on June 21, 2024).

Exhibit 99.1 VINCERX PHARMA, INC. 2020 STOCK INCENTIVE PLAN (As amended on March 7, 2024) TABLE OF CONTENTS Page SECTION 1. ESTABLISHMENT AND PURPOSE 1 SECTION 2. DEFINITIONS 1 (a) “Affiliate” 1 (b) “Award” 1 (c) “Award Agreement” 1 (d) “Board of Directors” or “Board” 1 (e) “Cash-Based Award” 1 (f) “Change in Control” 1 (g) “Code” 3 (h) “Committee” 3 (i) “Company” 3 (j) “Consultant” 3 (k) “Disabil

June 21, 2024 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Vincerx Pharma, Inc.

May 28, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 22, 2024 Vincerx Pharma, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 22, 2024 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission File

May 28, 2024 EX-3.1

Amended and Restated Bylaws, as amended as of May 23, 2024

EX-3.1 Exhibit 3.1 AMENDED AND RESTATED BYLAWS OF VINCERX PHARMA, INC. (formerly known as Vincera Pharma, Inc.) (a Delaware corporation) (As amended as of May 23, 2024) TABLE OF CONTENTS Page ARTICLE 1 Offices 1 1.1 Registered Office 1 1.2 Other Offices 1 ARTICLE 2 Meeting of Stockholders 1 2.1 Place of Meeting 1 2.2 Annual Meeting 1 2.3 Special Meetings 3 2.4 Notice of Meetings 3 2.5 List of Stoc

May 14, 2024 EX-99.1

Vincerx Pharma Reports First Quarter 2024 Financial Results and Provides Corporate Update Vincerx continued to progress Phase 1 dose-escalation studies for VIP943, a potentially best-in-class anti- CD123 antibody-drug conjugate (ADC), and VIP236, a f

Exhibit 99.1 Vincerx Pharma Reports First Quarter 2024 Financial Results and Provides Corporate Update Vincerx continued to progress Phase 1 dose-escalation studies for VIP943, a potentially best-in-class anti- CD123 antibody-drug conjugate (ADC), and VIP236, a first-in-class small molecule-drug conjugate (SMDC) The National Institutes of Health (NIH) and Vincerx announced positive results from en

May 14, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 14, 2024 Vincerx Pharma, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 14, 2024 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission File

May 14, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 OR ☐ TRANSITION REPOR

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from         to         Commissio

May 3, 2024 SC 13G

VINC / Vincerx Pharma, Inc. / Prosight Management, LP - SC 13G Passive Investment

SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* VINCERX PHARMA, INC. (Name of Issuer) Common Stock, $0.0001 par value per share (Title of Class of Securities) 92731L106 (CUSIP Number) April 25, 2024 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate th

May 3, 2024 EX-99.1

JOINT FILING AGREEMENT May 3, 2024

EX-99.1 Exhibit 99.1 JOINT FILING AGREEMENT May 3, 2024 Pursuant to and in accordance with the Securities Exchange Act of 1934, as amended (the “Act”), and the rules and regulations thereunder, each party hereto hereby agrees to the joint filing, on behalf of each of them, of any filing required by such party under Section 13 or Section 16 of the Act or any rule or regulation thereunder (including

April 29, 2024 424B5

Vincerx Pharma, Inc. 6,000,000 Shares of Common Stock Pre-Funded Warrants to Purchase up to 16,000,000 Shares of Common Stock Warrants to Purchase up to 22,000,000 Shares of Common Stock

Table of Contents Filed pursuant to Rule 424(b)(5) File No. 333-262239 PROSPECTUS SUPPLEMENT (To prospectus dated January 28, 2022) Vincerx Pharma, Inc. 6,000,000 Shares of Common Stock Pre-Funded Warrants to Purchase up to 16,000,000 Shares of Common Stock Warrants to Purchase up to 22,000,000 Shares of Common Stock We are offering 6,000,000 shares of our common stock, $0.0001 par value per share

April 26, 2024 EX-4.2

Form of Common Stock Warrant (incorporated by reference to Exhibit 4.2 to the Current Report on Form 8-K filed on April 26, 2024).

Exhibit 4.2 WARRANT TO PURCHASE COMMON STOCK VINCERX PHARMA, INC. Number of Warrant Shares: Issue Date: [ ], 2024 THIS WARRANT TO PURCHASE COMMON STOCK (the “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the Issue Date and on or prio

April 26, 2024 EX-4.1

Form of Pre-Funded Warrant (incorporated by reference to Exhibit 4.1 to the Current Report on Form 8-K filed on April 26, 2024).

Exhibit 4.1 VINCERX PHARMA, INC. FORM OF PRE-FUNDED WARRANT TO PURCHASE COMMON STOCK Number of Shares: [ ] (subject to adjustment) Warrant No. Original Issue Date: [ ], 2024 Vincerx Pharma, Inc., a Delaware corporation (the “Company”), hereby certifies that, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, [ ] or its registered assigns (the “Holder

April 26, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 25, 2024 Vincerx Pharma, In

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 25, 2024 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fil

April 26, 2024 EX-1.1

Underwriting Agreement dated as of April 25, 2024 by and between Vincerx Pharma, Inc. and Leerink Partners LLC.

Exhibit 1.1 Execution Version VINCERX PHARMA, INC. (a Delaware corporation) 6,000,000 Shares of Common Stock Pre-Funded Warrants to Purchase 16,000,000 Shares of Common Stock Warrants to Purchase 22,000,000 Shares of Common Stock UNDERWRITING AGREEMENT April 25, 2024 Leerink Partners LLC as Representative of the several Underwriters c/o Leerink Partners LLC 1301 Avenue of the Americas, 12th Floor

April 26, 2024 EX-99.1

Vincerx Pharma Announces Pricing of Underwritten Public Offering of Common Stock and Warrants

Exhibit 99.1 Vincerx Pharma Announces Pricing of Underwritten Public Offering of Common Stock and Warrants PALO ALTO, California, April 25, 2024 — Vincerx Pharma, Inc. (Nasdaq: VINC) today announced the pricing of an underwritten public offering of (i) 6,000,000 shares of its common stock and accompanying common stock warrants to purchase an aggregate of 6,000,000 shares of common stock, and (ii)

