ILMN / Illumina, Inc. - Pengajuan SECLaporan Tahunan, Pernyataan Proksi

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☑ Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended June 29, 2025 ☐ Transition Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the transition period from to Commission File Number 001-35406 Illumina, Inc. (Exact nam

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 31, 2025 Illumina, Inc. (Exa

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 31, 2025 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporatio

Illumina Reports Financial Results for Second Quarter of Fiscal Year 2025

Investors: Brian Blanchett +1.858.291.6421 [email protected] Media: Christine Douglass [email protected] Illumina Reports Financial Results for Second Quarter of Fiscal Year 2025 •Revenue of $1.06 billion for Q2 2025, down 3% from Q2 2024 on both a reported and constant currency basis •GAAP operating margin of 20.2% and non-GAAP operating margin of 23.8% for Q2 2025 •GAAP diluted EPS of $1.49 and non-

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 22, 2025 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporatio

, dated June 22, 2025, between Illumina, Inc. and Standard BioTools Inc.*

Exhibit 2.1 CERTAIN IDENTIFIED INFORMATION HAS BEEN EXCLUDED FROM THE EXHIBIT BECAUSE IT IS BOTH NOT MATERIAL AND IS THE TYPE THAT THE REGISTRANT TREATS AS PRIVATE OR CONFIDENTIAL. REDACTED INFORMATION IS INDICATED BY [* * *]. STOCK PURCHASE AGREEMENT dated as of June 22, 2025 by and between ILLUMINA, INC. and STANDARD BIOTOOLS INC. TABLE OF CONTENTS Page ARTICLE I THE STOCK PURCHASE 1 Section 1.1

Illumina to acquire SomaLogic, accelerating its proteomics business and advancing the company’s multiomics strategy Combines highly complementary proteomics expertise with Illumina’s industry-leading product innovation and global market reach Positio

EX-99.1 Exhibit 99.1 Illumina to acquire SomaLogic, accelerating its proteomics business and advancing the company’s multiomics strategy Combines highly complementary proteomics expertise with Illumina’s industry-leading product innovation and global market reach Positions Illumina to achieve growth in a large, expanding market Illumina and SomaLogic have partnered in proteomics co-development sin

ILLUMINA, INC. SECOND AMENDED AND RESTATED 2015 STOCK AND INCENTIVE PLAN (as amended and restated February 4, 2025)

ILLUMINA, INC. SECOND AMENDED AND RESTATED 2015 STOCK AND INCENTIVE PLAN (as amended and restated February 4, 2025) 1.Purposes of the Plan. The purposes of this Second Amended and Restated 2015 Stock and Incentive Plan are to attract and retain the best available personnel for positions of substantial responsibility, to provide additional incentives to Service Providers, and to promote the success

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 21, 2025 Illumina, Inc. (Exac

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 21, 2025 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporation

Conflict Minerals Report

Conflict Minerals Report Introduction: This Report has been prepared pursuant to Rule 13p-1 under the Securities Exchange Act of 1934, as amended, for the reporting period from January 1 to December 31, 2024.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT Illumina, Inc. (Exact name of the registrant as specified in its charter) (Commission File Number)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT Illumina, Inc. (Exact name of the registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporation) (I.R.S. Employer Identification No.) 5200 Illumina Way, San Diego, CA 92122 (Address of principal executive office

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☑ Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended March 30, 2025 ☐ Transition Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the transition period from to Commission File Number 001-35406 Illumina, Inc. (Exact na

Illumina Reports Financial Results for First Quarter of Fiscal Year 2025

Investors: Brian Blanchett +1.858.291.6421 [email protected] Media: Christine Douglass [email protected] Illumina Reports Financial Results for First Quarter of Fiscal Year 2025 •Core Illumina revenue of $1.04 billion for Q1 2025, down 1% from Q1 2024 (flat on a constant currency basis) •GAAP operating margin of 15.8% and non-GAAP operating margin of 20.4% for Q1 2025 •GAAP diluted EPS of $0.82 and no

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 8, 2025 Illumina, Inc. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 8, 2025 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporation)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. 1)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. 1) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☒ Defi

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒        Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definit

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant  ☒         Filed by a Party other than the Registrant  ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(

Regulation FD Disclosure, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 24, 2025 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporati

Illumina Board of Directors Elects Dr. Scott Gottlieb Chair, Keith Meister to Join Board of Directors Stephen MacMillan to retire from the Board

Illumina Board of Directors Elects Dr. Scott Gottlieb Chair, Keith Meister to Join Board of Directors Stephen MacMillan to retire from the Board SAN DIEGO, March 25, 2025 /PRNewswire/ — Illumina, Inc. (NASDAQ: ILMN), a global leader in DNA sequencing and array-based technologies, today announced changes to its Board of Directors. Scott Gottlieb, MD, has been elected non-executive Chair of Illumina

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 18, 2025 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporati

Illumina addresses recent developments in China Announces Fiscal Year 2025 Non-GAAP Diluted EPS of Approximately $4.50

Investors: Salli Schwartz +1.858.291.6421 [email protected] Media: Bonny Fowler +1.740.641.5579 [email protected] Illumina addresses recent developments in China Announces Fiscal Year 2025 Non-GAAP Diluted EPS of Approximately $4.50 San Diego, March 10, 2025 /PRNewswire/ - Illumina, Inc. (Nasdaq: ILMN) (“Illumina” or the “company”) today responded to the March 4, 2025 notice from the China Ministry of

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 10, 2025 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporati

Subsidiaries of Illumina

SUBSIDIARIES OF THE COMPANY The following is a list of subsidiaries of Illumina, Inc.

Insider Trading Policy, Adopted July 30, 2024

ILLUMINA, INC. Insider Trading Compliance Program To take an active role in the prevention of insider trading violations by its officers, directors, employees and other related individuals, Illumina has adopted the policies and procedures described in this Memorandum. I.Adoption of Insider Trading Policy. Illumina has adopted the Insider Trading Policy attached as Exhibit A (the “Policy”), which p

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-K ☑ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-K ☑ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 29, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-35406 Illumina, Inc. (Exact nam

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 6, 2025 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpora

Illumina Reports Financial Results for Fourth Quarter and Fiscal Year 2024

Investors: Salli Schwartz +1.858.291.6421 [email protected] Media: Bonny Fowler +1.740.641.5579 [email protected] Illumina Reports Financial Results for Fourth Quarter and Fiscal Year 2024 •Core Illumina revenue of $1.1 billion for Q4 2024, up 1% from Q4 2023 on both a reported and constant currency basis; revenue of $4.3 billion for fiscal year 2024, down 2% from fiscal year 2023 on both a reported a

Illumina Announces Preliminary Unaudited Financial Results for Fourth Quarter and Fiscal Year 2024 and Provides Preliminary Outlook for Fiscal Year 2025

Investors: Salli Schwartz +1.858.291.6421 [email protected] Media: Bonny Fowler +1.740.641.5579 [email protected] Illumina Announces Preliminary Unaudited Financial Results for Fourth Quarter and Fiscal Year 2024 and Provides Preliminary Outlook for Fiscal Year 2025 San Diego, January 14, 2025 /PRNewswire/ - Illumina, Inc. (Nasdaq: ILMN) (“Illumina” or the “company”) today announced unaudited prelimin

Costs Associated with Exit or Disposal Activities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K/A Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 21, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporat

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 14, 2025 Illumina, Inc. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 14, 2025 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpora

ILMN / Illumina, Inc. / Capital World Investors - SEC SCHEDULE 13G Passive Investment

