VTR / Ventas, Inc. - Pengajuan SECLaporan Tahunan, Pernyataan Proksi

List of Guarantors and Issuers of Guaranteed Securities

Exhibit 22 List of Guarantors and Issuers of Guaranteed Securities As of June 30, 2025, Ventas, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROMTO Commission file number: 1-10989 Ventas, Inc.

Ventas Reports 2025 Second Quarter Results

Exhibit 99.1 Ventas, Inc. 300 North LaSalle Street, Suite 1600 Chicago, Illinois 60654 (877) 4-VENTAS www.ventasreit.com Contact: BJ Grant (877) 4-VENTAS Ventas Reports 2025 Second Quarter Results CHICAGO – Ventas, Inc. (NYSE: VTR) (“Ventas” or the “Company”) today reported results for the second quarter ended June 30, 2025. CEO Remarks “The Company delivered strong earnings growth in the second q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 30, 2025 Ventas, Inc. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 30, 2025 Ventas, Inc. (Exact name of registrant as specified in its charter) Delaware 001-10989 61-1055020 (State or other jurisdiction of incorporation) (Commission File Number)

Amendment No. 1 to the Sales Agreement, dated June 13, 2025, among Ventas, Inc. and the Agents and Forward Purchasers named therein.

Exhibit 1.1 Ventas, Inc. Common Stock ($0.25 par value) AMENDMENT NO. 1 TO ATM SALES AGREEMENT June 13, 2025 BofA Securities, Inc. BBVA Securities Inc. BNP Paribas Securities Corp. BNY Mellon Capital Markets, LLC Citigroup Global Markets Inc. Credit Agricole Securities (USA) Inc. Jefferies LLC J.P. Morgan Securities LLC Mizuho Securities USA LLC Morgan Stanley & Co. LLC MUFG Securities Americas In

Table 1: Newly Registered and Carry Forward Securities

Calculation of Filing Fee Tables S-3 Ventas, Inc. Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Carry Forward Form Type Carry Forward File Number Carry Forward Initial Effective Date Filing

$2,250,000,000 Ventas, Inc. Common Stock

TABLE OF CONTENTS  Filed Pursuant to Rule 424(b)(5)  Registration Statement No. 333-277185 PROSPECTUS SUPPLEMENT (To prospectus dated February 20, 2024) $2,250,000,000 Ventas, Inc. Common Stock On June 13, 2025, we entered into Amendment No. 1 (the “Amendment”) to our ATM Sales Agreement, dated September 18, 2024 (as amended from time to time, the “Sales Agreement”), with BofA Securities, Inc., BB

As filed with the Securities and Exchange Commission on June 13, 2025

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on June 13, 2025 Registration No.

Filing Fee Table.

Calculation of Filing Fee Tables S-3 Ventas, Inc. Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Carry Forward Form Type Carry Forward File Number Carry Forward Initial Effective Date Filing

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): June 13, 2025 VENTAS, INC. (Exact Name of Registrant as Specified in Its Charter) DELAWARE 61-1055020 (State or Other Jurisdiction of Incorporation or Organization) (I.R.S. Employer I

Tenth Supplemental Indenture, dated June 3, 2025, among Ventas Realty, Limited Partnership, as Issuer, Ventas, Inc., as Guarantor, and U.S. Bank Trust Company, National Association (successor to U.S. Bank National Association), as Trustee (including the form of the 5.100% Senior Notes due 2032).

Exhibit 4.2 Execution Version TENTH SUPPLEMENTAL INDENTURE by and among Ventas Realty, Limited Partnership, as Issuer, Ventas, Inc., as Guarantor and U.S. Bank Trust Company, National Association, as Trustee $500,000,000 5.100% Senior Notes due 2032 Dated as of June 3, 2025 Supplement to Indenture dated as of February 23, 2018 (Senior Debt Securities) TABLE OF CONTENTS Page Article I Creation of t

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 29, 2025 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Number)

Underwriting Agreement, dated May 29, 2025, among Ventas Realty, Limited Partnership, Ventas, Inc. and the Underwriters named therein, relating to the 5.100% Senior Notes due 2032.

Exhibit 1.1 Execution Version VENTAS REALTY, LIMITED PARTNERSHIP $500,000,000 5.100% Senior Notes due 2032 UNDERWRITING AGREEMENT Dated May 29, 2025 BofA Securities, Inc. BNP Paribas Securities Corp. J.P. Morgan Securities LLC Morgan Stanley & Co. LLC UNDERWRITING AGREEMENT May 29, 2025 BofA Securities, Inc. One Bryant Park New York, New York 10036 BNP Paribas Securities Corp. 787 Seventh Ave New

Ventas Realty, Limited Partnership $500,000,000 5.100% Senior Notes due 2032 Fully and unconditionally guaranteed by Ventas, Inc.

TABLE OF CONTENTS  Filed Pursuant to Rule 424(b)(2)  Registration Statement Nos. 333-277185 and 333-277185-01 PROSPECTUS SUPPLEMENT (To prospectus dated February 20, 2024) Ventas Realty, Limited Partnership $500,000,000 5.100% Senior Notes due 2032 Fully and unconditionally guaranteed by Ventas, Inc. Ventas Realty, Limited Partnership (the “issuer”) is offering $500 million aggregate principal amo

Table 1: Newly Registered and Carry Forward Securities

Calculation of Filing Fee Tables S-3 Ventas, Inc. Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Carry Forward Form Type Carry Forward File Number Carry Forward Initial Effective Date Filing

PRICING TERM SHEET VENTAS REALTY, LIMITED PARTNERSHIP Fully and unconditionally guaranteed by Ventas, Inc. Terms applicable to $500,000,000 5.100% Senior Notes due 2032 Dated: May 29, 2025

Issuer Free Writing Prospectus Filed pursuant to Rule 433 Supplementing the Preliminary Prospectus Supplement dated May 29, 2025 and the Prospectus dated February 20, 2024 Registration Nos.

Subject to Completion Preliminary Prospectus Supplement dated May 29, 2025

TABLE OF CONTENTS The information in this preliminary prospectus supplement is not complete and may be changed.

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Material Modification to Rights of Security Holders, Submission of Matters to a Vote of Security Holders, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 13, 2025 VENTAS, INC. (Exact Name of Registrant as Specified in Its Charter) DELAWARE 61-1055020 (State or Other Jurisdiction of Incorporation or Organization) (I.R.S. Employer Id

Certificate of Amendment (Exculpation Amendment)

  Exhibit 3.2   CERTIFICATE OF AMENDMENT  OF  THE AMENDED AND RESTATED CERTIFICATE OF INCORPORATION  OF  VENTAS, INC.  Pursuant to Section 242  of the General Corporation Law of the State of Delaware   Ventas, Inc. (the “Corporation”), a corporation duly organized and existing under and by virtue of the General Corporation Law of the State of Delaware (the “DGCL”), DOES HEREBY CERTIFY:   1.       

Certificate of Amendment (Authorized Share Amendment)

  Exhibit 3.1   CERTIFICATE OF AMENDMENT  OF  THE AMENDED AND RESTATED CERTIFICATE OF INCORPORATION  OF  VENTAS, INC.  Pursuant to Section 242  of the General Corporation Law of the State of Delaware   Ventas, Inc. (the “Corporation”), a corporation duly organized and existing under and by virtue of the General Corporation Law of the State of Delaware (the “DGCL”), DOES HEREBY CERTIFY:   1.       

Restated Certificate of Incorporation of Ventas, Inc.

  Exhibit 3.3   RESTATED CERTIFICATE OF INCORPORATION OF VENTAS, INC.   Ventas, Inc., a corporation organized and existing under the laws of the State of Delaware (the “Corporation”), hereby certifies as follows:   FIRST: The name of the Corporation is Ventas, Inc., formerly Vencor, Inc. The date of filing of its original Certificate of Incorporation with the Secretary of State was June 22, 1987.

FIRST AMENDMENT TO CREDIT AND GUARANTY AGREEMENT

Exhibit 10.3 FIRST AMENDMENT TO CREDIT AND GUARANTY AGREEMENT FIRST AMENDMENT TO CREDIT AND GUARANTY AGREEMENT, dated as of April 29, 2025 (this “Amendment”), is entered into among Ventas Realty, Limited Partnership, a Delaware limited partnership (the “Borrower”) and Ventas Inc., a Delaware corporation (the “Guarantor”), the Lenders from time to time party thereto, and Bank of America, N.A., as a

FIRST AMENDMENT TO FOURTH AMENDED AND RESTATED CREDIT AND GUARANTY AGREEMENT

Exhibit 10.1 FIRST AMENDMENT TO FOURTH AMENDED AND RESTATED CREDIT AND GUARANTY AGREEMENT FIRST AMENDMENT TO FOURTH AMENDED AND RESTATED CREDIT AND GUARANTY AGREEMENT, dated as of April 29, 2025 (this “Amendment”), is entered into among Ventas Realty, Limited Partnership, a Delaware limited partnership (the “Parent Borrower”), Ventas SSL Ontario II, Inc., an Ontario corporation (“Ventas SSL”), Ven

List of Guarantors and Issuers of Guaranteed Securities

Exhibit 22 List of Guarantors and Issuers of Guaranteed Securities As of March 31, 2025, Ventas, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROMTO Commission file number: 1-10989 Ventas, Inc.