April 25, 2024 EX-99.1

Vincerx Pharma Announces Proposed Underwritten Public Offering of Common Stock and Warrants

Exhibit 99.1 Vincerx Pharma Announces Proposed Underwritten Public Offering of Common Stock and Warrants PALO ALTO, CA, April 25, 2024 — Vincerx Pharma, Inc. (Nasdaq: VINC) today announced a proposed underwritten public offering of shares of its common stock and accompanying common stock warrants to purchase shares of its common stock and, to certain investors, pre-funded warrants to purchase shar

April 25, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 25, 2024 Vincerx Pharma, In

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 25, 2024 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fil

April 25, 2024 424B5

SUBJECT TO COMPLETION, DATED APRIL 25, 2024

424B5 Table of Contents Filed pursuant to Rule 424(b)(5) File No. 333-262239 The information in this prospectus supplement is not complete and may be changed. A registration statement relating to these securities has been declared effective by the Securities and Exchange Commission. This preliminary prospectus supplement and the accompanying prospectus are not an offer to sell these securities, an

April 10, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEF 14A Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

April 10, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  )

DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)

April 8, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 8, 2024 Vincerx Pharma, Inc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 8, 2024 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission File

March 29, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 29, 2024 Vincerx Pharma, In

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 29, 2024 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fil

March 29, 2024 EX-97.1

Policy Relating to Recovery of Erroneously Awarded Compensation.

Exhibit 97.1 VINCERX PHARMA, INC. INCENTIVE-BASED COMPENSATION RECOUPMENT POLICY 1. Purpose The Board of Directors (the “Board”) of Vincerx Pharma, Inc., a Delaware corporation (the “Company”), has adopted this Incentive-Based Compensation Recoupment Policy (this “Policy”) to comply with Section 954 of the Dodd-Frank Wall Street Reform and Consumer Protection Act of 2010, as codified by Section 10

March 29, 2024 424B5

Vincerx Pharma, Inc. Up to $50,000,000 Common Stock

424B5 Table of Contents Filed pursuant to Rule 424(b)(5) Registration no. 333-262239 PROSPECTUS SUPPLEMENT (To prospectus dated January 28, 2022) Vincerx Pharma, Inc. Up to $50,000,000 Common Stock We have entered into a sales agreement, dated March 29, 2024 (the “Sales Agreement”), with Leerink Partners LLC (“Leerink Partners”), relating to our common stock, $0.0001 par value per share (“Common S

March 29, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 29, 2024 Vincerx Pharma, In

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 29, 2024 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fil

March 29, 2024 EX-21.1

Subsidiaries of the Company.

Exhibit 21.1 Subsidiaries of Vincerx Pharma, Inc. Subsidiary Jurisdiction VNRX Corp. Delaware Vincerx Pharma GmbH Germany Vincerx Pharma Australia Pty. Australia

March 29, 2024 EX-99.1

Vincerx Pharma Reports Fourth Quarter and Full Year 2023 Financial Results and Corporate Update VIP236, first-in-class small molecule-drug conjugate (SMDC), preliminary Phase 1 data and update on pipeline progress will be presented by management at a

Exhibit 99.1 Vincerx Pharma Reports Fourth Quarter and Full Year 2023 Financial Results and Corporate Update VIP236, first-in-class small molecule-drug conjugate (SMDC), preliminary Phase 1 data and update on pipeline progress will be presented by management at a virtual investor event on April 8 at 2:00 PM PT Phase 1 trial ongoing for VIP943, a best-in-class anti-CD123 antibody-drug conjugate (AD

March 29, 2024 EX-10.1

Sales Agreement by and between Vincerx Pharma, Inc. and Leerink Partners LLC, dated March 29, 2024 (incorporated by reference to Exhibit 10.1 to the Current Report on Form 8-K filed on March 29, 2024).

Exhibit 10.1 VINCERX PHARMA, INC. Shares of Common Stock ($0.0001 par value per share) SALES AGREEMENT March 29, 2024 LEERINK PARTNERS LLC 1301 Avenue of the Americas, 12th Floor New York, New York 10019 Ladies and Gentlemen: Vincerx Pharma, Inc., a Delaware corporation (the “Company”), confirms its agreement (this “Agreement”) with Leerink Partners LLC (the “Agent”), as follows: 1. Issuance and S

March 29, 2024 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 OR ☐ TRANSITION REPORT PUR

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from          to          Commission f

February 14, 2024 EX-1

JOINT FILING AGREEMENT

EX-1 2 ex1.htm EXHIBIT 1 Exhibit 1 JOINT FILING AGREEMENT Pursuant to Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, each of the undersigned acknowledges and agrees that the foregoing statement on this Schedule 13G is filed on behalf of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of the undersigned without the

February 14, 2024 SC 13G/A

VINC / Vincerx Pharma, Inc. / Long Focus Capital Management, Llc - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Vincerx Pharma, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 92731L106 (CUSIP Number) Long Focus Capital Management LLC 207 Calle Del Parque A&M Tower, 8th Floor San Juan, PR 00912 (787) 333-0240 (Name, Address and Telephone Number o

February 13, 2024 SC 13G

VINC / Vincerx Pharma, Inc. / BANK OF AMERICA CORP /DE/ Passive Investment

SC 13G 1 doc1.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. N/A)* Vincerx Pharma, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 92731L106 (CUSIP Number) December 31, 2023 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursu

February 13, 2024 EX-99

BANK OF AMERICA CORPORATION LIMITED POWER OF ATTORNEY

EX-99 2 bacpoa.htm BANK OF AMERICA CORPORATION LIMITED POWER OF ATTORNEY BANK OF AMERICA CORPORATION, a Delaware corporation (the "Corporation"), does hereby make, constitute, and appoint each of Szabina Biro, Hannah Chae, Andres Ortiz Custodio, Kamil Dziedzic, Krishnan Harihanran, Kelvin Kwok, Frank Lui, James Todd, Michelle Wong, and Monica Yako as an attorney-in-fact for the Corporation acting

February 13, 2024 SC 13G/A

VINC / Vincerx Pharma, Inc. / Affinity Asset Advisors, LLC - AMENDMENT TO FORM SC 13G Passive Investment