SC 13G 1 SEC13GFiling.htm SEC SCHEDULE 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Illumina, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 452327109 (CUSIP Number) November 29, 2024 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designat

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☑ Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended September 29, 2024 ☐ Transition Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the transition period from to Commission File Number 001-35406 Illumina, Inc. (Exac

Illumina Reports Financial Results for Third Quarter of Fiscal Year 2024

Investors: Salli Schwartz +1.858.291.6421 [email protected] Media: Bonny Fowler +1.740.641.5579 [email protected] Illumina Reports Financial Results for Third Quarter of Fiscal Year 2024 •Core Illumina revenue of $1.1 billion for Q3 2024, down 2% from Q3 2023 and on a constant currency basis •Core Illumina GAAP operating margin of 68.6% and non-GAAP operating margin of 22.6% for Q3 2024 •Core Illumina

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 4, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpora

Separation Agreement between Illumina, Inc. and Charles Dadswell, dated October 3, 2024

Exhibit 10.2 Illumina, Inc. 5200 Illumina Way San Diego, CA 92122 USA tel 858.202.4500 fax 858.202.4766 www.illumina.com SEPARATION AGREEMENT AND GENERAL RELEASE OF ALL CLAIMS This Separation Agreement and General Release of All Claims (“Agreement”) is made by and between Illumina, Inc. (“Illumina” or “the Company”) and Charles Dadswell (“Employee”), collectively (“the Parties”), with respect to t

Advisory Agreement between Illumina, Inc. and Charles Dadswell, dated October 3, 2024

Exhibit 10.1 ADVISORY AGREEMENT This ADVISORY AGREEMENT (the "Agreement") is entered into by and between lllumina, Inc. (the "Company") and Charles Dadswell ("Executive") effective on the date of Executive’s signature of execution, for the purpose of providing a smooth, professional and effective transition of Executive’s duties and responsibilities in connection with Executive’s mutually agreed s

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 3, 2024 Illumina, Inc. (E

[ UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 3, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware (State or other jurisdiction of incorporation) 33-0

Officer’s Certificate, dated September 9, 2024, setting forth the terms and form of the Notes

Exhibit 4.2 ILLUMINA, INC. OFFICER’S CERTIFICATE September 9, 2024 Reference is made to the Indenture dated as of March 12, 2021 (as so supplemented by this Officer’s Certificate, the “Indenture”) by and between Illumina, Inc. (the “Issuer”) and U.S. Bank Trust Company, National Association (as successor in interest to U.S. Bank National Association), as trustee (the “Trustee”). The Trustee is the

Underwriting Agreement, dated September 4, 2024, between the Company and J.P. Morgan Securities LLC and Goldman Sachs & Co. LLC, as representatives of the several underwriters named therein

Exhibit 1.1 $500,000,000 Illumina, Inc. 4.650% Notes due 2026 Underwriting Agreement September 4, 2024 J.P. Morgan Securities LLC Goldman Sachs & Co. LLC As representatives (the “Representatives”) of the several Underwriters named in Schedule I hereto c/o J.P. Morgan Securities LLC 383 Madison Avenue New York, New York 10179 c/o Goldman Sachs & Co. LLC 200 West Street New York, New York 10282-2198

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 4, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpor

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 4, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpor

Calculation of Filing Fee Tables 424 (b)(2) ( Form Type) Illumina, Inc. (Exact Name of Registrant as Specified in Its Charter) Table 1: Newly Registered and Carry Forward Securities

Exhibit 107.1 Calculation of Filing Fee Tables 424 (b)(2) ( Form Type) Illumina, Inc. (Exact Name of Registrant as Specified in Its Charter) Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Car

$500,000,000 $500,000,000 4.650% Notes due 2026

Table of Contents Filed Pursuant to Rule 424(b)(2) Registration Statement No. 333-281921 PROSPECTUS SUPPLEMENT (to Prospectus Dated September 4, 2024) $500,000,000 $500,000,000 4.650% Notes due 2026 We are offering $500,000,000 aggregate principal amount of 4.650% notes due 2026 (the “Notes”). Interest on the Notes is payable semiannually in arrears on March 9 and September 9 of each year, beginni

ILLUMINA, INC. FINAL TERM SHEET September 4, 2024 $500,000,000 4.650% Notes due 2026 Issuer: Illumina, Inc. Format: SEC Registered Title of Securities: 4.650% Senior Notes due 2026 (the “Notes”) Ratings* Moody’s: Baa3 (Stable) S&P: BBB (Stable) Fitch

Filed pursuant to Rule 433 Registration No. 333-281921 Issuer Free Writing Prospectus dated September 4, 2024 Relating to Preliminary Prospectus Supplement dated September 4, 2024 ILLUMINA, INC. FINAL TERM SHEET September 4, 2024 $500,000,000 4.650% Notes due 2026 Issuer: Illumina, Inc. Format: SEC Registered Title of Securities: 4.650% Senior Notes due 2026 (the “Notes”) Ratings* Moody’s: Baa3 (S

Form T-1 Statement of Eligibility under the Trust Indenture Act of 1939, as amended, of U.S. Bank Trust Company, National Association.

Exhibit 25.1 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM T-1 STATEMENT OF ELIGIBILITY UNDER THE TRUST INDENTURE ACT OF 1939 OF A CORPORATION DESIGNATED TO ACT AS TRUSTEE ☐ Check if an Application to Determine Eligibility of a Trustee Pursuant to Section 305(b)(2) U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION (Exact name of Trustee as specified in its charter) 91-1821036 (I.R.S.

As filed with the Securities and Exchange Commission on September 4, 2024

As filed with the Securities and Exchange Commission on September 4, 2024 Registration No.

Subject to Completion Preliminary Prospectus Supplement dated September 4, 2024

Table of Contents Filed Pursuant to Rule 424(b)(2) Registration Statement No. 333-281921 The information contained in this preliminary prospectus supplement is not complete and may be changed. This preliminary prospectus supplement and the accompanying prospectus are not an offer to sell the securities and are not soliciting an offer to buy the senior notes offered hereby in any jurisdiction where

Filing Fee Table.

Exhibit 107.1 Calculation of Filing Fee Tables Form S-3 (Form Type) Illumina, Inc. (Exact Name of Registrant as Specified in Its Charter) Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee  Rate  Amount of Registration Fee Carr

GRAL / Grail Inc / ILLUMINA, INC. - SC 13G Passive Investment

SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.

Separation Agreement and General Release of All Claims by and between Joydeep Goswami and Illumina, Inc. dated as of July 2, 2024

SEPARATION AGREEMENT AND GENERAL RELEASE OF ALL CLAIMS This Separation Agreement and General Release of All Claims (“Agreement”) is made by and between Illumina, Inc.