FIRST AMENDMENT TO CREDIT AND GUARANTY AGREEMENT

Exhibit 10.2 FIRST AMENDMENT TO CREDIT AND GUARANTY AGREEMENT FIRST AMENDMENT TO CREDIT AND GUARANTY AGREEMENT, dated as of April 29, 2025 (this “Amendment”), is entered into among Ventas Realty, Limited Partnership, a Delaware limited partnership (the “Borrower”) and Ventas Inc., a Delaware corporation (the “Guarantor”), the Lenders from time to time party thereto, and Bank of America, N.A., as a

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 30, 2025 (April 29, 2025) Ventas, Inc. (Exact name of registrant as specified in its charter) Delaware 001-10989 61-1055020 (State or other jurisdiction of incorporation) (Commi

Ventas Reports 2025 First Quarter Results

Exhibit 99.1 Ventas, Inc. 300 North LaSalle Street, Suite 1600 Chicago, Illinois 60654 (877) 4-VENTAS www.ventasreit.com Contact: BJ Grant (877) 4-VENTAS Ventas Reports 2025 First Quarter Results CHICAGO – Ventas, Inc. (NYSE: VTR) (“Ventas” or the “Company”) today reported results for the first quarter ended March 31, 2025. CEO Remarks “Ventas delivered a strong first quarter of 2025, as we execut

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 þ Filed by the Registrant o Filed by a party other than the Registrant CHECK THE APPROPRIATE BOX: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) þ Filed by the Registrant o Filed by a party other than the Registrant CHECK THE APPROPRIATE BOX: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) þ Filed by the Registrant o Filed by a party other than the Registrant CHECK THE APPROPRIATE BOX: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Defin

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) þ Filed by the Registrant o Filed by a party other than the Registrant CHECK THE APPROPRIATE BOX: þ Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14

Ventas, Inc. Securities Trading Policy Adopted as amended 3.11.2022

Exhibit 19 Ventas, Inc. Securities Trading Policy Adopted as amended 3.11.2022 1INTRODUCTORY STATEMENT As a publicly traded company, Ventas, Inc. (together with its affiliates, the “Company”) has certain legal and ethical responsibilities with respect to the market for its securities and the confidentiality of information about the Company’s business. In this regard, the Company depends upon the c

List of Guarantors and Issuers of Guaranteed Securities

Exhibit 22 List of Guarantors and Issuers of Guaranteed Securities As of December 31, 2024, Ventas, Inc.

SUBSIDIARIES OF VENTAS, INC.

Exhibit 21 SUBSIDIARIES OF VENTAS, INC. Entity Name Jurisdiction of Organization or Formation 1425 Hunt Club, LLC Delaware 1445 Hunt Club, LLC Delaware 14851 Yorba Street, LLC Delaware 200 Andrews, LLC South Carolina 2010 Union Limited Partnership Washington 311 South Sarah, LLC Delaware 3737 Market Investment Fund, LLC Missouri 4220 Duncan Holding, LLC Delaware 4220 Duncan Investment Fund, LLC De

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the year ended December 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission file number: 1-10989 Ventas, Inc. (Exact Nam

Exhibit 4.27

Exhibit 4.28 DESCRIPTION OF THE REGISTRANT’S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 The summary set forth below describes the general terms and provisions of the common stock of Ventas, Inc. The following description is only a summary and does not purport to be complete and is subject to and qualified in its entirety by reference to the Amended and Rest

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 12, 2025 Ventas, Inc. (Exact name of registrant as specified in its charter) Delaware 001-10989 61-1055020 (State or other jurisdiction of incorporation) (Commission File Num

Ventas Reports 2024 Full Year Results, Provides 2025 Outlook and Increases Dividend

Exhibit 99.1 Ventas, Inc. 300 North LaSalle Street, Suite 1600 Chicago, Illinois 60654 (877) 4-VENTAS www.ventasreit.com Contact: BJ Grant (877) 4-VENTAS Ventas Reports 2024 Full Year Results, Provides 2025 Outlook and Increases Dividend CHICAGO – Ventas, Inc. (NYSE: VTR) (“Ventas” or the “Company”) today reported results for the full year and fourth quarter ended December 31, 2024. CEO Remarks “V

10,600,000 Shares Ventas, Inc. Common Stock

TABLE OF CONTENTS  Filed Pursuant to Rule 424(b)(2)  Registration Statement No. 333-277185 PROSPECTUS SUPPLEMENT (To prospectus dated February 20, 2024) 10,600,000 Shares Ventas, Inc. Common Stock We are offering 10,600,000 shares of our common stock. Ventas, Inc. is entering into a forward sale agreement with Wells Fargo Bank, National Association or its affiliate (the “forward purchaser”), in re

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): November 13, 2024 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Num

Table 1: Newly Registered and Carry Forward Securities

Calculation of Filing Fee Tables S-3 Ventas, Inc. Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Carry Forward Form Type Carry Forward File Number Carry Forward Initial Effective Date Filing

Forward Sale Agreement, dated as of November 13, 2024, between Ventas, Inc. and Wells Fargo Bank, National Association.

Exhibit 1.2 Date: November 13, 2024 To: Ventas, Inc. 353 N. Clark Street, Suite 3300 Chicago, Illinois 60654 Attn: Son Nguyen, SVP, Capital Markets & Treasury Telephone: 312.268.4185 Email: From: Wells Fargo Bank, National Association 30 Hudson Yards New York, NY 10001-2170 Email: Re: Registered Forward Transaction Ladies and Gentlemen: The purpose of this letter agreement (this “Confirmation”) is

Underwriting Agreement, dated as of November 13, 2024, among Ventas, Inc., Wells Fargo Securities, LLC, as underwriter, Wells Fargo Bank, National Association, as forward purchaser and Wells Fargo Securities, LLC, as forward seller.

Exhibit 1.1 Execution Version VENTAS, INC. 10,600,000 Shares of Common Stock UNDERWRITING AGREEMENT Dated November 13, 2024 Wells Fargo Securities, LLC UNDERWRITING AGREEMENT November 13, 2024 Wells Fargo Securities, LLC 500 West 33rd Street New York, New York 10001 Ladies and Gentlemen: Ventas, Inc., a Delaware corporation (the “Company”), and Wells Fargo Securities, LLC, in its capacity as selle

ARDT / Ardent Health Partners, Inc. / Ventas, Inc. - SC 13G Passive Investment

SC 13G 1 tm2428527d1sc13g.htm SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Ardent Health Partners, Inc. (Name of Issuer) Common Stock, $0.01 par value per share (Title of Class of Securities) 03980N107 (CUSIP Number) July 17, 2024 (Date of Event which Requires Filing of this Statement) Check

Subject to Completion Preliminary Prospectus Supplement dated November 13, 2024

TABLE OF CONTENTS The information in this preliminary prospectus supplement is not complete and may be changed.

BKD / Brookdale Senior Living Inc. / Ventas, Inc. - SC 13G/A Passive Investment

SC 13G/A 1 tm2428527d2sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* Brookdale Senior Living Inc. (Name of Issuer) Common stock, $0.01 par value per share (Title of Class of Securities) 112463104 (CUSIP Number) August 26, 2024 (Date of Event which Requires Filing of this Stateme

List of Guarantors and Issuers of Guaranteed Securities

Exhibit 22 List of Guarantors and Issuers of Guaranteed Securities As of September 30, 2024, Ventas, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROMTO Commission file number: 1-10989 Ventas,

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 30, 2024 Ventas, Inc. (Exact name of registrant as specified in its charter) Delaware 001-10989 61-1055020 (State or other jurisdiction of incorporation) (Commission File Numb

Ventas Reports 2024 Third Quarter Results

Exhibit 99.1 Ventas, Inc. 353 North Clark Street, Suite 3300 Chicago, Illinois 60654 (877) 4-VENTAS www.ventasreit.com Contact: BJ Grant (877) 4-VENTAS Ventas Reports 2024 Third Quarter Results CHICAGO – Ventas, Inc. (NYSE: VTR) (“Ventas” or the “Company”) today reported results for the third quarter ended September 30, 2024. CEO Remarks “Ventas delivered another strong quarter executing on our fo

VTR / Ventas, Inc. / JPMORGAN CHASE & CO - FILING VENTAS, INC. Passive Investment

SC 13G 1 VentasInc.htm FILING VENTAS, INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Ventas, Inc. (Name of Issuer) Common Stock $0.25 par value (Title of Class of Securities) 92276F100 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of this Statement) Check the appropriate

ATM Sales Agreement, dated September 18, 2024, among Ventas, Inc. and the Agents and Forward Purchasers named therein.

Exhibit 1.1 Ventas, Inc. Common Stock ($0.25 par value) ATM SALES AGREEMENT September 18, 2024 BofA Securities, Inc. BBVA Securities Inc. BNP Paribas Securities Corp. BNY Mellon Capital Markets, LLC Citigroup Global Markets Inc. Credit Agricole Securities (USA) Inc. Jefferies LLC J.P. Morgan Securities LLC Mizuho Securities USA LLC Morgan Stanley & Co. LLC MUFG Securities Americas Inc. RBC Capital

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): September 18, 2024 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Nu

$2,000,000,000 Ventas, Inc. Common Stock

TABLE OF CONTENTS  Filed Pursuant to Rule 424(b)(5)  Registration Statement No. 333-277185 PROSPECTUS SUPPLEMENT (To prospectus dated February 20, 2024) $2,000,000,000 Ventas, Inc. Common Stock On September 18, 2024, we entered into an ATM Sales Agreement (the “Sales Agreement”) with BofA Securities, Inc., BBVA Securities Inc., BNP Paribas Securities Corp., BNY Mellon Capital Markets, LLC, Citigro

Table 1: Newly Registered and Carry Forward Securities

Calculation of Filing Fee Tables S-3 Ventas, Inc. Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Carry Forward Form Type Carry Forward File Number Carry Forward Initial Effective Date Filing

Underwriting Agreement, dated September 5, 2024, among Ventas Realty, Limited Partnership, Ventas, Inc. and the Underwriters named therein, relating to the 5.000% Senior Notes due 2035.