SC 13G/A 1 vincerxsch13ga-021324.htm AMENDMENT TO FORM SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* Vincerx Pharma, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 92731L106 (CUSIP Number) Michael Hirschberg, Esq. Reitler Kailas & Rosenblatt LLP

January 16, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 12, 2024 Vincerx Pharma,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 12, 2024 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission F

November 14, 2023 EX-99.1

Vincerx Pharma Reports Third Quarter 2023 Financial Results and Provides Corporate Update Phase 1 dose escalation for VIP943 - first antibody-drug conjugate (ADC) from VersAptx™, versatile and adaptable, next-generation bioconjugation platform - move

Exhibit 99.1 Vincerx Pharma Reports Third Quarter 2023 Financial Results and Provides Corporate Update Phase 1 dose escalation for VIP943 - first antibody-drug conjugate (ADC) from VersAptx™, versatile and adaptable, next-generation bioconjugation platform - moves quickly into 2nd cohort Phase 1 dose escalation for VIP236 - first-in-class small molecule-drug conjugate (SMDC) for treatment of solid

November 14, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 14, 2023 Vincerx Pharma,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 14, 2023 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission

November 14, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 OR ☐ TRANSITION R

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from       to        Commissi

September 15, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 14, 2023 Vincerx Pharma

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 14, 2023 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission

August 7, 2023 EX-99.1

Vincerx Pharma Reports Second Quarter 2023 Financial Results and Provides Corporate Update IND Application filed for potential best-in-class ADC, VIP943; Phase 1 trial expected to begin Q4 2023 Enrollment continues in Phase 1 dose escalation study fo

EX-99.1 Exhibit 99.1 Vincerx Pharma Reports Second Quarter 2023 Financial Results and Provides Corporate Update IND Application filed for potential best-in-class ADC, VIP943; Phase 1 trial expected to begin Q4 2023 Enrollment continues in Phase 1 dose escalation study for VIP236, a first-in-class SMDC Cash balance expected to support planned operations into late 2024 PALO ALTO, California, August

August 7, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2023 Vincerx Pharma, In

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2023 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fil

August 7, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 OR ☐ TRANSITION REPORT

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001

June 20, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 13, 2023 Vincerx Pharma, Inc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 13, 2023 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission File

May 30, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 25, 2023 Vincerx Pharma, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 25, 2023 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission File

May 11, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 OR ☐ TRANSITION REPOR

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 00

May 11, 2023 EX-99.1

Vincerx Pharma Reports First Quarter 2023 Financial Results and Provides Corporate Update Enrollment continues in Phase 1 dose escalation study for VIP236, a first-in-class αvb3 small molecule drug conjugate (SMDC) for the treatment of solid tumors I

EX-99.1 Exhibit 99.1 Vincerx Pharma Reports First Quarter 2023 Financial Results and Provides Corporate Update Enrollment continues in Phase 1 dose escalation study for VIP236, a first-in-class αvb3 small molecule drug conjugate (SMDC) for the treatment of solid tumors IND filing for VIP943, a next-generation antibody-drug conjugate (ADC), for treatment of CD123+ hematologic malignancies on track

May 11, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 9, 2023 Vincerx Pharma, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 9, 2023 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission File N

April 12, 2023 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEF 14A Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

April 12, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEFA14A 1 d433579ddefa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as

March 28, 2023 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Vincerx Pharma, Inc.

March 28, 2023 EX-99.1

Vincerx Pharma Reports Fourth Quarter and Full Year 2022 Financial Results and Provides a Corporate Update First cohort dosed in Phase 1 first-in-human dose-escalation study of VIP236, an αvß3 small molecule drug conjugate (SMDC) in advanced solid tu

EX-99.1 Exhibit 99.1 Vincerx Pharma Reports Fourth Quarter and Full Year 2022 Financial Results and Provides a Corporate Update First cohort dosed in Phase 1 first-in-human dose-escalation study of VIP236, an αvß3 small molecule drug conjugate (SMDC) in advanced solid tumors IND filing for antibody drug conjugate (ADC) VIP943 remains on track for mid-2023; expected to be in clinic in the second ha

March 28, 2023 10-K

Form 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-392

March 28, 2023 S-8

As filed with the Securities and Exchange Commission on March 28, 2023

S-8 As filed with the Securities and Exchange Commission on March 28, 2023 Registration No.

March 28, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 28, 2023 Vincerx Pharma, In

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 28, 2023 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fil

March 10, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 10, 2023 Vincerx Pharma, In

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 10, 2023 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fil

February 14, 2023 EX-2

IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP

EX-2 3 ex2.htm EXHIBIT 2 Exhibit 2 IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP Long Focus Capital Management, LLC, a Delaware single member limited liability company Long Focus Capital Master, LTD., a Cayman Islands limited company Condagua, LLC, a Delaware single member limited liability company John B. Helmers, a United States citizen A. Glenn Helmers, a United States citizen

February 14, 2023 EX-1

JOINT FILING AGREEMENT

EX-1 2 ex1.htm EXHIBIT 1 Exhibit 1 JOINT FILING AGREEMENT Pursuant to Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, each of the undersigned acknowledges and agrees that the foregoing statement on this Schedule 13G is filed on behalf of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of the undersigned without the

February 14, 2023 SC 13G

VINC / Vincera Pharma, Inc. / Long Focus Capital Management, Llc - SC 13G Passive Investment

SC 13G 1 vincerx13g.htm SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Vincerx Pharma, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 92731L106 (CUSIP Number) Long Focus Capital Management LLC 207 Calle Del Parque A&M Tower, 8th Floor San Juan, PR 00912 (787) 333-0240 (Name,

February 13, 2023 SC 13G/A

VINC / Vincera Pharma, Inc. / Affinity Asset Advisors, LLC - AMENDMENT TO FORM SC 13G Passive Investment

SC 13G/A 1 vinc-sc13ga021323.htm AMENDMENT TO FORM SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Vincerx Pharma, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 92731L106 (CUSIP Number) Michael Hirschberg, Esq. Reitler Kailas & Rosenblatt LLP 885

February 10, 2023 SC 13G/A

VINC / Vincera Pharma, Inc. / Rubric Capital Management LP - SC 13G/A Passive Investment

SC 13G/A 1 tm235947d11sc13ga.htm SC 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1 )* Vincerx Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value per share (Title of Class of Securities) 92731L106 (CUSIP Number) December 31, 2022 (Date of event which requires filing of this statement) Check the app

January 3, 2023 EX-17.2

Letter from Mr. Lowe.