Retention Agreement by and between Joydeep Goswami and Illumina, Inc. dated as of April 8, 2024

RETENTION AGREEMENT This RETENTION AGREEMENT (the "Agreement") is entered into by and between lllumina, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☑ Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended June 30, 2024 ☐ Transition Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the transition period from to Commission File Number 001-35406 Illumina, Inc. (Exact nam

Amended and Restated Bylaws of Illumina, Inc., effective as of August 5, 2024

BYLAWS OF ILLUMINA, INC. Amended and Restated as of August 5, 2024 TABLE OF CONTENTS ARTICLE I CORPORATE OFFICES 1 1.1 REGISTERED OFFICE 1 1.2 OTHER OFFICES 1 ARTICLE II MEETINGS OF STOCKHOLDERS 1 2.1 PLACE OF MEETINGS 1 2.2 ANNUAL MEETING 1 2.3 SPECIAL MEETING 1 2.4 NOTICE OF STOCKHOLDERS’ MEETINGS 3 2.5 MANNER OF GIVING NOTICE; AFFIDAVIT OF NOTICE 3 2.6 QUORUM 3 2.7 ADJOURNED MEETING; NOTICE 4 2

Illumina Reports Financial Results for Second Quarter of Fiscal Year 2024

Investors: Salli Schwartz +1.858.291.6421 [email protected] Media: Bonny Fowler +1.740.641.5579 [email protected] Illumina Reports Financial Results for Second Quarter of Fiscal Year 2024 •Core Illumina revenue of $1.09 billion for Q2 2024, down 6% from Q2 2023 (down 6% on a constant currency basis) and up 3% from Q1 2024 •Core Illumina GAAP operating margin of 40.5% and non-GAAP operating margin of 2

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 6, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporati

Financial Statements and Exhibits, Completion of Acquisition or Disposition of Assets

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K/A Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 21, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporat

Costs Associated with Exit or Disposal Activities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K/A Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 3, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporati

UNAUDITED PRO FORMA CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

Exhibit 99.1 UNAUDITED PRO FORMA CONDENSED CONSOLIDATED FINANCIAL STATEMENTS Overview On June 24, 2024 (the “Distribution Date”), Illumina, Inc. (“Illumina” or the “Company”) completed the previously announced separation (the “Spin-Off”) of its wholly owned subsidiary, GRAIL, LLC, into a separate, independent publicly traded company, GRAIL, Inc. (“GRAIL”). The Spin-Off was structured as a tax-free

Employee Matters Agreement, dated June 21, 2024, between GRAIL, LLC and Illumina, Inc.

Exhibit 10.2 EMPLOYEE MATTERS AGREEMENT by and between ILLUMINA, INC. and GRAIL, LLC (to be converted into GRAIL, INC.) Dated as of June 21, 2024 TABLE OF CONTENTS Page ARTICLE I Definitions and Interpretation Section 1.1. General 1 Section 1.2. References; Interpretation 5 ARTICLE II General Principles Section 2.1. Nature of Liabilities 5 Section 2.2. Assumption and Retention of Liabilities Gener

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 21, 2024 Illumina, Inc. (Exa

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 21, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporatio

Tax Matters Agreement, dated June 21, 2024, between GRAIL, LLC and Illumina, Inc.

Exhibit 10.1 EXECUTION VERSION TAX MATTERS AGREEMENT BY AND BETWEEN ILLUMINA, INC. AND GRAIL, LLC (to be converted into GRAIL, INC.) DATED AS OF June 21, 2024 TABLE OF CONTENTS Page Section 1. Definition of Terms 1 Section 2. Allocation of Tax Liabilities and Tax-Related Losses 9 Section 2.01. General Rule 9 Section 2.02. Allocation Principles 10 Section 2.03. Allocation Conventions 10 Section 3.

Stockholder and Registration Rights Agreement, Dated June 21, 2024, between GRAIL, LLC and Illumina, Inc.

Exhibit 10.3 EXECUTION VERSION STOCKHOLDER AND REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of June 21, 2024, between Illumina, Inc., a Delaware corporation (“Illumina”), and GRAIL, LLC, a Delaware limited liability company (“GRAIL LLC”), to be converted to a corporation and renamed GRAIL, Inc. (the “Company”). WHEREAS, Illumina and the Company have entered into a Separation and Dist

Fourth Amendment to the Amended and Restated Supply and Commercialization Agreement, dated June 21, 2024, by and between Illumina, Inc. and GRAIL, LLC*

Exhibit 10.4 EXECUTION VERSION Certain information has been excluded from this agreement (indicated by “[***]”) because such information is both (a) not material and (b) is the type that the registrant customarily and actually treats as private or confidential. FOURTH AMENDMENT TO AMENDED AND RESTATED SUPPLY AND COMMERCIALIZATION AGREEMENT This Fourth Amendment to the Amended and Restated Supply a

aration and Distribution Agreement, dated June

Exhibit 2.1 EXECUTION VERSION SEPARATION AND DISTRIBUTION AGREEMENT BY AND BETWEEN ILLUMINA, INC. AND GRAIL, LLC (to be converted into GRAIL, INC.) DATED AS OF June 21, 2024 TABLE OF CONTENTS ARTICLE I DEFINITIONS 2 Section 1.1. Definitions 2 Section 1.2. Interpretation 8 ARTICLE II SEPARATION 9 Section 2.1. Allocation of GRAIL Assets, Illumina Assets, GRAIL Liabilities and Illumina Liabilities 9

Illumina completes the divestiture of GRAIL

Exhibit 99.1 Illumina completes the divestiture of GRAIL • GRAIL spin-off complete; GRAIL to begin regular way trading as “GRAL” on June 25 • Illumina to issue second quarter 2024 results on August 6; leadership to present Strategy Update on August 13 SAN DIEGO, June 24, 2024 /PRNewswire/—Illumina, Inc. (NASDAQ: ILMN) today announced the successful completion of the spin-off of GRAIL. This milesto

364-Day Delayed Draw Credit Agreement, dated as of June 17, 2024, among the Company, as the borrower, the lenders from time to time party thereto and JPMorgan Chase Bank, N.A., as administrative agent

Exhibit 10.1 EXECUTION VERSION 364-DAY DELAYED DRAW TERM LOAN CREDIT AGREEMENT dated as of June 17, 2024 among ILLUMINA, INC., as the Borrower, The Lenders Party Hereto, and JPMORGAN CHASE BANK, N.A., as the Administrative Agent JPMORGAN CHASE BANK, N.A., as Sole Lead Arranger and Sole Bookrunner, Goldman Sachs Bank USA, Bank of America, N.A, and BNP Paribas, as Syndication Agents Table Of Content

Entry into a Material Definitive Agreement, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 17, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporatio

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K/A Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 3, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporati

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 3, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporation

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 16, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporation

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT Illumina, Inc. (Exact name of the registrant as specified in its charter) (Commission File Number)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT Illumina, Inc. (Exact name of the registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporation) (I.R.S. Employer Identification No.) 5200 Illumina Way, San Diego, CA 92122 (Address of principal executive office

Conflict Minerals Report

Conflict Minerals Report Introduction: This Report has been prepared pursuant to Rule 13p-1 under the Securities Exchange Act of 1934, as amended, for the reporting period from January 1 to December 31, 2023.

eparation Agreement and Release of All Cl

SEPARATION AGREEMENT AND GENERAL RELEASE OF ALL CLAIMS This Separation Agreement and General Release of All Claims (“Agreement”) is made by and between Illumina, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☑ Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended March 31, 2024 ☐ Transition Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the transition period from to Commission File Number 001-35406 Illumina, Inc. (Exact na

Costs Associated with Exit or Disposal Activities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K/A Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 21, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporat

Illumina Reports Financial Results for First Quarter of Fiscal Year 2024

Investors: Salli Schwartz +1.858.291.6421 [email protected] Media: Bonny Fowler +1.740.641.5579 [email protected] Illumina Reports Financial Results for First Quarter of Fiscal Year 2024 •Core Illumina revenue of $1.06 billion for Q1 2024, down 2% from Q1 2023 (down 2% on a constant currency basis) •Core Illumina GAAP operating margin of 11.0% and non-GAAP operating margin of 20.6% for Q1 2024 •Reiter