Exhibit 1.1 Execution Version VENTAS REALTY, LIMITED PARTNERSHIP $550,000,000 5.000% Senior Notes due 2035 UNDERWRITING AGREEMENT Dated September 5, 2024 Wells Fargo Securities, LLC MUFG Securities Americas Inc. PNC Capital Markets LLC Truist Securities, Inc. UNDERWRITING AGREEMENT September 5, 2024 Wells Fargo Securities, LLC 550 South Tryon Street Charlotte, North Carolina 28202 MUFG Securities

Ninth Supplemental Indenture, dated September 9, 2024, among Ventas Realty, Limited Partnership, as Issuer, Ventas, Inc., as Guarantor, and U.S. Bank Trust Company, National Association (successor to U.S. Bank National Association), as Trustee (including the form of the 5.000% Senior Notes due 2035).

Exhibit 4.2 Execution Version NINTH SUPPLEMENTAL INDENTURE by and among Ventas Realty, Limited Partnership, as Issuer, Ventas, Inc., as Guarantor and U.S. Bank Trust Company, National Association, as Trustee $550,000,000 5.000% Senior Notes due 2035 Dated as of September 9, 2024 Supplement to Indenture dated as of February 23, 2018 (Senior Debt Securities) TABLE OF CONTENTS Page ARTICLE I CREATION

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): September 9, 2024 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Num

Table 1: Newly Registered and Carry Forward Securities

Calculation of Filing Fee Tables S-3 Ventas, Inc. Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Carry Forward Form Type Carry Forward File Number Carry Forward Initial Effective Date Filing

Ventas Realty, Limited Partnership $550,000,000 5.000% Senior Notes due 2035 Fully and unconditionally guaranteed by Ventas, Inc.

TABLE OF CONTENTS  Filed Pursuant to Rule 424(b)(2)  Registration Statement Nos. 333-277185 and 333-277185-01 PROSPECTUS SUPPLEMENT (To prospectus dated February 20, 2024) Ventas Realty, Limited Partnership $550,000,000 5.000% Senior Notes due 2035 Fully and unconditionally guaranteed by Ventas, Inc. Ventas Realty, Limited Partnership (the “issuer”) is offering $550 million aggregate principal amo

PRICING TERM SHEET VENTAS REALTY, LIMITED PARTNERSHIP Fully and unconditionally guaranteed by Ventas, Inc. Terms applicable to $ 550,000,000 5.000% Senior Notes due 2035 Dated: September 5, 2024

Issuer Free Writing Prospectus Filed pursuant to Rule 433 Supplementing the Preliminary Prospectus Supplement dated September 5, 2024 and the Prospectus dated February 20, 2024 Registration Nos.

Subject to Completion Preliminary Prospectus Supplement dated September 5, 2024

TABLE OF CONTENTS The information in this preliminary prospectus supplement is not complete and may be changed.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROMTO Commission file number: 1-10989 Ventas, Inc.

List of Guarantors and Issuers of Guaranteed Securities

Exhibit 22 List of Guarantors and Issuers of Guaranteed Securities As of June 30, 2024, Ventas, Inc.

Ventas Reports 2024 Second Quarter Results

Exhibit 99.1 Ventas, Inc. 353 North Clark Street, Suite 3300 Chicago, Illinois 60654 (877) 4-VENTAS www.ventasreit.com Contact: BJ Grant (877) 4-VENTAS Ventas Reports 2024 Second Quarter Results CHICAGO – Ventas, Inc. (NYSE: VTR) (“Ventas” or the “Company”) today reported results for the second quarter ended June 30, 2024. CEO Remarks “We started 2024 with momentum, which continued in the second q

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 1, 2024 Ventas, Inc. (Exact name of registrant as specified in its charter) Delaware 001-10989 61-1055020 (State or other jurisdiction of incorporation) (Commission File Number

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 14, 2024 Ventas, Inc. (Exact name of registrant as specified in its charter) Delaware 001-10989 61-1055020 (State or other jurisdiction of incorporation) (Commission File Number)

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 13, 2024 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Number)

Eighth Supplemental Indenture, dated May 13, 2024, among Ventas Realty, Limited Partnership, as Issuer, Ventas, Inc., as Guarantor, and U.S. Bank Trust Company, National Association (successor to U.S. Bank National Association), as Trustee (including the form of the 5.625% Senior Notes due 2034).

Exhibit 4.2 Execution Version EIGHTH SUPPLEMENTAL INDENTURE by and among Ventas Realty, Limited Partnership, as Issuer, Ventas, Inc., as Guarantor and U.S. Bank Trust Company, National Association, as Trustee $500,000,000 5.625% Senior Notes due 2034 Dated as of May 13, 2024 Supplement to Indenture dated as of February 23, 2018 (Senior Debt Securities) TABLE OF CONTENTS Page ARTICLE I CREATION OF

Underwriting Agreement, dated May 8, 2024, among Ventas Realty, Limited Partnership, Ventas, Inc. and the Underwriters named therein, relating to the 5.625% Senior Notes due 2034.

Exhibit 1.1 Execution Version VENTAS REALTY, LIMITED PARTNERSHIP $500,000,000 5.625% Senior Notes due 2034 UNDERWRITING AGREEMENT Dated May 8, 2024 J.P. Morgan Securities LLC Wells Fargo Securities, LLC BofA Securities, Inc. UNDERWRITING AGREEMENT May 8, 2024 J.P. Morgan Securities LLC 383 Madison Avenue New York, New York 10179 Wells Fargo Securities, LLC 550 South Tryon Street Charlotte, North C

Calculation of Filing Fee Tables (Form Type) Ventas, Inc. Ventas Realty, Limited Partnership (Exact Name of Registrants as Specified in its Charter) Table 1: Newly Registered and Carry Forward Securities

Exhibit 107 Calculation of Filing Fee Tables 424(b)(2) (Form Type) Ventas, Inc. and Ventas Realty, Limited Partnership (Exact Name of Registrants as Specified in its Charter) Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee R

Ventas Realty, Limited Partnership $500,000,000 5.625% Senior Notes due 2034 Fully and unconditionally guaranteed by Ventas, Inc.

TABLE OF CONTENTS  Filed Pursuant to Rule 424(b)(2)  Registration Statement Nos. 333-277185 and 333-277185-01 PROSPECTUS SUPPLEMENT (To prospectus dated February 20, 2024) Ventas Realty, Limited Partnership $500,000,000 5.625% Senior Notes due 2034 Fully and unconditionally guaranteed by Ventas, Inc. Ventas Realty, Limited Partnership (the “issuer”) is offering $500.0 million aggregate principal a

Subject to Completion Preliminary Prospectus Supplement dated May 8, 2024

TABLE OF CONTENTS The information in this preliminary prospectus supplement is not complete and may be changed.

PRICING TERM SHEET VENTAS REALTY, LIMITED PARTNERSHIP Fully and unconditionally guaranteed by Ventas, Inc. Terms applicable to $500,000,000 5.625% Senior Notes due 2034 Dated: May 8, 2024

Issuer Free Writing Prospectus Filed pursuant to Rule 433 Supplementing the Preliminary Prospectus Supplement dated May 8, 2024 and the Prospectus dated February 20, 2024 Registration Nos.

List of Guarantors and Issuers of Guaranteed Securities

Exhibit 22 List of Guarantors and Issuers of Guaranteed Securities As of March 31, 2024, Ventas, Inc.

Exhibit 4.1 TENTH SUPPLEMENTAL INDENTURE by and among Ventas Canada Finance Limited, as Issuer Ventas, Inc., as Guarantor and Computershare Trust Company of Canada, as Trustee Cdn$650,000,000 5.10% Senior Notes, Series J due 2029 ___________________

vtr-ex41033124tenthsupp Exhibit 4.1 TENTH SUPPLEMENTAL INDENTURE by and among Ventas Canada Finance Limited, as Issuer Ventas, Inc., as Guarantor and Computershare Trust Company of Canada, as Trustee Cdn$650,000,000 5.10% Senior Notes, Series J due 2029 Dated as of March 5, 2024 Supplement to Indenture dated as of September 24, 2014 (Senior Debt Securities) LEGAL1:84937475.6 TABLE OF CONTENTS Page

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROMTO Commission file number: 1-10989 Ventas, Inc.

Ventas Reports 2024 First Quarter Results

Exhibit 99.1 Ventas, Inc. 353 North Clark Street, Suite 3300 Chicago, Illinois 60654 (877) 4-VENTAS www.ventasreit.com Contact: BJ Grant (877) 4-VENTAS Ventas Reports 2024 First Quarter Results CHICAGO – (BUSINESS WIRE) – Ventas, Inc. (NYSE: VTR) (“Ventas” or the “Company”) today reported results for the first quarter ended March 31, 2024. CEO Remarks “2024 is off to a strong start, led by continu

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 1, 2024 Ventas, Inc. (Exact name of registrant as specified in its charter) Delaware 1-10989 61-1055020 (State or other jurisdiction of incorporation) (Commission File Number) (IR

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): April 24, 2024 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 1-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Number)

Fourth Amended and Restated Credit and Guaranty Agreement, dated as of April 24, 2024, among Ventas Realty, Limited Partnership, Ventas SSL Ontario II, Inc., Ventas Canada Finance Limited, Ventas UK Finance, Inc., and Ventas Euro Finance, LLC, as Borrowers, Ventas, Inc., as Guarantor, the Lenders identified therein, Bank of America, N.A., as Administrative Agent, and Bank of America, N.A., JPMorgan Chase Bank, N.A. and Wells Fargo Bank, National Association, as L/C Issuers.