Exhibit 17.2 Ahmed Handy MD Chairman of the Board of Directors and CEO Vincerx Corporation Dear Vincerx team I am writing to tender my resignation from the Board of Directors of Vincerx Corporation (the ?Company?), effective December 31, 2022. My decision to resign from the Company?s board of directors is the result of assessing the company strategy, upon which our views differ. I do not have any

January 3, 2023 EX-17.1

Letter from Dr. McDonald.

Exhibit 17.1 Ahmed Handy MD Chairman of the Board of Directors and CEO Vincerx Corporation Dear Vincerx team I am writing to tender my resignation from the Board of Directors of Vincerx Corporation (the ?Company?), effective December 31, 2022. My decision to resign from the Company?s board of directors is the result of assessing the company strategy, upon which our views differ. I do not have any

January 3, 2023 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 30, 2022 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission

December 29, 2022 SC 13G/A

VINC / Vincera Pharma, Inc. / Flynn James E Passive Investment

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No.

November 10, 2022 EX-99.1

Vincerx Pharma Reports Third Quarter 2022 Financial Results and Provides a Corporate Update Received Orphan Drug Designation for enitociclib; continue to focus on priority indications IND submission for first-in-class small molecule drug conjugate (S

Exhibit 99.1 Vincerx Pharma Reports Third Quarter 2022 Financial Results and Provides a Corporate Update Received Orphan Drug Designation for enitociclib; continue to focus on priority indications IND submission for first-in-class small molecule drug conjugate (SMDC) VIP236 expected by year-end IND filings for antibody drug conjugates (ADCs), VIP943 and VIP924, remain on track for 2H2023 and 1H202

November 10, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 OR ☐ TRANSITION R

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file numbe

November 10, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 10, 2022 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission

November 10, 2022 EX-10.1

Consulting Agreement dated August 19, 2022 with LifeSci Consulting, LLC.

Exhibit 10.1 August 10, 2022 Vincerx Pharma, Inc. 260 Sheridan Avenue, Suite #400 Palo Alto, California 94306 Attn: Ahmed Hamdy, M.D. Dr. Hamdy: This letter (?Agreement?) confirms our understanding that Vincerx Pharma, Inc., (the ?Company?) has engaged LifeSci Consulting, LLC (?LifeSci?), to act as its non-exclusive advisor with respect to the Company?s effort to secure strategic collaboration or

August 31, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 31, 2022 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fi

August 11, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 OR ☐ TRANSITION REPORT

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001

August 11, 2022 EX-99.1

Vincerx Pharma Reports Second Quarter 2022 Financial Results and Provides a Corporate Update Continue to execute on priority indications for VIP152; recently issued the INN enitociclib IND submission for first-in-class small molecule drug conjugate (

Exhibit 99.1 Vincerx Pharma Reports Second Quarter 2022 Financial Results and Provides a Corporate Update Continue to execute on priority indications for VIP152; recently issued the INN enitociclib IND submission for first-in-class small molecule drug conjugate (SMDC) VIP236 still expected in 2H2022 IND filings for antibody drug conjugates (ADCs), VIP943 and VIP924, remain on track for 2H2023 and

August 11, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 11, 2022 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fi

June 7, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Costs Associated with Exit or Disposal Activities, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 4, 2022 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission File

June 7, 2022 EX-99.1

Vincerx Pharma Provides Key Strategic Update Prioritizing Phase 1b VIP152 studies to focus on double-hit DLBCL and CLL Continuing to advance next-generation modular bioconjugation platform; IND filings for VIP236 in 2H22 and for VIP943 in 2H23 remain

Exhibit 99.1 Vincerx Pharma Provides Key Strategic Update Prioritizing Phase 1b VIP152 studies to focus on double-hit DLBCL and CLL Continuing to advance next-generation modular bioconjugation platform; IND filings for VIP236 in 2H22 and for VIP943 in 2H23 remain on track Streamlining and realigning resources to support key indications and programs; extending estimated cash runway into late 2024 P

June 1, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 26, 2022 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission File

May 12, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 12, 2022 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission File

May 12, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022 OR ☐ TRANSITION REPOR

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 00

May 12, 2022 EX-99.1

Vincerx Pharma Reports First Quarter 2022 Financial Results and Provides a Corporate Update Company to present poster on VIP152 at upcoming European Hematology Association Annual Meeting Presented preliminary findings on VIP152 in gynecologic maligna

Exhibit 99.1 Vincerx Pharma Reports First Quarter 2022 Financial Results and Provides a Corporate Update Company to present poster on VIP152 at upcoming European Hematology Association Annual Meeting Presented preliminary findings on VIP152 in gynecologic malignancies in poster at AACR Annual Meeting Continues to execute on Phase 1b VIP152 clinical studies; on track to initiate Phase 2 VIP152 stud

April 12, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEFA14A 1 d328531ddefa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as

April 12, 2022 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEF 14A 1 d429793ddef14a.htm DEF 14A Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Com

March 29, 2022 S-8

As filed with the Securities and Exchange Commission on March 29, 2022

As filed with the Securities and Exchange Commission on March 29, 2022 Registration No.

March 29, 2022 EX-4.7

Description of Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934 (incorporated by reference to Exhibit 4.7 to the Annual Report on Form 10-K for the year ended December 31, 2021).