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 2, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporation)

Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 12, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporati

Illumina appoints Ankur Dhingra Chief Financial Officer, Jakob Wedel Chief Strategy and Corporate Development Officer Joydeep Goswami to serve as advisor through June 30 Illumina reaffirms Q1 2024 and full-year 2024 financial guidance

Exhibit 99.1 For release April 9, 2024 Illumina appoints Ankur Dhingra Chief Financial Officer, Jakob Wedel Chief Strategy and Corporate Development Officer Joydeep Goswami to serve as advisor through June 30 Illumina reaffirms Q1 2024 and full-year 2024 financial guidance SAN DIEGO, April 9, 2024 /PRNewswire/ - Illumina, Inc. (NASDAQ: ILMN), a global leader in DNA sequencing and array-based techn

Regulation FD Disclosure, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 4, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporatio

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒        Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Prox

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant  ☒         Filed by a Party other than the Registrant  ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(

Subsidiaries of Illumina

SUBSIDIARIES OF THE COMPANY The following is a list of subsidiaries of Illumina, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-K ☑ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-K ☑ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-35406 Illumina, Inc. (Exact nam

Compensation Recovery/Clawback Policy - Adopted May 2, 2023

ILLUMINA, INC. Compensation Recovery Policy The Board of Directors of Illumina, Inc. (the “Company”) has adopted this Compensation Recovery Policy (the “Policy”), as required by Section 10D of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), Rule 10D-1 under the Exchange Act and the Nasdaq National Market listing standards. This Policy is intended to further strengthen the rel

ILMN / Illumina, Inc. / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SC 13G/A 1 tv01168-illuminainc.htm SCHEDULE 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 9)* Name of issuer: Illumina Inc Title of Class of Securities: Common Stock CUSIP Number: 452327109 Date of Event Which Requires Filing of this Statement: December 29, 2023 Check the appropriate box to designate the rule

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 8, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpora

Illumina Reports Financial Results for Fourth Quarter and Fiscal Year 2023

Investors: Salli Schwartz +1.858.291.6421 [email protected] Media: David McAlpine +1.347.327.1336 [email protected] Illumina Reports Financial Results for Fourth Quarter and Fiscal Year 2023 •Revenue of $1.12 billion for Q4 2023, up 4% from Q4 2022 (up 4% on a constant currency basis) •Revenue of $4.50 billion for fiscal year 2023, down 2% from fiscal year 2022 (flat on a constant currency basis) •Shi

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 9, 2024 Illumina, Inc. (E

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 9, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporat

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K/A Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 21, 2023 Illumina, Inc. (E

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K/A Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 21, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporat

Illumina Announces Preliminary Financial Results for Fourth Quarter and Fiscal Year 2023

Investors: Salli Schwartz +1.858.291.6421 [email protected] Media: David McAlpine +1.347.327.1336 [email protected] Illumina Announces Preliminary Financial Results for Fourth Quarter and Fiscal Year 2023 San Diego, January 9, 2024 /PRNewswire/ - Illumina, Inc. (Nasdaq: ILMN) (“Illumina” or the “company”) today announced unaudited preliminary financial results for the fourth quarter and fiscal year 20

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 4, 2024 Illumina, Inc. (E

falseIllumina, Inc.0001110803CA00011108032023-08-312023-08-31 [ UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 4, 2024 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number

Carl C. Icahn Issues Open Letter to Stockholders of Illumina, Inc.

Exhibit 1 Carl C. Icahn Issues Open Letter to Stockholders of Illumina, Inc.   Sunny Isles Beach, Florida, December 18, 2023 - Today, Carl C. Icahn released the following open letter to the stockholders of Illumina, Inc. (NASDAQ: ILMN). CARL C. ICAHN 16690 Collins Avenue, Suite PH-1 Sunny Isles Beach, FL 33160     December 18, 2023 Dear Fellow Stockholders: Our campaign at Illumina has had three m

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant [ ] Filed by a Party other than the Registrant [X] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K/A Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 21, 2023 Illumina, Inc. (E

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K/A Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 21, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporat

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☑ Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended October 1, 2023 ☐ Transition Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the transition period from to Commission File Number 001-35406 Illumina, Inc. (Exact n

aims by and between Illumina, Inc. and Phil Febbo, dates

SEPARATION AGREEMENT AND GENERAL RELEASE OF ALL CLAIMS This Separation Agreement and General Release of All Claims (“Agreement”) is made by and between Illumina, Inc.

Illumina Reports Financial Results for Third Quarter of Fiscal Year 2023

Investors: Salli Schwartz +1.858.291.6421 [email protected] Media: David McAlpine +1.347.327.1336 [email protected] Illumina Reports Financial Results for Third Quarter of Fiscal Year 2023 •Welcomed new CEO Jacob Thaysen, Ph.D., who started with Illumina on September 25, 2023 •With respect to GRAIL, continue to proceed quickly: retained advisors and preparing for sale and capital markets transaction o

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K/A Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 31, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpor

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 9, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpora

Amended and Restated Offer Letter to Jacob Thaysen, dated November 8, 2023

Exhibit 10.3 Revised November 7, 2023 Jacob Thaysen Dear Jacob: On behalf of Illumina, Inc. (“Illumina,” “us,” “our” or “we”), I am happy to extend an offer to you for the position of Chief Executive Officer, reporting to our Board of Directors (the “Board”). As soon as practicable after the State Date (as defined below), you will be appointed as a member of the Board (in your capacity as Chief Ex

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K/A Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 25, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporati

ILMN / Illumina Inc / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SC 13G/A 1 tv0002-illuminainc.htm SCHEDULE 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 8)* Name of issuer: Illumina Inc. Title of Class of Securities: Common Stock CUSIP Number: 452327109 Date of Event Which Requires Filing of this Statement: September 29, 2023 Check the appropriate box to designate the rule

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 5, 2023 Illumina, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 5, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpor

dated August 31, 2023

Exhibit 10.1 Jacob Thaysen Dear Jacob: On behalf of Illumina, Inc. (“Illumina,” “us,” “our” or “we”), I am happy to extend an offer to you for the position of Chief Executive Officer, reporting to our Board of Directors (the “Board”). As soon as practicable after the State Date (as defined below), you will be appointed as a member of the Board (in your capacity as Chief Executive Officer) without

Illumina’s Board Appoints Jacob Thaysen, Ph.D. as its New Chief Executive Officer

Exhibit 99.1 PRESS RELEASE Illumina’s Board Appoints Jacob Thaysen, Ph.D. as its New Chief Executive Officer SAN DIEGO, September 5, 2023 /PRNewswire/ - Illumina, Inc. (NASDAQ: ILMN), a global leader in DNA sequencing and array-based technologies, today announced that its Board of Directors has appointed Jacob Thaysen, Ph.D., senior vice president of Agilent Technologies and president of its Life

Change in Control Severance Agreement between Illumina, Inc. and Jacob Thaysen

Exhibit 10.2 CHANGE IN CONTROL SEVERANCE AGREEMENT This CHANGE IN CONTROL SEVERANCE AGREEMENT (this “Agreement”), is made as of the 31st day of August, 2023 by and between ILLUMINA, INC., a Delaware corporation (the “Company”) and Jacob Thaysen (the “Executive”). WHEREAS, the Executive will be a key member of the management of the Company as of the Effective Date (as defined below), and the Board

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 31, 2023 Illumina, Inc. (E

[ UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 31, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware (State or other jurisdiction of incorporation) 33-0