Exhibit 10.1 EXECUTION COPY Published Deal CUSIP Number: 92276LBP1 Published Revolver Facility (Dollar Tranche Loans) CUSIP Number: 92276LBQ9 Published Revolver Facility (Alternative Currency Tranche Loans) CUSIP Number: 92276LBR7 Published Revolver Facility (Multicurrency Revolving Tranche Loans) CUSIP Number: 92276LBS5 FOURTH AMENDED AND RESTATED CREDIT AND GUARANTY AGREEMENT Dated as of April 2

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) þ Filed by the Registrant o Filed by a party other than the Registrant CHECK THE APPROPRIATE BOX: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Defin

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) þ Filed by the Registrant o Filed by a party other than the Registrant CHECK THE APPROPRIATE BOX: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 4, 2024 Ventas, Inc. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 4, 2024 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 1-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Number) (

Ventas Announces James D. Shelton Has Decided to Retire from Board Before 2024 Annual Meeting Roxanne M. Martino Appointed to Serve as Lead Independent Director Following 2024 Annual Meeting

Exhibit 99.1 Ventas Announces James D. Shelton Has Decided to Retire from Board Before 2024 Annual Meeting Roxanne M. Martino Appointed to Serve as Lead Independent Director Following 2024 Annual Meeting CHICAGO – MARCH 4, 2024 – Ventas, Inc. (NYSE: VTR) today announced that James D. (“Denny”) Shelton , the Lead Independent Director of the Ventas Board of Directors, has decided to retire from the

Regulation FD Disclosure, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 4, 2024 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 1-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Number) (

Cooperation Agreement, dated March 4, 2024

Exhibit 10.1 COOPERATION AGREEMENT This Cooperation Agreement (this “Agreement”) is made and entered into as of March 4, 2024 by and between VENTAS, INC., a Delaware corporation (the “Company”), on one hand, and LAND & BUILDINGS CAPITAL GROWTH FUND, LP, a Delaware limited partnership (“L&B Capital”), and its Affiliates, including but not limited to LAND & BUILDINGS INVESTMENT MANAGEMENT, LLC, a De

Ventas Appoints Theodore Bigman and Joe V. Rodriguez, Jr. to Board of Directors Enters Into Cooperation Agreement with Land & Buildings

Exhibit 99.1 Ventas Appoints Theodore Bigman and Joe V. Rodriguez, Jr. to Board of Directors Enters Into Cooperation Agreement with Land & Buildings CHICAGO – MARCH 4, 2024 – Ventas, Inc. (NYSE: VTR) today announced that its Board of Directors has appointed Theodore Bigman and Joe V. Rodriguez, Jr. to the Board, effective immediately. In connection with the appointments, which align with Ventas’s

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): February 29, 2024 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 1-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Numbe

Ventas Prices Cdn$650 Million of 5.10% Senior Notes Due 2029

Exhibit 99.1 Ventas Prices Cdn$650 Million of 5.10% Senior Notes Due 2029 CHICAGO-(BUSINESS WIRE)-Ventas, Inc. (NYSE: VTR) (“Ventas” or the “Company”) said today that it has priced a private offering in Canada of Cdn$650 million of 5.10% Senior Notes, Series J due 2029 (the “Notes”). The sale of the Notes is expected to close on March 5, 2024, subject to satisfaction of customary closing condition

Amendment No. 1 to the Sales Agreement, dated February 20, 2024, among Ventas, Inc. and the Agents and Forward Purchasers named therein.

Exhibit 1.1 Ventas, Inc. Common Stock ($0.25 par value) AMENDMENT NO. 1 TO ATM SALES AGREEMENT February 20, 2024 BofA Securities, Inc. BNP Paribas Securities Corp. Citigroup Global Markets Inc. Credit Agricole Securities (USA) Inc. Jefferies LLC J.P. Morgan Securities LLC Mizuho Securities USA LLC Morgan Stanley & Co. LLC MUFG Securities Americas Inc. RBC Capital Markets, LLC Scotia Capital (USA)

Entry into a Material Definitive Agreement, Other Events, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): February 20, 2024 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Num

Calculation of Filing Fee Tables (Form Type) Ventas, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered and Carry Forward Securities

Exhibit 107 Calculation of Filing Fee Tables 424(b)(5) (Form Type) Ventas, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee (1) Newly

As filed with the Securities and Exchange Commission on February 20, 2024

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on February 20, 2024 Registration No.

$1,000,000,000 Ventas, Inc. Common Stock

TABLE OF CONTENTS  Filed Pursuant to Rule 424(b)(5)   Registration Statement No. 333-277185 PROSPECTUS SUPPLEMENT (To prospectus dated February 20, 2024) $1,000,000,000 Ventas, Inc. Common Stock On February 20, 2024, we entered into Amendment No. 1 (the “Amendment”) to our ATM Sales Agreement, dated November 8, 2021 (as may be amended from time to time, the “Sales Agreement”), with BofA Securities

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Ventas, Inc. and Ventas Realty, Limited Partnership (Exact Name of Registrants as Specified in its Charter) Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule (1) Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fe

Statement of Eligibility of Trustee on Form T-1 under the Trust Indenture Act of 1939, as amended, of the trustee under the Subordinated Indenture referenced in Exhibit 4.6.

Exhibit 25.2 securities and exchange commission Washington, D.C. 20549 FORM T-1 Statement of Eligibility Under The Trust Indenture Act of 1939 of a Corporation Designated to Act as Trustee Check if an Application to Determine Eligibility of a Trustee Pursuant to Section 305(b)(2) ¨ U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION (Exact name of Trustee as specified in its charter) 91-1821036 I.R.S. E

Statement of Eligibility of Trustee on Form T-1 under the Trust Indenture Act of 1939, as amended, of the trustee under the Indenture referenced in Exhibit 4.5.

Exhibit 25.1 securities and exchange commission Washington, D.C. 20549 FORM T-1 Statement of Eligibility Under The Trust Indenture Act of 1939 of a Corporation Designated to Act as Trustee Check if an Application to Determine Eligibility of a Trustee Pursuant to Section 305(b)(2) ¨ U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION (Exact name of Trustee as specified in its charter) 91-1821036 I.R.S. E

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the year ended December 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission file number: 1-10989 Ventas, Inc. (Exact Nam

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): February 14, 2024 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Num

SUBSIDIARIES OF VENTAS, INC.

Exhibit 21 SUBSIDIARIES OF VENTAS, INC. Entity Name Jurisdiction of Organization or Formation 1425 Hunt Club, LLC Delaware 1445 Hunt Club, LLC Delaware 14851 Yorba Street, LLC Delaware 200 Andrews, LLC South Carolina 2010 Union Limited Partnership Washington 311 South Sarah, LLC Delaware 3737 Market Investment Fund, LLC Missouri 4210 Duncan, LLC Delaware 4220 Duncan Holding, LLC Delaware 4220 Dunc

VENTAS INC. AMENDED AND RESTATED POLICY FOR RECOUPMENT OF INCENTIVE COMPENSATION

AS APPROVED AND ADOPTED OCTOBER 12, 2023 VENTAS INC. AMENDED AND RESTATED POLICY FOR RECOUPMENT OF INCENTIVE COMPENSATION This Amended and Restated Policy for Recoupment of Incentive Compensation (“Policy”) has been adopted by the Compensation Committee of the Board of Directors (the “Board”) of Ventas Inc. (the “Company”) on October 12, 2023 with effect on December 1, 2023. This Policy provides f

Ventas Reports 2023 Full Year Results and Provides 2024 Outlook

Exhibit 99.1 Ventas Reports 2023 Full Year Results and Provides 2024 Outlook CHICAGO-(BUSINESS WIRE)-February 14, 2024-Ventas, Inc. (NYSE: VTR) (“Ventas” or the “Company”) today reported results for the full year and fourth quarter ended December 31, 2023. CEO Remarks “Ventas delivered strong growth in the fourth quarter and full year 2023, fueled by property performance. We are pleased to have ac

List of Guarantors and Issuers of Guaranteed Securities (incorporated herein by reference to Exhibit 22 to Ventas, Inc’s Annual Report on Form 10-K for the year ended December 31, 2023).

Exhibit 22 List of Guarantors and Issuers of Guaranteed Securities As of December 31, 2023, Ventas, Inc.