Exhibit 4.7 DESCRIPTION OF SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 The paragraphs below describe the common stock of Vincerx Pharma, Inc. (the ?Company?). The following summary of the material terms of our common stock is not intended to be a complete summary of the rights and preferences of such common stock, and is qualified by reference to our Second

March 29, 2022 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Tables S-8 (Form Type) Vincerx Pharma, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Newly Registered Securities Fees to Be

March 29, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 29, 2022 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fil

March 29, 2022 EX-99.1

Vincerx Pharma Reports Fourth Quarter and Full Year 2021 Financial Results and Provides a Corporate Update Dosed first patient in VIP152 and pembrolizumab combination arm of study VNC-152-101 Preliminary findings in gynecologic malignancies will be p

Exhibit 99.1 Vincerx Pharma Reports Fourth Quarter and Full Year 2021 Financial Results and Provides a Corporate Update Dosed first patient in VIP152 and pembrolizumab combination arm of study VNC-152-101 Preliminary findings in gynecologic malignancies will be presented as a poster at upcoming AACR Annual Meeting in April 2022 Anticipate initiating Phase 2 studies of VIP152 in 2H2022 IND filing f

March 29, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 OR ☐ TRANSITION REPORT PUR

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-392

February 14, 2022 SC 13G/A

VINC / Vincera Pharma, Inc. / RTW INVESTMENTS, LP - VINCERX PHARMA, INC. Passive Investment

SC 13G/A 1 p22-0722sc13ga.htm VINCERX PHARMA, INC. SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* Vincerx Pharma, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 92731L106 (CUSIP Number) December 31, 2021 (Date of event which requires filing of this statement) Check

February 14, 2022 SC 13G/A

VINC / Vincera Pharma, Inc. / TANG CAPITAL PARTNERS LP - AMENDMENT NO. 1 Passive Investment

Securities and Exchange Commission Washington, DC 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No.

February 11, 2022 SC 13G/A

VINC / Vincera Pharma, Inc. / Affinity Asset Advisors, LLC - AMENDED SC 13G Passive Investment

SC 13G/A 1 vincerx-sc13ga020822.htm AMENDED SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Vincerx Pharma, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 92731L106 (CUSIP Number) Michael Hirschberg, Esq. Reitler Kailas & Rosenblatt LLP 885 Third

February 10, 2022 SC 13G

VINC / Vincera Pharma, Inc. / Rubric Capital Management LP - VINCERX PHARMA, INC. Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Vincerx Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value per share (Title of Class of Securities) 92731L106 (CUSIP Number) January 31, 2022 (Date of event which requires filing of this statement) Check the appropriate box to designate the rule pursuant to

January 28, 2022 424B3

$150,000,000 Vincerx Pharma, Inc. Debt Securities Common Stock Preferred Stock Depositary Shares

424B3 1 d204497d424b3.htm 424B3 Table of Contents Filed Pursuant to Rule 424(b)(3) Registration No. 333-262239 PROSPECTUS $150,000,000 Vincerx Pharma, Inc. Debt Securities Common Stock Preferred Stock Depositary Shares Warrants Rights We may, from time to time, offer and sell the securities identified above in one or more offerings. The aggregate initial offering price of all securities sold under

January 26, 2022 CORRESP

VINCERX PHARMA, INC. 260 Sheridan Avenue, Suite 400 Palo Alto, CA 94306 January 26, 2022

CORRESP 1 filename1.htm VINCERX PHARMA, INC. 260 Sheridan Avenue, Suite 400 Palo Alto, CA 94306 January 26, 2022 VIA FACSIMILE AND EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: Vincerx Pharma, Inc. - Registration Statement – Form S-3 File No. 333-262239 Ladies and Gentlemen: Pursuant to Rule 461 under the Securities Act of 19

January 19, 2022 EX-4.1

Form of Indenture relating to debt securities (incorporated by reference to Exhibit 4.1 to the registration Statement on Form S-3 (File No. 333-262239) filed on January 19, 2022).

Exhibit 4.1 VINCERX PHARMA, INC. TO [ ] Trustee Indenture Dated as of , 20 VINCERX PHARMA, INC. Reconciliation and tie between Trust Indenture Act of 1939 and Indenture, dated as of , 20 Trust Indenture Act Section Indenture Sections ? 310(a)(1) 609 (a)(2) 609 (a)(3) Not Applicable (a)(4) Not Applicable (a)(5) 609 (b) 608 610 ? 311(a) 613(a) (b) 613(b) (b)(2) 703(a)(2) 703(b) ? 312(a) 701 702(a) (

January 19, 2022 S-3

As filed with the Securities and Exchange Commission on January 19, 2022

Table of Contents As filed with the Securities and Exchange Commission on January 19, 2022 Registration No.

January 11, 2022 424B3

Vincerx Pharma, Inc. Up to 5,562,878 Shares of Common Stock Up to 3,295,000 Shares of Common Stock Issuable Upon Exercise of Private Warrants Up to 3,295,000 Private Warrants

Table of Contents Filed pursuant to Rule 424(b)(3) File No. 333-252589 PROSPECTUS Vincerx Pharma, Inc. Up to 5,562,878 Shares of Common Stock Up to 3,295,000 Shares of Common Stock Issuable Upon Exercise of Private Warrants Up to 3,295,000 Private Warrants This prospectus relates to the issuance by us of up to an aggregate of 3,295,000 shares of our common stock, $0.0001 par value per share, issua

January 11, 2022 424B3

Vincerx Pharma, Inc. 3,176,910 Shares Common Stock

Table of Contents Filed pursuant to Rule 424(b)(3) File No. 333-260246 PROSPECTUS Vincerx Pharma, Inc. 3,176,910 Shares Common Stock This prospectus relates to the offer and sale from time to time by the Selling Stockholders named in this prospectus of up to 3,176,910 shares of common stock. The shares of common stock have been issued pursuant to a Securities Purchase Agreement, or the Purchase Ag

January 7, 2022 POS AM

As filed with the Securities and Exchange Commission on January 6, 2022

POS AM 1 d276244dposam.htm POS AM Table of Contents As filed with the Securities and Exchange Commission on January 6, 2022 Registration No. 333-252589 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-1 ON FORM S-3 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Vincerx Pharma, Inc. (Exact Name of Registrant as Specified in it

January 7, 2022 POS AM

As filed with the Securities and Exchange Commission on January 6, 2022

Table of Contents As filed with the Securities and Exchange Commission on January 6, 2022 Registration No.