2000 Employee Stock Purchase Plan, as amended and restated through May 2, 2023

ILLUMINA, INC. 2000 EMPLOYEE STOCK PURCHASE PLAN As Amended and Restated May 2, 2023 The following constitute the provisions of the 2000 Employee Stock Purchase Plan of Illumina, Inc. 1.Purpose.The purpose of the Purchase Plan is to provide Employees of the Company and its Designated Companies with an opportunity to purchase Common Stock through accumulated payroll deductions. Unless otherwise det

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☑ Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended July 2, 2023 ☐ Transition Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the transition period from to Commission File Number 001-35406 Illumina, Inc. (Exact name

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 9, 2023 Illumina, Inc. (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 9, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporati

Illumina Reports Financial Results for Second Quarter of Fiscal Year 2023

Investors: Salli Schwartz +1.858.291.6421 [email protected] Media: David McAlpine +1.347.327.1336 [email protected] Illumina Reports Financial Results for Second Quarter of Fiscal Year 2023 •Revenue of $1.18 billion for Q2 2023, up 1% from Q2 2022 (up 3% on a constant currency basis) and up 8% from Q1 2023 •Shipped 109 NovaSeq X instruments in Q2 2023; boosting our supply capacity to more than 390 ins

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2023 Illumina, Inc. (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporati

Dr. Steven Barnard Appointed Chief Technology Officer

Exhibit 99.1 Dr. Steven Barnard Appointed Chief Technology Officer SAN DIEGO, August 9, 2023 /PRNewswire/ - Illumina, Inc. (NASDAQ: ILMN), a global leader in DNA sequencing and array-based technologies, today announced Dr. Steven Barnard, Illumina’s Vice President and Head of Global Advanced Science, will serve as its next Chief Technology Officer (CTO), effective immediately. Dr. Alex Aravanis, w

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K/A Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 8, 2023 Illumina, Inc. (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K/A Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 8, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporati

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 21, 2023 Illumina, Inc. (Exa

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 21, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporatio

Illumina announces CEO transition plan

Exhibit 99.1 Illumina announces CEO transition plan SAN DIEGO, June 11, 2023 /PRNewswire/ - Illumina Inc. (NASDAQ: ILMN), a global leader in DNA sequencing and array-based technologies, today announced that its Board of Directors has accepted the resignation of Francis deSouza as Illumina's Chief Executive Officer and as a Director, effective Sunday, June 11. Charles Dadswell, Senior Vice Presiden

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 8, 2023 Illumina, Inc. (Exac

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 8, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporation

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 1, 2023 Illumina, Inc. (Exac

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 1, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporation

Illumina's Board of Directors elects two experienced Independent Directors to Board Stephen P. MacMillan, Hologic CEO, named non-executive Chair of Illumina's Board Scott B. Ullem, CFO of Edwards Lifesciences, also named to Board

Exhibit 99.1 Illumina's Board of Directors elects two experienced Independent Directors to Board Stephen P. MacMillan, Hologic CEO, named non-executive Chair of Illumina's Board Scott B. Ullem, CFO of Edwards Lifesciences, also named to Board SAN DIEGO, June 2, 2023 /PRNewswire/ - Illumina, Inc. (NASDAQ: ILMN), a global leader in DNA sequencing and array-based technologies, today announced a serie

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT Illumina, Inc. (Exact name of the registrant as specified in its charter) (Commission File Number)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT Illumina, Inc. (Exact name of the registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporation) (I.R.S. Employer Identification No.) 5200 Illumina Way, San Diego, CA 92122 (Address of principal executive office

Conflict Minerals Report

Conflict Minerals Report Introduction: This Report has been prepared pursuant to Rule 13p-1 under the Securities Exchange Act of 1934, as amended, for the reporting period from January 1 to December 31, 2022.

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 25, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporation

Illumina Announces Preliminary Results of Annual Meeting Illumina shareholders re-elect eight of nine Illumina directors

Exhibit 99.1 Illumina Announces Preliminary Results of Annual Meeting Illumina shareholders re-elect eight of nine Illumina directors SAN DIEGO, May 25, 2023 /PRNewswire/ - Illumina (NASDAQ: ILMN), a global leader in DNA sequencing and array-based technologies, today announced that based on the preliminary results of its 2023 Annual Meeting, Illumina shareholders have voted to elect eight of nine

(State or other jurisdiction of incorporation)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 25, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporation

Carl C. Icahn Issues Open Letter to Shareholders of Illumina, Inc.

Exhibit 1 Carl C. Icahn Issues Open Letter to Shareholders of Illumina, Inc. Sunny Isles Beach, Florida, May 19, 2023 - Today, Carl C. Icahn released the following open letter to the shareholders of Illumina, Inc. (NASDAQ: ILMN). THE NEED FOR CHANGE IS CLEAR! VOTE FOR THE THREE ICAHN NOMINEES! Investor Contacts: HKL & Co., LLC Peter Harkins / Jordan Kovler (212) 468-5390 / (212) 468-5384 pharkins@

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant [ ] Filed by a Party other than the Registrant [X] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

Carl C. Icahn Issues Open Letter to Shareholders of Illumina, Inc.

Exhibit 1 Carl C. Icahn Issues Open Letter to Shareholders of Illumina, Inc. Sunny Isles Beach, Florida, May 15, 2023 - Today, Carl C. Icahn released the following open letter to the shareholders of Illumina, Inc. (NASDAQ: ILMN). ISS RECOMMENDS THAT ILLUMINA SHAREHOLDERS VOTE AGAINST CHAIRMAN JOHN THOMPSON AND FOR ICAHN NOMINEE ANDREW TENO Investor Contacts: HKL & Co., LLC Peter Harkins / Jordan K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant [ ] Filed by a Party other than the Registrant [X] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant [ ] Filed by a Party other than the Registrant [X] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

Carl C. Icahn Issues Open Letter to Shareholders of Illumina, Inc.

Exhibit 1 Carl C. Icahn Issues Open Letter to Shareholders of Illumina, Inc. Sunny Isles Beach, Florida, May 11, 2023 - Today, Carl C. Icahn released the following open letter to the shareholders of Illumina, Inc. (NASDAQ: ILMN). Glass Lewis Recommends AGAINST CEO Francis deSouza Glass Lewis Recommends AGAINST Chair John Thompson Glass Lewis Recommends FOR Two Icahn Nominees Investor Contacts: HKL

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant [ ] Filed by a Party other than the Registrant [X] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

Carl C. Icahn Issues Open Letter to Shareholders of Illumina, Inc.

Exhibit 1 Carl C. Icahn Issues Open Letter to Shareholders of Illumina, Inc. Sunny Isles Beach, Florida, April 28, 2023 — Today, Carl C. Icahn released the following open letter to the shareholders of Illumina, Inc. (NASDAQ: ILMN). Investor Contacts: HKL & Co., LLC Peter Harkins / Jordan Kovler (212) 468-5390 / (212) 468-5384 [email protected] / [email protected] CARL C. ICAHN 16690 Collins Avenu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

Carl C. Icahn Issues Open Letter to Shareholders of Illumina, Inc.