Exhibit 4.28

Exhibit 4.28 DESCRIPTION OF THE REGISTRANT’S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 The summary set forth below describes the general terms and provisions of the common stock of Ventas, Inc. The following description is only a summary and does not purport to be complete and is subject to and qualified in its entirety by reference to the Amended and Rest

VTR / Ventas, Inc. / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 19)* Name of issuer: Ventas Inc Title of Class of Securities: Common Stock CUSIP Number: 92276F100 Date of Event Which Requires Filing of this Statement: December 29, 2023 Check the appropriate box to designate the rule pursuant to which this Schedule is filed: ☒ Rule 13

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Defin

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Defin

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Ame

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☐ Filed by a Party other than the Registrant ☒ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confide

VTR / Ventas, Inc. / JPMORGAN CHASE & CO - FILING VENTAS, INC. Passive Investment

Schedule 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 01)* Ventas, Inc. (Name of Issuer) Common Stock, $0.25 par value (Title of Class of Securities) 92276F100 (CUSIP Number) December 29, 2023 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pu

List of Guarantors and Issuers of Guaranteed Securities

Exhibit 22 List of Guarantors and Issuers of Guaranteed Securities As of September 30, 2023, Ventas, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROMTO Commission file number: 1-10989 Ventas,

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): November 2, 2023 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Numb

Ventas Reports 2023 Third Quarter Results

Exhibit 99.1 Ventas Reports 2023 Third Quarter Results CHICAGO-(BUSINESS WIRE)-November 2, 2023-Ventas, Inc. (NYSE: VTR) (“Ventas” or the “Company”) today reported results for the third quarter ended September 30, 2023. CEO Remarks “Ventas delivered a strong third quarter, reflecting attractive property growth across all business segments,” said Debra A. Cafaro, Ventas Chairman and CEO. “Consisten

Credit and Guaranty Agreement, dated as of September 6, 2023, among Ventas Realty, Limited Partnership, a Delaware limited partnership, as borrower, Ventas, Inc., a Delaware corporation, as guarantor, the lending institutions party thereto from time to time, and Bank of America, N.A., as Administrative Agent.

Exhibit 10.1 EXECUTION COPY Published Deal CUSIP Number: 92276LBM8 Published Term CUSIP: 92276LBN6 CREDIT AND GUARANTY AGREEMENT Dated as of September 6, 2023 among VENTAS REALTY, LIMITED PARTNERSHIP, as Borrower, VENTAS, INC., as Guarantor, THE LENDERS PARTY HERETO FROM TIME TO TIME, BANK OF AMERICA, N.A., as Administrative Agent, BofA SECURITIES, INC., JPMORGAN CHASE BANK, N.A. and MORGAN STANLE

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): September 6, 2023 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Num

List of Guarantors and Issuers of Guaranteed Securities

Exhibit 22 List of Guarantors and Issuers of Guaranteed Securities As of June 30, 2023, Ventas, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROMTO Commission file number: 1-10989 Ventas, Inc.

SECOND AMENDMENT

EXECUTION COPY SECOND AMENDMENT This SECOND AMENDMENT, dated as of June 26, 2023 (this “Amendment”), to that certain Third Amended and Restated Credit and Guaranty Agreement referenced below, is by and among VENTAS REALTY, LIMITED PARTNERSHIP, a Delaware limited partnership (the “Parent Borrower”), VENTAS SSL ONTARIO II, INC.

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): August 3, 2023 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Number

Ventas Reports 2023 Second Quarter Results

Exhibit 99.1 Ventas Reports 2023 Second Quarter Results CHICAGO-(BUSINESS WIRE)-August 3, 2023-Ventas, Inc. (NYSE: VTR) (“Ventas” or the “Company”) today reported results for the second quarter ended June 30, 2023. CEO Remarks “We are pleased to deliver strong second quarter results with broad-based organic property growth across our diverse portfolio,” said Debra A. Cafaro, Ventas Chairman and CE

Indenture, dated June 13, 2023, among the Issuer, the Guarantor and U.S. Bank Trust Company, National Association

Exhibit 4.1 Execution Version VENTAS REALTY, LIMITED PARTNERSHIP, as Issuer, VENTAS, INC., as Guarantor, AND U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, as Trustee INDENTURE Dated as of June 13, 2023 3.75% Exchangeable Senior Notes due 2026 TABLE OF CONTENTS Page Article 1 Definitions 1 Section 1.01. Definitions 1 Section 1.02. References to Interest 15 Article 2 Issue, Description, Execution,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): June 8, 2023 Ventas, Inc. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): June 8, 2023 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 1-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Number) (I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): June 8, 2023 Ventas, Inc. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): June 8, 2023 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 1-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Number) (I

Ventas Realty, Limited Partnership Announces Upsize and Pricing of $750 Million of Exchangeable Senior Notes

Exhibit 99.2 News Release Ventas Realty, Limited Partnership Announces Upsize and Pricing of $750 Million of Exchangeable Senior Notes CHICAGO—(BUSINESS WIRE)—June 8, 2023—Ventas Realty, Limited Partnership (“Ventas Realty”), a wholly-owned subsidiary of Ventas, Inc. (“Ventas”) (NYSE: VTR), announced today the pricing of $750 million aggregate principal amount of its 3.75% Exchangeable Senior Note

Ventas Realty, Limited Partnership Announces Proposed Private Placement of $500 Million of Exchangeable Senior Notes

Exhibit 99.1 News Release Ventas Realty, Limited Partnership Announces Proposed Private Placement of $500 Million of Exchangeable Senior Notes CHICAGO—(BUSINESS WIRE)—June 8, 2023—Ventas Realty, Limited Partnership (“Ventas Realty”), a wholly-owned subsidiary of Ventas, Inc. (“Ventas”) (NYSE: VTR), announced today that it intends to offer, subject to market conditions and other factors, $500 milli

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 16, 2023 Ventas, Inc. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 16, 2023 Ventas, Inc. (Exact name of registrant as specified in its charter) Delaware 001-10989 61-1055020 (State or other jurisdiction of incorporation) (Commission File Number)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROMTO Commission file number: 1-10989 Ventas, Inc.

NINTH SUPPLEMENTAL INDENTURE by and among Ventas Canada Finance Limited, as Issuer Ventas, Inc., as Guarantor Computershare Trust Company of Canada, as Trustee 5.398% Senior Notes, Series I due 2028 ___________________ Dated as of April 21, 2023 Supp

NINTH SUPPLEMENTAL INDENTURE by and among Ventas Canada Finance Limited, as Issuer Ventas, Inc.

List of Guarantors and Issuers of Guaranteed Securities

Exhibit 22 List of Guarantors and Issuers of Guaranteed Securities As of March 31, 2023, Ventas, Inc.

UNITED STATES

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 8, 2023 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Number) (

Ventas Reports 2023 First Quarter Results

Exhibit 99.1 Ventas Reports 2023 First Quarter Results CHICAGO-(BUSINESS WIRE)-May 8, 2023-Ventas, Inc. (NYSE: VTR) (“Ventas” or the “Company”) today reported results for the first quarter ended March 31, 2023. CEO Remarks “Ventas’s excellent first quarter results underscore the strong momentum across our diverse business. Our performance was led by outstanding top- and bottom-line growth in SHOP,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) ☑ Filed by the Registrant ☐ Filed by a party other than the Registrant CHECK THE APPROPRIATE BOX: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defin

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) ☑ Filed by the Registrant ☐ Filed by a party other than the Registrant CHECK THE APPROPRIATE BOX: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14

DEFINITIVE PROXY STATEMENT

2023 Proxy Statement for Annual Meeting of StockholdersLetter to Ventas Stockholders Dear Fellow Stockholder, On behalf of our Board of Directors, I am pleased to present the 2023 Ventas Proxy Statement and invite you to join our Annual Meeting of Stockholders on May 16, 2023.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): April 3, 2023 Ventas, Inc. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): April 3, 2023 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 1-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Number) (

Ventas Launches Offering of Cdn$500 Million of Senior Notes Due 2028

Exhibit 99.1 Ventas Launches Offering of Cdn$500 Million of Senior Notes Due 2028 CHICAGO-(BUSINESS WIRE)-Ventas, Inc. (NYSE: VTR) (“Ventas” or the “Company”) said today that it has launched a private offering in Canada of Cdn$500 million of Senior Notes, Series I due 2028 (the “Notes”). Final terms of the Notes, including aggregate principal amount, interest rate and certain other terms, will be

Ventas Prices Cdn$600 Million of 5.398% Senior Notes Due 2028

Exhibit 99.2 Ventas Prices Cdn$600 Million of 5.398% Senior Notes Due 2028 CHICAGO-(BUSINESS WIRE)-Ventas, Inc. (NYSE: VTR) (“Ventas” or the “Company”) said today that it has priced a private offering in Canada of Cdn$600 million of 5.398% Senior Notes, Series I due 2028 (the “Notes”). The sale of the Notes is expected to close on April 21, 2023, subject to satisfaction of customary closing condit

VENTAS, INC. 2022 INCENTIVE PLAN NOTICE OF RESTRICTED STOCK UNIT AWARD Subject to the terms and conditions of the Ventas, Inc. 2022 Incentive Plan (the “Plan”), this Notice of Restricted Stock Unit Award (the “Notice”) and the Terms and Conditions pr

VENTAS, INC. 2022 INCENTIVE PLAN NOTICE OF RESTRICTED STOCK UNIT AWARD Subject to the terms and conditions of the Ventas, Inc. 2022 Incentive Plan (the “Plan”), this Notice of Restricted Stock Unit Award (the “Notice”) and the Terms and Conditions provided herewith (the “Terms and Conditions” and, collectively with the Notice, the “Award Agreement”), as of the grant date specified below (the “Gran

1 VENTAS, INC. RESTRICTED STOCK AGREEMENT THIS RESTRICTED STOCK AGREEMENT (“Agreement”) is made and entered into as of the October 1, 2022 (the “Grant Date”), by and between VENTAS, INC., a Delaware corporation (the “Company”), and Sumit Roy, a non-e

1 VENTAS, INC. RESTRICTED STOCK AGREEMENT THIS RESTRICTED STOCK AGREEMENT (“Agreement”) is made and entered into as of the October 1, 2022 (the “Grant Date”), by and between VENTAS, INC., a Delaware corporation (the “Company”), and Sumit Roy, a non-employee director of the Company (“Director”), pursuant to the Ventas, Inc. 2022 Incentive Plan (the “Plan”). AGREEMENT: The parties agree as follows:

List of Guarantors and Issuers of Guaranteed Securities

Exhibit 22 List of Guarantors and Issuers of Guaranteed Securities As of December 31, 2022, Ventas, Inc.