November 22, 2021 SC 13G

VINC / Vincera Pharma, Inc. / Affinity Asset Advisors, LLC - ACQUISITION OF BENEFICIAL OWNERSHIP Passive Investment

SC 13G 1 vincerx-sc13g111021.htm ACQUISITION OF BENEFICIAL OWNERSHIP UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Vincerx Pharma, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 92731L106 (CUSIP Number) Michael Hirschberg, Esq. Reitler Kailas & Rosenbla

November 12, 2021 424B3

Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants

Table of Contents Filed pursuant to Rule 424(b)(3) File No. 333-252589 PROSPECTUS SUPPLEMENT NO. 11 (to Prospectus dated February 9, 2021) Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants This prospectus supplement supplements the prospectus dated February 9, 2021 (the ?Prospectus?

November 12, 2021 424B3

Vincerx Pharma, Inc. Up to 3,500,000 Shares of Common Stock

424B3 1 d187519d424b3.htm 424B3 Table of Contents Filed pursuant to Rule 424(b)(3) File No. 333-260246 PROSPECTUS SUPPLEMENT NO. 1 (to Prospectus dated October 25, 2021) Vincerx Pharma, Inc. Up to 3,500,000 Shares of Common Stock This prospectus supplement supplements the prospectus dated October 25, 2021 (the “Prospectus”), which forms a part of our registration statement on Form S-1 (No. 333-260

November 12, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 OR ☐ TRANSITION R

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file numbe

November 12, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 12, 2021 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission

November 12, 2021 EX-99.1

Vincerx Pharma Reports Third Quarter 2021 Financial Results and Provides a Corporate Update Advancing Phase 1b study of VIP152 in MYC-driven relapsed or refractory aggressive lymphomas and advanced solid tumors Phase 1b dose escalation study of VIP15

Exhibit 99.1 Vincerx Pharma Reports Third Quarter 2021 Financial Results and Provides a Corporate Update Advancing Phase 1b study of VIP152 in MYC-driven relapsed or refractory aggressive lymphomas and advanced solid tumors Phase 1b dose escalation study of VIP152 in patients with CLL relapsed/refractory to venetoclax and BTK inhibitors on track to initiate in 2H2021 Strengthened balance sheet wit

October 26, 2021 424B3

3,500,000 Shares Vincerx Pharma, Inc. Common Stock

Table of Contents Filed pursuant to Rule 424(b)(3) File No. 333-260246 PROSPECTUS 3,500,000 Shares Vincerx Pharma, Inc. Common Stock This prospectus relates to the offer and sale from time to time by the Selling Stockholders named in this prospectus of up to 3,500,000 shares of common stock. The shares of common stock have been issued pursuant to a Securities Purchase Agreement, or the Purchase Ag

October 21, 2021 CORRESP

VINCERX PHARMA, INC. 260 Sheridan Avenue, Suite 400 Palo Alto, CA 94306 October 21, 2021

VINCERX PHARMA, INC. 260 Sheridan Avenue, Suite 400 Palo Alto, CA 94306 October 21, 2021 VIA FACSIMILE AND EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: Vincerx Pharma, Inc. - Registration Statement – Form S-1 File No. 333-260246 Ladies and Gentlemen: Pursuant to Rule 461 under the Securities Act of 1933, as amended, Vincerx

October 14, 2021 EX-10.11

Executive Employment Agreement by and between the Company and Xiaoming Zhang, dated December 23, 2020.

Exhibit 10.11 EXECUTIVE EMPLOYMENT AGREEMENT This EXECUTIVE EMPLOYMENT AGREEMENT (the ?Agreement?), dated as of December 23, 2020, is by and between Vincera Pharma, Inc., a Delaware corporation (the ?Company?), and Xiaoming Zhang (?Executive?). WHEREAS, the Company wishes to retain the services of Executive and Executive wishes to be employed by the Company on the terms and subject to the conditio

October 14, 2021 S-1

As filed with the Securities and Exchange Commission on October 14, 2021 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Vincerx Pharma, In

Table of Contents As filed with the Securities and Exchange Commission on October 14, 2021 Registration No.

October 14, 2021 EX-10.10

Executive Employment Agreement by and between the Company and Sooin Hwang, dated December 23, 2020 (incorporated by reference to Exhibit 10.10 to the Registration Statement on Form S-1 (File No. 333-260246) filed on October 14, 2021).

Exhibit 10.10 EXECUTIVE EMPLOYMENT AGREEMENT This EXECUTIVE EMPLOYMENT AGREEMENT (the ?Agreement?), dated as of December 23, 2020, is by and between Vincera Pharma, Inc., a Delaware corporation (the ?Company?), and Sooin Hwang, PhD (?Executive?). WHEREAS, the Company wishes to retain the services of Executive and Executive wishes to be employed by the Company on the terms and subject to the condit

September 28, 2021 SC 13G

VINC / Vincera Pharma, Inc. / Flynn James E Passive Investment

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No.

September 17, 2021 424B3

Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants

Filed pursuant to Rule 424(b)(3) Registration No. 333-252589 PROSPECTUS SUPPLEMENT NO. 10 (to Prospectus dated February 9, 2021) Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants This prospectus supplement supplements the prospectus dated February 9, 2021 (the ?Prospectus?), which f

September 16, 2021 EX-4.1

Registration Rights Agreement by and among the Company and the Investors party thereto, dated September 15, 2021 (incorporated by reference to Exhibit 4.1 to the Company’s Current Report on Form 8-K filed on September 16, 2021).

Exhibit 4.1 REGISTRATION RIGHTS AGREEMENT This REGISTRATION RIGHTS AGREEMENT (this ?Agreement?) is made and entered into as of September 15, 2021 by and among Vincerx Pharma, Inc., a Delaware corporation (the ?Company?), and the ?Investors? named in that certain Securities Purchase Agreement by and among the Company and the Investors, dated as of September 15, 2021 (the ?Purchase Agreement?). Capi

September 16, 2021 EX-99.1

Vincerx Pharma Announces $50 Million Private Placement Strengthened financial position extends expected cash runway into 2023

Exhibit 99.1 Vincerx Pharma Announces $50 Million Private Placement Strengthened financial position extends expected cash runway into 2023 PALO ALTO, Calif., September 16, 2021 (GLOBE NEWSWIRE) ? Vincerx Pharma, Inc. (Nasdaq: VINC), a biopharmaceutical company aspiring to address the unmet medical needs of patients with cancer through paradigm-shifting therapeutics, announced that it has entered i

September 16, 2021 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 15, 2021 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission

September 16, 2021 EX-10.1

Securities Purchase Agreement by and among the Company and the Investors party thereto, dated September 15, 2021 (incorporated by reference to Exhibit 10.1 to the Company’s Current Report on Form 8-K filed on September 16, 2021).