Exhibit 1 Carl C. Icahn Issues Open Letter to Shareholders of Illumina, Inc. Sunny Isles Beach, Florida, May 8, 2023 - Today, Carl C. Icahn released the following open letter to the shareholders of Illumina, Inc. (NASDAQ: ILMN). SPOTLIGHT ON TEAM FRANCIS: WHY DIDN’T THEY GET A FAIRNESS OPINION? Investor Contacts: HKL & Co., LLC Peter Harkins / Jordan Kovler (212) 468-5390 / (212) 468-5384 pharkins

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant [ ] Filed by a Party other than the Registrant [X] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☑ Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended April 2, 2023 ☐ Transition Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the transition period from to Commission File Number 001-35406 Illumina, Inc. (Exact nam

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the app

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549   SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )     Filed by the Registrant [ ]   Filed by a Party other than the Registrant [x]   Check the appropriate box:   [   ] Preliminary Proxy Statement [   ]   Confidential, for Use of the Commission Only (as permitted b

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant [ ] Filed by a Party other than the Registrant [x] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant [ ] Filed by a Party other than the Registrant [x] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant [ ] Filed by a Party other than the Registrant [x] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☐ Filed by a Party other than the Registrant ☒ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14-a6(e)(2)) ☒ Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

Illumina Reports Financial Results for First Quarter of Fiscal Year 2023; Announces Commitment to Accelerate Margin Growth

Investors: Salli Schwartz +1.858.291.6421 [email protected] Media: David McAlpine +1.347.327.1336 [email protected] Illumina Reports Financial Results for First Quarter of Fiscal Year 2023; Announces Commitment to Accelerate Margin Growth •Revenue of $1.09 billion for Q1 2023, up 1% from Q4 2022; down 11% from Q1 2022 (down 9% on a constant currency basis) •GAAP diluted EPS of $0.02 for Q1 2023, compa

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 25, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporati

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant [ ] Filed by a Party other than the Registrant [x] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant [ ] Filed by a Party other than the Registrant [x] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. 1)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. 1) Filed by the Registrant ☐ Filed by a Party other than the Registrant ☒ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14-a6(e)(2)) ☐ Defi

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

DEFA14A 1 defa14a.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☒ Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

DEFA14A 1 defa14a.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐

Illumina, Inc. (“ILMN”) Case for Change Spring 2023

Exhibit 1 Illumina, Inc. (“ILMN”) Case for Change Spring 2023 2 TABLE OF CONTENTS • Executive Summary • Value Destruction & Share Price Underperformance • GRAIL Timeline & Failures • GRAIL Going Forward • Core Illumina Failures • No Accountability • Our Plan • Appendix 3 EXECUTIVE SUMMARY ILMN’S DESIRE TO OWN GRAIL AT ALL COSTS HAS DESTROYED $50 BILLION OF SHAREHOLDER VALUE. • ILMN created a divis

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant [ ] Filed by a Party other than the Registrant [X] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☐ Filed by a Party other than the Registrant ☒ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14-a6(e)(2)) ☐ Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. 1)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. 1) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defi

Daniel J. Cerqueira

CORRESP Daniel J. Cerqueira [email protected] T +212-474-1156 New York April 7, 2023 Illumina, Inc. PREC14A filed March 30, 2023 SEC File No. 001-35406 Dear Mr. Hindin and Ms. Chalk: This letter is submitted on behalf of Illumina, Inc. (the “Company”) in response to the comments from the staff of the Division of Corporation Finance and the Office of Mergers & Acquisitions (the “Staff”) of the

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant [ ] Filed by a Party other than the Registrant [x] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant [ ] Filed by a Party other than the Registrant [x] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than t h e Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy Sta

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant [ ] Filed by a Party other than the Registrant [x] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

DEFA14A 1 defa14a.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant [ ] Filed by a Party other than the Registrant [x] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant [ ] Filed by a Party other than the Registrant [x] Check the appropriate box:   [  ] Preliminary Proxy Statement [  ] Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

DFAN14A 1 n2779x105-dfan14a.htm DFAN14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549   SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )     Filed by the Registrant [ ]   Filed by a Party other than the Registrant [x]   Check the appropriate box:   [  ] Preliminary Proxy Statement [  ] Confidential, for Use of

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Table Form S-8 (Form Type) Illumina, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered (1)(2) Proposed Maximum Offering Price Per Unit (3) Maximum Aggregate Offering Price (3) Fee Rate Amount of Registration Fee (4) Equity Common Stock, par

Power of Attorney (included with signature page).

S-8 1 d473009ds8.htm S-8 As filed with the Securities and Exchange Commission on March 1, 2023 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 ILLUMINA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 33-0804655 (State or Other Jurisdiction of Incorporation or Organiz

Form of Option Agreement for Employees Under 2015 Stock and Incentive Plan

ILLUMINA, INC. 2015 STOCK AND INCENTIVE PLAN STOCK OPTION AGREEMENT Unless otherwise defined herein, all capitalized terms shall have the meanings assigned to them in the Illumina, Inc. 2015 Stock and Incentive Plan (the “Plan”). I.NOTICE OF GRANT You have been granted an option to purchase shares of Common Stock of the Company, subject to the terms and conditions of the Plan and this Option Agree

Subsidiaries of Illumina

SUBSIDIARIES OF THE COMPANY The following is a list of subsidiaries of Illumina, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-K ☑ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-K ☑ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended January 1, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-35406 Illumina, Inc. (Exact name

ILMN / Illumina, Inc. / EDGEWOOD MANAGEMENT LLC Passive Investment

SC 13G/A 1 d993833513g-a.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No. 1)* Illumina Inc. (Name of Issuer) Common Stock, $0.01 par value (Title of Class of Securities) 452327109 (CUSIP Num

ILMN / Illumina, Inc. / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SC 13G/A 1 tv01131-illuminainc.htm SCHEDULE 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 7)* Name of issuer: Illumina Inc. Title of Class of Securities: Common Stock CUSIP Number: 452327109 Date of Event Which Requires Filing of this Statement: December 30, 2022 Check the appropriate box to designate the rule

Form of Performance Stock Unit Agreement (Relative TSR) for Employees Under Amended and Restated 2015 Stock and Incentive Plan

ILLUMINA, INC. AMENDED AND RESTATED 2015 STOCK AND INCENTIVE PLAN PERFORMANCE STOCK UNIT AGREEMENT FOR EMPLOYEES This PERFORMANCE STOCK UNIT AGREEMENT (this “Agreement”) made as of this day of , 20, between Illumina, Inc., a Delaware corporation (the “Company”), and (the “Participant”), is made pursuant to the terms of the Company’s Amended and Restated 2015 Stock and Incentive Plan (the “Plan”).

Amended and Restated 2015 Stock and Incentive Plan

ILLUMINA, INC. AMENDED AND RESTATED 2015 STOCK AND INCENTIVE PLAN (as amended and restated February 1, 2023) 1.Purposes of the Plan. The purposes of this Amended and Restated 2015 Stock and Incentive Plan are to attract and retain the best available personnel for positions of substantial responsibility, to provide additional incentive to Service Providers, and to promote the success of the Company

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 7, 2023 Illumina, Inc. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 7, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpora

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 1, 2023 Illumina, Inc. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 1, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpora

Form of Restricted Stock Unit Agreement for Employees Under Amended and Restated 2015 Stock and Incentive Plan

ILLUMINA, INC. AMENDED AND RESTATED 2015 STOCK AND INCENTIVE PLAN RESTRICTED STOCK UNIT AGREEMENT FOR EMPLOYEES This RESTRICTED STOCK UNIT AGREEMENT (this “Agreement”) made as of this day of , 20 , between Illumina, Inc., a Delaware corporation (the “Company”), and (the “Participant”), is made pursuant to the terms of the Company’s Amended and Restated 2015 Stock and Incentive Plan (the “Plan”). S