EXECUTION VERSION SEPARATION AND TRANSITION AGREEMENT This Separation and Transition Agreement (the “Agreement”), dated as of January 21, 2023, is entered into between Ventas, Inc. (together with its subsidiaries and affiliates, the “Company”) and Jo

EXECUTION VERSION SEPARATION AND TRANSITION AGREEMENT This Separation and Transition Agreement (the “Agreement”), dated as of January 21, 2023, is entered into between Ventas, Inc.

1 VENTAS, INC. RESTRICTED STOCK UNIT AGREEMENT THIS RESTRICTED STOCK UNIT AGREEMENT (“Agreement”) is made and entered into effective as of [DATE] (the “Grant Date”), by and between VENTAS, INC., a Delaware corporation (the “Company”), and [DIRECTOR N

1 VENTAS, INC. RESTRICTED STOCK UNIT AGREEMENT THIS RESTRICTED STOCK UNIT AGREEMENT (“Agreement”) is made and entered into effective as of [DATE] (the “Grant Date”), by and between VENTAS, INC., a Delaware corporation (the “Company”), and [DIRECTOR NAME], a non-employee director of the Company (“Director”), pursuant to the Ventas, Inc. 2022 Incentive Plan (the “Plan”). AGREEMENT: The parties agree

1 #96297977v8 VENTAS, INC. PERFORMANCE SHARE UNIT AGREEMENT THIS PERFORMANCE SHARE UNIT AGREEMENT (“Agreement”) is made and entered into as of the _____ day of __________, _____ (the “Grant Date”), by and between VENTAS, INC., a Delaware corporation

1 #96297977v8 VENTAS, INC. PERFORMANCE SHARE UNIT AGREEMENT THIS PERFORMANCE SHARE UNIT AGREEMENT (“Agreement”) is made and entered into as of the day of , (the “Grant Date”), by and between VENTAS, INC., a Delaware corporation (the “Company”), and Debra A. Cafaro, an employee of the Company (“Employee”), pursuant to the Ventas, Inc. 2022 Incentive Plan (the “Plan”). AGREEMENT: The parties agree a

VENTAS, INC. NON-EMPLOYEE DIRECTORS’ EQUITY AWARD DEFERRAL PROGRAM (adopted pursuant to the Ventas, Inc. 2022 Incentive Plan) ELECTION AGREEMENT I. DEFERRAL AND PAYMENT ELECTIONS FOR RESTRICTED STOCK UNITS To the extent that I receive an award of Res

VENTAS, INC. NON-EMPLOYEE DIRECTORS’ EQUITY AWARD DEFERRAL PROGRAM (adopted pursuant to the Ventas, Inc. 2022 Incentive Plan) ELECTION AGREEMENT I. DEFERRAL AND PAYMENT ELECTIONS FOR RESTRICTED STOCK UNITS To the extent that I receive an award of Restricted Stock Units pursuant to the Ventas, Inc. 2022 Incentive Plan or any successor plan (collectively, the “Plan”), I hereby make the following ele

1 VENTAS, INC. NON-EMPLOYEE DIRECTORS’ CASH COMPENSATION DEFERRAL PLAN As amended December 7, 2022 ARTICLE 1 INTRODUCTION 1.1 Establishment. Ventas, Inc. (the “Company”) hereby establishes the Ventas Non-Employee Directors’ Cash Compensation Deferral

1 VENTAS, INC. NON-EMPLOYEE DIRECTORS’ CASH COMPENSATION DEFERRAL PLAN As amended December 7, 2022 ARTICLE 1 INTRODUCTION 1.1 Establishment. Ventas, Inc. (the “Company”) hereby establishes the Ventas Non-Employee Directors’ Cash Compensation Deferral Plan (the “Plan”) for those directors of the Company who are not employees of the Company or any of its subsidiaries or affiliates. The Plan allows N

1 VENTAS, INC. 2022 INCENTIVE PLAN NOTICE OF PERFORMANCE SHARE UNIT AWARD Subject to the terms and conditions of the Ventas, Inc. 2022 Incentive Plan (the “Plan”), this Notice of Performance Share Unit Award (the “Notice”) and the Terms and Condition

1 VENTAS, INC. 2022 INCENTIVE PLAN NOTICE OF PERFORMANCE SHARE UNIT AWARD Subject to the terms and conditions of the Ventas, Inc. 2022 Incentive Plan (the “Plan”), this Notice of Performance Share Unit Award (the “Notice”) and the Terms and Conditions provided herewith (the “Terms and Conditions” and, collectively with the Notice, the “Award Agreement”), as of the grant date specified below (the “

SUBSIDIARIES OF VENTAS, INC.

Exhibit 21 SUBSIDIARIES OF VENTAS, INC. Entity Name Jurisdiction of Organization or Formation 1425 Hunt Club, LLC Delaware 1445 Hunt Club, LLC Delaware 14851 Yorba Street, LLC Delaware 200 Andrews, LLC South Carolina 2010 Union Limited Partnership Washington 311 South Sarah, LLC Delaware 3737 Market Investment Fund, LLC Missouri 4210 Duncan, LLC Delaware 4220 Duncan Holding, LLC Delaware 4220 Dunc

NON-EMPLOYEE DIRECTORS’ CASH COMPENSATION DEFERRAL PLAN DIRECTOR FEE AND DIVIDEND DEFERRAL ELECTION FORM I. ELECTION TO DEFER DIRECTOR FEES Pursuant to the Ventas Non-Employee Directors’ Cash Compensation Deferral Plan (formerly known as the “Nonempl

NON-EMPLOYEE DIRECTORS’ CASH COMPENSATION DEFERRAL PLAN DIRECTOR FEE AND DIVIDEND DEFERRAL ELECTION FORM I.

DESCRIPTION OF THE REGISTRANT’S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934

Exhibit 4.27 DESCRIPTION OF THE REGISTRANT’S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 The summary set forth below describes the general terms and provisions of Ventas, Inc.’s common stock. The following description is only a summary and does not purport to be complete and is subject to and qualified in its entirety by reference to Ventas, Inc.’s Certifica

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the year ended December 31, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission file number: 1-10989 Ventas, Inc. (Exact Nam

1 Non-Employee Directors’ Equity Award Deferral Program VENTAS, INC. NON-EMPLOYEE DIRECTORS’ EQUITY AWARD DEFERRAL PROGRAM adopted pursuant to the Ventas, Inc. 2022 Incentive Plan December 7, 2022 ARTICLE 1 INTRODUCTION 1.1 Establishment. Ventas, Inc

1 Non-Employee Directors’ Equity Award Deferral Program VENTAS, INC. NON-EMPLOYEE DIRECTORS’ EQUITY AWARD DEFERRAL PROGRAM adopted pursuant to the Ventas, Inc. 2022 Incentive Plan December 7, 2022 ARTICLE 1 INTRODUCTION 1.1 Establishment. Ventas, Inc. (the “Company”) hereby establishes the Ventas, Inc. Non-Employee Directors’ Equity Award Deferral Program (the “Program”) for those directors of the

RSU Agreement January 2023—Cafaro #96297982v5 VENTAS, INC. RESTRICTED STOCK UNIT AGREEMENT THIS RESTRICTED STOCK UNIT AGREEMENT (“Agreement”) is made and entered into effective as of the ___ day of __________________, ______ (the “Grant Date”), by an

RSU Agreement January 2023—Cafaro #96297982v5 VENTAS, INC. RESTRICTED STOCK UNIT AGREEMENT THIS RESTRICTED STOCK UNIT AGREEMENT (“Agreement”) is made and entered into effective as of the day of , (the “Grant Date”), by and between VENTAS, INC., a Delaware corporation (the “Company”), and Debra A. Cafaro, an employee of the Company (“Employee”), pursuant to the Ventas, Inc. 2022 Incentive Plan (the

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): February 9, 2023 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Numb

Ventas Reports 2022 Fourth Quarter and Full Year Results and Provides 2023 Outlook

Exhibit 99.1 Ventas Reports 2022 Fourth Quarter and Full Year Results and Provides 2023 Outlook CHICAGO-(BUSINESS WIRE)-February 9, 2023-Ventas, Inc. (NYSE: VTR) (“Ventas” or the “Company”) today reported results for the fourth quarter and full year ended December 31, 2022. CEO Remarks “We are pleased to have delivered a strong fourth quarter, which reflects the attractive operating and financial

VTR / Ventas, Inc. / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SC 13G/A 1 tv02169-ventasinc.htm SCHEDULE 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 18)* Name of issuer: Ventas Inc. Title of Class of Securities: REIT CUSIP Number: 92276F100 Date of Event Which Requires Filing of this Statement: December 30, 2022 Check the appropriate box to designate the rule pursuant t

Ventas Appoints J. Justin Hutchens, Executive Vice President, Senior Housing, to Additional Role of Chief Investment Officer

Exhibit 99.1 Ventas, Inc. 353 North Clark Street, Suite 3300 Chicago, Illinois 60654 (877) 4-VENTAS www.ventasreit.com Ventas Appoints J. Justin Hutchens, Executive Vice President, Senior Housing, to Additional Role of Chief Investment Officer CHICAGO – January 23, 2023 – Ventas, Inc. (NYSE: VTR) (“Ventas” or the “Company”) today announced that J. Justin Hutchens, Executive Vice President, Senior

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Other Events, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): January 21, 2023 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Numb

VTR / Ventas, Inc. / JPMORGAN CHASE & CO - FILING VENTAS, INC. Passive Investment

Schedule 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Ventas, Inc. (Name of Issuer) Common Stock, $0.25 par value (Title of Class of Securities) 92276F100 (CUSIP Number) December 30, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule purs

List of Guarantors and Issuers of Guaranteed Securities

Exhibit 22 List of Guarantors and Issuers of Guaranteed Securities As of September 30, 2022, Ventas, Inc.