Exhibit 10.1 SECURITIES PURCHASE AGREEMENT This SECURITIES PURCHASE AGREEMENT (this ?Agreement?) is made and entered into as of September 15, 2021 by and among Vincerx Pharma, Inc., a Delaware corporation (the ?Company?), and the Investors identified on Exhibit A attached hereto (each an ?Investor? and collectively the ?Investors?). RECITALS A. The Company and the Investors are executing and deliv

August 12, 2021 424B3

Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants

Table of Contents Filed pursuant to Rule 424(b)(3) Registration No. 333-252589 PROSPECTUS SUPPLEMENT NO. 9 (to Prospectus dated February 9, 2021) Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants This prospectus supplement supplements the prospectus dated February 9, 2021 (the ?Pros

August 12, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021 OR ☐ TRANSITION REPORT

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001

August 12, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 12, 2021 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fi

August 12, 2021 EX-99.1

Vincerx Pharma Reports Second Quarter 2021 Financial Results and Provides a Corporate Update First patient dosed in Phase 1b study of VIP152 in MYC-driven relapsed or refractory aggressive lymphomas and advanced solid tumors Phase 1b dose escalation

Exhibit 99.1 Vincerx Pharma Reports Second Quarter 2021 Financial Results and Provides a Corporate Update First patient dosed in Phase 1b study of VIP152 in MYC-driven relapsed or refractory aggressive lymphomas and advanced solid tumors Phase 1b dose escalation study of VIP152 in patients with CLL relapsed/refractory to venetoclax and BTK inhibitors on track to initiate in 2H2021 PALO ALTO, Calif

August 4, 2021 SC 13G

VINC / Vincera Pharma, Inc. / SAGE RHINO CAPITAL LLC - SAGE RHINO CAPITAL, LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Vincerx Pharma Inc (Name of Issuer) Common Stock (Title of Class of Securities) 92731L106 (CUSIP Number) March 04, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: [ ] Rul

June 11, 2021 EX-99.1

Vincerx Pharma, Inc. 2021 Employee Stock Purchase Plan (incorporated by reference to Exhibit 99.1 to the Registration Statement on Form S-8 (File No. 333-257042) filed on June 11, 2021).

Table of Contents Exhibit 99.1 VINCERX PHARMA, INC. 2021 EMPLOYEE STOCK PURCHASE PLAN (Adopted by the Board of Directors on February 11, 2021) (Approved by the Stockholders on May 13, 2021) (Effective on May 13, 2021) Table of Contents Table of Contents Page SECTION 1 Purpose Of The Plan 4 SECTION 2 Definitions 4 (a) ?Board? 4 (b) ?Code? 4 (c) ?Committee? 4 (d) ?Company? 4 (e) ?Compensation? 4 (f)

June 11, 2021 S-8

As filed with the Securities and Exchange Commission on June 11, 2021

As filed with the Securities and Exchange Commission on June 11, 2021 Registration No.

May 17, 2021 424B3

Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants

Table of Contents Filed pursuant to Rule 424(b)(3) Registration No. 333-252589 PROSPECTUS SUPPLEMENT NO. 8 (to Prospectus dated February 9, 2021) Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants This prospectus supplement supplements the prospectus dated February 9, 2021 (the ?Pros

May 17, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 17, 2021 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission File

May 17, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 00

May 17, 2021 EX-99.1

Vincerx Pharma Reports First Quarter 2021 Financial Results and Provides a Corporate Update Phase 1b dose escalation study of VIP152 in patients with CLL relapsed/refractory to venetoclax and BTK inhibitors on track to initiate in 2H2021 First patien

Exhibit 99.1 Vincerx Pharma Reports First Quarter 2021 Financial Results and Provides a Corporate Update Phase 1b dose escalation study of VIP152 in patients with CLL relapsed/refractory to venetoclax and BTK inhibitors on track to initiate in 2H2021 First patient in Phase 1b Study of VIP152 in MYC-driven R/R aggressive lymphomas and advanced solid tumors expected 2Q 2021 Phase 1 VIP152 dose-escal

May 14, 2021 424B3

Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants

Table of Contents Filed pursuant to Rule 424(b)(3) Registration No. 333-252589 PROSPECTUS SUPPLEMENT NO. 7 (to Prospectus dated February 9, 2021) Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants This prospectus supplement supplements the prospectus dated February 9, 2021 (the ?Pros

May 14, 2021 424B3

Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants

Filed pursuant to Rule 424(b)(3) Registration No. 333-252589 PROSPECTUS SUPPLEMENT NO. 6 (to Prospectus dated February 9, 2021) Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants This prospectus supplement supplements the prospectus dated February 9, 2021 (the ?Prospectus?), which fo

May 14, 2021 10-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K/A (Mark One) Amendment No. 1

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K/A (Mark One) Amendment No. 1 ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2020 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission f

May 14, 2021 8-K

Non-Reliance on Previously Issued Financial Statements or a Related Audit Report or Completed Interim Review, Results of Operations and Financial Condition, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 13, 2021 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission File

May 6, 2021 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 5, 2021 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission File N

May 6, 2021 424B3

Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants

Filed pursuant to Rule 424(b)(3) Registration No. 333-252589 PROSPECTUS SUPPLEMENT NO. 5 (to Prospectus dated February 9, 2021) Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants This prospectus supplement supplements the prospectus dated February 9, 2021 (the ?Prospectus?), which fo

April 20, 2021 424B3

Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants

Filed pursuant to Rule 424(b)(3) Registration No. 333-252589 PROSPECTUS SUPPLEMENT NO. 4 (to Prospectus dated February 9, 2021) Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants This prospectus supplement supplements the prospectus dated February 9, 2021 (the ?Prospectus?), which fo

April 20, 2021 EX-99.1

Vincerx Pharma Announces FDA Clearance of IND for Phase 1b Study of VIP152 in Chronic Lymphocytic Leukemia and Richter Syndrome Dose escalation study in patients with CLL relapsed/refractory to venetoclax and BTK inhibitors on track to initiate in 2H