Form of Performance Stock Unit Agreement (Adjusted EPS) for Employees Under Amended and Restated 2015 Stock and Incentive Plan

EX-10.3 5 exhibit103formofperformanc.htm EX-10.3 ILLUMINA, INC. AMENDED AND RESTATED 2015 STOCK AND INCENTIVE PLAN PERFORMANCE STOCK UNIT AGREEMENT FOR EMPLOYEES This PERFORMANCE STOCK UNIT AGREEMENT (this “Agreement”) made as of this day of , 20 , between Illumina, Inc., a Delaware corporation (the “Company”), and (the “Participant”), is made pursuant to the terms of the Company’s Amended and Res

Amended and Restated Bylaws

BYLAWS OF ILLUMINA, INC. Amended and Restated as of February 1, 2023 TABLE OF CONTENTS ARTICLE I CORPORATE OFFICES 1 1.1 REGISTERED OFFICE 1 1.2 OTHER OFFICES 1 ARTICLE II MEETINGS OF STOCKHOLDERS 1 2.1 PLACE OF MEETINGS 1 2.2 ANNUAL MEETING 1 2.3 SPECIAL MEETING 1 2.4 NOTICE OF STOCKHOLDERS’ MEETINGS 3 2.5 MANNER OF GIVING NOTICE; AFFIDAVIT OF NOTICE 3 2.6 QUORUM 3 2.7 ADJOURNED MEETING; NOTICE 3

Illumina Reports Financial Results for Fourth Quarter and Fiscal Year 2022

Investors: Salli Schwartz +1.858.291.6421 [email protected] Media: David McAlpine +1.347.327.1336 [email protected] Illumina Reports Financial Results for Fourth Quarter and Fiscal Year 2022 •Revenue of $1.08 billion for Q4 2022, down 10% from Q4 2021, and down 7% on a constant currency basis •Revenue of $4.58 billion for fiscal year 2022, up 1% from fiscal year 2021, and up 3% on a constant currency

Illumina Appoints Joydeep Goswami Chief Financial Officer

Illumina Appoints Joydeep Goswami Chief Financial Officer SAN DIEGO, February 1, 2023 /PRNewswire/ - Illumina, Inc.

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 31, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpora

Illumina, Inc. Preliminary Results of Operations - Non-GAAP

Illumina, Inc. Preliminary Results of Operations - Non-GAAP (unaudited) Our performance and financial results are subject to risks and uncertainties, and actual results could differ materially from the preliminary results set forth below. Some of the factors that could affect our financial results are included from time to time in the public reports filed with the Securities and Exchange Commissio

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 9, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporat

CORPORATE PARTICIPANTS

CORPORATE PARTICIPANTS Francis A. deSouza; Illumina,Inc. - CEO & Director Joydeep Goswami; Illumina, Inc.- Chief Strategy & Corporate Development Officer and Interim CFO CONFERENCE CALL PARTICIPANTS Ruizhi Qin; JPMorgan Chase & Co, Research Division - Analyst PRESENTATION Ruizhi Qin All right. Good afternoon, everyone. Welcome to our next company presentation by Illumina. I'm Julia Qin, life scien

Illumina, Inc. Reconciliation of Non-GAAP Financial Guidance

Illumina, Inc. Reconciliation of Non-GAAP Financial Guidance (unaudited) Our future performance and financial results are subject to risks and uncertainties, and actual results could differ materially from the guidance set forth below. Some of the factors that could affect our financial results are included from time to time in the public reports filed with the Securities and Exchange Commission,

Entry into a Material Definitive Agreement, Termination of a Material Definitive Agreement, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 4, 2023 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporat

Credit Agreement, dated as of January 4, 2023, among the Company, as the borrower, the lenders from time to time party thereto, Bank of America, N.A., as administrative agent, an issuing bank and the swingline lender, and the other issuing banks from time to time party thereto

EX-10.1 2 d443370dex101.htm EX-10.1 Exhibit 10.1 EXECUTION VERSION CREDIT AGREEMENT dated as of January 4, 2023 among ILLUMINA, INC., as the Borrower, The Lenders Party Hereto, BANK OF AMERICA, N.A., as the Administrative Agent, an Issuing Bank, and the Swingline Lender, The Other Issuing Banks Party Hereto, JPMORGAN CHASE BANK, N.A., as the Syndication Agent, and CITIBANK, N.A., and GOLDMAN SACHS

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 13, 2022 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpor

Underwriting Agreement, dated November 29, 2022, between the Company and Goldman Sachs & Co. LLC and Citigroup Global Markets Inc., as representatives of the several underwriters named therein.

Exhibit 1.1 $1,000,000,000 Illumina, Inc. 5.800% Notes due 2025 5.750% Notes due 2027 Underwriting Agreement November 29, 2022 Goldman Sachs & Co. LLC Citigroup Global Markets Inc. As representatives (the ?Representatives?) of the several Underwriters named in Schedule I hereto c/o Goldman Sachs & Co. LLC 200 West Street New York, New York 10282-2198 c/o Citigroup Global Markets Inc. 388 Greenwich

Form of Officer’s Certificate setting forth the terms and forms of the 2025 Notes and 2027 Notes

Exhibit 4.2 Execution Version ILLUMINA, INC. OFFICER?S CERTIFICATE December 13, 2022 Reference is made to the Indenture dated as of March 12, 2021 (as so supplemented by this Officer?s Certificate, the ?Indenture?) by and between Illumina, Inc. (the ?Issuer?) and U.S. Bank Trust Company, National Association (as successor in interest to U.S. Bank National Association), as trustee (the ?Trustee?).

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 29, 2022 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpor

Carry Forward Form Type

Exhibit 107 Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Carry Forward Form Type Carry Forward File Number Carry Forward Initial effective date Filing Fee Previously Paid In Connection with Unsold Securities to be Carried Forward Newly Registered Securities Fees to Be Paid Debt 5.

$1,000,000,000 $500,000,000 5.800% Notes due 2025 $500,000,000 5.750% Notes due 2027

Table of Contents Filed Pursuant to Rule 424(b)(2) Registration Statement No. 333-254195 PROSPECTUS SUPPLEMENT (to Prospectus Dated March 12, 2021) $1,000,000,000 $500,000,000 5.800% Notes due 2025 $500,000,000 5.750% Notes due 2027 We are offering $500,000,000 aggregate principal amount of 5.800% notes due 2025 (the ?2025 Notes?) and $500,000,000 aggregate principal amount of 5.750% notes due 202

ILLUMINA, INC. FINAL TERM SHEET November 29, 2022 $500,000,000 5.800% Notes due 2025 $500,000,000 5.750% Notes due 2027 Issuer: Illumina, Inc. Format: SEC Registered Ratings* Moody’s: Baa3 (Stable) S&P: BBB (Stable) Fitch: BBB (Stable) Trade Date: No

Filed pursuant to Rule 433 Registration No. 333-254195 Issuer Free Writing Prospectus dated November 29, 2022 Relating to Preliminary Prospectus Supplement dated November 29, 2022 ILLUMINA, INC. FINAL TERM SHEET November 29, 2022 $500,000,000 5.800% Notes due 2025 $500,000,000 5.750% Notes due 2027 Issuer: Illumina, Inc. Format: SEC Registered Ratings* Moody?s: Baa3 (Stable) S&P: BBB (Stable) Fitc