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): November 3, 2022 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Numb

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROMTO Commission file number: 1-10989 Ventas,

Ventas Reports 2022 Third Quarter Results

Exhibit 99.1 Ventas Reports 2022 Third Quarter Results CHICAGO-(BUSINESS WIRE)-November 3, 2022-Ventas, Inc. (NYSE: VTR) (?Ventas? or the ?Company?) today reported results for the third quarter ended September 30, 2022. Third Quarter 2022 Highlights Net Income Attributable to Common Stockholders (?Attributable Net Income (Loss)?) per share of $0.00 Normalized Funds from Operations* (?Normalized FF

As filed with the Securities and Exchange Commission on September 19, 2022

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on September 19, 2022? Registration No.

As filed with the Securities and Exchange Commission on September 19, 2022

As filed with the Securities and Exchange Commission on September 19, 2022 Registration No.

Filing Fee Table

Exhibit 107.1 CALCULATION OF FILING FEE Form S-8 (Form type) Ventas, Inc. (Exact Name of Registrant as Specified in its Charter) Table I: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Common Stock, par value $0.25 per share

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Ventas, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Newly Registered Securities

Ventas Appoints Sumit Roy, CEO of Realty Income, to Board of Directors Robert Reed to Retire from the Board at 2023 Annual Meeting

Exhibit 99.1 FOR IMMEDIATE RELEASE Ventas Appoints Sumit Roy, CEO of Realty Income, to Board of Directors Robert Reed to Retire from the Board at 2023 Annual Meeting CHICAGO ? September 12, 2022 ? Ventas, Inc. (NYSE: VTR) today announced that Sumit Roy, President and Chief Executive Officer of Realty Income Corporation ? a real estate investment trust (REIT) with a diversified portfolio of over 11

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): September 12, 2022 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Nu

List of Guarantors and Issuers of Guaranteed Securities

Exhibit 22 List of Guarantors and Issuers of Guaranteed Securities As of June 30, 2022, Ventas, Inc.

Incorporated by reference herein. Previously filed as Exhibit 10.1 to our Quarterly Report on Form 10-Q for the quarter ended June 30, 2022. File No. 001-10989.

VENTAS, INC. 2022 INCENTIVE PLAN I. Purpose The purpose of the Ventas, Inc. 2022 Incentive Plan (?Plan?) is to promote the growth and profitability of Ventas, Inc., a Delaware corporation (?Company?), and its subsidiaries and to increase stockholder value by providing officers, key employees, key consultants and non-employee directors with incentives to achieve long-term objectives of the Company.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROMTO Commission file number: 1-10989 Ventas, Inc.

Ventas Reports 2022 Second Quarter Results

Exhibit 99.1 Ventas Reports 2022 Second Quarter Results CHICAGO-(BUSINESS WIRE)-August 4, 2022-Ventas, Inc. (NYSE: VTR) (?Ventas? or the ?Company?) today reported results for the second quarter ended June 30, 2022. Second Quarter 2022 Highlights Net Income (Loss) Attributable to Common Stockholders (?Attributable Net Income (Loss)?) per share of ($0.11) Normalized Funds from Operations* (?Normaliz

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): August 4, 2022 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Number

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): June 27, 2022 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Number)

Credit and Guaranty Agreement, dated as of June 27, 2022, among Ventas Realty, Limited Partnership, a Delaware limited partnership, as borrower, Ventas, Inc., a Delaware corporation, as guarantor, the lending institutions party thereto from time to time, and Bank of America, N.A., as Administrative Agent.

Exhibit 10.1 Execution Copy Published Deal CUSIP Number: 92276LBK2 Published Term CUSIP: 92276LBL0 CREDIT AND GUARANTY AGREEMENT Dated as of June 27, 2022 among VENTAS REALTY, LIMITED PARTNERSHIP, as Borrower, VENTAS, INC., as Guarantor, THE LENDERS PARTY HERETO FROM TIME TO TIME, BANK OF AMERICA, N.A., as Administrative Agent, BofA SECURITIES, INC., and JPMORGAN CHASE BANK, N.A., as Joint Bookrun

Sixth Amended and Restated Bylaws of Ventas, Inc. (incorporated herein by reference to Exhibit 3.1 to our Current Report on Form 8-K filed with the SEC on June 1, 2022).

Exhibit 3.1 SIXTH AMENDED AND RESTATED BY-LAWS OF VENTAS, INC. (as amended as of May 25, 2022) Article I OFFICES 1.1???????????REGISTERED OFFICE. The registered office of the Corporation shall be in the City of Wilmington, County of New Castle, State of Delaware. 1.2???????????OTHER OFFICES. The Corporation may also have offices at such other places both within and without the State of Delaware as

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Other Events, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 25, 2022 Ventas, Inc. (Exact name of registrant as specified in its charter) Delaware 001-10989 61-1055020 (State or other jurisdiction of incorporation) (Commission File Number)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROMTO Commission file number: 1-10989 Ventas, Inc.

List of Guarantors and Issuers of Guaranteed Securities

Exhibit 22 List of Guarantors and Issuers of Guaranteed Securities As of March 31, 2022, Ventas, Inc.

Ventas Reports 2022 First Quarter Results

Exhibit 99.1 Ventas Reports 2022 First Quarter Results CHICAGO-(BUSINESS WIRE)-May 5, 2022-Ventas, Inc. (NYSE: VTR) (?Ventas? or the ?Company?) today reported results for the first quarter ended March 31, 2022. Highlights Net Income Attributable to Common Stockholders (?Net Income?) per share of $0.10 Normalized Funds from Operations* (?Normalized FFO?) per share of $0.79, inclusive of the benefit

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 5, 2022 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Number) (

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 27, 2022 Ventas, Inc. (Exact name of registrant as specified in its charter) Delaware 001-10989 61-1055020 (State or other jurisdiction of incorporation) (Commission File Number

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Definitive Proxy State

EX-1

EX-1 2 ex1dfan14a10432041042122.htm Exhibit 1 Speaker 1: Recording in progress. Jonathan Litt, Founder and CIO: Good morning and thank you for joining Land and Buildings' webinar on Ventas. We've titled this presentation Curing a Decade of Underperformance at Ventas. If you'd like a copy of the presentation, you can go to the website cureventas.com. My name is Jon Litt. I'm the CIO of Land and Bui

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Ame

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confide

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Ame

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confide

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy State

INVESTOR SLIDE

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Ame

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confide

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Ame

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confide

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Definitive Proxy State

REBUTTAL INVESTOR PRESENTATION

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Ame

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confide

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Ame

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confide

EXHIBIT 1 - INVESTOR PRESENTATION

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Ame

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confide

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Ame

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confide

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.       )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.???????) Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by R

EXHIBIT 1

Definitive Proxy Statement on Schedule 14A relating to our 2022 Annual Meeting of Stockholders, filed with the SEC on March 29, 2022;

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Ame

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confide

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.       )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.???????) Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: x Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by R

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.   )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ??) Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Def

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.   )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ??) Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Def

Press Release, dated March 7, 2022

Exhibit 99.1 Ventas Appoints Michael J. Embler, Former Chief Investment Officer of Franklin Mutual Advisors, to Board of Directors Jay M. Gellert to Retire from the Board at 2022 Annual Meeting Melody Barnes to be Named Chair of the Board’s Nominating & Corporate Governance Committee Confirms Receipt of Nominations from Land & Buildings and Provides Update on Engagement CHICAGO – (BUSINESS WIRE) –

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Ame

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confide

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Ame

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confide

EXHIBIT 1 - SHAREHOLDER LETTER, DATED MARCH 7, 2022

Ventas Appoints Michael J. Embler, Former Chief Investment Officer of Franklin Mutual Advisors, to Board of Directors Jay M. Gellert to Retire from the Board at 2022 Annual Meeting Melody Barnes to be Named Chair of the Board’s Nominating & Corporate

Exhibit 99.1 Ventas Appoints Michael J. Embler, Former Chief Investment Officer of Franklin Mutual Advisors, to Board of Directors Jay M. Gellert to Retire from the Board at 2022 Annual Meeting Melody Barnes to be Named Chair of the Board?s Nominating & Corporate Governance Committee Confirms Receipt of Nominations from Land & Buildings and Provides Update on Engagement CHICAGO ? (BUSINESS WIRE) ?

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.   )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ??) Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Def

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Other Events, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 7, 2022 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Number)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 7, 2022 Ventas, Inc. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 7, 2022 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Number)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the year ended December 31, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission file number: 1-10989 Ventas, Inc. (Exact Nam

Exhibit 4.27

Exhibit 4.27 DESCRIPTION OF THE REGISTRANT?S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 The summary set forth below describes the general terms and provisions of Ventas, Inc.?s common stock. The following description is only a summary and does not purport to be complete and is subject to and qualified in its entirety by reference to Ventas, Inc.?s Certifica

SEVENTH SUPPLEMENTAL INDENTURE by and among Ventas Canada Finance Limited, as Issuer Ventas, Inc., as Guarantor Computershare Trust Company of Canada, as Trustee 2.45% Senior Notes, Series G due 2027 ___________________ Dated as of December 1, 2021 S

Exhibit 4.14 SEVENTH SUPPLEMENTAL INDENTURE by and among Ventas Canada Finance Limited, as Issuer Ventas, Inc., as Guarantor and Computershare Trust Company of Canada, as Trustee Cdn$475,000,000 2.45% Senior Notes, Series G due 2027 Dated as of December 1, 2021 Supplement to Indenture dated as of September 24, 2014 (Senior Debt Securities) LEGAL1:70779023.7 TABLE OF CONTENTS Page ARTICLE I CREATIO

SUBSIDIARIES OF VENTAS, INC.