Exhibit 99.1 Vincerx Pharma Announces FDA Clearance of IND for Phase 1b Study of VIP152 in Chronic Lymphocytic Leukemia and Richter Syndrome Dose escalation study in patients with CLL relapsed/refractory to venetoclax and BTK inhibitors on track to initiate in 2H2021 Vincerx?s second clinical program for potential best-in-class CDK9 inhibitor First patient in Phase 1b Study in MYC-driven R/R aggre

April 20, 2021 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 20, 2021 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fil

April 12, 2021 DEF 14A

- DEF 14A

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14

April 5, 2021 EX-99.2

NOTICE OF REDEMPTION OF CERTAIN WARRANTS (CUSIP 92731L114)

Exhibit 99.2 April 5, 2021 NOTICE OF REDEMPTION OF CERTAIN WARRANTS (CUSIP 92731L114) Dear Public Warrant Holder, Vincerx Pharma, Inc. (the ?Company?) hereby gives notice that it is redeeming, at 5:00 p.m. New York City time on May 5, 2021 (the ?Redemption Date?), all of the Company?s outstanding public warrants (the ?Public Warrants?) to purchase shares of the Company?s common stock, $0.0001 par

April 5, 2021 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 2, 2021 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission File

April 5, 2021 424B3

Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants

Filed pursuant to Rule 424(b)(3) Registration No. 333-252589 PROSPECTUS SUPPLEMENT NO. 3 (to Prospectus dated February 9, 2021) Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants This prospectus supplement supplements the prospectus dated February 9, 2021 (the ?Prospectus?), which fo

April 5, 2021 EX-3.1

Amended and Restated Bylaws (incorporated by reference to Exhibit 3.1 to the Current Report on Form 8-K filed on April 5, 2021).

Exhibit 3.1 AMENDED AND RESTATED BYLAWS OF VINCERX PHARMA, INC. (formerly known as Vincera Pharma, Inc.) (a Delaware corporation) (As amended as of April 2, 2021) TABLE OF CONTENTS Page ARTICLE 1 Offices 1 1.1 Registered Office 1 1.2 Other Offices 1 ARTICLE 2 Meeting of Stockholders 1 2.1 Place of Meeting 1 2.2 Annual Meeting 1 2.3 Special Meetings 3 2.4 Notice of Meetings 3 2.5 List of Stockholde

April 5, 2021 EX-99.1

Vincerx Pharma Announces Redemption of Public Warrants

Exhibit 99.1 Vincerx Pharma Announces Redemption of Public Warrants PALO ALTO, California, April 5, 2021 ? Vincerx Pharma, Inc. (Nasdaq: VINC) (the ?Company?), today announced that it will redeem all of its outstanding public warrants (the ?Public Warrants?) to purchase shares of the Company?s common stock, $0.0001 par value per share (?Common Stock?), that were issued under the Warrant Agreement,

March 24, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 23, 2021 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission Fil

March 24, 2021 EX-99.1

Vincerx Pharma Reports Fourth Quarter and Full Year 2020 Financial Results and Provides a Corporate Update License agreement with Bayer AG secures oncology portolio including clinical-stage PTEFb/CDK9 inhibitor with encouraging Phase 1 activity Succe

Exhibit 99.1 Vincerx Pharma Reports Fourth Quarter and Full Year 2020 Financial Results and Provides a Corporate Update License agreement with Bayer AG secures oncology portolio including clinical-stage PTEFb/CDK9 inhibitor with encouraging Phase 1 activity Successful completion of business combination transaction, raising approximately $62 million Strengthened leadership with appointments of Chie

March 22, 2021 EX-4.6

Exhibit 4.6

Exhibit 4.6 DESCRIPTION OF SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 The paragraphs below describe the units, common stock, and public warrants of Vincerx Pharma, Inc. (the ?Company?). The following summary of the material terms of our securities is not intended to be a complete summary of the rights and preferences of such securities, and is qualified by

March 22, 2021 EX-10.8

Executive Employment Agreement by and between the Company and Tom C. Thomas, dated January 27, 2021 (incorporated by reference to Exhibit 10.8 to the Annual Report on Form 10-K for the year ended December 31, 2020).

EX-10.8 4 d132337dex108.htm EX-10.8 Exhibit 10.8 EXECUTIVE EMPLOYMENT AGREEMENT This EXECUTIVE EMPLOYMENT AGREEMENT (the “Agreement”), dated as of January 27, 2021, is by and between Vincerx Pharma, Inc., a Delaware corporation (the “Company”), and Tom C. Thomas (“Executive”). WHEREAS, the Company wishes to retain the services of Executive and Executive wishes to be employed by the Company on the

March 22, 2021 EX-10.7

Executive Employment Agreement by and between the Company and Hermes Garban, dated December 23, 2020.

Exhibit 10.7 EXECUTIVE EMPLOYMENT AGREEMENT This EXECUTIVE EMPLOYMENT AGREEMENT (the ?Agreement?), dated as of December 23, 2020, is by and between Vincera Pharma, Inc., a Delaware corporation (the ?Company?), and Hermes Garban (?Executive?). WHEREAS, the Company wishes to retain the services of Executive and Executive wishes to be employed by the Company on the terms and subject to the conditions

March 22, 2021 S-8

- S-8

As filed with the Securities and Exchange Commission on March 22, 2021 Registration No.

March 22, 2021 424B3

Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants

Table of Contents Filed pursuant to Rule 424(b)(3) Registration No. 333-252589 PROSPECTUS SUPPLEMENT NO. 2 (to Prospectus dated February 9, 2021) Vincerx Pharma, Inc. Up to 6,112,884 Shares of Common Stock Up to 6,851,883 Shares of Common Stock Issuable Upon Exercise of Warrants Up to 3,570,000 Private Warrants This prospectus supplement supplements the prospectus dated February 9, 2021 (the ?Pros

March 22, 2021 10-K

Annual Report - 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2020 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-392

February 17, 2021 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 17, 2021 Vincerx Pharma, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39244 83-3197402 (State or Other Jurisdiction of Incorporation) (Commission

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