Subject to Completion Preliminary Prospectus Supplement dated November 29, 2022

Table of Contents Filed Pursuant to Rule 424(b)(2) Registration Statement No. 333-254195 The information contained in this preliminary prospectus supplement is not complete and may be changed. This preliminary prospectus supplement and the accompanying prospectus are not an offer to sell the securities and are not soliciting an offer to buy the senior notes offered hereby in any jurisdiction where

Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 14, 2022 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpor

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ? Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended October 2, 2022 ? Transition Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the transition period from to Commission File Number 001-35406 Illumina, Inc. (Exact n

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 3, 2022 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpora

Illumina Reports Financial Results for Third Quarter of Fiscal Year 2022

Investors: Salli Schwartz +1.858.291.6421 [email protected] Media: David McAlpine +1.347.327.1336 [email protected] Illumina Reports Financial Results for Third Quarter of Fiscal Year 2022 ?Revenue of $1.12 billion for Q3 2022, up 1% from Q3 2021, and up 3% on a constant currency basis ?GAAP diluted loss per share of $(24.26) for Q3 2022, compared to GAAP diluted earnings per share of $2.08 for Q3 202

Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 5, 2022 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporat

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 29, 2022 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpo

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 14, 2022 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpo

Illumina Intends to Appeal European Commission’s Decision in GRAIL Deal

Exhibit 99.1 PRESS RELEASE Illumina Intends to Appeal European Commission?s Decision in GRAIL Deal SAN DIEGO, September 6, 2022 /PRNewswire/ - Illumina, Inc. (NASDAQ:ILMN), today received a decision from the European Commission prohibiting the company?s acquisition of GRAIL. The company is reviewing the Commission?s order and intends to appeal the decision. The EC decision follows last week?s ruli

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 6, 2022 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware (State or other jurisdiction of incorporation) 33-0

Amended and Restated Certificate of Incorporation

Amended and Restated Certificate of Incorporation of Illumina, Inc. Illumina, Inc., a corporation organized and existing under and by virtue of the laws of the State of Delaware (the ?corporation?), hereby certifies as follows: 1.The present name of the corporation is Illumina, Inc. The original Certificate of Incorporation of the corporation was filed with the Secretary of State of the State of D

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 11, 2022 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporat

Illumina Reports Financial Results for Second Quarter of Fiscal Year 2022

Investors: Salli Schwartz +1.858.291.6421 [email protected] Media: Sarah Shew +1.858.336.3157 [email protected] Illumina Reports Financial Results for Second Quarter of Fiscal Year 2022 ?Revenue of $1.16 billion for Q2 2022, up 3% from Q2 2021, and up 5% on a constant currency basis ?GAAP diluted loss per share of $(3.40) for Q2 2022, compared to GAAP diluted earnings per share of $1.26 for Q2 2021

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ? Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended July 3, 2022 ? Transition Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the transition period from to Commission File Number 001-35406 Illumina, Inc. (Exact name

Amended and Restated Bylaws

BYLAWS OF ILLUMINA, INC. Amended and Restated as of June 3, 2022 TABLE OF CONTENTS ARTICLE I CORPORATE OFFICES 1 1.1. REGISTERED OFFICE 1 1.2. OTHER OFFICES 1 ARTICLE II MEETINGS OF STOCKHOLDERS 1 2.1. PLACE OF MEETINGS 1 2.2. ANNUAL MEETING 1 2.3. SPECIAL MEETING 1 2.4. NOTICE OF STOCKHOLDERS? MEETINGS 4 2.5. MANNER OF GIVING NOTICE; AFFIDAVIT OF NOTICE 4 2.6. QUORUM 4 2.7. ADJOURNED MEETING; NOT

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 14, 2022 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporatio

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 8, 2022 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporation

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 26, 2022 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporation

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT Illumina, Inc. (Exact name of the registrant as specified in its charter) (Commission File Number)

SD 1 a2022sdform.htm SD UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT Illumina, Inc. (Exact name of the registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporation) (I.R.S. Employer Identification No.) 5200 Illumina Way, San Diego, CA 92122 (Address of pr

Conflict Minerals Report

Conflict Minerals Report Introduction: This Report has been prepared pursuant to Rule 13p-1 under the Securities Exchange Act of 1934, as amended, for the reporting period from January 1 to December 31, 2021.

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 6, 2022 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporation)

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 5, 2022 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorporation)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☑ Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended April 3, 2022 ☐ Transition Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the transition period from to Commission File Number 001-35406 Illumina, Inc. (Exact nam

Illumina Reports Financial Results for First Quarter of Fiscal Year 2022

EX-99.1 2 a1q22earningsrelease.htm EX-99.1 Investors: Salli Schwartz +1.858.291.6421 [email protected] Media: Sarah Shew +1.330.353.2512 [email protected] Illumina Reports Financial Results for First Quarter of Fiscal Year 2022 •Revenue of $1.22 billion for Q1 2022, up 12% from Q1 2021 •Earnings per diluted share (diluted EPS) of $0.55 for Q1 2022, compared to $1.00 for Q1 2021 •Non-GAAP diluted EP

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-A FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES PURSUANT TO SECTION 12(b) OR 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 ILLUMINA, INC. (Exact name of registrant as s

8-A12G 1 8-a12g.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-A FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES PURSUANT TO SECTION 12(b) OR 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 ILLUMINA, INC. (Exact name of registrant as specified in its charter) Delaware 33-0804655 (State of incorporation or organization) (I.R.S. Employer Identification No.) 5200 Il

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. 1)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. 1) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defi

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

DEFA14A 1 d348359ddefa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

DEF 14A 1 d246458ddef14a.htm DEF 14A Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defi

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UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No.

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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 10, 2022 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpor

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SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 6)* Name of issuer: Illumina Inc. Title of Class of Securities: Common Stock CUSIP Number: 452327109 Date of Event Which Requires Filing of this Statement: December 31, 2021 Check the appropriate box to designate the rule pursuant to which this Schedule is filed: ??Rule

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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 10, 2022 Illumina, Inc. (Exact name of registrant as specified in its charter) 001-35406 (Commission File Number) Delaware 33-0804655 (State or other jurisdiction of incorpora

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Amendment No. 2 SCHEDULE TO Tender Offer Statement Under Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 Illumina, Inc. (Name of Subject Company (Issuer) and Filing Person

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Amendment No. 2 to SCHEDULE TO Tender Offer Statement Under Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 Illumina, Inc. (Name of Subject Company (Issuer) and Filing Person (Offeror)) Contingent Value Rights N/A (Title of Class of Securities) (CUSIP Number of Class of Securities) Charles E. Dadswell Senior Vice Preside

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Amendment No. 1 SCHEDULE TO Tender Offer Statement Under Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 Illumina, Inc. (Name of Subject Company (Issuer) and Filing Person

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Amendment No. 1 to SCHEDULE TO Tender Offer Statement Under Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 Illumina, Inc. (Name of Subject Company (Issuer) and Filing Person (Offeror)) Contingent Value Rights N/A (Title of Class of Securities) (CUSIP Number of Class of Securities) Charles E. Dadswell Senior Vice Preside

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CORRESP 1 filename1.htm November 22, 2021 Via EDGAR Securities and Exchange Commission Division of Corporate Finance 100 F. Street, N.E. Washington, D.C. 20549 Attn: Perry Hindin Special Counsel Office of Mergers and Acquisitions Re: Illumina, Inc. Schedule TO-I filed November 15, 2021 SEC File No. 005-60457 Dear Mr. Hindin: On behalf of our client, Illumina, Inc. (the “Company”), we are submittin