Exhibit 21 SUBSIDIARIES OF VENTAS, INC. Entity Name Jurisdiction of Organization or Formation 1425 Hunt Club, LLC Delaware 1445 Hunt Club, LLC Delaware 14851 Yorba Street, LLC Delaware 200 Andrews, LLC South Carolina 2010 Union Limited Partnership Washington 311 South Sarah, LLC Delaware 3737 Market Investment Fund, LLC Missouri 4210 Duncan, LLC Delaware 4220 Duncan Holding, LLC Delaware 4220 Dunc

List of Guarantors and Issuers of Guaranteed Securities

Exhibit 22 List of Guarantors and Issuers of Guaranteed Securities As of December 31, 2021, Ventas, Inc.

EIGHTH SUPPLEMENTAL INDENTURE by and among Ventas Canada Finance Limited, as Issuer Ventas, Inc., as Guarantor Computershare Trust Company of Canada, as Trustee 3.30% Senior Notes, Series H due 2031 ___________________ Dated as of December 1, 2021 Su

Exhibit 4.15 EIGHTH SUPPLEMENTAL INDENTURE by and among Ventas Canada Finance Limited, as Issuer Ventas, Inc., as Guarantor and Computershare Trust Company of Canada, as Trustee Cdn$300,000,000 3.30% Senior Notes, Series H due 2031 Dated as of December 1, 2021 Supplement to Indenture dated as of September 24, 2014 (Senior Debt Securities) LEGAL1:70808890.5 TABLE OF CONTENTS Page ARTICLE I CREATION

Ventas Reports 2021 Fourth Quarter and Full Year Results

Exhibit 99.1 Ventas Reports 2021 Fourth Quarter and Full Year Results CHICAGO-(BUSINESS WIRE)-February 17, 2022-Ventas, Inc. (NYSE: VTR) (?Ventas? or the ?Company?) today reported results for the fourth quarter and full year ended December 31, 2021. ?We are proud of our company and team in 2021. With a relentless focus on execution, we drove the business forward amid continuing waves of COVID-19 a

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): February 17, 2022 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Num

VTR / Ventas, Inc. / COHEN & STEERS, INC. Passive Investment

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G* (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2 (Exit Filing)* Ventas Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 92276F100 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of th

VTR / Ventas, Inc. / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 17)* Name of issuer: Ventas Inc. Title of Class of Securities: REIT CUSIP Number: 92276F100 Date of Event Which Requires Filing of this Statement: December 31, 2021 Check the appropriate box to designate the rule pursuant to which this Schedule is filed: ☒ Rule 13d-1(b)

January 2022 Business Update January 20, 2022

Exhibit 99.1 January 2022 Business Update January 20, 2022 2 Cautionary Statements Certain of the information contained herein, including intra - quarter operating information and number of confirmed cases of COVI D - 19, has been provided by our operators and we have not verified this information through an independent investigation or otherwise. We have no reason to believe that this inf ormatio

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): January 20, 2022 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Numb

VTR / Ventas, Inc. / APG Asset Management US Inc. - SC 13G/A Passive Investment

SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2) Ventas, Inc. (Name of Issuer) Common Stock, $0.25 par value (Title of Class of Securities) 92276F100 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant

VTR / Ventas, Inc. / JPMORGAN CHASE & CO - FILING VENTAS, INC. Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 01)* Ventas, Inc. (Name of Issuer) Common Stock, $0.25 par value (Title of Class of Securities) 92276F100 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to whi

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): January 3, 2022 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Numbe

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933 ATTENTION: Transmit for filing 3 copies of this form concurrently with either

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933 ATTENTION: Transmit for filing 3 copies of this form concurrently with either placing an order with a broker to execute sale or executing a sale directly with a market maker. area code number OMB APPROVAL SEC USE ONLY DOCUMENT

ATM Sales Agreement, dated November 8, 2021, among the Company and BofA Securities, Inc., Citigroup Global Markets Inc., Credit Agricole Securities (USA) Inc., Jefferies LLC, J.P. Morgan Securities LLC, Mizuho Securities USA LLC, Morgan Stanley & Co. LLC, MUFG Securities Americas Inc., RBC Capital Markets, LLC, Scotia Capital (USA) Inc., SMBC Nikko Securities America, Inc., TD Securities (USA) LLC, UBS Securities LLC and Wells Fargo Securities, LLC, as sales agents and as forward sellers, and Bank of America, N.A., Citibank, N.A., Credit Agricole Corporate and Investment Bank, Jefferies LLC, JPMorgan Chase Bank, National Association, Mizuho Markets Americas LLC, Morgan Stanley & Co. LLC, MUFG Securities EMEA plc, RBC Capital Markets, LLC, The Bank of Nova Scotia, The Toronto-Dominion Bank, UBS AG London Branch and Wells Fargo Bank, National Association, as forward purchasers.

EX-1.1 2 tm2132029d2ex1-1.htm EXHIBIT 1.1 Exhibit 1.1 Execution Version Ventas, Inc. Common Stock ($0.25 par value) ATM SALES AGREEMENT November 8, 2021 BofA Securities, Inc. Citigroup Global Markets Inc. Credit Agricole Securities (USA) Inc. Jefferies LLC J.P. Morgan Securities LLC Mizuho Securities USA LLC Morgan Stanley & Co. LLC MUFG Securities Americas Inc. RBC Capital Markets, LLC Scotia Cap

Entry into a Material Definitive Agreement, Termination of a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): November 8, 2021 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Numb

CALCULATION OF REGISTRATION FEE

TABLE OF CONTENTS Filed Pursuant to Rule 424(b)(5) Registration Statement No. 333-253415? CALCULATION OF REGISTRATION FEE ? ? Title of Each Class of Securities to be Registered ? ? ? Proposed Maximum Aggregate Offering Price ? ? ? Amount of Registration Fee ? Common Stock, par value $0.25 per share ? ? ? ? $ 1,000,000,000 ? ? ? ? ? $ 92,700(1) ? ? ? (1) Calculated in accordance with Rules 456(b) a

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROMTO Commission file number: 1-10989 Ventas,

FIRST AMENDMENT (LIBOR TRANSITION)

Exhibit 10.1 FIRST AMENDMENT (LIBOR TRANSITION) This FIRST AMENDMENT (LIBOR TRANSITION) (this ?Agreement?), dated as of October 5, 2021 (the ?Amendment Effective Date?), is entered into among VENTAS REALTY, LIMITED PARTNERSHIP, a Delaware limited partnership (?Parent Borrower?), VENTAS SSL ONTARIO II, INC., an Ontario corporation (?Ventas SSL II?), VENTAS SSL ONTARIO III, INC., an Ontario corporat

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): November 5, 2021 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Numb

EX-22

Exhibit 22 List of Guarantors and Issuers of Guaranteed Securities As of September 30, 2021, Ventas, Inc.

Ventas Reports 2021 Third Quarter Results

Exhibit 99.1 Ventas Reports 2021 Third Quarter Results CHICAGO-(BUSINESS WIRE)-November 5, 2021-Ventas, Inc. (NYSE: VTR) (?Ventas? or the ?Company?) today reported results for the third quarter ended September 30, 2021. ?Ventas?s high-quality diversified portfolio demonstrated strength in the third quarter of 2021 despite the challenges of COVID-19 and a tight labor market. We are pleased with the

Ventas Completes Acquisition of New Senior Investment Group Inc.

Exhibit 99.1 Ventas Completes Acquisition of New Senior Investment Group Inc. CHICAGO & NEW YORK (BUSINESS WIRE) - Ventas, Inc. (NYSE: VTR) (?Ventas?) and New Senior Investment Group Inc. (?New Senior?) today announced that Ventas has completed its acquisition of New Senior in an all-stock transaction (the ?Transaction?), valued at approximately $2.3 billion, including New Senior debt assumed or r

Financial Statements and Exhibits, Completion of Acquisition or Disposition of Assets, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): September 21, 2021 Ventas, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-10989 61-1055020 (State or Other Jurisdiction of Incorporation) (Commission File Nu

New Senior Investment Group Stockholders Approve Merger with Ventas

Filed by Ventas, Inc. Pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 under the Securities Exchange Act of 1934 Subject Company: New Senior Investment Group Inc. Commission File No.: 333-258177 Date: September 14, 2021 New Senior Investment Group Stockholders Approve Merger with Ventas CHICAGO (September 14, 2021) - Ventas, Inc. (NYSE: VTR) (?Ventas?)

Underwriting Agreement, dated August 11, 2021, among Ventas Realty, Limited Partnership, Ventas, Inc. and the Underwriters named therein, relating to the 2.500% Senior Notes due 2031.

Exhibit 1.1 VENTAS REALTY, LIMITED PARTNERSHIP $500,000,000 2.500% Senior Notes due 2031 UNDERWRITING AGREEMENT Dated August 11, 2021 J.P. Morgan Securities LLC Mizuho Securities USA LLC UBS Securities LLC UNDERWRITING AGREEMENT August 11, 2021 J.P. Morgan Securities LLC Mizuho Securities USA LLC UBS Securities LLC As Representatives of the Underwriters listed on Schedule A hereto c/o J.P. Morgan